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91. 发明申请

WO2010101633A2 ELASTICALLY STRETCHABLE FABRIC FORCE SENSOR ARRAYS AND METHODS OF MAKING 审中-公开
标题翻译：弹性可拉伸织物力传感器阵列和制造方法
公开(公告)号：WO2010101633A2
公开(公告)日：2010-09-10
申请号：PCT/US2010/000645
申请日：2010-03-03
申请人： TAYLOR, Geoffrey, L.
发明人： TAYLOR, Geoffrey, L.
IPC分类号： G01L1/18 , G01L5/04 , G01L5/00 , G01N3/08
CPC分类号： A47C27/082 , A61B5/1036 , A61B5/6892 , A61B2562/0247 , A61B2562/046 , G01L1/16 , G01L1/18 , G01L1/20 , G01L1/205 , G01L5/228 , G01N3/08 , G01N2203/0623 , H01L29/84
摘要： Force or pressure transducer arrays (30) have elastically stretchable electrically conductive polymer threads (31), (32) disposed in parallel rows and columns that contact at intersections thereof a piezoresistive material (37) which has an electrical resistivity that varies inversely with pressure or force exerted thereon to form a matrix array of force or pressure sensor elements. The threads are fixed to a single one or pair of flexible elastically stretchable substrate sheets (33), (35) made of thin sheets of an insulating polymer such as PVC, or for greater elasticity and conformability to irregularly- shaped objects such as human body parts, an elastically stretchable fabric such as LYCRA or SPANDEX. Elastic stretchability of the sensor arrays is optionally enhanced by disposing either or both row and column conductive threads (201-1), (201-2) in sinuously curved, serpentine paths rather than straight lines.
摘要翻译：力或压力传感器阵列（30）具有弹性伸缩的导电聚合物螺纹（31），（32），设置成平行的行和列，在其交点处接触压电材料（37），压电材料（37）具有与压力成反比变化的电阻率或施加在其上以形成力或压力传感器元件的矩阵阵列的力。螺纹被固定到由诸如PVC的绝缘聚合物的薄片制成的单个或一对柔性可弹性伸缩的基片（33），（35），或者对于诸如人体的不规则形状的物体具有更大的弹性和适应性零件，弹性伸缩织物如LYCRA或SPANDEX。任选地通过将行和列导电螺纹（201-1），（201-2）布置在弯曲曲线的蛇形路径中而不是直线来增强传感器阵列的弹性可拉伸性。

92. 发明申请

WO2010090706A2 POCKET-ENABLED CHIP ASSEMBLY FOR IMPLANTABLE DEVICES 审中-公开
标题翻译：用于可植入器件的口袋启用的芯片组件
公开(公告)号：WO2010090706A2
公开(公告)日：2010-08-12
申请号：PCT/US2010/000171
申请日：2010-01-21
申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY , TAI, Yu-Chong , HUANG, Ray, Kui-Jui
发明人： TAI, Yu-Chong , HUANG, Ray, Kui-Jui
IPC分类号： A61B5/024 , A61B5/0255 , A61M1/10
CPC分类号： A61B5/0031 , A61B5/04001 , A61B5/0478 , A61B5/6846 , A61B2562/0209 , A61B2562/028 , A61B2562/046 , A61N1/36003 , A61N1/36036 , A61N1/36046 , A61N1/375 , Y10T29/49117
摘要： Systems and methods for providing biologically compatible pockets or envelopes that can contain chips and other circuit elements and can make electrical connection between those elements and living organisms. The assembled biologically compatible pockets and circuit components can have biomedical applications, such as bioimplantable devices such as retinal, cochlear and cortical prosthesis implants, muscular stimulators, and other uses. In various embodiments, the described technology explains how to make and use pocket systems for dealing with chips having connectors on one or two surfaces, and with other circuit components such as resistors, capacitors, inductors and transistors. Operation of chips encapsulated according to the described technology is demonstrated. Accelerated life testing suggests that the pocket systems described will survive for years at 37 degrees C.
摘要翻译：用于提供生物相容口袋或包封的系统和方法，所述口袋或包封可以包含芯片和其他电路元件，并且可以在这些元件和生物体之间建立电连接。组装好的生物相容口袋和电路组件可以具有生物医学应用，诸如生物植入装置，诸如视网膜，耳蜗和皮质假体植入物，肌肉刺激器和其他用途。在各种实施例中，所描述的技术解释了如何制作和使用口袋系统来处理在一个或两个表面上具有连接器的芯片以及与诸如电阻器，电容器，电感器和晶体管的其他电路组件。演示了根据所述技术封装的芯片的操作。加速寿命测试表明，所描述的口袋系统将在37摄氏度下存活多年。

