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91. 发明申请

WO2012054598A2 NON-INFLATABLE GASTRIC IMPLANTS AND SYSTEMS 审中-公开
标题翻译：不可燃气体植入物和系统
公开(公告)号：WO2012054598A2
公开(公告)日：2012-04-26
申请号：PCT/US2011/056880
申请日：2011-12-02
申请人： ALLERGAN, INC. , BABKES, Mitchell H. , DOMINGUEZ, Zachary P. , SCHWAB, Justin J. , HOOVER, Jason
发明人： BABKES, Mitchell H. , DOMINGUEZ, Zachary P. , SCHWAB, Justin J. , HOOVER, Jason
CPC分类号： A61F5/0036 , A61F5/0089
摘要： A variety of passive intragastric implant devices for obesity treatment are disclosed. Such passive devices do not autonomously change shape, but instead react within the stomach to induce satiety. The devices may take up volume within the stomach, thus reducing the intake capacity. Additionally, the devices may contact areas within the stomach, such as the cardia surrounding the esophageal sphincter, or the greater and lesser curvatures in the middle of the stomach, to stimulate satiety-inducing nerves. Some devices may combine two or more of these satiety-inducing features. Methods of implant are disclosed including compressing the devices within a delivery tube and transorally advancing the devices through the esophagus to be deployed within the stomach. Removal of the devices occurs in the reverse.
摘要翻译：公开了用于肥胖症治疗的各种被动胃内植入装置。这种被动装置不会自主地改变形状，而是在胃内反应以引起饱腹感。这些装置可能占据胃内的体积，从而降低进气能力。另外，装置可以接触胃内的区域，例如围绕食管括约肌的贲门，或胃中部的较大和较小的曲率，以刺激饱腹引起的神经。一些装置可以组合这些饱腹感诱发特征中的两种或更多种。公开了植入物的方法，包括压缩输送管内的装置并且经由食道经过胃内部署的装置经过前进。相反的移除设备。

92. 发明申请

WO2012054411A2 UPPER STOMACH GASTRIC IMPLANTS 审中-公开
标题翻译：上部胃癌植入物
公开(公告)号：WO2012054411A2
公开(公告)日：2012-04-26
申请号：PCT/US2011/056606
申请日：2011-10-18
申请人： ALLERGAN, INC. , BABKES, Mitchell H. , DOMINGUEZ, Zachary P.
发明人： BABKES, Mitchell H. , DOMINGUEZ, Zachary P.
IPC分类号： A61F5/00
CPC分类号： A61F5/0036 , A61F5/0033 , A61F5/0079
摘要： A variety of passive intragastric implant devices for obesity treatment are disclosed. Such passive devices do not autonomously change shape, but instead react within the stomach to induce satiety. The devices may provide slowed entry into the stomach, thus reducing the intake capacity. Additionally, the devices may contact areas within the stomach, such as the cardia surrounding the esophageal sphincter, to stimulate satiety-inducing nerves. Some devices combine two or more of these satiety-inducing features. Methods of implant are disclosed including compressing the devices within a delivery tube and transorally advancing the devices through the esophagus to be deployed within the stomach. Removal of the devices occurs in the reverse. The implants are formed of materials that permit the implant to be compressed into a substantially linear transoral delivery configuration and that will resist degradation over a period of at least six months within the stomach.
摘要翻译：公开了用于肥胖治疗的各种被动胃内植入装置。这种被动装置不会自动改变形状，而是在胃内反应以引起饱腹感。这些装置可能会减缓进入胃部的速度，从而降低进气量。另外，装置可以接触胃内的区域，例如围绕食道括约肌的贲门，以刺激引起饱腹感的神经。一些装置结合了两种或更多种这些引起饱腹感的特征。公开了植入方法，包括压缩输送管内的装置并且经由食道经口腔推进装置以部署在胃内。反过来拆除设备。植入物由允许植入物被压缩成基本上线性的经口输送构造并且在胃内至少六个月内抵抗降解的材料形成。

