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    • 4. 发明授权
    • Ether compounds
    • 醚化合物
    • US06459003B1
    • 2002-10-01
    • US09540738
    • 2000-03-31
    • Jean-Louis Henri DasseuxCarmen Daniela Oniciu
    • Jean-Louis Henri DasseuxCarmen Daniela Oniciu
    • C07C4302
    • C07D233/72C07C43/132C07C59/125C07C311/04C07F9/091Y10S514/866Y10S514/909
    • The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising an ether compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing Alzheimer's Disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.
    • 本发明涉及新型醚化合物,包含醚化合物的组合物和用于治疗和预防心血管疾病,血脂异常,dysproteinemias和葡萄糖代谢紊乱的方法,包括施用包含醚化合物的组合物。 本发明的化合物,组合物和方法还可用于治疗和预防阿尔茨海默病,综合征X,过氧化物酶体增殖物激活受体相关病症,败血症,血栓形成障碍,肥胖症,胰腺炎,高血压,肾脏疾病,癌症,炎症和 阳。 在某些实施方案中,本发明的化合物,组合物和方法可用于与其它治疗剂如降胆固醇和降血糖药物组合治疗。