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1. 发明授权

US07501025B2 Process and apparatus for the conversion of biomass 失效
标题翻译：用于生物质转化的方法和装置
公开(公告)号：US07501025B2
公开(公告)日：2009-03-10
申请号：US11837156
申请日：2007-08-10
申请人： Robert Reurd C. Bakker , Jacob Hendrik O. Hazewinkel , Johannes Wouterus Van Groenestijn
发明人： Robert Reurd C. Bakker , Jacob Hendrik O. Hazewinkel , Johannes Wouterus Van Groenestijn
IPC分类号： C13K1/02 , B01J3/00 , B01D21/01 , B01D19/00 , B01D53/14 , B03D3/00 , C07G17/00 , C07H1/00 , C07H3/00
CPC分类号： D21C11/0007 , C12M21/04 , C12M23/20 , C12M25/18 , C12M29/24 , C12M41/26 , C12P2201/00 , C13K1/02 , D21C5/00 , Y02E50/17 , Y02E50/343
摘要： The invention is directed to a process for the conversion of cellulosic biomass, in particular lignocellulose-containing biomass into fermentable sugars. The invention is further directed to apparatus suitable for carrying out such processes. According to the invention biomass is converted into fermentable sugars by contacting in a reactor said biomass with an acid, while passing an inert gas stream capable of taking up water through said reactor, by which the pH in said reactor can be controlled.
摘要翻译：本发明涉及将纤维素生物质，特别是含木素纤维素的生物质转化成可发酵糖的方法。本发明进一步涉及适于执行这种方法的装置。根据本发明，生物质通过在反应器中与所述生物质与酸接触而转化成可发酵糖，同时通过能够吸收水通过所述反应器的惰性气流，由此可控制所述反应器中的pH。

2. 发明申请

US20080261291A1 Method of Obtaining Cyanogenic Glycoside and Related Glycosides, as Well as Genin and Sapogenins Derivatives of Plants of the Family Sapotaceae for the Preparation of Cosmetics and Dermatological Compositions 有权
标题翻译：获得氰基糖苷和相关糖苷的方法，以及用于制备化妆品和皮肤病学组合物的茜草科植物的根和皂苷元衍生物
公开(公告)号：US20080261291A1
公开(公告)日：2008-10-23
申请号：US11632961
申请日：2004-07-21
申请人： Luis De La Llata Romero
发明人： Luis De La Llata Romero
IPC分类号： C07G17/00 , C07H1/08
CPC分类号： A61K36/185 , A61K8/97 , A61Q5/00 , A61Q7/00 , A61Q19/00 , A61Q19/08
摘要： Procedure for the obtaining of genin and sapogenins extracts by enzymatic hydrolysis of kernels derived of the family Sapotaceae, genus Calocarpum, Chrysophyllum and Lucuma. The enzymes that catalyzes the hydrolysis are exogenous β-glucosidases, of vegetable or microbial origin. The process uses mainly diverse kernel (seeds removed of the endocarp) derived but can also use the cyanogenic glycoside, lucumin and the related similar glycosides directly. It is also object of protection the process for the obtaining of these glycosides, starting of those kernels derived and the usage of these in the obtaining of genin and sapogenins and its uses in cosmetic and dermatologic compositions. The genin and sapogenins extracts are the main products used with these basic similar aims. The obtained genin extract are used in topical compositions to promote the opening of the pore facilitating the epithelial penetration or it can be used as flavouring or scent agent in foods or in alternating similar uses like in perfumery. The obtained sapogenins extract are used in topical compositions as astringent, defoliant, to favour oily skin penetration, to promote the renovation of the skin, to combat the epithelial aging, the growth of the hair or slow its fallen. The effect of oily skin penetration is enhanced synergised with a lipidic phase of the same Sapotaceae family. Besides the sapogenins have bacteriostatic and fungistatic activity in the compositions, in its topical use or in diverse preparations.
摘要翻译：通过酶水解衍生自苜蓿科（Sapotaceae），Calocarpum，Chrysophyllum和Lucuma的籽粒获得基因和皂甙元提取物的方法。催化水解的酶是植物或微生物来源的外源性β-葡萄糖苷酶。该方法主要使用不同的核（内果皮除去的种子），但也可以直接使用氰基苷，紫苏素和相关的相似糖苷。也是保护获得这些糖苷的方法的目标，起源于这些衍生的那些核，以及它们在获得基因和皂苷元中的用途及其在化妆品和皮肤病学组合物中的用途。基因和皂甙元提取物是与这些基本类似目的一起使用的主要产品。获得的精子提取物用于局部组合物以促进促进上皮渗透的孔的开放，或者它可以用作食品中的调味剂或香味剂，或者用于类似于香料中的类似用途。获得的皂甙元提取物用于局部组合物作为收敛剂，脱脂剂，有利于油性皮肤渗透，促进皮肤的翻新，以抵抗上皮老化，毛发生长或减缓其下降。油性皮肤渗透的作用增强与同一苜蓿科的脂质相互作用。除了皂苷元在组合物，局部用途或不同制剂中具有抑菌和抑制活性。

