专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06790955B2 Processes for the preparation of aminophenylsulfonyl-ureas and intermediate products for the processes 有权
标题翻译：用于制备氨基苯磺酰脲和中间产物的方法
公开(公告)号：US06790955B2
公开(公告)日：2004-09-14
申请号：US10288052
申请日：2002-11-05
申请人： Gerhard Schnabel , Jan Vermehren , Lothar Willms
发明人： Gerhard Schnabel , Jan Vermehren , Lothar Willms
IPC分类号： C07D27300
CPC分类号： C07D521/00 , A01N47/36 , H01R33/06 , Y02A40/143
摘要： The invention relates to the preparation of compounds (I) in which A═H or acyl and R1, R2, R3, R, n, X, Y and Z are as defined in claim 1 by halogenation and rearrangement of compounds (II) (optionally salt) to give compounds (III) a) ammonolysis of (III) to (IV), reduction of the nitro group and reaction with carbamate (salts) (VI) of the formula Ar—OCO—N(M)-Het, where Ar=phenyl, M═H or cation and Het=heterocycle from formula (I), to give compounds (I) (A═H), or b) ammonolysis of (III) to (IV), reaction with carbamate (salt) (VI) and reduction of resulting compounds (VII) at the NO2 group to give compounds (I) (A═H), or c) reaction of (III) with cyanates and amines (VII) of the formula HNR3-Het and reduction of the resulting compound (VII) at the NO2 group to give compounds (I) (A═H) and optional acylation if A is to be other than H. Compounds of the formulae (I) (A═H), (III), (IV), (V), (VI) (M=cation) and (VII) are novel.
摘要翻译：本发明涉及其中A = H或酰基和R 1，R 2，R 3，R 3，n，X，Y和Z如权利要求1中所定义的化合物（I）的制备，化合物（II）（任选盐）的卤化和重排以得到化合物（III）a）（III）至（IV）的氨解，还原硝基并与式Ar-的氨基甲酸酯（盐）（Ⅵ）其中Ar =苯基，M = H或阳离子和Het =来自式（I）的杂环，得到化合物（I）（A = H），orb）氨解（III）至（III） IV），与氨基甲酸酯（盐）（VI）的反应和NO 2基团上得到的化合物（VII）的还原，得到化合物（I）（A = H），orc）（III）与氰酸酯和胺的反应（VII）的式（HNR 3）-Het，并且在NO 2基上还原所得化合物（Ⅶ），得到化合物（I）（A = H），并且如果A不为H，则为任意的酰化。式 I）（A = H），（III），（IV），（V），（VI）（M =阳离子）和（VII）

2. 发明授权

US06407233B1 Halogen pyrimidines and its use thereof as parasite abatement means 有权
标题翻译：卤素嘧啶及其作为减少寄生虫的手段
公开(公告)号：US06407233B1
公开(公告)日：2002-06-18
申请号：US09560021
申请日：2000-04-27
申请人： Ulrich Heinemann , Herbert Gayer , Peter Gerdes , Bernd-Wieland Krüger , Bernd Gallenkamp , Uwe Stelzer , Albrecht Marhold , Ralf Tiemann , Stefan Dutzmann , Gerd Hänssler , Klaus Stenzel
发明人： Ulrich Heinemann , Herbert Gayer , Peter Gerdes , Bernd-Wieland Krüger , Bernd Gallenkamp , Uwe Stelzer , Albrecht Marhold , Ralf Tiemann , Stefan Dutzmann , Gerd Hänssler , Klaus Stenzel
IPC分类号： C07D27300
CPC分类号： C07D273/00 , C07D413/12 , C07D413/14
摘要： Compounds of the formula (I) in which A represents optionally substituted alkanediyl, R represents in each case optionally substituted cycloalkyl, aryl or benzo-fused heterocyclyl, E represents —CH═ or nitrogen, Q represents oxyen, sulphur, —C2—O—, a single bond, or a nitrogen atom which is optionally substituted by alkyl, and X represents halogen.
摘要翻译：式（I）化合物，其中A表示任选取代的烷二基，R表示在各自情况下为任选取代的环烷基，芳基或苯并稠合的杂环基，E表示-CH =或氮，Q表示氧，硫，-C2-O-，单键或任选被烷基取代的氮原子，X表示卤素。

