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    • 1. 发明申请
    • FUEL CELL
    • 燃料电池
    • WO0128023A3
    • 2001-12-27
    • PCT/DE0003263
    • 2000-09-20
    • INTECH THUERINGEN GMBHBRUDER MICHAELHEIBER UWEKRAUSE KARL HEINZMERKMANN GERHARD
    • BRUDER MICHAELHEIBER UWEKRAUSE KARL-HEINZMERKMANN GERHARD
    • C08J5/22H01M8/0293H01M8/1023H01M8/1051H01M8/1072H01M8/10
    • H01M8/1023C08J5/2231C08J2327/24H01M8/0293H01M8/1051H01M8/1072Y02P70/56
    • The invention relates to a fuel cell (1) comprising at least the following components: a proton-conducting polymer membrane (2) acting as the electrolyte, catalyst layers (3) that cover the polymer membrane (2) on both sides, gas-permeable electrodes in the form of an anode (4) and a cathode (5) which rest on a surface of the catalyst layers (3), whereby said surface is directed towards the outside, electroconductive plates (6) which contact the electrodes in an electroconductive manner and at closely adjacent distances and, together with the electrodes, define gas-conducting channels as well as gas supplies for the supply of hydrogen (H2) on the one hand and oxygen (O2) on the other hand. The inventive fuel cell (1) is characterised in that the polymer membrane (2) is a vulcanised caoutchouc mixture on the basis of a halogenated caoutchouc, especially when bromobutyl caoutchouc is used. The invention also relates to advantageous variants of the polymer membrane (2), e.g. when the caoutchouc mixture contains a molecular sieve/acid adduct.
    • 本发明涉及一种燃料电池(1),其至少包含以下组分,即:作为电解质的质子传导性聚合物膜(2) 覆盖聚合物膜(2)两侧的催化剂层(3); (4)和阴极(5)形式的气体可渗透电极,所述阳极(4)和阴极(5)抵靠所述催化剂层(3)的面向外的表面; 导电板(6),其以紧密间隔的间隔导电接触电极并与电极一起限定气体携带通道; 和用于一方面提供氢气(H2)和另一方面提供氧气(O2)的气体连接。 根据本发明的燃料电池(1)的特征在于,聚合物膜(2)是基于卤化橡胶的硫化橡胶混合物,特别是使用溴化丁基橡胶。 此外,聚合物膜(2)的有利变型例如通过含有分子筛/酸加合物的橡胶混合物呈现。
    • 3. 发明申请
    • HYBRID MEMBRANE POLYMER ELECTROLYTE FUEL CELL
    • 复合式膜聚合物电解质燃料电池
    • WO02082562A3
    • 2003-06-26
    • PCT/DE0200648
    • 2002-02-22
    • INTECH THUERINGEN GMBHSCHMAUDER HANS-PETERSCHUNK WERNERBRUDER MICHAELHEIBER UWEKRAUSE KARL-HEINZMERKMANN GERHARD
    • SCHMAUDER HANS-PETERSCHUNK WERNERBRUDER MICHAELHEIBER UWEKRAUSE KARL-HEINZMERKMANN GERHARD
    • H01M8/10
    • H01M8/1016
    • The invention relates to a fuel cell (1) comprising at least the following parts: a proton-conducting membrane (2) serving as an electrolyte; catalyst layers (3), which cover the membrane (2) on both sides; gas permeable electrodes provided in the form an anode (4) and cathode (5), which rest on the outwardly pointing surface of the catalyst layers (3); electrically conductive plates (6), which contact the electrodes in an electrically conductive manner while being located at small distances from one another, and which, together with the electrodes, delimit gas-conducting channels, and; gas connections for supplying hydrogen (H2) on one side and oxygen (O2) on the other. The inventive fuel cell (1) is characterized in that the membrane (2) is a hybrid membrane comprising a matrix into which a channel-forming protein is mixed. The invention also relates to advantageous variants of the membrane (2) in which the matrix, for example, contains a molecular sieve/protein adduct.
