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    • 92. 发明申请
    • UPPER STOMACH GASTRIC IMPLANTS
    • 上部胃癌植入物
    • WO2012054411A2
    • 2012-04-26
    • PCT/US2011/056606
    • 2011-10-18
    • ALLERGAN, INC.BABKES, Mitchell H.DOMINGUEZ, Zachary P.
    • BABKES, Mitchell H.DOMINGUEZ, Zachary P.
    • A61F5/00
    • A61F5/0036A61F5/0033A61F5/0079
    • A variety of passive intragastric implant devices for obesity treatment are disclosed. Such passive devices do not autonomously change shape, but instead react within the stomach to induce satiety. The devices may provide slowed entry into the stomach, thus reducing the intake capacity. Additionally, the devices may contact areas within the stomach, such as the cardia surrounding the esophageal sphincter, to stimulate satiety-inducing nerves. Some devices combine two or more of these satiety-inducing features. Methods of implant are disclosed including compressing the devices within a delivery tube and transorally advancing the devices through the esophagus to be deployed within the stomach. Removal of the devices occurs in the reverse. The implants are formed of materials that permit the implant to be compressed into a substantially linear transoral delivery configuration and that will resist degradation over a period of at least six months within the stomach.
    • 公开了用于肥胖治疗的各种被动胃内植入装置。 这种被动装置不会自动改变形状,而是在胃内反应以引起饱腹感。 这些装置可能会减缓进入胃部的速度,从而降低进气量。 另外,装置可以接触胃内的区域,例如围绕食道括约肌的贲门,以刺激引起饱腹感的神经。 一些装置结合了两种或更多种这些引起饱腹感的特征。 公开了植入方法,包括压缩输送管内的装置并且经由食道经口腔推进装置以部署在胃内。 反过来拆除设备。 植入物由允许植入物被压缩成基本上线性的经口输送构造并且在胃内至少六个月内抵抗降解的材料形成。
    • 94. 发明申请
    • ELEVATING STOMACH STIMULATION DEVICE
    • 提醒胃刺激设备
    • WO2012054300A2
    • 2012-04-26
    • PCT/US2011/056175
    • 2011-10-13
    • ALLERGAN, INC.BABKES, Mitchell H.
    • BABKES, Mitchell H.
    • A61F5/00
    • A61F5/0043A61F5/003A61F5/0036
    • The medical systems, apparatuses and uses thereof for treating obesity and/or obesity-related diseases are provided which relate to devices designed to stimulate an internal surface of the stomach such as the cardia. Features of the obesity treatment devices include insertion of said devices transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The devices include flotation portions and cardia-stimulating portions, so that as the level of stomach contents rise, the devices will contact and stimulate the nerves in the cardia region of the stomach to induce satiety. The devices may have non-inflatable balls, be made of skinned foam, have ballast members such as a weighted ball or quantity of saline for orientation, and various combinations thereof.
    • 提供了用于治疗肥胖症和/或肥胖症相关疾病的医疗系统,设备和用途,其涉及设计用于刺激胃内部表面如贲门的装置。 肥胖治疗装置的特征包括经口插入所述装置并且没有侵入性手术,没有相关的患者侵入性手术风险,并且没有实质性的患者不适。 这些装置包括浮动部分和贲门刺激部分,从而随着胃内容物水平上升,装置将接触并刺激胃的贲门区域中的神经以引起饱腹感。 这些装置可以具有不可充气的球体,由表皮泡沫制成,具有诸如加重球的压载构件或用于取向的量的盐水,以及它们的各种组合。