3. 发明授权

US07375095B2 Sugar derivative 有权
标题翻译：糖衍生物
公开(公告)号：US07375095B2
公开(公告)日：2008-05-20
申请号：US10495975
申请日：2002-11-19
申请人： Kazuyuki Oku , Naoki Kudo , Shigeharu Fukuda
发明人： Kazuyuki Oku , Naoki Kudo , Shigeharu Fukuda
IPC分类号： A01N43/54 , A01N43/04 , A61K31/715 , C07G17/00 , C07H1/00
CPC分类号： C07H15/00 , C07H3/06 , C07H11/00 , C07H13/00
摘要： For extending the uses of a compound represented by Chemical formula 1, the object of the present invention is to provide a derivative of cyclic tetrasaccharide whose physicochemical properties are changed from those of cyclic tetrasaccaride, a composition comprising the same, and a process for producing the same. The present invention solves the above object by providing a derivative of cyclic tetrasaccharide, which is produced by the steps of reacting a compound represented by Chemical formula 1 with a reactive reagent and substituting one ore more hydroxyl groups with substituents except hydroxyl group and O-glycosyl group; a composition comprising the same; and a process for producing the derivative of cyclic tetrasaccharide.
摘要翻译：为了延长由化学式1表示的化合物的用途，本发明的目的是提供一种环状四糖的衍生物，其物理化学性质与环状四十八烷的化学性质，包含它的组合物和其制备方法相同。本发明通过提供环状四糖的衍生物来解决上述目的，其通过以下步骤制备：将化学式1表示的化合物与反应性试剂反应，并用一个以上的羟基取代除羟基以外的取代基，O-糖基组; 包含该组合物的组合物; 以及制备环状四糖衍生物的方法。

4. 发明授权

US07361754B2 Genetically purified gellan gum 有权
标题翻译：基因纯化的结冷胶
公开(公告)号：US07361754B2
公开(公告)日：2008-04-22
申请号：US11156953
申请日：2005-06-20
申请人： Joseph M. Cleary , Russell J. Coleman , Nancy E. Harding , Yamini N. Patel
发明人： Joseph M. Cleary , Russell J. Coleman , Nancy E. Harding , Yamini N. Patel
IPC分类号： C07G17/00 , C12N1/20 , C12N15/87 , C09K3/00 , A23C9/154 , A23C9/12
CPC分类号： C08L5/00 , A23C9/137 , A23C9/1544 , A23L29/272 , C08B37/006 , C12N9/16 , C12N9/2402 , C12N9/2405 , C12P19/04 , C12Y302/01031
摘要： Mutational inactivation of proteins involved in para-cresol production in certain milk products results in improved taste and odor. The undesirable para-cresol forms over time as a result of enzymes produced by the bacterium that produces gellan gum. Since the gellan is typically used in a relatively unpurified form, the enzymes are added to the milk along with the gellan. Inactivation of the enzymes is a genetic means of eliminating the enzymes without requiring any additional purification or processing.
摘要翻译：涉及某些乳制品中对甲酚生产的蛋白质的突变失活导致改善的味道和气味。作为由产生结冷胶的细菌产生的酶的结果，不期望的对甲酚随时间而形成。由于结冷胶通常以相对未纯化的形式使用，所以将酶与吉兰糖一起加入到牛奶中。酶的失活是消除酶的遗传手段，而不需要任何额外的纯化或加工。

