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11. 发明申请

WO2006051413A1 AZABENOXAZOLES FOR THE TREATMENT OF CNS DISORDERS 审中-公开
标题翻译：用于治疗CNS病症的AZABENOXAZOLES
公开(公告)号：WO2006051413A1
公开(公告)日：2006-05-18
申请号：PCT/IB2005/003427
申请日：2005-11-04
申请人： PFIZER INC. , DUPLANTIER, Allen, Jacob , O'DONNELL, Christopher, John , ROGERS, Bruce, Nelsen , ZHANG, Lei
发明人： DUPLANTIER, Allen, Jacob , O'DONNELL, Christopher, John , ROGERS, Bruce, Nelsen , ZHANG, Lei
IPC分类号： C07D519/00 , A61K31/551 , A61P25/00 , A61P25/18 , A61P25/28
CPC分类号： C07D471/08
摘要： The present invention relates to a7 nicotinic receptor agonists of formula I as described herein and to a method for treating disorders of the Central Nervous System (CNS) and other disorders in a mammal, including a human, by administering to the mammal an a7 nicotinic receptor agonist of formula I. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier and a CNS-penetrant a7 nicotinic receptor agonist of formula (I).
摘要翻译：本发明涉及本文所述的式I的烟碱型受体激动剂和通过向哺乳动物施用a7烟碱样受体来治疗哺乳动物（包括人）中的中枢神经系统（CNS）和其它疾病的疾病的方法其还涉及含有药学上可接受的载体和式（I）的CNS渗透剂α7烟碱受体激动剂的药物组合物。

12. 发明申请

WO2006051394A1 AZABENZOXAZOLES FOR THE TREATMENT OF CNS DISORDERS 审中-公开
标题翻译：用于治疗CNS病症的AZABENZOXAZOLES
公开(公告)号：WO2006051394A1
公开(公告)日：2006-05-18
申请号：PCT/IB2005/003364
申请日：2005-11-03
申请人： PFIZER PRODUCTS INC. , DUPLANTIER, Allen, Jacob , KHASANOV, Alisher, Bakhadirovich , O'DONNELL, Christopher, John , ROGERS, Bruce, Nelsen , ZHANG, Lei
发明人： DUPLANTIER, Allen, Jacob , KHASANOV, Alisher, Bakhadirovich , O'DONNELL, Christopher, John , ROGERS, Bruce, Nelsen , ZHANG, Lei
IPC分类号： C07D519/00 , A61K31/551 , A61P25/18
CPC分类号： C07D519/00 , C07D498/04
摘要： The present invention relates to α7 nicotinic receptor agonists of formula (I) as described herein and to a method for treating disorders of the Central Nervous System (CNS) and other disorders in a mammal, including a human, by administering to the mammal an α7 nicotinic receptor agonist of formula (I). It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier and a CNS-penetrant α7 nicotinic receptor agonist of formula (I).
摘要翻译：本发明涉及本文所述的式（I）的烟碱型受体激动剂和通过向哺乳动物施用a7来治疗哺乳动物（包括人）中枢神经系统（CNS）和其它疾病的疾病的方法式（I）的烟碱受体激动剂。它还涉及包含药学上可接受的载体和式（I）的CNS渗透剂a7烟碱受体激动剂的药物组合物。

