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1. 发明申请

US20160023998A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS 审中-公开
公开(公告)号：US20160023998A1
公开(公告)日：2016-01-28
申请号：US14876626
申请日：2015-10-06
申请人： Bezwada Biomedical, LLC
发明人： Rao S Bezwada
IPC分类号： C07C265/12 , C07C235/16 , C07C225/22 , C07C69/34
CPC分类号： C07C265/12 , A47F5/0006 , A61L17/00 , A61L17/105 , A61L17/12 , A61L17/145 , A61L24/06 , A61L27/18 , A61L27/34 , A61L27/52 , A61L27/58 , A61L31/10 , A61L31/145 , A61L31/148 , B65D25/22 , C07C69/34 , C07C69/67 , C07C69/708 , C07C205/37 , C07C205/43 , C07C205/57 , C07C217/84 , C07C219/34 , C07C225/22 , C07C229/18 , C07C229/60 , C07C235/16 , C08G63/16 , C08G63/916 , Y02W90/13 , Y10T24/44291 , Y10T24/51 , Y10T428/139 , Y10T442/10 , C08L67/04
摘要： The present invention relates to the discovery of new class of linear and multiarmed hydrolysable linkers and cross linkers for use in the synthesis of biodegradable polymers such as, polyesters, polyurethanes, polyamides, polyureas and degradable epoxy amine resin. The linear and multiarmed hydrolysable linkers of the present invention include symmetrical and/or unsymmetrical ether carboxylic acids, amines, amide diols, amine polyols and isocyanates.

2. 发明授权

US09101135B2 Agricultural/horticultural insecticide and method for using the same 有权
标题翻译：农/园艺杀虫剂及其使用方法
公开(公告)号：US09101135B2
公开(公告)日：2015-08-11
申请号：US14313131
申请日：2014-06-24
申请人： MITSUI CHEMICALS, INC.
发明人： Kei Yoshida , Takeo Wakita , Hiroyuki Katsuta , Akiyoshi Kai , Yutaka Chiba , Kiyoshi Takahashi , Hiroko Kato , Nobuyuki Kawahara , Michikazu Nomura , Hidenori Daido , Junji Maki , Shinichi Banba , Atsuko Kawahara
IPC分类号： C07C323/42 , C07C233/65 , A01N47/20 , C07C211/47 , C07C211/48 , C07C215/68 , C07C237/40 , C07C265/12 , C07C271/28 , C07C317/18 , C07C317/36 , C07C317/40 , C07C323/12 , C07C323/36 , C07C327/48 , C07C333/08 , C07D213/81
CPC分类号： A01N47/20 , C07C211/47 , C07C211/48 , C07C215/68 , C07C237/40 , C07C265/12 , C07C271/28 , C07C317/18 , C07C317/36 , C07C317/40 , C07C323/12 , C07C323/36 , C07C323/42 , C07C327/48 , C07C333/08 , C07C2601/04 , C07C2601/08 , C07D213/81
摘要： An object of the present invention is to provide insecticides having high effectiveness. The present invention provides compounds represented by formula (1): wherein A1, A2, A3, and A4 independently represent a carbon atom, a nitrogen atom, or an oxidized nitrogen atom; R1 represents a C1-C6 alkyl group which may be substituted, a phenyl group which may be substituted, or a heterocyclic group which may be substituted; R2 and R3 independently represent a hydrogen atom, a C1-C4 alkyl group which may be substituted, or a C1-C4 alkylcarbonyl group which may be substituted; G1, G2, and G3 independently represent an oxygen atom or a sulfur atom; Xs may be the same or different and each represent a hydrogen atom, a halogen atom, a C1-C4 alkyl group which may be substituted, or an amino group which may be substituted; n represents an integer of 0 to 4; Q represents a phenyl group which may be substituted, a naphthyl group which may be substituted, a tetrahydronaphthyl group which may be substituted, or a heterocyclic group which may be substituted, insecticides containing the compounds as active ingredients, and a method for producing the compounds. The compounds represented by formula (1) exhibit an excellent preventive effect as insecticides and also exhibit an excellent preventive effect when being combined with another insecticide, an acaricide, a nematocide, a fungicide, a herbicide, a plant growth regulator, or a biological pesticide.
摘要翻译：本发明的目的是提供具有高效率的杀虫剂。本发明提供由式（1）表示的化合物：其中A1，A2，A3和A4独立地表示碳原子，氮原子或氧化氮原子; R1表示可以被取代的C1-C6烷基，可被取代的苯基或可被取代的杂环基; R2和R3独立地表示氢原子，可被取代的C1-C4烷基或可被取代的C1-C4烷基羰基; G1，G2和G3独立地表示氧原子或硫原子; X可以相同或不同，各自表示氢原子，卤素原子，可被取代的C1-C4烷基或可被取代的氨基; n表示0〜4的整数， Q表示可被取代的苯基，可被取代的萘基，可被取代的四氢萘基或可被取代的杂环基，含有该化合物作为活性成分的杀虫剂，以及该化合物的制备方法。由式（1）表示的化合物作为杀虫剂显示出优异的预防作用，并且当与另一种杀虫剂，杀螨剂，杀线虫剂，杀真菌剂，除草剂，植物生长调节剂或生物农药组合时表现出优异的预防效果。