5. 发明授权

US07294498B2 Glycosidase enzymes 有权
标题翻译：糖苷酶
公开(公告)号：US07294498B2
公开(公告)日：2007-11-13
申请号：US10121032
申请日：2002-04-09
申请人： Edward J. Bylina , Ronald V. Swanson , Eric J. Mathur , David E. Lam
发明人： Edward J. Bylina , Ronald V. Swanson , Eric J. Mathur , David E. Lam
IPC分类号： C12N9/42 , D06M17/00 , C07G17/00
CPC分类号： C12N9/2491 , C12N9/2402 , C12N9/2445 , C12N9/2454 , C12N9/2457 , C12N9/2465 , C12N9/2468 , C12N9/2494 , C12P19/02 , C12Y302/01021 , C12Y302/01022 , C12Y302/01023 , C12Y302/01025 , C12Y302/01041
摘要： A thermostable glycosidase enzymes derived from various Thermococcus, Staphylothermus and Pyrococcus organisms is disclosed. The enzymes are produced from native or recombinant host cells and can be utilized in the food processing industry, pharmaceutical industry and in the textile industry, detergent industry and in the baking industry.
摘要翻译：公开了衍生自各种热球菌属，葡萄球菌属和火球菌属的热稳定性糖苷酶。酶由天然或重组宿主细胞产生，可用于食品加工业，制药工业，纺织工业，洗涤剂行业和烘焙行业。

6. 发明授权

US07227019B2 Process for the preparation of rebeccamycin and analogs thereof 失效
标题翻译：雷贝霉素及其类似物的制备方法
公开(公告)号：US07227019B2
公开(公告)日：2007-06-05
申请号：US10489625
申请日：2002-09-13
申请人： Jianji Wang
发明人： Jianji Wang
IPC分类号： C07H19/00 , C07H19/22 , C07G17/00 , C07D487/00
CPC分类号： C07H19/23 , C07D487/14
摘要： The present invention relates to a method for making an indolopyrrolocarbazole of the general formula [I], where the method includes the step of reacting a bisindolylmaleimide compound with an oxidizing agent in the presence of an oxygen containing gas at a temperature and for a time sufficient to yield the indolopyrrolocarbazole compound of the general formula [I]. Methods of making rebeccamycin analogs using the indolopyrrolocarbazole compound are also provided
摘要翻译：本发明涉及制备通式[I]的吲哚并吡咯并咔唑的方法，其中该方法包括在含氧气体存在下，在足够的温度和时间下使双吲哚基马来酰亚胺化合物与氧化剂反应的步骤得到通式[I]的吲哚并吡咯并咔唑化合物。还提供了使用吲哚并吡咯咔唑化合物制备雷贝霉素类似物的方法

7. 发明授权

US07141411B2 Decaffeinating microorganism and process of bio-decaffeination of caffeine containing solutions 有权
标题翻译：脱咖啡因微生物和含咖啡因的溶液的生物脱咖啡因的过程
公开(公告)号：US07141411B2
公开(公告)日：2006-11-28
申请号：US10400311
申请日：2003-03-27
申请人： Munna Singh Thakur , Renu Sarath Babu Vegesna , Naikankatte Ganesh Karanth , Mandyam Chakravarathy Varadaraj
发明人： Munna Singh Thakur , Renu Sarath Babu Vegesna , Naikankatte Ganesh Karanth , Mandyam Chakravarathy Varadaraj
IPC分类号： C07G17/00 , C12P1/04
CPC分类号： C12R1/38 , A23F5/204
摘要： The present invention relates to a simple, safe, and efficient process for the complete bio-decaffeination of caffeine-containing solutions using fungus Pseudomonas alcaligenes CFR 1708, a method of isolating pseudomonas alcaligenes CFR 1708 useful for the bio-decaffeination of caffeine-containing solutions, a Pseudomonas alcaligenes strain of accession number CFR 1708, and a decaffeinated solution obtained by aforementioned process.
摘要翻译：本发明涉及使用真菌产碱假单胞菌CFR 1708完全生物脱咖啡因的简单，安全和有效的方法，该方法是用于分离含有咖啡因的溶液的生物脱咖啡因的产碱假单胞菌CFR 1708 ，登录号CFR 1708的产碱假单胞菌菌株和通过上述方法获得的脱咖啡因溶液。

8. 发明申请

US20060223730A1 Calcium supplements 审中-公开
公开(公告)号：US20060223730A1
公开(公告)日：2006-10-05
申请号：US11298165
申请日：2005-12-08
申请人： Dean Neuls , Marcos Neves
发明人： Dean Neuls , Marcos Neves
IPC分类号： C07G17/00 , C11D17/00
CPC分类号： A23L17/60 , A23L33/16
摘要： A composition comprising at least 5%, by weight, of calcium and at least 5%, by weight, of magnesium wherein the composition is derived from marine algae.