93. 发明申请

WO2012054410A3 INTRAGASTRIC IMPLANTS WITH MULTIPLE FLUID CHAMBERS 审中-公开
公开(公告)号：WO2012054410A3
公开(公告)日：2012-04-26
申请号：PCT/US2011/056605
申请日：2011-10-18
申请人： ALLERGAN, INC. , BABKES, Mitchell H. , DOMINGUEZ, Zachary P. , MUDD, Christopher S. , OLROYD, Craig , D'AUGUSTA, Jonathan M.
发明人： BABKES, Mitchell H. , DOMINGUEZ, Zachary P. , MUDD, Christopher S. , OLROYD, Craig , D'AUGUSTA, Jonathan M.
IPC分类号： A61F5/00 , A61B10/00
摘要： An intragastric obesity treatment implant promotes a feeling of satiety in the patient by contacting the insides of the stomach wall, reducing the space in the stomach, or otherwise reducing the amount of food consumed. One intragastric obesity treatment implant two inflatable balloons coupled via a flow restrictor through which fluid may flow in response to peristaltic motions of a patient's stomach. Additionally, one implant comprises a pumping chamber coupled to a reservoir, where the pumping chamber moves stomach fluids into the reservoir in response to peristaltic motions of the patient's stomach.

94. 发明申请

WO2012054300A2 ELEVATING STOMACH STIMULATION DEVICE 审中-公开
标题翻译：提醒胃刺激设备
公开(公告)号：WO2012054300A2
公开(公告)日：2012-04-26
申请号：PCT/US2011/056175
申请日：2011-10-13
申请人： ALLERGAN, INC. , BABKES, Mitchell H.
发明人： BABKES, Mitchell H.
IPC分类号： A61F5/00
CPC分类号： A61F5/0043 , A61F5/003 , A61F5/0036
摘要： The medical systems, apparatuses and uses thereof for treating obesity and/or obesity-related diseases are provided which relate to devices designed to stimulate an internal surface of the stomach such as the cardia. Features of the obesity treatment devices include insertion of said devices transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The devices include flotation portions and cardia-stimulating portions, so that as the level of stomach contents rise, the devices will contact and stimulate the nerves in the cardia region of the stomach to induce satiety. The devices may have non-inflatable balls, be made of skinned foam, have ballast members such as a weighted ball or quantity of saline for orientation, and various combinations thereof.
摘要翻译：提供了用于治疗肥胖症和/或肥胖症相关疾病的医疗系统，设备和用途，其涉及设计用于刺激胃内部表面如贲门的装置。肥胖治疗装置的特征包括经口插入所述装置并且没有侵入性手术，没有相关的患者侵入性手术风险，并且没有实质性的患者不适。这些装置包括浮动部分和贲门刺激部分，从而随着胃内容物水平上升，装置将接触并刺激胃的贲门区域中的神经以引起饱腹感。这些装置可以具有不可充气的球体，由表皮泡沫制成，具有诸如加重球的压载构件或用于取向的量的盐水，以及它们的各种组合。

95. 发明申请

WO2011137242A1 SYSTEM FOR DETERMINING THE PRESSURE OF A FLUID IN A SYRINGE, AN ACCESS PORT, A CATHETER, AND A GASTRIC BAND 审中-公开
标题翻译：用于确定灌注液中的流体的压力的系统，进气口，导管和气体带
公开(公告)号：WO2011137242A1
公开(公告)日：2011-11-03
申请号：PCT/US2011/034320
申请日：2011-04-28
申请人： ALLERGAN, INC. , AUGARTEN, Mike , SNOW, Sean
发明人： AUGARTEN, Mike , SNOW, Sean
IPC分类号： A61F5/00
CPC分类号： A61F5/0056 , A61B90/37 , A61F5/0059 , A61M5/486 , A61M2005/3125 , A61M2205/3569 , A61M2205/3592 , A61M2205/505 , A61M2205/52
摘要： A method and system for determining pressure in a syringe, and more specifically to a syringe pressure accessory which can be connected to a syringe to determine pressure in a syringe and a gastric band. The syringe pressure accessory can detect a pressure of a syringe and/or a gastric band and digitally display the pressure. The syringe pressure accessory can include a durable unit and a disposable unit. The disposable unit can be disposed of after a single use, while the durable unit can be reused with multiple disposable units. The syringe pressure accessory can also include a syringe attachment unit and one or more display units for a caretaker or a patient. The display unit can be wirelessly connected to the syringe attachment unit to display a pressure chart or the results of various analysis of the pressure data. Markers can be added to the pressure chart.
摘要翻译：一种用于确定注射器中的压力的方法和系统，更具体地涉及可以连接到注射器以确定注射器和胃带中的压力的注射器压力附件。注射器压力附件可以检测注射器和/或胃带的压力并且数字显示压力。注射器压力附件可以包括耐用单元和一次性单元。一次性单元可以在一次使用之后被处理，而耐用单元可以重复使用多个一次性单元。注射器压力附件还可以包括注射器附接单元和用于看守者或患者的一个或多个显示单元。显示单元可以无线地连接到注射器附接单元以显示压力图或压力数据的各种分析的结果。标记可以添加到压力表。

