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1. 发明申请

US20210208082A1 METHOD, APPARATUS AND SYSTEM FOR DETECTING AND DETERMINING COMPROMISED REAGENT PADS BY QUANTIFYING COLOR CHANGES INDUCED BY EXPOSURE TO A HOSTILE ENVIRONMENT 有权
公开(公告)号：US20210208082A1
公开(公告)日：2021-07-08
申请号：US17206399
申请日：2021-03-19
申请人： HEALTHY.IO LTD.
发明人： Bernard Burg , Martin Zizi , Walter De Brouwer , Jaime Tenedorio , Babak Aghazadeh , Jie Cui , Sheena Menezes
IPC分类号： G01N21/84 , G01N21/79 , G01N21/81 , G01N33/52 , G06T7/90 , G01N21/80 , G01N21/78
摘要： A reagent test paddle includes a contamination detection medium, a reference color bar, at least one chemical test medium, and a unique identifier. The contamination detection medium includes a reagent that changes color in the presence or when exposed to a hostile or inhospitable environment. Each chemical test medium includes a regent that is responsive to a respective analyte in a biological sample. The reference color bar includes reference color samples of different colors. The unique identifier, like a serial number, identifies the particular paddle and its chemical test medium so it can be uniquely and anonymously associated with a user. A method includes capturing and interpreting digital images of a biologically unexposed and subsequently exposed reagent test paddle at various delay times within an automatically calibrated environment; locating the paddle in a plurality of digital images, extracting the reference color bar and locating the contamination detection medium and chemical test medium in each digital image. Color changes of the chemical test medium and contamination medium are detected at various delay times after sample exposure. To determine validity of test results, the method further compares the detected colors of the contamination detection medium with predetermined colors expected for no contamination and contamination.

2. 发明申请

US20200225166A1 METHOD, APPARATUS AND SYSTEM FOR DETECTING AND DETERMINING COMPROMISED REAGENT PADS BY QUANTIFYING COLOR CHANGES INDUCED BY EXPOSURE TO A HOSTILE ENVIRONMENT 审中-公开
公开(公告)号：US20200225166A1
公开(公告)日：2020-07-16
申请号：US16246406
申请日：2019-01-11
申请人： SCANADU INCORPORATED
发明人： Bernard Burg , Martin Zizi , Walter De Brouwer , Jaime Tenedorio , Babak Aghazadeh , Jie Cui , Sheena Menezes
IPC分类号： G01N21/84 , G01N21/79 , G01N21/81 , G01N21/80 , G01N33/52 , G06T7/90
摘要： A reagent test paddle includes a contamination detection medium, a reference color bar, at least one chemical test medium, and a unique identifier. The contamination detection medium includes a reagent that changes color in the presence or when exposed to a hostile or inhospitable environment. Each chemical test medium includes a regent that is responsive to a respective analyte in a biological sample. The reference color bar includes reference color samples of different colors. The unique identifier, like a serial number, identifies the particular paddle and its chemical test medium so it can be uniquely and anonymously associated with a user. A method includes capturing and interpreting digital images of a biologically unexposed and subsequently exposed reagent test paddle at various delay times within an automatically calibrated environment; locating the paddle in a plurality of digital images, extracting the reference color bar and locating the contamination detection medium and chemical test medium in each digital image. Color changes of the chemical test medium and contamination medium are detected at various delay times after sample exposure. To determine validity of test results, the method further compares the detected colors of the contamination detection medium with predetermined colors expected for no contamination and contamination.

3. 发明授权

US10126246B2 Lab-on-a-chip for alkalinity analysis 有权
公开(公告)号：US10126246B2
公开(公告)日：2018-11-13
申请号：US14918178
申请日：2015-10-20
申请人： Hach Company
发明人： Corey Alan Salzer , Vishnu Vardhanan Rajasekharan , Isabel Nicola Huenig , Rainer Froemel , Markus Lenhard , Rolf Dieter Uthemann , Aria Farjam
IPC分类号： G01N21/78 , G01N21/79 , G01N21/80 , G01N33/18 , G01N21/77
摘要： Described is a lab-on-a-chip device and a method of employing a lab-on-a-chip device for determining the concentration of species present in the water.