93. 发明申请

WO2010088696A1 NONINVASIVE DIAGNOSTIC SYSTEM 审中-公开
标题翻译：非侵入性诊断系统
公开(公告)号：WO2010088696A1
公开(公告)日：2010-08-05
申请号：PCT/US2010/022939
申请日：2010-02-02
申请人： MAHFOUZ, Mohamed, Rashwan
发明人： MAHFOUZ, Mohamed, Rashwan
IPC分类号： G06K9/00
CPC分类号： A61B5/04 , A61B5/0002 , A61B5/0004 , A61B5/002 , A61B5/0059 , A61B5/0488 , A61B5/1036 , A61B5/1038 , A61B5/11 , A61B5/1114 , A61B5/112 , A61B5/1121 , A61B5/1127 , A61B5/4528 , A61B5/4533 , A61B5/4585 , A61B5/6807 , A61B5/6828 , A61B5/6831 , A61B5/6833 , A61B5/72 , A61B5/7267 , A61B8/0858 , A61B8/0875 , A61B8/4227 , A61B8/4236 , A61B8/4254 , A61B8/4263 , A61B8/4472 , A61B8/4477 , A61B8/466 , A61B8/467 , A61B8/483 , A61B8/5223 , A61B8/5238 , A61B34/20 , A61B2034/105 , A61B2562/02 , A61B2562/0204 , A61B2562/0219 , A61B2562/0247 , A61B2562/046 , G06F19/00 , G06F19/3481 , G16H50/50
摘要： A method and system for diagnosing an injury to bodily tissue. The method of the present invention comprises in one embodiment creating a 3D model of a patient specific bone registering the patient actual bone with the patient-specific bone model, tracking the motion of the patient's bone through a range of motion, comparing the motion of the patient' s bone to a database having bone motion data to diagnose an injury, where the database has bone motion data teamed with verified diagnosis data
摘要翻译：一种诊断身体组织损伤的方法和系统。本发明的方法包括在一个实施方案中创建患者特定骨骼的3D模型，用患者特异性骨模型记录患者实际骨骼，通过运动范围跟踪患者骨骼的运动，患者的骨骼到具有骨骼运动数据的数据库以诊断损伤，其中数据库具有与经验证的诊断数据组合的骨骼运动数据

94. 发明申请

WO2010085526A1 CO-LOCATION OF EMITTERS AND DETECTORS AND METHOD OF OPERATION 审中-公开
标题翻译：发射器和探测器的合作位置及其操作方法
公开(公告)号：WO2010085526A1
公开(公告)日：2010-07-29
申请号：PCT/US2010/021584
申请日：2010-01-21
申请人： MEDTRONIC, INC. , KUHN, Jonathan, L. , ROBERTS, Jonathan, P. , RIES, Andrew, J. , REINKE, James D. , JELEN, Jeffrey, M. , ECKER, Robert, M. , DAVIS, Timothy, J. , CINBIS, Can , ANDERSON, Thomas A.
发明人： KUHN, Jonathan, L. , ROBERTS, Jonathan, P. , RIES, Andrew, J. , REINKE, James D. , JELEN, Jeffrey, M. , ECKER, Robert, M. , DAVIS, Timothy, J. , CINBIS, Can , ANDERSON, Thomas A.
IPC分类号： G06F19/00
CPC分类号： A61B5/1459 , A61B5/14542 , A61B5/1495 , A61B2562/0233 , A61B2562/046 , A61N1/36557 , G06F19/00 , G16H40/63
摘要： An implantable medical device having an optical sensor selects the function of modular opto-electronic assemblies included in the optical sensor. Each assembly is provided with at least one light emitting device and at least one light detecting device. A device controller coupled to the optical sensor controls the function of each the assemblies. The controller executes a sensor performance test and selects at least one of the plurality of assemblies to operate as a light emitting assembly in response to a result of the performance test. The controller selects at least one other of the plurality of optical sensor assemblies to operate as a light detecting assembly in response to a result of the performance test.
摘要翻译：具有光学传感器的可植入医疗装置选择包括在光学传感器中的模块化光电组件的功能。每个组件设置有至少一个发光装置和至少一个光检测装置。耦合到光学传感器的设备控制器控制每个组件的功能。控制器执行传感器性能测试，并且响应于性能测试的结果，选择多个组件中的至少一个作为发光组件进行操作。响应于性能测试的结果，控制器选择多个光学传感器组件中的至少一个以作为光检测组件进行操作。