    • 本发明涉及一种燃料电池1,包括至少以下部件:质子导电膜2作为电解质,催化剂层3上的膜2覆盖气体可渗透电极的两侧的阳极4和阴极5,其抵靠所述催化剂层3的面向外的表面的形式进行电 导电板6,其导电地接触在紧密间隔的时间间隔的电极和与电极,和氢H¿2的供给气体连接一起限定气体传导频道? 一方面和氧O¿2其他。 本发明的燃料电池1的特征在于,该膜2是包括在其中的通道形成蛋白掺合基质的混合膜。 膜片2的另外的有利的变体中,例如,所述基质包含分子筛/蛋白质加合物。
    • 5. 发明申请
    • MATERIAL FOR PRODUCING PRODUCTS HAVING FIBRINOLYTIC AND/OR ANTIBACTERIAL PROPERTIES
    • 材料对产品的纤维蛋白溶解和/或抗菌特性上的制造
    • WO0230388A3
    • 2003-01-09
    • PCT/DE0103587
    • 2001-09-19
    • INTECH THUERINGEN GMBHSCHUNK WERNERBRUDER MICHAELGIESSMANN KONRADKRAUSE KARL-HEINZMERKMANN GERHARD
    • SCHUNK WERNERBRUDER MICHAELGIESSMANN KONRADKRAUSE KARL-HEINZMERKMANN GERHARD
    • A61K9/00A61K9/14A61M1/14A01N25/00B01D53/02B01D71/00B01J20/20
    • A61K9/0024A61K9/143
    • The invention relates to a material for producing products (1) having fibrinolytic and/or antibacterial properties. Said material has at least one matrix (2), which is compatible with body tissue and in which a molecular sieve is incorporated. Said molecular sieve is loaded with: at least one active substance (Z) having a fibrinolytic or antibacterial effect; or at least one first active substance (Z1) having a fibrinolytic effect and a second active substance (Z2) having an antibacterial effect. The corresponding molecular sieve/active substance adduct (3) releases the active substance(s) in conjunction with the aqueous body fluid when the matrix (2) is in contact with the body tissue (4). The inventive material is characterized in that the molecular sieve/active substance adduct (3) additionally contains water of crystallization to such an extent that the molecular sieve is partially dehydrated with regard to a sufficient basic molar quantity (m) of water of crystallization. The molecular sieve is loaded with the reduced molar quantity (m') of water of crystallization with the active substance(s) (Z, Z1, Z2) so that an adsorption of water with the desorption of the corresponding active substance occurs when the matrix (2) is in contact with the body tissue (4), whereby the water of crystallization of the molecular sieve increases. The invention also relates to an advantageous method for producing the inventive active substance.
    • 本发明涉及一种材料,所生产的产品(1)纤维蛋白溶解和/或抗菌性能,其包括至少一个身体组织相容性基质(2)到其中的分子筛是混合的,所述至少一种活性物质(Z)与血纤维蛋白溶解或抗菌作用或 至少一种第一活性成分(Z1),其具有纤维蛋白溶解活性和第二剂(Z2)装载有抗菌作用,其中相应的分子筛/活性物质在与身体组织(4)结合基质(2)的接触加合物(3) 水性体液/释放药物/秒。 本发明的材料现在的特征在于,所述分子筛/活性物质的加合物(3)还含有结晶水,并使得相对于结晶水的足够碱性的摩尔量(M),所述分子筛是部分脱水的方法,其中所述分子筛包含 减少摩尔量(M“)被加载在结晶水与/活性成分/ s的(Z,Z1,Z2),这样,在由相应的活性成分staffindet解吸的矩阵(2)与身体组织(4)的水吸附的接触 其中的分子筛增加结晶水含量。 此外,提出了一种用于生产本发明材料的有利方法。
    • 6. 发明申请
    • METHOD FOR HANDLING DATA MESSAGES IN A COMMUNICATIONS SYSTEM, AN APPROPRIATE COMMUNICATIONS SYSTEM AND SUBSCRIBERS THEREOF
    • 过程处理数据报文的通信系统,相关的通信系统,具有同等参与者
    • WO2005029786A2
    • 2005-03-31
    • PCT/EP2004009443
    • 2004-08-24
    • SIEMENS AGKRAUSE KARL-HEINZ
    • KRAUSE KARL-HEINZ
    • H04L12/433H04L12/46H04L12/56
    • H04L12/4637H04L12/433
    • The invention relates to a method for handling data messages in a communications system, an appropriate communications system and to the subscribers thereof. During a redundant data message exchange of the in a hierarchical ring system, a multiplication message problem always occurs for transmitting a data message from a first ring to a second ring. Said problem prevented until now the permanent redundant data message transmission through said hierarchical ring systems. In order to solve the problem, each subscriber handles a redundant data message which is received for transmission according to a set of rules implemented therein. Said rule set consists in splitting the original data message, transmitting it in the system and in destroying circulating data messages. For this purpose in order to implement said rule set, the subscriber is provided with a storage unit for storing the subscriber addresses, a marking is associated exactly with each storage unit and a second marking is associated exactly with each subscriber address.