3. 发明授权

US06175007B1 Substituted aromatic phoshonic acid derivatives 失效
标题翻译：取代芳香族磷酸衍生物
公开(公告)号：US06175007B1
公开(公告)日：2001-01-16
申请号：US09117665
申请日：1998-08-04
申请人： Cyrill Zagar , Elisabeth Heistracher , Olaf Menke , Gerhard Hamprecht , Markus Menges , Peter Sch{umlaut over (a)}fer , Karl-Otto Westphalen , Ulf Misslitz , Helmut Walter
发明人： Cyrill Zagar , Elisabeth Heistracher , Olaf Menke , Gerhard Hamprecht , Markus Menges , Peter Sch{umlaut over (a)}fer , Karl-Otto Westphalen , Ulf Misslitz , Helmut Walter
IPC分类号： C07D27300
CPC分类号： C07F9/6561 , A01N57/24 , A01N57/32 , C07F9/4015 , C07F9/4056 , C07F9/5537 , C07F9/65031 , C07F9/65038 , C07F9/6506 , C07F9/650905 , C07F9/6512 , C07F9/6539 , C07F9/65583 , C07F9/65586
摘要： Phosphonic acid compounds I wherein Eth is optionally substituted 1,2-ethynediyl, ethanediyl or ethene-1,2-diyl; Y1 is oxygen or sulfur; Y2 is oxygen, sulfur or —N(R6)—; Y3 is oxygen, sulfur or —N(R7)—; R1, R2, R6 and R7 are hydrogen or optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, phenyl or heterocyclyl, or R1 and R2, R1 and R6, R2 and R7 together are optionally substituted 1,2-ethanediyl, 1,3-propylene, tetramethylene, pentamethylene or ethyleneoxyethylene, or R1 and R2 together are optionally substituted 1,2-phenylene; R3 is cyano, halogen, alkyl, haloalkyl, alkoxy or haloalkoxy; R4 is hydrogen or halogen, and R5 is a heterocycle &PHgr;1 to &PHgr;22 as defined in the specification, their manufacture and intermediates therefore. The phosphonic acid compounds are effective against unwanted plants and act as desiccants and defoliants.
摘要翻译：膦酸化合物Ⅰ其中任选被取代的1,2-亚乙炔基，乙二基或乙烯-1,2-二基; Y1是氧或硫; Y2是氧，硫或-N（R6） - ; Y3是氧，硫或-N （R 7） - ; R 1，R 2，R 6和R 7是氢或取代的烷基，烯基，炔基，环烷基，苯基或杂环基，或R 1和R 2，R 1和R 6，R 2和R 7一起是任选取代的1,2-乙二基，，3-亚丙基，四亚甲基，五亚甲基或亚乙基氧乙烯，或者R 1和R 2一起是任选取代的1,2-亚苯基; R 3是氰基，卤素，烷基，卤代烷基，烷氧基或卤代烷氧基; R 4是氢或卤素，R 5是杂环＆ 1至＆lt; PHgr 22，因此其制造和中间体。膦酸化合物对有害植物有效，作为干燥剂和脱叶剂。

4. 发明授权

US06600039B1 PROCESS FOR THE PREPARATION OF N-(1,1-DIMETHYLETHYL)-4-[[5′-ETHOXY-4-CIS[2-(4-MORPHOLINO)ETHOXY]-2′-OXOSPIRO[CYCLOHEXAN-1,3′[H]INDOL]1′(2′-H)-YL]-SULFONYL]-3-METHOXYBENZAMIDE AND ITS SALTS 失效
标题翻译：制备N-（1,1-二甲基乙基）-4 - [[5'-乙氧基-4- CIS [2-（4-吗啉基）乙氧基] -2'-氧代吡咯并[环己基] -1,3- H]吲哚] 1'（2'-H）-YL] - 磺基] -3-甲氧基苯甲酸及其盐
公开(公告)号：US06600039B1
公开(公告)日：2003-07-29
申请号：US10030647
申请日：2002-04-17
申请人： Gergely Héja , Éva Csikós , Tünde Erösné Takácsy , Csaba Gönczi , Judit Halász , István Hermecz , Csilla Majláth , Lajos Nagy , Andrea Sántáné Csutor , Péter Sárosi , Kálmán Simon , Tiborné Szomor , Györgyné Szvoboda
发明人： Gergely Héja , Éva Csikós , Tünde Erösné Takácsy , Csaba Gönczi , Judit Halász , István Hermecz , Csilla Majláth , Lajos Nagy , Andrea Sántáné Csutor , Péter Sárosi , Kálmán Simon , Tiborné Szomor , Györgyné Szvoboda
IPC分类号： C07D27300
CPC分类号： C07D209/96
摘要： The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reaction in dimethyl sulfoxide, at a temperature between 10° C. and 40° C., preferably at room temperature and transforming the resulting base of formula (I), if desired, into its salt by a method known per se.
摘要翻译：本发明涉及制备式（I）化合物及其盐的方法，其通过使式（II）化合物与式（III）化合物反应，其包括在二甲基亚砜中进行反应，温度在10℃至40℃之间，优选在室温下，如果需要，通过本身已知的方法将得到的式（I）碱转化成其盐。