9. 发明申请

US20050281882A1 Matrix made of a polysaccharide modified under an electron beam with a functional organosilicon compound 审中-公开
标题翻译：由电子束与功能性有机硅化合物改性的多糖制成的基体
公开(公告)号：US20050281882A1
公开(公告)日：2005-12-22
申请号：US11066194
申请日：2005-02-25
申请人： Ian Harrison , Jean-Francois Sassi , Christian Priou
发明人： Ian Harrison , Jean-Francois Sassi , Christian Priou
IPC分类号： A61K9/14 , C07G99/00 , C08B3/22 , C08B11/00 , C08B11/20 , C08B15/05 , C08B37/00 , C08F251/00 , C08G77/42 , C08G81/00 , C07G17/00
CPC分类号： C08L83/04 , C08B3/22 , C08B7/00 , C08B11/20 , C08B15/05 , C08B37/0087 , C08B37/0096 , C08F251/00 , C08G77/14 , C08G77/18 , C08G77/20 , C08G77/24 , C08G77/38 , C08G77/42 , C08G77/70 , C08L1/12 , C08L1/284 , C08L1/286 , C08L3/02 , C08L5/00 , C08L83/00 , C08L2666/26
摘要： Water-soluble or water-dispersible matrix, made of a polysaccharide modified under an electron beam with an organosilicon compound chosen from organosilanes and/or polyorganosiloxanes having at least one functional group capable of reacting and/or interacting with said polysaccharide. Use of the matrix as stabilizing agent in the preparation of simple emulsions, in particular of the water-in-oil type, or multiple emulsions, in particular of the water-in-oil-in-water type.
摘要翻译：水溶性或水分散性基质，由电子束改性的多糖制成，其中有机硅化合物选自有机硅烷和/或具有至少一个能够与所述多糖反应和/或相互作用的官能团的聚有机硅氧烷。在制备简单乳液，特别是油包水型或多重乳液，特别是水包油包水型中，使用基质作为稳定剂。

10. 发明授权

US06887856B1 Protection from ionizing irradiation or chemotherapeutic drug damage by in vivo gene therapy 失效
标题翻译：通过体内基因治疗防止电离辐射或化疗药物损伤
公开(公告)号：US06887856B1
公开(公告)日：2005-05-03
申请号：US08907041
申请日：1997-08-06
申请人： Joel S. Greenberger
发明人： Joel S. Greenberger
IPC分类号： A61K38/17 , A61K38/44 , A61K38/45 , A61K48/00 , A01N43/04 , A01N63/00 , C07G17/00 , C12N15/00 , C12N15/63
CPC分类号： A61K48/00 , A61K38/1709 , A61K38/446 , A61K38/45
摘要： A method of protecting a subject against an agent that elicits production of toxic free radicals, superoxide anions, or heavy metal cations in the subject is disclosed which entails in vivo administration to the subject of a polynucleotide encoding a protein that is transiently expressed in said subject. The transiently expressed protein is capable of neutralizing or eliminating the toxic free radicals, superoxide anions or heavy metal cations that are elicited by the agent. The method is particularly useful in protecting cancer patients against the damaging effects of ionizing radiation and chemotherapeutic drugs. A composition useful in carrying out the method also is disclosed.
摘要翻译：公开了一种保护受试者免受在受试者中产生毒性自由基，超氧化物阴离子或重金属阳离子的药剂的方法，其需要向受试者体内施用编码在所述受试者中瞬时表达的蛋白质的多核苷酸。瞬时表达的蛋白质能够中和或消除由药剂引起的毒性自由基，超氧化物阴离子或重金属阳离子。该方法在保护癌症患者免受电离辐射和化学治疗药物的破坏作用方面特别有用。还公开了可用于实施该方法的组合物。

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