3. 发明申请

US20140142199A1 ABSORBABLE BRANCHED POLYESTERS AND POLYURETHANES 审中-公开
标题翻译：可吸收分散的聚酯和聚氨酯
公开(公告)号：US20140142199A1
公开(公告)日：2014-05-22
申请号：US14161026
申请日：2014-01-22
申请人： Bezwada Biomedical, LLC
发明人： Rao S. Bezwada
IPC分类号： C07C265/12 , C08G18/77
CPC分类号： C08G18/771 , A61L15/26 , A61L15/64 , A61L17/10 , A61L24/0042 , A61L24/046 , A61L26/0019 , A61L26/009 , A61L27/18 , A61L27/58 , A61L31/06 , A61L31/148 , C07C265/14 , C08G18/10 , C08G18/4277 , C08G18/4833 , C08G2230/00 , C08G18/3206 , C08L75/04
摘要： The present invention relates to the discovery of a new class of hydrolysable isocyanates, hydrolysable branched polyols and branched absorbable polyesters and polyurethanes prepared therefrom. The resultant absorbable polymers are useful for drug delivery, stents, highly porous foam, reticulated foam, tissue engineering, tissue adhesives, adhesion prevention, bone wax formulations, medical device coatings, surface modifying agents and other implantable medical devices. In addition, these absorbable polymers can have a controlled hydrolytic degradation profile.
摘要翻译：本发明涉及发现一类新的可水解异氰酸酯，可水解的支链多元醇和可分散的可吸收的聚酯和由其制备的聚氨酯。所得的可吸收聚合物可用于药物递送，支架，高度多孔泡沫，网状泡沫，组织工程，组织粘合剂，防粘连，骨蜡制剂，医疗装置涂层，表面改性剂和其它可植入医疗装置。此外，这些可吸收聚合物可以具有受控的水解降解曲线。

4. 发明授权

US08324292B2 Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant 有权
标题翻译：用作内部粘合剂或密封剂的二异氰酸酯封端的大分子单体的医学上可接受的制剂
公开(公告)号：US08324292B2
公开(公告)日：2012-12-04
申请号：US12040211
申请日：2008-02-29
申请人： Robert B. Vetrecin , Elizabeth Vailhe , Robert W. Van Holten
发明人： Robert B. Vetrecin , Elizabeth Vailhe , Robert W. Van Holten
IPC分类号： A61L24/04 , A61F2/00 , C08G18/70 , C08G18/72 , C08G18/77 , C07C265/12
CPC分类号： A61L24/0042 , A61L24/043 , C08G18/10 , C08G18/4252 , C08G2230/00 , C08L75/04 , C08L1/04 , C08G18/42
摘要： A medically acceptable formulation comprising a diisocyanate terminated macromer or mixture thereof, and an oxidized cellulose.
摘要翻译：包含二异氰酸酯封端的大分子单体或其混合物的医学上可接受的制剂和氧化纤维素。

