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91. 发明申请

WO1992013881A1 PEPTIDES 审中-公开
标题翻译：肽
公开(公告)号：WO1992013881A1
公开(公告)日：1992-08-20
申请号：PCT/AU1992000051
申请日：1992-02-12
申请人： LUMINIS PTY. LTD. , TYLER, Michael, James , BOWIE, John, Hamilton , STONE, David, James, Muir
发明人： LUMINIS PTY. LTD.
IPC分类号： C07K07/10
CPC分类号： C07K7/06 , A61K38/00 , C07K7/08 , C07K14/46
摘要： The first group of peptides of the invention are known as Caerins. These peptides have the formula: W-Gly-Leu-X-Z, wherein W is hydrogen, C1-6 alkyl, C6-10 aryl, C7-16 aralkyl or C1-20 acyl; X is a peptide sequence comprising 20 to 23 amino acid residues; and Z is hydroxy, amino, C1-6 alkylamino, di-(C1-6 alkyl)-amino, C1-18 alkoxy or C7-18 aralkoxy. Generally, Caerins have a molecular weight of between 2300 and 2700. The second group of peptides of the invention are known as Caeridins. These peptides have the formula: W-Gly-Leu-Y-Z, wherein W is hydrogen, C1-6 alkyl, C6-10 aryl, C7-16 aralkyl or C1-20 acyl; Y is a peptide sequence comprising 8 to 13 amino acid residues; and Z is hydroxy, amino, C1-6 alkylamino, di-(C1-6 alkyl)-amino, C1-18 alkoxy or C7-18 aralkoxy. Generally, Caeridins have a molecular weight of between 1100 and 1600. Representative members of both groups of peptides may be isolated from the skin or glands of Litoria splendida and Litoria caerulea. Some of the present peptides have potent physiological activity. For example, one of the Caerins has potent antibiotic activity against a variety of bacteria. Some of the peptides also have anti-viral activity, and may have anti-fungal activity. The peptides may also be used for food preservation.
摘要翻译：本发明的第一组肽被称为Caerins。这些肽具有下式：W-Gly-Leu-X-Z，其中W是氢，C 1-6烷基，C 6-10芳基，C 7-16芳烷基或C 1-20酰基; X是包含20-23个氨基酸残基的肽序列; 并且Z是羟基，氨基，C 1-6烷基氨基，二 - （C 1-6烷基） - 氨基，C 1-18烷氧基或C 7-18芳烷氧基。通常，Caerins的分子量在2300和2700之间。本发明的第二组肽被称为Caeridins。这些肽具有下式：W-Gly-Leu-Y-Z，其中W是氢，C 1-6烷基，C 6-10芳基，C 7-16芳烷基或C 1-20酰基; Y是包含8至13个氨基酸残基的肽序列; 并且Z是羟基，氨基，C 1-6烷基氨基，二 - （C 1-6烷基） - 氨基，C 1-18烷氧基或C 7-18芳烷氧基。一般来说，Caeridins的分子量在1100和1600之间。两组肽的代表性成员可以分离自spl藜和Litoria caerulea的皮肤或腺体。一些本发明的肽具有强烈的生理活性。例如，其中一种Caerins对各种细菌具有有效的抗生素活性。一些肽还具有抗病毒活性，并且可能具有抗真菌活性。肽也可用于食物保存。