13. 发明申请

WO2004066777A3 ADJUSTABLE HAIR HOLDING DEVICE 审中-公开
标题翻译：可调节头发保持装置
公开(公告)号：WO2004066777A3
公开(公告)日：2006-03-09
申请号：PCT/US2004001761
申请日：2004-01-23
申请人： ROGERS BRUCE A , LIVINGSTON DAVID
发明人： ROGERS BRUCE A , LIVINGSTON DAVID
IPC分类号： A45D8/20 , A45D8/22 , A47L7/00
CPC分类号： A45D8/22
摘要： A hair holding device including hingedly connected first and second body members (212,214) each including hair gripping portions (222,224) adapted to be squeezed by a user whereby the hair gripping portions (222,224) come into contact with gathered strands of a user's hair. The device further includes a friction-type adjustment mechanism (238) coaxially arranged with respect to the hinge for causing the hair gripping portions (222,224) to remain at a point at which the hair gripping portions (222,224) are squeezed together by a user. Optionally, the device may include squeezable release handles (230,232) or other release mechanism, as well as a torsion spring (248) for biasing the hair gripping portions into either an open or a closed position.
摘要翻译：一种头发保持装置，包括铰接连接的第一和第二主体构件（212,214），每个主体构件包括适于被使用者挤压的头发夹持部分（222,224），由此毛发夹持部分（222,224）与使用者头发的聚集的线束接触。该装置还包括相对于铰链同轴布置的摩擦型调节机构（238），用于使头发夹持部分（222,224）保持在使用者将头发夹持部分（222,224）挤压在一起的点处。可选地，该装置可以包括可挤压释放手柄（230,232）或其它释放机构，以及用于将头发夹持部分偏压到打开或关闭位置的扭簧（248）。

14. 发明申请

WO2004066778A3 HAIR HOLDING DEVICE WITH ELASTIC CLOSURE OPERATION 审中-公开
标题翻译：具有弹性封闭操作的头发保持装置
公开(公告)号：WO2004066778A3
公开(公告)日：2005-03-24
申请号：PCT/US2004001763
申请日：2004-01-23
申请人： ROGERS BRUCE A
发明人： ROGERS BRUCE A
IPC分类号： A45D8/22 , A45D8/20 , A45D2/00 , A45D8/00 , A45D8/06 , A45D8/28 , A45D24/04
CPC分类号： A45D8/22
摘要： Novel hair holding devices having first and second pivotally connected body members including hair gripping portions, and methods for improving existing such hair holding devices, in which the improvement involves providing the lust and second body members with at least one elastomeric member (136) for biasing the first and second body members into a closed position and for conforming to gathered strands of user's hair when the hair gripping portions come into contact with gathered strands of a user's hair.
摘要翻译：具有包括头发夹持部分的第一和第二枢转连接的身体构件的新型头发夹持装置以及用于改进现有这种头发夹持装置的方法，其中改进包括为欲望和第二主体构件提供至少一个弹性构件（136）所述第一和第二主体部件处于关闭位置并且当所述头发夹持部分与使用者头发的聚集的线束接触时，用于与所述用户头发的聚集的线束一致。

15. 发明申请

WO2004071233A2 HAIR HOLDING DEVICE WITH CONCEALED SPRING 审中-公开
标题翻译：头发保持装置与隐形弹簧
公开(公告)号：WO2004071233A2
公开(公告)日：2004-08-26
申请号：PCT/US2004/002916
申请日：2004-02-02
申请人： ROGERS, Bruce, A.
发明人： ROGERS, Bruce, A. , LIVINGSTON, David
IPC分类号： A45D
CPC分类号： A45D8/20
摘要： A hair holding device and spring concealment mechanism including a pair of opposed, hingedly connected body members adapted to pivot about a hinge axis between closed and open positions. A torsion biasing spring biases the device into a predetermined position. The spring is concealed in multiple casings, which are unattached to either body member of the hair holding device. The casings do not bear any torque exerted by the spring and do not encase the entireties of the spring's first and second projecting arms. Consequently, they can be made relatively thin-walled and compact to closely conform to the size and shape of the coil portion of the spring. The thin walls and small diameter of the spring casings minimize the extent to which the casings protrude from the hair holding device, thereby improving its aesthetic appeal.
摘要翻译：一种头发夹持装置和弹簧隐蔽机构，包括一对相对的，铰接连接的本体构件，适于在闭合位置和打开位置之间围绕铰链轴线枢转。扭转偏压弹簧将装置偏压到预定位置。弹簧被隐藏在多个壳体中，这些壳体与头发夹持装置的任何一个主体部件无关。壳体不承受弹簧施加的任何扭矩，并且不包围弹簧的第一和第二突出臂的整体。因此，它们可以制成相对薄壁且紧凑，以与弹簧的线圈部分的尺寸和形状紧密地一致。弹簧壳体的薄壁和小直径使壳体从头发夹持装置突出的程度最小化，从而提高其美学吸引力。