5. 发明申请

US20120197037A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS 审中-公开
标题翻译：可水解连接器和可吸收聚合物的交联剂
公开(公告)号：US20120197037A1
公开(公告)日：2012-08-02
申请号：US13243537
申请日：2011-09-23
申请人： Rao S. Bezwada
发明人： Rao S. Bezwada
IPC分类号： C07C69/708 , C07C235/28 , C07C265/12 , C07C229/36 , C07C229/56 , C07C229/42
CPC分类号： C07C265/12 , A47F5/0006 , A61L17/00 , A61L17/105 , A61L17/12 , A61L17/145 , A61L24/06 , A61L27/18 , A61L27/34 , A61L27/52 , A61L27/58 , A61L31/10 , A61L31/145 , A61L31/148 , B65D25/22 , C07C69/34 , C07C69/67 , C07C69/708 , C07C205/37 , C07C205/43 , C07C205/57 , C07C217/84 , C07C219/34 , C07C225/22 , C07C229/18 , C07C229/60 , C07C235/16 , C08G63/16 , C08G63/916 , Y02W90/13 , Y10T24/44291 , Y10T24/51 , Y10T428/139 , Y10T442/10 , C08L67/04
摘要： The present invention relates to the discovery of new class of linear and multiarmed hydrolysable linkers and cross linkers for use in the synthesis of biodegradable polymers such as, polyesters, polyurethanes, polyamides, polyureas and degradable epoxy amine resin. The linear and multiarmed hydrolysable linkers of the present invention include symmetrical and/or unsymmetrical ether carboxylic acids, amines, amide diols, amine polyols and isocyanates.
摘要翻译：本发明涉及用于合成可生物降解聚合物如聚酯，聚氨酯，聚酰胺，聚脲和可降解环氧胺树脂的新类型的线性和多臂可水解连接体和交联剂的发现。本发明的线性和多臂可水解接头包括对称和/或不对称的醚羧酸，胺，酰胺二醇，胺多元醇和异氰酸酯。

6. 发明授权

US08232421B2 Bifunctional phenyl ISO (THIO) cyanates, processes and intermediates for their preparation 有权
标题翻译：双官能苯基ISO（THIO）氰酸酯，其制备方法和中间体
公开(公告)号：US08232421B2
公开(公告)日：2012-07-31
申请号：US12886986
申请日：2010-09-21
申请人： Gerhard Hamprecht , Michael Puhl , Bernd Wolf , Norbert Götz , Michael Keil , Robert Reinhard , Ingo Sagasser , Werner Seitz
发明人： Gerhard Hamprecht , Michael Puhl , Bernd Wolf , Norbert Götz , Michael Keil , Robert Reinhard , Ingo Sagasser , Werner Seitz
IPC分类号： C07C263/10 , C07C249/14 , C07C331/28 , C07C265/12 , C07D249/12
CPC分类号： C07D213/76 , C07C303/34 , C07C307/06 , C07C331/28 , C07C2601/14 , C07D207/20 , C07D211/18 , C07D211/70 , C07D295/26 , C07D307/52 , C07D319/06 , C07D333/20
摘要： A process for preparing phenyl iso(thio)cyanates of the formula I in which a compound of the formula II or its HCl adduct is reacted with a phosgenating agent where W is oxygen or sulfur and Ar and A are as defined in claim 1 is described. Moreover, the invention relates to the use of the phenyl iso(thio)cyanates for preparing crop protection agents.
摘要翻译：描述式I的苯基异（硫代）氰酸酯的方法，其中将式II化合物或其HCl加合物与W是氧或硫的光气反应剂和Ar和A如权利要求1中所定义的相同。此外，本发明涉及苯基异（硫代）氰酸酯用于制备作物保护剂的用途。

7. 发明申请

US20010041810A1 Process for preparing organic monoisocyanates 有权
标题翻译：制备有机单异氰酸酯的方法
公开(公告)号：US20010041810A1
公开(公告)日：2001-11-15
申请号：US09845873
申请日：2001-04-30
发明人： Martin Brahm , Lutz Schmalstieg , Ulrich Geron , Hans-Gunter Behr , Jorg Morawski
IPC分类号： C07C263/00 , C07C265/12
CPC分类号： C07C263/16 , C07C265/04
摘要： The present invention relates to a process for preparing a low boiling monoisocyanate having a boiling point of between 70 and 320null C. at standard pressure by reacting A) a high boiling isocyanate compound having a boiling point of at least 180null C. at standard pressure and an HC content of at least 50 ppm with B) a monoamine having a primary amino group, at a maximum reaction temperature of 180null C. and a molar ratio of isocyanate groups to amino groups of at least 4:1 to form a compound containing a biuret/urea group, simultaneously thermally decomposing this compound in situ to form a monoisocyanate corresponding to monoamine B) and removing the monoisocyanate by distillation, optionally under vacuum.
摘要翻译：本发明涉及一种在标准压力下制备沸点为70-320℃的低沸点单异氰酸酯的方法，该方法通过使A）沸点至少为180℃的高沸点异氰酸酯化合物与标准反应压力和HC含量至少为50ppm，B）具有伯氨基的单胺，最大反应温度为180℃，异氰酸酯基与氨基的摩尔比至少为4:1，形成含有缩二脲/脲基团的化合物，同时原位地分解该化合物以形成对应于单胺B的单异氰酸酯），并任选地在真空下通过蒸馏除去单异氰酸酯。