92. 发明申请

WO2004061073A9 NOVEL HUMAN PROTEINS, POLYNUCLEOTIDES ENCODING THEM AND METHODS OF USING THE SAME 审中-公开
标题翻译：新人类蛋白质，编码它们的多核苷酸及其使用方法
公开(公告)号：WO2004061073A9
公开(公告)日：2013-10-31
申请号：PCT/US0224498
申请日：2002-08-02
申请人： CURAGEN CORP , GORMAN LINDA , ZERHUSEN BRYAN D , EDINGER SHLOMIT R , PADIGARU MURALIDHARA , GUO XIAOJIA , KEKUDA RAMESH , ZHONG MEI , PATTURAJAN MEERA , MILLER CHARLES E , JI WEIZHEN , PENA CAROL E A , BURGESS CATHERINE E , SCIORE PAUL , STONE DAVID J , TAUPIER RAYMOND J JR , CASMAN STACIE J , ROTHENBERG MARK E , MALYANKAR URIEL M , BOLDOG FERENC L
发明人： GORMAN LINDA , ZERHUSEN BRYAN D , EDINGER SHLOMIT R , PADIGARU MURALIDHARA , GUO XIAOJIA , KEKUDA RAMESH , ZHONG MEI , PATTURAJAN MEERA , MILLER CHARLES E , JI WEIZHEN , PENA CAROL E A , BURGESS CATHERINE E , SCIORE PAUL , STONE DAVID J , TAUPIER RAYMOND J JR , CASMAN STACIE J , ROTHENBERG MARK E , MALYANKAR URIEL M , BOLDOG FERENC L
IPC分类号： A61K38/00 , A61P3/00 , A61P3/10 , A61P9/00 , A61P9/10 , A61P17/06 , A61P21/00 , A61P31/00 , A61P35/00 , A61P37/00 , C07K14/47 , C07K14/705 , C12N1/19 , C12N1/21 , C12N5/02 , C12N5/08 , C12N15/12 , C12N15/16 , C12N15/18 , C12N15/19 , C12N15/53 , C12N15/54 , C12N15/57
CPC分类号： C07K14/705 , A61K38/00 , C07K14/47
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

93. 发明申请

WO2012170846A2 INTEGRATION OF WIRED INFORMATION AND WIRELESS INFORMATION TO LOCATE A WIRELESS DEVICE 审中-公开
标题翻译：集成有线信息和无线信息，以定位无线设备
公开(公告)号：WO2012170846A2
公开(公告)日：2012-12-13
申请号：PCT/US2012/041598
申请日：2012-06-08
申请人： ADC TELECOMMUNICATIONS, INC. , STONE, David , SYBESMA, Eric, W. , RESSLER, Kevin
发明人： STONE, David , SYBESMA, Eric, W. , RESSLER, Kevin
IPC分类号： H04W64/00 , G01S5/02
CPC分类号： H04W4/023 , H04L67/18 , H04W4/02 , H04W64/003
摘要： One embodiment described herein includes a method of determining the location of a wireless device. The method includes capturing wired information about layer one and layer two used by wired components in a network; capturing wireless information about a wireless device communicatively coupled to the network; integrating at least some of the wired information and the wireless information; and using the integrated wired information and wireless information to locate the wireless device.
摘要翻译：本文描述的一个实施例包括确定无线设备的位置的方法。该方法包括捕获网络中有线组件使用的有关第一层和第二层的有线信息; 捕获关于通信地耦合到所述网络的无线设备的无线信息; 整合有线信息和无线信息中的至少一些; 并使用集成的有线信息和无线信息来定位无线设备。

94. 发明申请

WO2010093988A3 INTER-NETWORKING DEVICES FOR USE WITH PHYSICAL LAYER INFORMATION 审中-公开
标题翻译：用于物理层信息的互联设备
公开(公告)号：WO2010093988A3
公开(公告)日：2010-12-09
申请号：PCT/US2010024184
申请日：2010-02-12
申请人： ADC TELECOMMUNICATIONS INC , RAZA MOHAMMAD , PATEL KAMLESH , ANDERSON JOHN , COFFEY JOSEPH , DAY MICHAEL , COBURN HUTCH , STONE DAVID
发明人： RAZA MOHAMMAD , PATEL KAMLESH , ANDERSON JOHN , COFFEY JOSEPH , DAY MICHAEL , COBURN HUTCH , STONE DAVID
IPC分类号： H04L12/56 , H04L12/28
CPC分类号： H04L49/15 , H01R13/6658 , H01R24/64 , H04L41/12 , H04L41/22 , H04L41/24 , H04L41/26 , H04L45/66 , H04L49/351 , H04L67/16
摘要： One exemplary embodiment is directed to an inter-networking device that performs at least one inter-networking function using physical layer information about the network of which the device is a part. Another exemplary embodiment is directed to capturing physical layer information about physical communication media that is attached to an inter-networking device. Another exemplary embodiment is directed to a technique for generating a spanning tree and/or forwarding database information for a plurality of switches in a network at a central location. The spanning tree and/or forwarding database information is generated at the central location using information including physical layer information about devices and physical communication media in the network. Another exemplary embodiment is directed to an ETHERNET physical layer device having integrated support for capturing physical layer information about the physical communication media connected to the ETHERNET physical layer device.
摘要翻译：一个示例性实施例涉及使用关于设备是其一部分的网络的物理层信息来执行至少一个网络间功能的联网设备。另一示例性实施例涉及捕获关于连接到网络间设备的物理通信媒体的物理层信息。另一示例性实施例涉及一种用于在中央位置的网络中生成生成树和/或转发用于多个交换机的数据库信息的技术。使用包括关于网络中的设备和物理通信介质的物理层信息的信息，在中心位置生成生成树和/或转发数据库信息。另一示例性实施例涉及具有集成支持以用于捕获关于连接到以太网物理层设备的物理通信介质的物理层信息的以太网物理层设备。