4. 发明授权

US09435745B2 Measuring the rate of release of metal ions 有权
标题翻译：测量金属离子的释放速率
公开(公告)号：US09435745B2
公开(公告)日：2016-09-06
申请号：US14580510
申请日：2014-12-23
申请人： Colgate-Palmolive Company
发明人： Stanislav Jaracz , Ravi Subramanyam , Michael Prencipe
IPC分类号： G01N21/78 , G01N33/20 , G01N21/79 , G01N21/77 , A61Q11/00
CPC分类号： G01N21/78 , A61K8/466 , A61K2800/45 , A61Q11/00 , G01N21/77 , G01N21/79 , G01N33/20
摘要： A method of measuring the relative rates of release of a target metal ion from two or more samples includes: (i) providing at least two aliquots of a solution including an indicator, the indicator having a color; (ii) dispersing a sample into each aliquot; and (iii) during step (ii), monitoring the color of the indicator in situ to determine the rates of release of the target metal ions from the samples relative to one another. Each sample includes at least one source of the target metal ion. The indicator contains zincon. The samples are oral care compositions selected from a toothpaste, a tooth gel, and a tooth powder. The target metal ion is selected from the stannous and zinc (II).
摘要翻译：测量来自两个或更多个样品的靶金属离子的相对释放速率的方法包括：（i）提供包含指示剂的溶液的至少两个等分试样，所述指示剂具有颜色; （ii）将样品分散到每个等分试样中; 和（iii）在步骤（ii）期间，在现场监测指示剂的颜色，以确定目标金属离子从样品相对于彼此的释放速率。每个样品包括至少一种目标金属离子源。指标包含zincon。样品是选自牙膏，牙胶和牙粉的口腔护理组合物。目标金属离子选自亚锡和锌（II）。

5. 发明申请

US20150037901A1 METHODS AND KITS FOR QUANTITATIVE DETERMINATION OF TOTAL ORGANIC ACID CONTENT IN A COOLANT 有权
标题翻译：用于定量测定冷却剂中总有机酸含量的方法和试剂盒
公开(公告)号：US20150037901A1
公开(公告)日：2015-02-05
申请号：US14469038
申请日：2014-08-26
申请人： Theodore B. Lynn , Timothy D. Lynn
发明人： Theodore B. Lynn , Timothy D. Lynn
IPC分类号： G01N21/79
CPC分类号： G01N21/79 , G01N31/16 , G01N31/221 , Y10T436/20 , Y10T436/200833 , Y10T436/201666
摘要： The invention relates to methods and kits for determining the total organic acid content in a coolant sample.
摘要翻译：本发明涉及用于测定冷却剂样品中总有机酸含量的方法和试剂盒。

6. 发明申请

US20130115704A1 SYSTEM AND METHOD FOR THE ANALYSIS OF BIODIESEL 有权
标题翻译：生物物理分析系统与方法
公开(公告)号：US20130115704A1
公开(公告)日：2013-05-09
申请号：US13665433
申请日：2012-10-31
申请人： DEXSIL CORPORATION
发明人： Theodore B. Lynn , Lawrence M. Sacramone
IPC分类号： G01N33/22 , B01L3/00 , G01N21/79
CPC分类号： G01N33/2829 , B82Y10/00 , B82Y30/00 , C10L1/026 , Y02E50/13 , Y02T50/678
摘要： Methods and devices are disclosed providing techniques for measuring the amount of biodiesel in a fuel sample. The methods may be used in the field without the use of laboratory equipment. The biodiesel in the sample is converted to the corresponding free acid which can be isolated and quantified to provide information regarding the amount of biodiesel in the original sample.
摘要翻译：公开了提供用于测量燃料样品中的生物柴油量的技术的方法和装置。这些方法可以在现场使用而不使用实验室设备。将样品中的生物柴油转化为相应的游离酸，可以分离和定量，以提供关于原始样品中生物柴油量的信息。

7. 发明申请

US20120264221A1 METHOD FOR QUALIFYING A NON-PARTICULATE ADSORBENT BY MEANS OF A SECONDARY REACTION 审中-公开
标题翻译：通过二次反应鉴定非特异性吸附剂的方法
公开(公告)号：US20120264221A1
公开(公告)日：2012-10-18
申请号：US13515679
申请日：2010-11-10
申请人： Wolfgang Demmer , Rene Faber , Hans-Heinrich Hoerl , Axel Thiefes
发明人： Wolfgang Demmer , Rene Faber , Hans-Heinrich Hoerl , Axel Thiefes
IPC分类号： G01N21/78 , G01N33/20 , G01N21/79 , G01N33/00
CPC分类号： B01D69/02 , B01D65/10 , B01D67/0093 , B01D2311/24 , G01N2015/086 , G01N2030/889 , Y10T436/16
摘要： The present invention relates to a method for the validation of a non-particulate adsorbent by secondary reaction and a kit for the validation of a non-particulate adsorbent by secondary reaction.
摘要翻译：本发明涉及通过二次反应验证非颗粒吸附剂的方法和用于通过二级反应验证非颗粒吸附剂的试剂盒。