5. 发明授权

US06355615B1 Desoxycyclodepsipeptides and their use for combatting endoparasites 失效
标题翻译：脱氧环肽和它们用于对抗内寄生虫的用途
公开(公告)号：US06355615B1
公开(公告)日：2002-03-12
申请号：US09424803
申请日：1999-11-29
申请人： Hubert Dyker , Jürgen Scherkenbeck , Achim Harder , Norbert Mencke , Georg von Samson-Himmelstjerna
发明人： Hubert Dyker , Jürgen Scherkenbeck , Achim Harder , Norbert Mencke , Georg von Samson-Himmelstjerna
IPC分类号： C07D27300
CPC分类号： C07D273/00 , C07D413/10 , C07D413/14
摘要： The invention relates to novel deoxycyclodepsipeptides which are prepared from cyclodepsipeptides having 24 ring members which are constructed from alternating &agr;-aminocarboxylic acids and &agr;-hydroxycarboxylic acids, by complete or partial chemoselective reduction of the carbonyl groups of the amide function to give methylene groups using suitable reduction processes, and to mixtures and derivatives thereof. The deoxycyclodepsipeptides according to the invention have anthelmintic activity.
摘要翻译：本发明涉及新的脱氧环肽，其由具有24个环成员的环缩缩肽制备，所述环成员由交替的α-氨基羧酸和α-羟基羧酸构成，通过完全或部分化学选择性还原酰胺官能团的羰基以使用合适的还原过程，以及其混合物和衍生物。根据本发明的脱氧环肽是具有驱虫活性的。

6. 发明授权

US06346603B1 Crystal of depsipeptide derivative and process for producing the same 有权
标题翻译：去三肽衍生物的晶体及其制备方法
公开(公告)号：US06346603B1
公开(公告)日：2002-02-12
申请号：US09530591
申请日：2000-05-08
申请人： Atsushi Yamamura , Ryo Yamanishi , Muneharu Ikushima
发明人： Atsushi Yamamura , Ryo Yamanishi , Muneharu Ikushima
IPC分类号： C07D27300
CPC分类号： C07D273/00
摘要： Crystals of a depsipeptide derivative of formula (IV): having an antiparasitic activity and methods for producing such crystals. Such crystals include crystals (I), (II) and (III) that have particular physicochemical properties or characteristics, such as excellent filtration properties during crystallization, great fluidity, good specific volume. As a consequence, such crystals have improved handling ability during production resulting in enhanced production efficiency and increased crystal yield. Methods are also provided for producing such crystals.
摘要翻译：式（IV）的去三肽衍生物的晶体：具有抗寄生虫活性及其制备方法。这种晶体包括具有特定物理化学性质或特性的结晶（I），（II）和（III），例如结晶时的优异过滤性能，流动性好，比容量大。结果，这种晶体在生产过程中具有改进的处理能力，从而提高生产效率和提高晶体产率。还提供了用于制备这种晶体的方法。

7. 发明授权

US06271226B1 Oxime derivatives and their use as fungicides 失效
标题翻译：肟衍生物及其作为杀真菌剂的用途
公开(公告)号：US06271226B1
公开(公告)日：2001-08-07
申请号：US09284367
申请日：1999-04-14
申请人： Bernd-Wieland Krüger , Peter Gerdes , Herbert Gayer , Ralf Tiemann , Stefan Dutzmann , Klaus Stenzel , Gerd Hänssler
发明人： Bernd-Wieland Krüger , Peter Gerdes , Herbert Gayer , Ralf Tiemann , Stefan Dutzmann , Klaus Stenzel , Gerd Hänssler
IPC分类号： C07D27300
CPC分类号： C07D273/00 , A01N43/88
摘要： The invention relates to novel oxime derivatives of formula (I), in which A stands for alkadiyl, Ar for optionally substituted aryls or heteroaryls respectively, G for a single bond, optionally an alkandiyl interrupted by heteroatoms (in which nonetheless the carbon atom is bound to R1, and is always bound to a carbon atom of the alkandiyl chain) or a grouping, R3—O—N═C═ wherein R3 stands for alkyl, R1 respectively for hydrogen, cyano or substituted alkyl, alkoxy, alkylthio, alkylamino or cycloalkyl, R2 stands for hydrogen or alkyl, Y stands for oxygen, sulfur or NH, and Z stands respectively for optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, aryl or heterocyclyl, to a method for their production and their use as fungicides, as well as to new intermediate products and multiple methods for their production.
摘要翻译：本发明涉及式（I）的新型肟衍生物，其中A分别表示任选取代的芳基或杂芳基，Ar表示烷酰基，Ar表示单键，G表示杂原子间隔的烷基，（其中碳原子结合 R3至ON = C =，其中R3代表烷基，R1分别表示氢，氰基或取代的烷基，烷氧基，烷硫基，烷基氨基或环烷基， R2代表氢或烷基，Y代表氧，硫或NH，Z代表任选取代的烷基，烯基，炔基，环烷基，芳基或杂环基，用于其生产方法及其作为杀真菌剂的用途，以及新的中间产品和多种生产方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式