95. 发明申请

WO2009143187A3 SYSTEMS AND METHODS FOR REMOTING MULTIMEDIA PLUGIN CALLS 审中-公开
标题翻译：用于移除多媒体呼叫的系统和方法
公开(公告)号：WO2009143187A3
公开(公告)日：2010-01-28
申请号：PCT/US2009044566
申请日：2009-05-19
申请人： CITRIX SYSTEMS INC , STONE DAVID , RIVERA JUAN , TABARES MODESTO
发明人： STONE DAVID , RIVERA JUAN , TABARES MODESTO
IPC分类号： H04L29/08 , H04L29/06
CPC分类号： H04L67/025 , G06F9/547 , H04L65/1069 , H04L65/1096 , H04L67/28 , H04L67/2819 , H04L67/2876
摘要： Described are methods and systems for remotely providing calls issued to a multimedia plugin. A proxy plugin executing on a server can intercept calls issued by a container application on the server, to a multimedia plugin. The proxy plugin can then transmit the intercepted call to a plugin executing on a client. The multimedia plugin on the client can receive the call issued by container application and responsively generate graphical or multimedia content. Upon generating the multimedia or graphical content, the multimedia plugin can display the generated content within a plugin window on the client. In some instances, the proxy plugin responds to the call issued by the container application rather than forward the call to the multimedia plugin. In those instances, the proxy plugin retrieves content from cache and responds to the container application call with the retrieved content.
摘要翻译：描述了用于远程提供发给多媒体插件的呼叫的方法和系统。在服务器上执行的代理插件可以拦截由服务器上的容器应用程序发出的调用到多媒体插件。代理插件然后可以将拦截的调用传输到在客户机上执行的插件。客户端上的多媒体插件可以接收容器应用程序发出的呼叫，并响应生成图形或多媒体内容。在生成多媒体或图形内容时，多媒体插件可以在客户端的插件窗口内显示生成的内容。在某些情况下，代理插件会响应容器应用程序发出的调用，而不是将调用转发到多媒体插件。在这些情况下，代理插件从缓存中检索内容，并使用检索到的内容对容器应用程序调用进行响应。

96. 发明申请

WO2009135052A3 JAVA VIRTUAL MACHINE HAVING INTEGRATED TRANSACTION MANAGEMENT SYSTEM 审中-公开
标题翻译：具有集成交易管理系统的JAVA虚拟机
公开(公告)号：WO2009135052A3
公开(公告)日：2010-01-07
申请号：PCT/US2009042389
申请日：2009-04-30
申请人： KABIRA TECHNOLOGIES INC , LIND OTTO , PILE JONATHON C , SARMIENTO RAMIRO , SIFTER DANIEL J , STONE DAVID , ZANG XIGUANG , PHILLIPS MARK
发明人： LIND OTTO , PILE JONATHON C , SARMIENTO RAMIRO , SIFTER DANIEL J , STONE DAVID , ZANG XIGUANG , PHILLIPS MARK
IPC分类号： G06F9/455 , G06F9/44 , G06F15/16
CPC分类号： G06F9/466
摘要： A computing system is provided via which a specification of user-defined business logic of a desired transaction processing application may be provided, and the computing system ensures that a resulting configured system is fully transactional. The specification of user-defined business logic is provided as JAVA program instructions (or another programming language) which does not natively provide for specification of full transactionality. The business logic definition is processed to instantiate a subset of a plurality of possible service adaptors, to implement services of the transaction processing application. The instantiated service adaptors are such that, when executed, the arranged instantiated service adaptors will accomplish the business logic in conjunction with generic transaction processing logic. In addition, the arranged instantiated service adaptors are such that, when, when executed, the transaction processing application will be accomplished in a manner that is fully transactional.
摘要翻译：提供了一种计算系统，通过该计算系统可以提供期望的事务处理应用的用户定义的业务逻辑的规范，并且计算系统确保结果配置的系统是完全事务性的。用户定义的业务逻辑的规范作为JAVA程序指令（或另一种编程语言）提供，该程序指令本身不提供完整事务性的规范。处理业务逻辑定义以实例化多个可能的服务适配器的子集，以实现事务处理应用的服务。实例化的服务适配器使得当被执行时，排列的实例服务适配器将结合通用事务处理逻辑来完成业务逻辑。此外，所配置的实例服务适配器使得当执行时，事务处理应用将以完全事务性的方式来实现。

