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1. 发明申请

US20190031605A1 TETRAHYDRONAPHTHALENE DERIVATIVE 审中-公开
公开(公告)号：US20190031605A1
公开(公告)日：2019-01-31
申请号：US16073620
申请日：2017-01-27
申请人： ONO PHARMACEUTICAL CO., LTD.
发明人： Toshihide WATANABE , Kensuke KUSUMI , Yuichi INAGAKI
IPC分类号： C07D205/04 , C07D223/16 , C07D405/12 , C07D207/16 , C07C229/42 , C07C69/612 , C07C33/30 , C07C43/23 , C07C33/34 , C07C49/84 , C07C409/38 , C07D217/26 , C07D417/12 , C07D403/12
摘要： A compound represented by general formula (I-1): wherein the symbols are defined in the specification, has a selective S1P5 receptor binding activity and modulates the function of an S1P5 receptor, and can therefore be a therapeutic agent for a S1P5-mediated disease, for example, neurodegenerative diseases such as schizophrenia, Binswanger's disease and the like.

2. 发明授权

US5837782A Bis(mono-and-diperoxyoxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates 失效
标题翻译：衍生自二氢过氧化物和烷基和烷基过氧基草酸盐的双（一 - 和二过氧氧化物）
公开(公告)号：US5837782A
公开(公告)日：1998-11-17
申请号：US947533
申请日：1997-10-10
申请人： Jose Sanchez
发明人： Jose Sanchez
IPC分类号： C07C409/38 , C07C409/40 , C08F4/36 , C08F14/06 , C08F283/01 , C08F299/04 , C08F20/22 , C07C69/67 , C07C331/04 , C07G63/91
CPC分类号： C08F14/06 , C07C409/38 , C08F283/01 , C07C2101/14 , C07C2102/42
摘要： A novel bis(mono- or diperoxyoxalate) composition of Structure A, ##STR1## and use of the novel bis(mono- or diperoxyoxalate) composition as an initiators for curing of unsaturated polyester resins and for polymerizing ethylenically unsaturated monomers are disclosed.
摘要翻译：公开了一种新型的结构A（单或二过氧草酸）组合物，其中新型双（单 - 或二过氧草酸）组合物用作不饱和聚酯树脂的固化引发剂和烯键式不饱和单体的聚合。

3. 发明授权

US5644004A Multi-component ethylenically unsaturated peroxyesters 失效
标题翻译：多组分烯属不饱和过氧酯
公开(公告)号：US5644004A
公开(公告)日：1997-07-01
申请号：US378148
申请日：1995-01-25
申请人： Jose Sanchez
发明人： Jose Sanchez
IPC分类号： C07C409/00 , C07C409/38 , C08F2/46 , C08F2/48 , C08F4/38 , C08F299/04 , C08F20/00
CPC分类号： C08F299/045 , C07C409/38 , C08F4/38
摘要： A novel and safe ethylenically unsaturated peroxyester composition derived from an ethylenically unsaturated dicarboxylic acid is provided, as well as processes for making and using the composition. The peroxyester composition comprises about 0.04 to about 0.70 mole fraction of a first component compound having a formula I: ##STR1## about 0.32 to about 0.50 mole fraction of a second component compound having a formula II: ##STR2## about 0.04 to about 0.70 mole fraction of a third component compound having a formula III: ##STR3## wherein Q is an unsaturated ethylene divalent radical and R.sup.1 and R.sup.2 are organic substituents. Polymeric-peroxides are prepared via polymerizing the peroxyester compositions. The peroxyester compositions are also used for curing unsaturated polyester resins and for initiating polymerization of ethylenically unsaturated monomers.
摘要翻译：提供了一种由烯键式不饱和二羧酸衍生的新型和安全的烯属不饱和过氧酯组合物，以及制备和使用该组合物的方法。过氧酯组合物包含约0.04至约0.70摩尔分数的具有式I的第一组分化合物：具有式II的第二组分化合物的约0.32至约0.50摩尔分数：约0.04至约 0.70摩尔分数的具有式III的第三组分化合物：其中Q是不饱和乙烯二价基团，R 1和R 2是有机取代基。通过聚合过氧酯组合物制备聚合物 - 过氧化物。过氧酯组合物也用于固化不饱和聚酯树脂和用于引发烯属不饱和单体的聚合。