    • 本发明涉及的处理在通信系统相关联的通信系统的数据消息,并且相同的用户的方法。 当数据的冗余交换的数据电报从第一环的第二环的过渡期间在分层环系统电报电报乘法的问题总是发生。 这种迄今防止这种分级环系永久冗余数据消息交换。 本发明解决了此问题,通过每个参与者根据实现在其设置的规则处理所接收的冗余来发送的数据报文。 这组规则涉及到一个主数据消息的分裂,其在系统中传输,和循环数据报文的破坏。 参与者被设计成它具有存储器装置,用于存储站地址,每个存储装置,标签被分配给精确地对一组规则的执行效果,并且每个站的地址与一个第二标记被分配。
    • 7. 发明申请
    • METHOD FOR ACCESSING A COMMAND UNIT FOR A DATA NETWORK
    • 用于访问数据网络的命令单元的方法
    • WO03028337A3
    • 2003-08-07
    • PCT/DE0203444
    • 2002-09-13
    • SIEMENS AGBRUECKNER DIETERGOETZ FRANZ-JOSEFKLOTZ DIETERKRAUSE KARL-HEINZSCHIMMER JUERGEN
    • BRUECKNER DIETERGOETZ FRANZ-JOSEFKLOTZ DIETERKRAUSE KARL-HEINZSCHIMMER JUERGEN
    • H04L12/40H04L29/06
    • H04L12/40H04L12/40019
    • The invention relates to a method and a user (100) of a data network (102) comprising: a command unit (116) for accessing the data network (102), means for operating several applications (104, 106, 108,...), whereby said applications can access a data bus (110) of the user (100), means for writing at least one command structure (118) in an address range of a memory of the user (100) by means of a first of the applications via the data bus (110), means for writing an indicator (124) for the address range in the input register (126) of the command unit (116) by means of the first application via the data bus (110), means for enabling the command unit (116) to access the address range via the data bus (110) and to process the command structure (118) and means for writing the indicator (124) in an output register (136, 130) that is assigned to the first application, once the user (100) has processed the command structure (118).
    • 本发明涉及一种方法和具有指示部(116)用于访问日期网络(102)的装置,用于操作多个应用程序(104,106,108,...)的数据网络(102)的订户(100),其中,所述 应用程序可以访问的用户(100)的数据总线(110)的装置,用于由第一通过数据总线(110)的应用程序中的用户(100)的存储器的地址区域中写入至少一个命令结构(118)的装置,用于写 指针(124)到在命令单元(116)通过经由所述数据总线(110)中的第一应用的输入寄存器(126)的地址区的装置,用于由指令单元(116)访问数据总线的地址区(110)和处理 所述命令结构(118)用于在所述订户(100)处理所述命令结构(118)之后将所述指针(124)写入与所述第一应用相关联的输出寄存器(136,130)的装置。
    • 8. 发明申请
    • MEANS AND METHODS FOR THE TREATMENT OF CATARACT AND PRESBYOPIA
    • 用于治疗感染和预后的手段和方法
    • WO2009044294A2
    • 2009-04-09
    • PCT/IB2008003602
    • 2008-06-12
    • UNIV GENEVEHOPITAUX UNIVERSITAIRES DE GENKRAUSE KARL-HEINZSERRANDER LENA
    • KRAUSE KARL-HEINZSERRANDER LENA
    • C12N9/02A61K31/713A61P27/10A61P27/12C12N15/11C12Q1/26
    • C12N9/0036A61K38/005
    • The present invention relates to an inhibitor of a protein, wherein said protein (i) comprises or consists of the amino acid sequence of SEQ ID NOs: 2 or 4, or is encoded by a nucleic acid comprising or consisting of the sequence of SEQ ID NOs: 1 or 3; (ii) comprises or consists of the amino acid sequence of SEQ ID NO: 26, or is encoded by a nucleic acid comprising or consisting of the sequence of SEQ ID NO: 25; (iii) is a fragment of the protein according to (i), or has a sequence at least 75% identical with the protein according to (i) or with said fragment of the protein according to (i), and exhibits NADPH oxidase activity; or (iv) is a fragment of the protein according to (ii) or has a sequence at least 75% identical with the protein according to (ii) or with said fragment of the protein according to (ii) and stabilizes said protein exhibiting NADPH oxidase activity; and/or an inhibitor of a nucleic acid, wherein said nucleic (v) comprises or consists of the nucleic acid sequence of SEQ ID NO: 1 or 3, or encodes a protein comprising or consisting of the sequence of SEQ ID NO: 2 or 4; (vi) comprises or consists of the nucleic acid sequence of SEQ ID NO: 25, or encodes a protein comprising or consisting of the sequence of SEQ ID NO: 26; (vii) is a fragment of the nucleic acid according to (v), or has a sequence at least 75% identical with the nucleic acid according to (v) or with said fragment of the nucleic acid according to (v), and encodes a protein exhibiting NADPH oxidase activity; or (viii) is a fragment of the nucleic acid according to (vi), or has a sequence at least 75% identical with the nucleic acid according to (vi) or with said fragment of the nucleic acid according to (vi), and encodes a protein stabilizing said protein exhibiting NADPH oxidase activity; for treatment and/or prevention of cataract and/or presbyopia. The sequences define NADPH oxidases or a subunit of an NADPH oxidase, respectively. A preferred inhibitor is a siRNA. Also provided are a method of treating cataract and presbyopia, pharmaceutical compositions, medical uses and diagnostic uses of compounds of the invention.