96. 发明申请

WO2011097451A1 IMPLANTABLE SUBCUTANEOUS ACCESS PORT 审中-公开
标题翻译：可伸缩的小型通道
公开(公告)号：WO2011097451A1
公开(公告)日：2011-08-11
申请号：PCT/US2011/023709
申请日：2011-02-04
申请人： ALLERGAN, INC. , RAVEN, Joseph S. , TRILOKEKAR, Nikhil , CHITRE, Kaustubh
发明人： RAVEN, Joseph S. , TRILOKEKAR, Nikhil , CHITRE, Kaustubh
IPC分类号： A61M39/02 , A61M39/04 , A61F5/00
CPC分类号： A61F5/0056 , A61M39/0208 , A61M39/04 , A61M2039/022 , A61M2039/0223 , A61M2039/0226 , A61M2039/0238
摘要： The present invention generally provides a gastric banding system, including an implantable access port having a substantially ellipsoid shape. The access port is pliable and smooth, to increase the comfort of the access port to the patient, and to increase the aesthetic effect of the access port. The ellipsoid shape provides a large needle penetrable surface area for the access port, and enhances the ability of a physician to detect the access port through tactile means. A mesh layer may be incorporated in the housing of the access port, to increase durability of the housing, and to promote the self-sealing properties of the housing.
摘要翻译：本发明通常提供一种胃束带系统，其包括具有基本椭圆形状的可植入进入口。进出口是柔软而平稳的，以增加对病人的进入口的舒适性，并增加入口的美观效果。椭圆形状为入口提供了大的针穿透表面积，并且增强了医师通过触觉手段检测进入口的能力。网状层可以结合在进出口的壳体中，以增加壳体的耐久性，并提高壳体的自密封特性。

97. 发明申请

WO2011031854A1 PROSTHETIC DEVICE AND METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：前置装置及其制造方法
公开(公告)号：WO2011031854A1
公开(公告)日：2011-03-17
申请号：PCT/US2010/048263
申请日：2010-09-09
申请人： ALLERGAN, INC. , ALTMAN, Gregory H. , MORTARINO, Enrico
发明人： ALTMAN, Gregory H. , MORTARINO, Enrico
IPC分类号： A61F2/08 , A61F2/12
CPC分类号： A61F2/08 , A61F2/0811 , A61F2/12 , A61F2002/0858 , A61F2002/087 , A61F2002/0888 , D04B1/16 , D04B21/16 , D10B2211/22 , D10B2403/0311 , D10B2509/00
摘要： An implantable device for use in tissue and ligament repair comprising at least one knitted section (132, 134) and at least one single continuous fiber (122) traversing the at least one knitted section, the at least one single continuous fiber forming a plurality of traverses extending through the at least one knitted section. The implantable device may comprise at least one single continuous silk fiber. The implantable device is suitable for use in a variety or reconstructive or support applications such as breast reconstruction, mastoplexy, breast augmentation revision, breast augmentation support, standard breast augmentation, chest wall repair, organ support, body contouring, abdominoplasty, facial reconstruction, hernia repair, and pelvic floor repair.
摘要翻译：一种用于组织和韧带修复的可植入装置，包括至少一个针织部分（132,134）和穿过所述至少一个针织部分的至少一个单一连续纤维（122），所述至少一个单一连续纤维形成多个穿过至少一个针织部分延伸。可植入装置可以包括至少一个单一的连续丝纤维。可植入装置适用于多种或重建或支持应用，如乳房重建，乳腺增生，乳房增大修复，乳房增大支持，标准胸部增大，胸壁修复，器官支撑，身体轮廓，腹部成形术，面部重建，疝气修复和盆底修复。