4. 发明授权

US5516856A Process for the use of antioxidant-peroxides to cure and enhance the stability of polymers 失效
标题翻译：使用抗氧化剂 - 过氧化物固化和提高聚合物稳定性的方法
公开(公告)号：US5516856A
公开(公告)日：1996-05-14
申请号：US375213
申请日：1995-01-18
申请人： Jose Sanchez
发明人： Jose Sanchez
IPC分类号： C09K15/08 , C07C67/00 , C07C407/00 , C07C409/16 , C07C409/34 , C07C409/38 , C07C409/40 , C07C409/42 , C07F9/09 , C08F4/28 , C08F4/32 , C08F4/34 , C08F299/04 , C08K5/00 , C08K5/14 , C08K5/16 , C08K5/22 , C08K5/25 , C08L23/16 , C08L67/06 , C09K15/24 , C08F20/10 , C08F4/36 , C08L9/00 , C08L23/26 , C08L27/22 , C08L33/06 , C08L33/18 , C08L43/00
CPC分类号： C08K5/14 , C07C409/16 , C07C409/34 , C07C409/38 , C07C409/40 , C07C409/42 , C07F9/091 , C08F299/045 , C08F4/32 , C08K5/005
摘要： The present invention relates to a novel antioxidant-peroxide compound of Structure A,(Y--[--R--OO--X).sub.x --An].sub.y Ain which the definitions of X, Y, R, An, x, and y are given in the Summary of the Invention section, for example, t-butyl peroxy-3-(3,5-di-t-butyl-4-hydroxyphenyl)propionate, processes for producing polymeric compositions of enhanced oxidative stability via initiation of polymerization of ethylenically unsaturated monomers, curing of elastomers and unsaturated polyester resins, modification of polypropylene and other polymers and copolymers, and crosslinking of olefin polymers and copolymers, and the resulting polymers having enhanced oxidative stability.
摘要翻译：本发明涉及结构A，（Y - [ - R-OO-X）x-An] yA的新型抗氧化剂 - 过氧化物化合物，其中给出X，Y，R，An，x和y的定义在本发明概述部分中，例如叔丁基过氧-3-（3,5-二叔丁基-4-羟基苯基）丙酸酯，通过引发烯键式聚合制备具有增强的氧化稳定性的聚合物组合物的方法不饱和单体，弹性体和不饱和聚酯树脂的固化，聚丙烯和其它聚合物和共聚物的改性，以及烯烃聚合物和共聚物的交联，以及所得聚合物具有增强的氧化稳定性。

5. 发明授权

US5489699A Unsaturated peroxide compositions, polymeric-peroxides derived therefrom and their uses 失效
标题翻译：不饱和过氧化物组合物，衍生自其的聚合物 - 过氧化物及其用途
公开(公告)号：US5489699A
公开(公告)日：1996-02-06
申请号：US452548
申请日：1995-05-25
申请人： Jose Sanchez , Leonard H. Palys , Daryl L. Stein , John S. Yormick
发明人： Jose Sanchez , Leonard H. Palys , Daryl L. Stein , John S. Yormick
IPC分类号： C07D317/30 , C07C409/16 , C07C409/20 , C07C409/22 , C07C409/38 , C07C409/40 , C07D317/72 , C07D319/06 , C07D323/00 , C08F4/28 , C08F4/34 , C08F4/36 , C07C409/00
CPC分类号： C07C409/40 , C07C409/16 , C07C409/20 , C07C409/22 , C07C409/38 , C08F4/36
摘要： Novel unsaturated peroxide compositions of Structure A,R--Q--X--R.sub.1 A[Where the R--Q-- grouping contains a polymerizable carbon-carbon double bond, --X-- is a direct bond or a connecting diradical and --R.sub.1 is a peroxide containing radical all as defined in the Summary of the Invention Section.], polymeric-peroxide compositions derived from them and their uses are disclosed.
摘要翻译：结构A，RQX-R1A的新型不饱和过氧化物组合物[其中RQ-分组含有可聚合的碳 - 碳双键，-X-是直接键或连接双基，-R1是全部如本发明摘要]公开了衍生自它们的聚合物 - 过氧化物组合物及其用途。

6. 发明授权

US5292914A Organic peroxide and use thereof 失效
标题翻译：有机过氧化物及其用途
公开(公告)号：US5292914A
公开(公告)日：1994-03-08
申请号：US84174
申请日：1993-07-01
申请人： Shuji Suyama , Tomoyuki Nakamura , Hiroyuki Nagai , Mieko Takei
发明人： Shuji Suyama , Tomoyuki Nakamura , Hiroyuki Nagai , Mieko Takei
IPC分类号： C07C409/38 , C08F4/28 , C08F4/36 , C08F8/00 , C08F8/04 , C08G67/00 , C07C69/96
CPC分类号： C07C409/38 , C08F4/36
摘要： An organic peroxide consisting of 1 to 30 repeating units represented by the formula ##STR1## wherein R stands for one group selected from the class consisting of ethylene, acetylene, cyclohexylene, and phenylene groups and one of 1 and m stands for an integer of at least 1 and 1+m stands for an integer in the range of from 6 to 220. Polymerization initiator for a vinyl monomer consisting of the organic peroxide mentioned above. A method for polymerizing a vinyl monomer by using the polymerization initiator mentioned above.
摘要翻译：由1〜30个以下式表示的重复单元构成的有机过氧化物，式中，R表示选自乙烯，乙炔，亚环己基和亚苯基中的1个基团，1个和m个至少为1的整数，1 + m表示6至220的整数。由上述有机过氧化物组成的乙烯基单体的聚合引发剂。通过使用上述聚合引发剂使乙烯基单体聚合的方法。