97. 发明申请

WO2008086482A3 LATERAL COLLECTION PHOTOVOLTAICS 审中-公开
标题翻译：横向收藏光伏
公开(公告)号：WO2008086482A3
公开(公告)日：2008-10-09
申请号：PCT/US2008050780
申请日：2008-01-10
申请人： SOLARITY INC , FONASH STEPHEN J , LI HANDONG , STONE DAVID
发明人： FONASH STEPHEN J , LI HANDONG , STONE DAVID
IPC分类号： H01L31/00
CPC分类号： H01L51/4213 , H01L31/022425 , H01L51/0037 , H01L51/4266 , Y02E10/549
摘要： Lateral collection photovoltaic (LCP) structures based on micro- and nano-collecting elements are used to collect photogenerated carriers. In one set of embodiments, the collecting elements are arrayed on a conducting substrate. In certain versions, the collecting elements are substantially perpendicular to the conductor. In another set of embodiments, the micro- or nano-scale collecting elements do not have direct physical and electrical contact to any conducting substrate. In one version, both anode and cathode electrodes are laterally arrayed. In another version, the collecting elements of one electrode are a composite wherein a conductor is separated by an insulator, which is part of each collector element, from the opposing electrode residing on the substrate. In still another version, the collection of one electrode structure is a composite containing both the anode and the cathode collecting elements for collection. An active material is positioned among the collector elements.
摘要翻译：使用基于微纳米收集元件的侧向收集光伏（LCP）结构来收集光生载流子。在一组实施例中，集合元件排列在导电衬底上。在某些形式中，收集元件基本上垂直于导体。在另一组实施例中，微尺度或纳米级收集元件不具有与任何导电衬底的直接物理和电接触。在一个版本中，阳极和阴极电极都是横向排列的。在另一个版本中，一个电极的收集元件是复合材料，其中导体由驻留在基底上的相对电极的绝缘体分隔开，绝缘体是每个集电器元件的一部分。在另一个版本中，一个电极结构的集合是包含用于收集的阳极和阴极收集元件的复合物。活性物质位于收集器元件之间。

98. 发明申请

WO2008086482A2 LATERAL COLLECTION PHOTOVOLTAICS 审中-公开
标题翻译：横向收藏光伏
公开(公告)号：WO2008086482A2
公开(公告)日：2008-07-17
申请号：PCT/US2008050780
申请日：2008-01-10
申请人： SOLARITY INC , FONASH STEPHEN J , LI HANDONG , STONE DAVID
发明人： FONASH STEPHEN J , LI HANDONG , STONE DAVID
IPC分类号： B32B7/00
CPC分类号： H01L51/4213 , H01L31/022425 , H01L51/0037 , H01L51/4266 , Y02E10/549
摘要： Lateral collection photovoltaic (LCP) structures based on micro- and nano-collecting elements are used to collect photogenerated carriers. In one set of embodiments, the collecting elements are arrayed on a conducting substrate. In certain versions, the collecting elements are substantially perpendicular to the conductor. In another set of embodiments, the micro- or nano-scale collecting elements do not have direct physical and electrical contact to any conducting substrate. In one version, both anode and cathode electrodes are laterally arrayed. In another version, the collecting elements of one electrode are a composite wherein a conductor is separated by an insulator, which is part of each collector element, from the opposing electrode residing on the substrate. In still another version, the collection of one electrode structure is a composite containing both the anode and the cathode collecting elements for collection. An active material is positioned among the collector elements.
摘要翻译：采用基于微米和纳米收集元件的横向收集光伏（LCP）结构来收集光生载流子。在一组实施例中，收集元件排列在导电基底上。在某些版本中，收集元件基本垂直于导体。在另一组实施例中，微米级或纳米级收集元件不具有与任何导电衬底的直接物理和电接触。在一个版本中，阳极和阴极都横向排列。在另一种形式中，一个电极的收集元件是复合物，其中导体由作为每个收集元件的一部分的绝缘体与位于基板上的相对电极分开。在又一个版本中，一个电极结构的集合是包含用于收集的阳极和阴极收集元件的复合物。活性材料位于收集器元件之间。