16. 发明申请

WO2003093250A2 POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR 审中-公开
标题翻译： NICOTINIC乙酰胆碱受体的阳性免疫调节剂
公开(公告)号：WO2003093250A2
公开(公告)日：2003-11-13
申请号：PCT/US2003/011493
申请日：2003-04-28
申请人： PHARMACIA & UPJOHN COMPANY , PIOTROWSKI, David, W. , ROGERS, Bruce, N. , MCWHORTER, William, W., Jr. , WALKER, Daniel, P. , CORBETT, Jeffrey, W. , GROPPI, Vincent, E., Jr. , RUDMANN, Daniel, G.
发明人： PIOTROWSKI, David, W. , ROGERS, Bruce, N. , MCWHORTER, William, W., Jr. , WALKER, Daniel, P. , CORBETT, Jeffrey, W. , GROPPI, Vincent, E., Jr. , RUDMANN, Daniel, G.
IPC分类号： C07D285/00
CPC分类号： C07D213/75 , C07C275/34 , C07C275/40 , C07C323/44 , C07C335/18 , C07D231/16 , C07D231/40 , C07D233/88 , C07D261/14 , C07D277/48 , C07D277/56 , C07D277/82 , C07D285/135 , C07D413/12 , C07D417/12
摘要： The invention provides compounds of Formula I: (1) these compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which α7 nAChR is known to be involved.
摘要翻译：本发明提供式I化合物：（1）这些化合物可以是药物盐或组合物的形式，可以是纯对映体形式或外消旋混合物，并且可用于用于治疗其中α7nAChR为已知涉及。

17. 发明申请

WO1992005674A1 ELECTRICAL HEATING TAPE 审中-公开
标题翻译：电加热带
公开(公告)号：WO1992005674A1
公开(公告)日：1992-04-02
申请号：PCT/GB1991001587
申请日：1991-09-17
申请人： RAYCHEM LIMITED , N.V. RAYCHEM S.A. , CORDIA, Johannes, Maria , ROGERS, Bruce
发明人： RAYCHEM LIMITED , N.V. RAYCHEM S.A.
IPC分类号： H05B03/34
CPC分类号： B29C65/18 , B29C65/3444 , B29C65/3448 , B29C65/3488 , B29C65/3492 , B29C65/3496 , B29C66/1142 , B29C66/347 , B29C66/5221 , B29C66/71 , B29C66/81471 , B29C66/91411 , B29C66/91431 , B29C66/91651 , B29C66/91655 , H05B3/34 , H05B2203/005 , H05B2203/011 , H05B2203/013 , H05B2203/017 , H05B2203/037 , B29C65/00 , B29K2081/04 , B29K2079/08 , B29K2027/18 , B29K2023/0683 , B29K2023/06
摘要： A conductive polymeric tape has elongate electrodes (6), extending along its long edges, and comprises a central longitudinal strip (8) of different resistance to the remainder of the tape. The strip (8) extends part way only along the tape. The tape may also, or instead contain discontinuities (20) preferably extending across the tape. The purpose of the strip (8) and the discontinuities (20) is to control the passage of electrical current and also the heat output of different parts of the tape.
摘要翻译：导电聚合物带具有沿其长边缘延伸的细长电极（6），并且包括与磁带的其余部分不同的阻力的中心纵向条（8）。带（8）仅沿着带延伸。胶带还可以或者替代地包含不连续性（20），优选地延伸穿过带子。条（8）和不连续（20）的目的是控制电流的通过以及带的不同部分的热输出。