95. 发明申请

WO2010055188A1 ELECTRODO PARA REGISTRO DE SEÑALES BIOELÉCTRICAS Y SU PROCEDIMIENTO DE FABRICACIÓN 审中-公开
标题翻译：用于记录生物电磁信号的电极及相关制造过程
公开(公告)号：WO2010055188A1
公开(公告)日：2010-05-20
申请号：PCT/ES2009/070501
申请日：2009-11-13
申请人： CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) , FUNDACIÓN DEL HOSPITAL NACIONAL DE PARAPLEJICOS PARA LA INVESTIGACIÓN Y LA INTEGRACIÓN (FUHNPAIIN) , MORENO, Berta , DEL CAMPO, Adolfo , VILLANUEVA, Eugenio , CHINARRO, Eva , JURADO, Jose Ramón , GUINEA, Domingo , OLIVIERO, Antonio , SOTO LEÓN, Vanesa , FOFFANI, Guglielmo
发明人： MORENO, Berta , DEL CAMPO, Adolfo , VILLANUEVA, Eugenio , CHINARRO, Eva , JURADO, Jose Ramón , GUINEA, Domingo , OLIVIERO, Antonio , SOTO LEÓN, Vanesa , FOFFANI, Guglielmo
IPC分类号： A61B5/0476 , A61B5/0478
CPC分类号： A61B5/0478 , A61B5/6814 , A61B2562/0209 , A61B2562/046
摘要： Electrodo (1) para el registro de las señales bioleléctricas de un paciente, que comprende: una matriz plana (2), que tiene una cara interior (2a) y una cara exterior(2b); al menos un soporte metálico (3) unido a la cara interior (2a) de la matriz plana (2); al menos una pieza elástica porosa (4), impregnada por una dispersión inorgánica conductora de la electricidad, que tiene una superficie de fijación (4b) fijada al soporte metálico (3) y una superficie de contacto (4a) para establecer contacto eléctrico con el cráneo del paciente.
摘要翻译：用于记录患者的生物电磁信号的电极（1），包括：具有内表面（2a）和外表面（2b）的平坦基体（2）; 连接到平坦基体（2）的内表面（2a）的至少一个金属支撑件（3）; 至少一个浸渍有无机导电分散体的多孔弹性部分（4），其具有固定到金属支撑体（3）的固定表面（4b）和接触表面（4a）以与患者的头骨建立电接触。