98. 发明申请

WO2008134644A1 HIGH VISCOSITY MACROMOLECULAR COMPOSITIONS FOR TREATING OCULAR CONDITIONS 审中-公开
标题翻译：用于治疗眼睛病症的高粘度大分子组合物
公开(公告)号：WO2008134644A1
公开(公告)日：2008-11-06
申请号：PCT/US2008/061785
申请日：2008-04-28
申请人： ALLERGAN, INC. , HUGHES, Patrick, M. , DEVRIES, Gerald, W. , LYONS, Robert, T. , TROGDEN, John, T. , WHITCUP, Scott, M.
发明人： HUGHES, Patrick, M. , DEVRIES, Gerald, W. , LYONS, Robert, T. , TROGDEN, John, T. , WHITCUP, Scott, M.
IPC分类号： A61K31/713 , A61K38/39 , A61K39/395 , A61K47/36 , A61P27/02
CPC分类号： C07K16/22 , A61K9/0048 , A61K9/08 , A61K38/39 , A61K47/34 , A61K2039/505 , C07K2317/24 , C12N15/1138 , C12N2310/14 , C12N2310/315 , C12N2310/317 , C12N2310/332 , C12N2320/32
摘要： Anti-angiogenesis compositions, and methods of using such compositions, useful for injection into the vitreous of human eyes are provided. Such compositions include MAAC solutions or particles present in a therapeutically effective amount, a viscosity-inducing component, and an aqueous carrier component. The compositions have viscosities at about 250C. of at least about 10 cps or about 100 cps at a shear rate of 0. I/second. In a preferred embodiment, the viscosity at 25°C. is in the range of from about 80,000 cps to about 300,000 cps.
摘要翻译：提供抗血管生成组合物，以及使用这些组合物的方法，其可用于注射到人眼玻璃体中。这样的组合物包括以治疗有效量存在的MAAC溶液或颗粒，粘度诱导组分和水性载体组分。组合物的粘度在约25℃。在0.1 I /秒的剪切速率下为至少约10cps或约100cps。在优选的实施方案中，在25℃下的粘度。在约80,000cps至约300,000cps的范围内。

99. 发明申请

WO2008091810A1 SUBSTITUTED ARYLCYLOPENTENES AS THERAPEUTIC AGENTS 审中-公开
标题翻译：作为治疗剂代替ARYYYYOPENTEN
公开(公告)号：WO2008091810A1
公开(公告)日：2008-07-31
申请号：PCT/US2008/051540
申请日：2008-01-21
申请人： ALLERGAN, INC. , OLD, David, W. , NGO, Vinh, X.
发明人： OLD, David, W. , NGO, Vinh, X.
IPC分类号： C07C405/00 , C07D333/16 , A61K31/381
CPC分类号： C07D333/38 , C07C69/736 , C07C323/52 , C07C405/00 , C07C2601/08
摘要： Disclosed herein are compounds of the formula : Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
摘要翻译：本文公开了下式的化合物：还公开了与之相关的治疗方法，组合物和药物。

100. 发明申请

WO2008070479A2 METHOD FOR DETERMINING OPTIMUM INTRAOCULAR LOCATIONS FOR DRUG DELIVERY SYSTEMS 审中-公开
标题翻译：用于确定药物递送系统的最佳内部位置的方法
公开(公告)号：WO2008070479A2
公开(公告)日：2008-06-12
申请号：PCT/US2007/085626
申请日：2007-11-27
申请人： ALLERGAN, INC. , ROBINSON, Michael, R. , LIN, Joan-en, C. , WELTY, Devin, F. , WHITCUP, Scott, M. , HUGHES, Patrick, M.
发明人： ROBINSON, Michael, R. , LIN, Joan-en, C. , WELTY, Devin, F. , WHITCUP, Scott, M. , HUGHES, Patrick, M.
IPC分类号： A61F9/00
CPC分类号： A61K39/3955 , A61F9/0017 , A61K9/0048 , A61K31/573 , A61K31/58

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