7. 发明授权

US5210164A Organic peroxide having a polymerization-regulating ability 失效
标题翻译：具有聚合调节能力的有机过氧化物
公开(公告)号：US5210164A
公开(公告)日：1993-05-11
申请号：US401244
申请日：1989-09-27
申请人： Takeshi Komai , Kazuo Matsuyama , Isao Honma
发明人： Takeshi Komai , Kazuo Matsuyama , Isao Honma
IPC分类号： C07C409/38
CPC分类号： C08F4/34 , C08F2/38
摘要： A novel peroxy aryl carbonate which has the both properties of polymerization-initiating and regulating abilities, can be used as a radical polymerization initiator to regulate the polymerization rate, the polymerization degree and molecular weight distribution of the polymer and the like, and therefore produce superior styrene resin and methyl methacrylate syrup.
摘要翻译：具有聚合引发和调节能力两者性质的新型过氧化芳基碳酸酯可用作自由基聚合引发剂以调节聚合物的聚合速率，聚合度和分子量分布等，因此产生优异的苯乙烯树脂和甲基丙烯酸甲酯糖浆。

8. 发明授权

US5051531A Antioxidant-peroxides 失效
标题翻译：抗氧化过氧化物
公开(公告)号：US5051531A
公开(公告)日：1991-09-24
申请号：US200340
申请日：1988-05-31
申请人： Jose Sanchez
发明人： Jose Sanchez
IPC分类号： C09K15/08 , C07C67/00 , C07C407/00 , C07C409/16 , C07C409/34 , C07C409/38 , C07C409/40 , C07C409/42 , C07F9/09 , C08F4/28 , C08F4/32 , C08F4/34 , C08F299/04 , C08K5/00 , C08K5/14 , C08K5/16 , C08K5/22 , C08K5/25 , C08L23/16 , C08L67/06 , C09K15/24
CPC分类号： C08K5/14 , C07C409/16 , C07C409/34 , C07C409/38 , C07C409/40 , C07C409/42 , C07F9/091 , C08F299/045 , C08F4/32 , C08K5/005
摘要： The present invention relates to a novel antioxidant-peroxide compound of Structure A,(Y--[R--OO--X).sub.x --An].sub.y Ain which the definitions of X, Y, R, An, x, and y are given in the Summary of the Invention section, for example, t-butyl peroxy-3-(3,5-di-t-butyl-4-hydroxypheneyl) propionate, processes for producing polymeric composition of enhanced oxidative stability via initiation of polymerization of ethylenically unsaturated monomers, curing of elastomers and unsaturated polyester resins, modification of polypropylene and other polymers and copolymers, and crosslinking of olefin polymers and copolymers, and the resulting polymers having enhanced oxidative stability.

9. 发明授权

US4970244A Photopolymerization initiator and method of photopolymerization by use of said initiator 失效
标题翻译：光聚合引发剂和使用所述引发剂的光聚合方法
公开(公告)号：US4970244A
公开(公告)日：1990-11-13
申请号：US740278
申请日：1985-06-03
申请人： Takeshi Komai , Mamoru Shimizu
发明人： Takeshi Komai , Mamoru Shimizu
IPC分类号： C08F2/00 , C07C67/00 , C07C407/00 , C07C409/38 , C08F2/50 , C08F4/36 , G03F7/028 , G03F7/031
CPC分类号： G03F7/031 , C07C409/38 , C08F2/50
摘要： Photopolymerization initiators of the general formula: ##STR1## wherein R.sub.1 and R.sub.1 ' independently stand for a tertiary alkyl group or a tertiary aralkyl group and R.sub.2 and R.sub.2 ' independently stand for a hydrogen atom, a tertiary alkoxy group, or a tertiary aralkyloxy group are disclosed. They are useful for effecting polymerization of radically polymerizable unsaturated compounds.

10. 发明授权

US4777191A Photopolymerization initiator and method of photopolymerization by use of said initiator 失效
标题翻译：光聚合引发剂和使用所述引发剂的光聚合方法
公开(公告)号：US4777191A
公开(公告)日：1988-10-11
申请号：US117920
申请日：1987-11-05
申请人： Takeshi Komai , Mamoru Shimizu
发明人： Takeshi Komai , Mamoru Shimizu
IPC分类号： C08F2/00 , C07C67/00 , C07C407/00 , C07C409/38 , C08F2/50 , C08F4/36 , G03F7/028 , G03F7/031 , C08F20/06 , C08F20/10
CPC分类号： G03F7/031 , C07C409/38 , C08F2/50
摘要： Photopolymerization initiators of the general formula: ##STR1## wherein R.sub.1 and R.sub.1 ' independently stand for a tertiary alkyl group or a tertiary aralkyl group and R.sub.2 and R.sub.2 ' independently stand for a hydrogen atom, a tertiary alkoxy group, or a tertiary aralkyloxy group are disclosed. They are useful for effecting polymerization of radically polymerizable unsaturated compounds. Tetra peroxy esters of benzophenone are preferred.
摘要翻译：其中R1和R1独立地代表叔烷基或叔芳烷基，R2和R2'独立地代表氢原子，叔烷氧基或叔芳烷氧基是通式为的光聚合引发剂：披露它们可用于实现自由基聚合的不饱和化合物的聚合。二苯甲酮的四过氧酯是优选的。

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