18. 发明申请

WO2008012622A2 AZABENZIMIDAZOLYL COMPOUNDS 审中-公开
标题翻译： AZABENZIMIDAZOLYL化合物
公开(公告)号：WO2008012622A2
公开(公告)日：2008-01-31
申请号：PCT/IB2007/002030
申请日：2007-07-13
申请人： PFIZER PRODUCTS INC. , EFREMOV, Ivan Viktorovich , ROGERS, Bruce Nelsen , DUPLANTIER, Allen, Jacob , ZHANG, Lei , ZHANG, Qian , MAKLAD, Noha Serour
发明人： EFREMOV, Ivan Viktorovich , ROGERS, Bruce Nelsen , DUPLANTIER, Allen, Jacob , ZHANG, Lei , ZHANG, Qian , MAKLAD, Noha Serour
IPC分类号： C07D471/04 , C07D487/04 , C07D519/00 , A61P25/00 , A61K31/4523
CPC分类号： C07D471/04 , C07D487/04 , C07D519/00
摘要： Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I), as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
摘要翻译：公开了化合物的化合物和药学上可接受的盐，其中化合物具有如说明书中定义的式（I）的结构。还公开了相应的药物组合物，治疗方法，合成方法和中间体。

19. 发明申请

WO2007135527A2 BENZIMIDAZOLYL COMPOUNDS 审中-公开
标题翻译：苯并咪唑化合物
公开(公告)号：WO2007135527A2
公开(公告)日：2007-11-29
申请号：PCT/IB2007001290
申请日：2007-05-14
申请人： PFIZER PROD INC , BERKE HELEN , DUPLANTIER ALLEN JACOB , EFREMOV IVAN , MCHARDY STANTON FURST , ROGERS BRUCE NELSEN , QIAN WEIMIN , ZHANG LEI , ZHANG QIAN
发明人： BERKE HELEN , DUPLANTIER ALLEN JACOB , EFREMOV IVAN , MCHARDY STANTON FURST , ROGERS BRUCE NELSEN , QIAN WEIMIN , ZHANG LEI , ZHANG QIAN
IPC分类号： C07D403/06 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14
CPC分类号： C07D403/06 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/06
摘要： Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of formula (I) or pharmaceutically acceptable salts thereof, wherein Y 1 , R 17 , R 2 , R 4 , R 5 , R 6 , R 7 , R 8 , X 2 and n are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
摘要翻译：公开了化合物的化合物和药学上可接受的盐，其中所述化合物具有式（I）的结构或其药学上可接受的盐，其中Y 1，R 17，R R 2，R 4，R 5，R 6，R 7，R 7，R 7，＆lt; SUP＆gt; 8＆gt;，＆lt; 2＆gt;和n如本发明的详细说明中所定义。还公开了相应的药物组合物，治疗方法，合成方法和中间体。

20. 发明申请

WO2005039297A1 TOASTED FLAVOR ADDITIVE 审中-公开
标题翻译：装饰风味添加剂
公开(公告)号：WO2005039297A1
公开(公告)日：2005-05-06
申请号：PCT/US2004/029937
申请日：2004-09-14
申请人： FRITO-LAY NORTH AMERICA, INC. , BAKER, Sheri, Lynn , MATHEW, John, Mampra , MATHEW, Renu , ROGERS, Bruce, Edward
发明人： BAKER, Sheri, Lynn , MATHEW, John, Mampra , MATHEW, Renu , ROGERS, Bruce, Edward
IPC分类号： A21D2/00
CPC分类号： A23L27/20 , A21D10/00 , A21D13/42 , A23L7/117 , A23L7/13 , A23L7/17 , A23L7/198 , Y10S426/808
摘要： A novel toasted flavor additive for enhancing the toasted flavor and appearance of food products. In accordance with one embodiment of the present invention, toasted corn flavor additive ("TCF") is made by the steps of cooking whole corn kernels in a solution of lime and water; steeping the corn; draining and washing the corn; grinding, sheeting and cutting the corn into pieces; toasting the pieces until significant browning has occurred beyond the level normally associated with consumed masa products; and grinding the toasted pieces into a powder that can be administered as toasted corn flavor additive.
摘要翻译：一种用于提高烘烤味道和食品外观的新颖风味添加剂。根据本发明的一个实施方案，通过在石灰和水的溶液中烹饪整个玉米粒子的步骤制备烤玉米风味添加剂（“TCF”）; 浸泡玉米; 排干和洗涤玉米; 研磨，成片并将玉米切成碎片; 烘烤片，直到显着的褐变发生超过通常与消费的masa产品相关的水平; 并将烘烤的碎片研磨成可以作为玉米风味添加剂施用的粉末。

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