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    • 98. 发明申请
    • PREDICTIVE MODEL FOR USE IN SEQUENCING-BY-SYNTHESIS
    • 用于顺序合成的预测模型
    • WO2012058459A2
    • 2012-05-03
    • PCT/US2011/058134
    • 2011-10-27
    • LIFE TECHNOLOGIES CORPORATIONDAVEY, MelvilleMEYER, Michael
    • DAVEY, MelvilleMEYER, Michael
    • G06G7/58G06F19/20G06F7/60
    • G06F19/12C12Q1/6874C12Q2537/165
    • A method of obtaining a more accurate estimate of a signal correction parameter(s) in sequencing-by-synthesis operations, such as incomplete extension rates, carry forward rates, and/or signal droop rates. The sequencing operation produces signal data. A model is constructed to simulate a population of template strands as it undergoes the sequencing process and becomes divided into different phase-states as the sequencing-by-synthesis progresses. For example, the model may be a phase-state model. The output from the model is used to adjust the signal correction parameter(s). For example, the model may be fitted to the signal data. This fitting results in a more accurate estimate of the signal correction parameter(s). In another embodiment, the signal droop rate is modeled as a decaying function and this decaying function is fitted to the signal data to obtain an improved estimate of the signal droop rate.
    • 一种在逐个合成操作中获得信号校正参数的更精确估计的方法,例如不完全扩展速率,结转率和/或信号下降率。 排序操作产生信号数据。 构建模型以模拟模板链的群体,因为其经历了测序过程,并且随着逐个序列合成的进行而分为不同的相态。 例如,模型可以是阶段状态模型。 模型的输出用于调整信号校正参数。 例如,该模型可以适合于信号数据。 该拟合导致信号校正参数的更精确的估计。 在另一个实施例中,信号下降率被建模为衰减函数,并且该衰减函数适合于信号数据以获得信号下降率的改进估计。
    • 99. 发明申请
    • VERSATILE REMOTE CONTROL DEVICE, SYTEM AND METHOD
    • 多个远程控制装置,SYTEM和方法
    • WO2012044972A1
    • 2012-04-05
    • PCT/US2011/054291
    • 2011-09-30
    • TRANSMITIVE, LLCMEYER, MichaelCOLEMAN, Zane
    • MEYER, MichaelCOLEMAN, Zane
    • H04N21/422G08C17/02G08C23/04
    • H04N21/42226G08C17/02G08C23/04H04N21/42206
    • A radio-frequency (RF) remote control (10) has a user interface and transmits an RF signal (11) which designates a device (14) to be controlled and a command for that device. The RF signal is received by an intermediary device (12). The intermediary device, in turn, generates and broadcasts a plurality of high-power IR signals (13A-13F). These signals may be received directly by a controlled device (14A) or may be received indirectly by a controlled device (14B, 14C) after one or more reflections from objects (16A, 16B) and/or room surfaces (18). Thus, reliable control of the devices (14) is obtained even in situations where merely transmitting a typical IR signal may not provide reliable control of the device (14).
    • 射频(RF)遥控器(10)具有用户接口并且发送指定要控制的设备(14)的RF信号(11)和用于该设备的命令。 RF信号由中间设备(12)接收。 中继装置又产生并广播多个高功率红外信号(13A-13F)。 这些信号可以由受控设备(14A)直接接收,或者可以在从物体(16A,16B)和/或室内表面(18)进行的一次或多次反射之后由受控设备(14B,14C)间接接收。 因此,即使在仅发送典型的IR信号的情况下也不能提供对设备(14)的可靠控制的情况下,可以可靠地控制设备(14)。
    • 100. 发明申请
    • SIDE BRANCH WIRING ASSIST SHEATH AND METHODS
    • 侧支线接头护套和方法
    • WO2009152234A2
    • 2009-12-17
    • PCT/US2009/046885
    • 2009-06-10
    • BOSTON SCIENTIFIC SCIMED, INC.MEYER, MichaelDAVIS, Michael, Wayne
    • MEYER, MichaelDAVIS, Michael, Wayne
    • A61M25/00
    • A61M25/0105A61M25/0041A61M25/0054A61M25/0068
    • A vessel bifurcation wire assist device and related methods of advancing guidewires into main and branch vessels of a vessel bifurcation. The wire assist device includes a first guidewire housing member defining a first guidewire lumen sized to advance over a first guidewire, and a second guidewire housing member defining a second guidewire lumen sized to advance over a second guidewire. The second guidewire housing member has a first directional arrangement and a second directional arrangement. The first directional arrangement provides a parallel arrangement of the second guidewire relative to the first guidewire housing member, and the second directional arrangement provides an angled arrangement of the second guidewire relative to the first guidewire housing member.
    • 一种血管分叉线辅助装置以及将导丝推进血管分叉的主要和分支血管的相关方法。 线辅助装置包括第一导丝壳体构件,其限定尺寸设置成超过第一导丝的第一导丝管腔,以及限定第二导丝管腔的第二导丝壳体构件,其尺寸设计成在第二导丝上前进。 第二导线壳体构件具有第一方向布置和第二方向布置。 第一方向布置提供了第二导丝相对于第一导丝壳体构件的平行布置,并且第二方向布置提供了第二导丝相对于第一导丝壳体构件的成角度布置。