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    • 5. 发明授权
    • DNA marking of previously undistinguished items for traceability
    • 以前不可区分的物品的DNA标记可追溯性
    • US09266370B2
    • 2016-02-23
    • US14584100
    • 2014-12-29
    • APDN (B.V.I.) Inc.
    • Lawrence JungJames A. HaywardMingHwa Benjamin LiangAbdelkrim Berrada
    • G09F3/00B41M3/14G07D7/14B42D25/378
    • B41F17/00B41M3/14B42D25/378B42D25/405C12Q1/68G07D7/14Y10T29/49826Y10T29/49885
    • The invention provides a method of marking an item with naturally-derived or synthetic non-natural polymeric marker molecules, such as a DNA or Peptide marker in conjunction with optional visible or rapid scan reporters for authenticating or tracking, in which the method includes providing an item for marking, and applying a medium including a DNA marker to the item. The invention further provides methods for stably binding and immobilizing activated deoxyribonucleic acid onto objects and substrates. The method includes exposing the deoxyribonucleic acid to alkaline conditions, and contacting the deoxyribonucleic acid to the object or substrate. Also provided are methods for increasing the recoverability of taggants from an object. The methods include the steps of incorporating a taggant into a solution; mixing the solution including the taggant with a perturbant to form a first perturbant taggant solution; mixing the first perturbant taggant solution with a polymer to form a second perturbant taggant polymer solution; and applying the second perturbant taggant polymer solution to at least a portion of the object to form a taggant-coated object. The invention also provides a method of marking an item with a DNA marker for authenticating or tracking, in which the method includes providing a medium including a DNA marker, and molding the medium including the DNA marker to provide all or part of the item. The DNA marker encodes information unique to the item and/or the model of the item as desired.
    • 本发明提供了一种使用天然衍生或合成的非天然聚合物标记分子(例如DNA或肽标记)与用于鉴定或跟踪的可选的可见或快速扫描记录器一起标记物品的方法,其中所述方法包括提供 用于标记的项目,以及将包括DNA标记的培养基应用于该物品。 本发明还提供了将活化的脱氧核糖核酸稳定结合并固定在物体和底物上的方法。 该方法包括将脱氧核糖核酸暴露于碱性条件下,并使脱氧核糖核酸与对象或底物接触。 还提供了用于增加标签从对象的可恢复性的方法。 所述方法包括将标签剂掺入溶液中的步骤; 将包含标签剂的溶液与扰动剂混合以形成第一扰动标记剂溶液; 将第一扰动标记剂溶液与聚合物混合以形成第二扰动标记聚合物溶液; 以及将所述第二扰动标记聚合物溶液施加到所述物体的至少一部分以形成标记剂涂覆物体。 本发明还提供了用用于鉴定或追踪的DNA标记物标记物品的方法,其中所述方法包括提供包含DNA标记物的培养基,并且模制包含DNA标记的培养基以提供该物品的全部或部分。 DNA标记根据需要编码项目和/或项目模型唯一的信息。
    • 7. 发明授权
    • Method and composition of matter for detecting large quantities of paper
currency
    • 用于检测大量纸币的物质的方法和组成
    • US5057268A
    • 1991-10-15
    • US629994
    • 1990-12-19
    • Richard A. Muller
    • Richard A. Muller
    • D21H21/48G01N23/221G07D7/06G07D7/14
    • G01N23/221D21H21/48G07D7/06G07D7/14
    • Paper notes used as a monetary currency are deuterated. The level of deuteration while not complete, is high. For U.S. currency the level of deuteration is at least 0.1 mg of deuterium for each one dollar in value of the currency note, and preferably at least 0.3 mg. Use of X-ray or gamma ray interrogation with a beam energy above 2 MeV produces a nuclear reaction releasing a neutron from the deuterium nucleus. If the currency is in large concentrations, e.g. $100,000 or more, the neutrons emitted by this reaction are reliably detectable. The deuteration occurs in the cellulose fibers forming the currency. To resist an exchange of hydrogen atoms for deterium atoms, the deuterium atoms can be used in the formation of synthetic cellulose where the deuterium is more deeply buried within the cellulose molecule than in naturally occurring cellulose. The deuterated synthetic fibers are blended with natural, non-deuterated fibers to form the paper. The currency can also include a mechanism, such as dye, to signal attempts to use solvents or otherwise facilitate any such hydrogen substitution.
    • 用作货币的纸币是氘化的。 氘代水平不完全高。 对于美国货币,贬值水平对于货币价值的每一美元至少为0.1毫克氘,优选至少为0.3毫克。 使用X射线或γ射线询问,光束能量高于2 MeV会产生从氘核释放中子的核反应。 如果货币是大量的,例如 10万美元以上,这种反应发射的中子是可靠的检测。 在形成货币的纤维素纤维中发生氘化。 为了阻止氢原子交换用于腐蚀原子,氘原子可用于合成纤维素的形成,其中氘比纤维素中天然纤维素分子更深地埋在其中。 氘代合成纤维与天然的非氘化纤维混合形成纸。 该货币还可以包括诸如染料之类的机制来表明尝试使用溶剂或以其他方式促进任何这种氢取代。