96. 发明申请

WO2010053617A2 SPECTROSCOPIC SENSORS 审中-公开
标题翻译：光谱传感器
公开(公告)号：WO2010053617A2
公开(公告)日：2010-05-14
申请号：PCT/US2009/053183
申请日：2009-08-07
申请人： UNIVERSITY OF MASSACHUSETTS , SOLLER, Babs R. , COATES, John , YANG, Ye , JIN, Chunguang
发明人： SOLLER, Babs R. , COATES, John , YANG, Ye , JIN, Chunguang
IPC分类号： A61B5/1455 , A61B5/145
CPC分类号： A61B5/1455 , A61B5/0082 , A61B5/145 , A61B5/14539 , A61B5/14552 , A61B5/412 , A61B5/6801 , A61B2562/0233 , A61B2562/0238 , A61B2562/0242 , A61B2562/04 , A61B2562/046
摘要： Disclosed herein are sensors that include: (a) a circuit board that includes an electronic processor; (b) a plurality of radiation sources, each source being attached to the circuit board; and (c) a spectral detector attached to the circuit board, the spectral detector being configured to analyze radiation derived from one or more of the plurality of radiation sources. During use, the sensors are configured to be worn on a portion of a body of a subject. The electronic processor is configured to cause two or more of the plurality of radiation sources to direct incident radiation to the subject, to cause the spectral detector to analyze radiation from the subject, and to determine one or more properties of the subject based on the radiation from the subject. Methods of making and using these sensors are also disclosed.
摘要翻译：这里公开的传感器包括：（a）包括电子处理器的电路板; （b）多个辐射源，每个源连接到电路板; 和（c）附着到电路板的光谱检测器，所述光谱检测器被配置为分析从多个辐射源中的一个或多个发射的辐射。在使用期间，传感器被配置成佩戴在被检体的身体的一部分上。电子处理器被配置为使得多个辐射源中的两个或更多个辐射源将入射辐射引导到对象，以使得光谱检测器分析来自对象的辐射，并且基于辐射来确定对象的一个或多个属性从主题。还公开了制造和使用这些传感器的方法。

97. 发明申请

WO2010044879A2 METHOD AND DEVICES FOR SELF ADJUSTING PHOTOTHERAPEUTIC INTERVENTION 审中-公开
标题翻译：用于自我调节摄影干预的方法和装置
公开(公告)号：WO2010044879A2
公开(公告)日：2010-04-22
申请号：PCT/US2009/005648
申请日：2009-10-16
申请人： EDMAN, Carl, Frederick , BHAVARAJU, Naresh, Chandra , DRINAN, Darrel, Dean
发明人： EDMAN, Carl, Frederick , BHAVARAJU, Naresh, Chandra , DRINAN, Darrel, Dean
IPC分类号： A61N5/06 , A61B6/00
CPC分类号： A61N5/0616 , A61B5/0059 , A61B5/0088 , A61B5/411 , A61B5/442 , A61B5/444 , A61B5/445 , A61B5/4839 , A61B2562/0233 , A61B2562/046 , A61N5/062 , A61N5/0624 , A61N2005/0653
摘要： The present invention are devices and the methods used by these devices that enable the determination of the physiological status of one or more body regions within a larger body zone, and the application of a therapy, preferably photonic therapy, based upon one or more sensor measurements, preferably photonic, used to determine the physiological status. Such applied photonic therapies may be accomplished in an effectively simultaneous fashion while being adjusted independently to each body region.
摘要翻译：本发明是这些装置使用的装置和方法，其能够确定较大身体区域内的一个或多个身体区域的生理状态，以及基于一个或多个传感器测量结果应用治疗，优选光子疗法，优选光子的，用于确定生理状态。这种应用的光子疗法可以以有效同时的方式实现，同时独立地调整到每个身体区域。

98. 发明申请

WO2010039864A2 FUNCTIONAL NEAR-INFRARED SPECTROSCOPY AS A MONITOR FOR DEPTH OF ANESTHESIA 审中-公开
标题翻译：作为ANESTHESIA深度监测仪的功能近红外光谱
公开(公告)号：WO2010039864A2
公开(公告)日：2010-04-08
申请号：PCT/US2009059074
申请日：2009-09-30
申请人： UNIV DREXEL , IZZETOGLU KURTULUS
发明人： IZZETOGLU KURTULUS
IPC分类号： A61B5/00
CPC分类号： A61B5/14552 , A61B5/14553 , A61B5/4821 , A61B5/7203 , A61B2562/0233 , A61B2562/046
摘要： Disclosed are methods and devices for measuring a state of anesthesia in a noninvasive manner. Optical techniques may be used to measure changes in a functional near-infrared (fNIR) signal, where the fNIR signal is received in response to directing wavelengths of light in a near-infrared range on a patient. The optical density change may be used to obtain a change in deoxyhemoglobin (deoxy-Hb) concentration and/or a change in an oxyhemoglobin concentration (oxy-Hb). The changes in the deoxy-Hb and/or the oxy-Hb may then be compared to determine a state of anesthesia. The effect of artifacts (e.g., strong surgery room lighting, patient-table tilting, patient intubation/extubation) on the fNIR signal may be removed using a noise removal algorithm. In selecting the noise removal algorithm, a switching technique may be used to select the component analysis algorithm, such as a principal component analysis (PCA), an independent component analysis (ICA), or the like.
摘要翻译：公开了用于以非侵入性方式测量麻醉状态的方法和装置。可以使用光学技术来测量功能性近红外（fNIR）信号的变化，其中响应于在患者的近红外范围内引导波长的波长而接收fNIR信号。可以使用光密度变化来获得脱氧血红蛋白（脱氧-Hb）浓度的变化和/或氧合血红蛋白浓度（oxy-Hb）的变化。然后可以比较脱氧-Hb和/或氧-Hb的变化以确定麻醉状态。可以使用噪声去除算法去除伪影（例如，强手术室照明，患者台倾斜，患者插管/拔管）对fNIR信号的影响。在选择噪声去除算法时，可以使用切换技术来选择分量分析算法，例如主分量分析（PCA），独立分量分析（ICA）等。

