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    • 9. 发明申请
    • ANTI-OBESITY DEVICES
    • 抗菌装置
    • WO2004087014A3
    • 2005-01-27
    • PCT/US2004009269
    • 2004-03-26
    • GI DYNAMICS INCLEVINE ANDY HCVINAR JOHN FMEADE JOHN C
    • LEVINE ANDY HCVINAR JOHN FMEADE JOHN C
    • A61F2/04A61F5/00
    • A61F5/0076
    • A restrictive device (216) implanted in the upper part of the stomach, selectively divides the stomach into two chambers (220, 222), effectively reducing the size of the stomach immediately available for the uptake of food. The restrictive device also includes an aperture (218), limiting the rate at which food can pass from the esophagus portion of the stomach into the intestine. Being removable, the device permits a physician to change the size of the opening in a minimally invasive manner by replacing a removable member with another member having an aperture of a different size and/or shape. The restrictive device can also be combined with an elongated tube (302), or sleeve to selectively bypass the stomach, a portion of the intestine, or a combination of bypassing both the stomach and a portion of the intestine, allowing a physician to endoscopically create an equivalent to the Roux-en-y weight loss procedure.
    • 植入胃的上部的限制性装置(216)选择性地将胃分成两个腔室(220,222),从而有效地减小了立即可用于摄取食物的胃的尺寸。 限制装置还包括孔(218),其限制食物可以从胃的食道部分进入肠的速度。 该装置可移动,允许医师通过用具有不同尺寸和/或形状的孔的另一构件替换可移除构件,以微创方式改变开口的尺寸。 限制性装置还可以与细长管(302)或套管组合以选择性地绕过胃,肠的一部分或绕过胃和肠的一部分的组合,允许医师内窥镜地产生 相当于Roux-en-y减肥程序。
    • 10. 发明申请
    • SLEEVE FOR DELAYED INTRODUCTION OF ENZYMES INTO THE INTESTINE
    • 将酶延迟引入INTESTINE的SLEEVE
    • WO2004087233A3
    • 2004-12-16
    • PCT/US2004009448
    • 2004-03-26
    • GI DYNAMICS INCLEVINE ANDY HMEADE JOHN C
    • LEVINE ANDY HMEADE JOHN C
    • A61F5/00A61M5/32A61F2/04
    • A61F5/0076
    • An elongated tube (122) is configured to carry digestive enzymes from the point at which they enter the duodenum, and deposit them downstream into a distal portion of the intestine, such as the distal jejunum, several feet down. This delays the breakdown and subsequent digestion of food. The proximal end of the tube can be secured to the hepatopancreatic ampulla, below the common bile duct using an anchor (260), such as a stent-like device. The tube can include an elongated flexible sleeve (122) coupled at its proximal end to an anchor. The anchor is attached to the hepatopancreatic ampulla and the sleeve is then draped distally, through the intestines. Natural peristalsis carries the enzymes through the tube distally. The enzymes then exit the tube and mix with the chyme further down stream than is normal.
    • 细长管(122)被配置为从进入十二指肠的点携带消化酶,并将它们下游沉积到肠的远端部分,例如几英尺的远端空肠。 这会延迟食物的分解和随后的消化。 管的近端可以使用诸如支架样装置的锚固件(260)固定到肝胰胆管下方的胆总管下方。 管可以包括在其近端处连接到锚的细长柔性套筒(122)。 锚固件连接到肝胰腺,并且套管然后通过肠部向远侧覆盖。 天然蠕动通过管向远端携带酶。 酶然后离开管并与正常进一步下游的食糜混合。