99. 发明申请

WO2007067512A3 METHOD FOR IDENTIFYING MODULATORS OF ADPRH USEFUL FOR TREATING ALZHEIMER'S DISEASE 审中-公开
标题翻译：鉴定用于治疗阿尔茨海默病的ADPRH调节剂的方法
公开(公告)号：WO2007067512A3
公开(公告)日：2007-12-13
申请号：PCT/US2006046331
申请日：2006-12-04
申请人： MERCK & CO INC , MAJERCAK JOHN M , RAY WILLIAM J , STONE DAVID J
发明人： MAJERCAK JOHN M , RAY WILLIAM J , STONE DAVID J
IPC分类号： C07K16/40
CPC分类号： C07K16/40 , C12Q1/34 , G01N33/6893 , G01N2800/2821
摘要： Methods for identifying modulators of ADPRH are described. The methods are particularly useful for identifying analytes that antagonize ADPRH 's effect on processing of amyloid precursor protein to AjS peptide and thus useful for identifying analytes that can be used for treating Alzheimer disease.
摘要翻译：描述了用于鉴定ADPRH调节剂的方法。该方法特别可用于鉴定拮抗ADPRH对Aβ淀粉样蛋白前体蛋白加工的影响的分析物，因此可用于鉴定可用于治疗阿尔茨海默病的分析物。

100. 发明申请

WO2006013352A1 SECURITY DEVICE 审中-公开
标题翻译：安全装置
公开(公告)号：WO2006013352A1
公开(公告)日：2006-02-09
申请号：PCT/GB2005/003030
申请日：2005-08-02
申请人： DE LA RUE INTERNATIONAL LIMITED , STONE, David, Allen , WILLIAMS, Wendy, Victoria
发明人： STONE, David, Allen , WILLIAMS, Wendy, Victoria
IPC分类号： B42D15/00
CPC分类号： B41M3/148 , B42D25/00 , B42D25/29 , B42D2035/24 , B42D2035/34
摘要： A pub is recognition security device comprises a planar substrate providing first and second areas. Each area has a printed, raised line structure of spaced apart lines with a background filling the spaces between the lines. The visual colour appearance of the lines (1a, 2a) is different to that of the background (1b, 2b) and the visual colour appearances of the respective backgrounds (1b, 2b) and/or of the respective line structures of the two areas differ from one another. When viewed by an observer perpendicularly to the substrate, the resultant visual colour appearances of the two areas is a combination of that of the respective background and raised line structure of each area and appear substantially the same. When viewed by an observer at an oblique angle, the resultant visual colour appearances of the two areas differ from one another due to at least part of the backgrounds being obscured by the corresponding raised line structures, the change in the resultant visual colour appearances of the two areas being indicative of the device authenticity.
摘要翻译：酒吧是识别安全设备，包括提供第一和第二区域的平面基板。每个区域具有打印的线条结构，其具有间隔开的线，背景填充线之间的空间。线（1a，2a）的视觉颜色外观与背景（1b，2b）的视觉颜色外观和两个背景（1b，2b）和/或各个背景（1b，2b）的各个线结构的视觉颜色外观不同彼此不同当观察者垂直于基底观察时，两个区域的所得到的视觉颜色外观是各区域的各自的背景和凸起线结构的组合，并且看起来基本相同。当观察者以斜角观察时，由于至少部分背景被相应的凸起线结构遮蔽，两个区域的合成视觉颜色外观彼此不同，所得到的视觉颜色外观的变化两个区域表示设备的真实性。

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