99. 发明申请

WO2010021898A1 METHOD AND APPARATUS FOR DISEASE DIAGNOSIS AND SCREENING USING EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELDS 审中-公开
标题翻译：使用极低频电磁场进行疾病诊断和筛选的方法和装置
公开(公告)号：WO2010021898A1
公开(公告)日：2010-02-25
申请号：PCT/US2009/053669
申请日：2009-08-13
申请人： FAUPEL, Mark, L.
发明人： FAUPEL, Mark, L.
IPC分类号： A61B5/04
CPC分类号： A61B5/04 , A61B5/7264 , A61B2562/0209 , A61B2562/046 , G06F19/00
摘要： Novel methods and apparatus for diagnosing or screening disease states in living organisms by the measurement and analysis of extremely low frequency electromagnetic fields, particularly extremely low frequency alternating current. The measurement of such fields is performed at a single point or at several test points on or in the body and compared to one or more reference. Information in the time-varying electromagnetic field is collected, then processed by diagnostic or screening algorithms to provide information about the disease state of the tissue being assessed.
摘要翻译：用于通过测量和分析极低频电磁场，特别是极低频交流电来诊断或筛选活体中疾病状态的新方法和装置。这些场的测量在单个点或身体上或身体上的几个测试点进行，并与一个或多个参考相比较。收集时变电磁场中的信息，然后通过诊断或筛选算法进行处理，以提供有关待评估组织的疾病状态的信息。

100. 发明申请

WO2009139911A3 ELECTRODE PATCH MONITORING DEVICE 审中-公开
标题翻译：电极配线监控装置
公开(公告)号：WO2009139911A3
公开(公告)日：2010-02-25
申请号：PCT/US2009003043
申请日：2009-05-15
申请人： HEARTSCAPE TECHNOLOGIES INC , PHILLIPS PAUL DAVID , MCGREGOR BRIAN , MCKEAN WESLEY JAMES
发明人： PHILLIPS PAUL DAVID , MCGREGOR BRIAN , MCKEAN WESLEY JAMES
IPC分类号： A61B5/0408 , A61B5/044
CPC分类号： A61B5/04085 , A61B5/7207 , A61B2562/0209 , A61B2562/046 , A61B2562/164
摘要： An electrode patch monitoring device that enables fast and accurate application is described. According to some embodiments, the electrode patch monitoring device comprises an array of electrodes for monitoring bioelectrical data that are formed on a flexible substrate. The electrode patch monitoring device may be available in a plurality of sizes, and various methods are provided for selecting an appropriate size according to the physiology of a patient. Methods for applying the electrode patch monitoring device to the patient's body are also provided.
摘要翻译：描述了能够快速准确应用的电极贴片监测装置。根据一些实施例，电极贴片监测装置包括用于监测形成在柔性基底上的生物电数据的电极阵列。电极贴片监测装置可以有多种尺寸，并且提供各种方法以根据患者的生理学来选择合适的尺寸。还提供了将电极贴片监测装置应用于患者身体的方法。

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