8. 发明申请

US20080009071A1 Methods and devices for hybridization and binding assays using thermophoresis 有权
标题翻译：使用热泳法进行杂交和结合测定的方法和装置
公开(公告)号：US20080009071A1
公开(公告)日：2008-01-10
申请号：US11811279
申请日：2007-06-07
申请人： Michael Sogard
发明人： Michael Sogard
IPC分类号： G01N21/79 , G01N33/53
CPC分类号： B01L7/54 , B01L2300/0636 , B01L2300/0877 , B01L2300/1805 , B01L2300/1838 , C12Q1/6837
摘要： An apparatus and method for performing hybridization or binding assays under thermophoretic conditions is provided.
摘要翻译：提供了一种用于在热泳条件下进行杂交或结合测定的装置和方法。

9. 发明授权

US6096274A Analysis device 失效
标题翻译：分析装置
公开(公告)号：US6096274A
公开(公告)日：2000-08-01
申请号：US89667
申请日：1998-06-03
申请人： Robert Hoogendijk , Willem Boor
发明人： Robert Hoogendijk , Willem Boor
IPC分类号： G01N1/00 , G01N21/79
CPC分类号： G01N35/1097 , Y10T436/116664
摘要： The invention relates to an analysis device with a multi-way valve which is connected, via a pump line, to a bidirectional pump. A storage member for storing a sample fed to it and any auxiliary substances is accommodated in the pump line. The multi-way valve is connected, via two separate discharge lines, to an analysis vessel. The multi-way valve and the pump are controlled, with the aid of a microprocessor, in such a manner that the following steps are carried out:a. connecting a first feed line to the pump line via the multi-way valve, in order to feed sample to the storage member,b. using the pump to suck the sample into the storage member,c. connecting the pump line, via the multi-way valve, to a first discharge line which opens into the analysis vessel,d. feeding some of the sample present in the storage member to the analysis vessel via the pump and via the first discharge line,e. connecting the pump line to the flushing line via the multi-way valve,f. discharging sample which has remained in the storage member via the flushing line by feeding the reactant to the multi-way valve until the multi-way valve is full of reactant,g. connecting the pump line, via the multi-way valve, to a second discharge line which opens into the analysis vessel, andh. introducing the reactant into the analysis vessel via the second discharge line.
摘要翻译：本发明涉及一种具有多通阀的分析装置，其经由泵管线连接到双向泵。用于存储供给其的样品和任何辅助物质的存储构件容纳在泵管线中。多通阀通过两条独立的排放管线连接到分析容器。多路阀和泵借助于微处理器以如下方式进行控制：a。通过多路阀将第一供给管线连接到泵管线，以便将样品送入储存部件，b。使用泵将样品吸入存储构件，c。将泵管线通过多通阀连接到通向分析容器的第一排放管线，d。通过泵和经由第一排出管线将存储构件中存在的一些样品供给到分析容器，通过多路阀将泵管路连接到冲洗管路，f。 g。通过将反应物送入多路阀，直到多通阀充满反应物，排出已经通过冲洗线保留在存储构件中的样品。将泵管线通过多路阀连接到通向分析容器的第二排放管线，以及h。通过第二排出管将反应物引入分析容器。

10. 发明授权

US5898002A Method for removing ferric-ferrous oxides from a liquid 失效
标题翻译：从液体中除去三价铁的方法
公开(公告)号：US5898002A
公开(公告)日：1999-04-27
申请号：US916198
申请日：1997-08-22
申请人： Terence P. Small
发明人： Terence P. Small
IPC分类号： G01N17/00 , G01N31/22 , G01N21/79
CPC分类号： G01N17/006 , G01N31/22 , Y10T436/25125
摘要： A method for removing ferric-ferrous oxides from a liquid containing ferric-ferrous oxides and ferrous ions and to a method for determining the amount of ferrous ion in a liquid. The invention has particular utility for use in a method to accurately determine the corrosion rates of ferrometals in contact with aqueous liquids by filtering ferric-ferrous oxides from the aqueous liquid prior to determining the ferrous ion content of the aqueous liquid.
摘要翻译：一种从含有二氧化铁和亚铁离子的液体中除去三价铁的方法以及用于测定液态中亚铁离子量的方法。本发明特别适用于在确定含水液体的亚铁离子含量之前，通过从水性液体中过滤三价铁的氧化物来准确地确定与含水液体接触的铁素体的腐蚀速率的方法。

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