    • 本发明涉及蛋白质的抑制剂,其中所述蛋白质(i)包含SEQ ID NO:2或4的氨基酸序列或由SEQ ID NO:2或4的氨基酸序列组成,或由包含SEQ ID NO: NO:1或3; (ii)包含SEQ ID NO:26的氨基酸序列或由SEQ ID NO:26的氨基酸序列组成,或由包含或由SEQ ID NO:25的序列组成的核酸编码; (iii)是根据(i)的蛋白质的片段,或具有与根据(i)的蛋白质或根据(i)的蛋白质的所述片段至少75%相同的序列,并且表现出NADPH氧化酶活性 ; 或(iv)是根据(ii)的蛋白质的片段或具有与根据(ii)的蛋白质或根据(ii)的蛋白质的所述片段至少75%相同的序列,并稳定所述表达NADPH的蛋白质 氧化酶活性; 和/或核酸的抑制剂,其中所述核酸(v)包含SEQ ID NO:1或3的核酸序列或由SEQ ID NO:1或3的核酸序列组成,或编码包含SEQ ID NO:2或SEQ ID NO:2的序列或由SEQ ID NO: 4; (vi)包含SEQ ID NO:25的核酸序列或由SEQ ID NO:25的核酸序列组成,或编码包含SEQ ID NO:26的序列或由SEQ ID NO:26的序列组成的蛋白质。 (vii)是根据(v)的核酸的片段,或具有与根据(v)的核酸或根据(v)的核酸的所述片段至少75%相同的序列,并编码 表现出NADPH氧化酶活性的蛋白质; 或(viii)是根据(vi)的核酸的片段,或具有与根据(vi)的核酸或根据(vi)的核酸的所述片段至少75%相同的序列,和 编码稳定表达NADPH氧化酶活性的所述蛋白质的蛋白质; 用于治疗和/或预防白内障和/或老花眼。 序列分别定义NADPH氧化酶或NADPH氧化酶的亚基。 优选的抑制剂是siRNA。 还提供了治疗本发明化合物的白内障和老花眼的方法,药物组合物,医学用途和诊断用途。
    • 10. 发明申请
    • METHOD FOR OPERATING AN END-USER OF AN ISOCHRONOUS CYCLICAL COMMUNICATION SYSTEM
    • 用于操作订户的同步周期性通信系统
    • WO03036832A3
    • 2003-08-21
    • PCT/DE0203752
    • 2002-10-04
    • SIEMENS AGKLOTZ DIETERBRUECKNER DIETERKRAUSE KARL-HEINZ
    • KLOTZ DIETERBRUECKNER DIETERKRAUSE KARL-HEINZ
    • H04J3/06H04L12/64
    • H04J3/0652H04J3/0682H04J3/0694H04L2012/6454H04L2012/6462
    • The invention relates to a method for operating an end-user (306) of an isochronous cyclical communication system (300), comprising the following steps: receipt of a synchronisation data telegramme (510) from a connecting user (303) in the communication system (300) by the end-user (306), whereby the synchronisation data telegramme is affected by the run time (T, T1, T2) of a transmission run between the connecting user and the end-user, synchronisation of a time base of the end-user (306) by means of the synchronisation data telegramme, resulting in a synchronisation of the time base with a tolerance corresponding to the run time, cyclical processing of a transmission list by the end user (306) within a communication cycle (500, 502) corresponding to the time base of the end user, whereby the transmission of a data telegramme (700) occurs according to the transmission list from the end user to the connecting user at the earliest at the beginning of the communication cycle (500, 502) and at the latest at a point equivalent to the tolerance (T) before the projected transfer time point of the relevant data telegramme by the communication user (303).
    • 本发明涉及一种方法,用于操作的最终用户(306)同步一个,环状通信系统(300),包括以下步骤:由最终用户(306)接收来自所述通信系统(300)的连接的用户(303)的同步数据电报(510),其中,所述 同步数据与电报的渡越时间(T,T1,T2)相关联的连接的用户和最终用户之间的传输链路; 端部(306)与同步数据电报的辅助下的时间的基础上,产生具有对应于该术语的结果的容差的时基的同步的同步; 对应于所述端部的时间的基础上,通过一个通信周期(500,502)内的最终用户(306)发送列表的循环处理,其中,根据从终端用户在最早的连接的用户在通信周期的开始的发送列表中的数据报文(700)的传输(500,502 ),并在有关的数据报文的转发配置时间(TW)之前最新由公差(T)由连接的用户(303)发生。