8. 发明授权

US6110870A N-cyanoaryl-nitrogen heterocycles 失效
标题翻译： N-氰基芳基 - 氮杂环
公开(公告)号：US6110870A
公开(公告)日：2000-08-29
申请号：US189361
申请日：1998-11-09
申请人： Roland Andree , Mark-Wilhelm Drewes , Albrecht Marhold , Hans-Joachim Santel , Markus Dollinger
发明人： Roland Andree , Mark-Wilhelm Drewes , Albrecht Marhold , Hans-Joachim Santel , Markus Dollinger
IPC分类号： A01N43/54 , C07C265/12 , C07C271/28 , C07C271/38 , C07C311/53 , C07D239/54 , C07D239/553 , C07D239/557 , C07D409/04 , C07D498/02
CPC分类号： C07D239/54 , A01N43/54 , C07C265/12 , C07C271/28 , C07C271/38 , C07C311/53 , C07D239/553
摘要： The invention relates to new N-cyanoaryl-nitrogen hetero-cycles of the general formula (I) ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and Z have the meanings given in the description,to a plurality of processes for their preparation, to their use as herbicides and to novel intermediates.
摘要翻译：本发明涉及通式（I）的新的N-氰基芳基氮杂环，其中R1，R2，R3，R4和Z具有说明书中给出的含义，其多个制备方法，用作除草剂和新型中间体。

9. 发明授权

US5847134A Fluorocarbon-containing isocyanate derivatives and soil-resist agents 失效
标题翻译：含氟碳的异氰酸酯衍生物和抗污剂
公开(公告)号：US5847134A
公开(公告)日：1998-12-08
申请号：US585339
申请日：1996-01-11
申请人： Donald Douglas May
发明人： Donald Douglas May
IPC分类号： C07C263/16 , C07C265/12 , C07C273/18 , C07C275/62 , C07D251/34 , C08G18/08 , C08G18/81 , C09D5/02 , C09D5/16 , C09D175/04 , D06M13/02 , D06M13/322 , D06M13/398 , D06M15/576 , C07D251/32 , C07C273/02 , C08G18/10
CPC分类号： C08G18/8166 , C07C275/62 , C07D251/34 , C08G18/0804 , D06M13/398 , D06M15/576
摘要： Products prepared by reacting polyisocyanates with alkenyl or alkynyl compounds; then with perfluoroalkyl iodides & dehydroiodinating the product.
摘要翻译：通过使多异氰酸酯与烯基或炔基化合物反应制得的产物; 然后用全氟烷基碘化物和脱氢碘化产物。

10. 发明授权

US5654474A Aromatic diisocyanate and method of producing the same 失效
标题翻译：芳族二异氰酸酯及其制备方法
公开(公告)号：US5654474A
公开(公告)日：1997-08-05
申请号：US723878
申请日：1996-09-23
申请人： Michie Ishii , Amane Mochizuki
发明人： Michie Ishii , Amane Mochizuki
IPC分类号： C07C265/12 , C08G18/77 , C07C263/04
CPC分类号： C07C265/12
摘要： Novel aromatic diisocyanate and a method of producing the same. The method comprises reacting a diamine compound with a chloroformate to produce an urethane intermediate, and then reacting the urethane intermediate with a halogenated organosilicon compound or a halogenated organoboron compound, using an organic solvent capable of dissolving both the diamine compound and the urethane intermediate. This method enables to produce the aromatic diisocyanate by one-pot. The aromatic diisocyanate has excellent various properties such as high heat resistance and chemical resistance.
摘要翻译：新型芳族二异氰酸酯及其制备方法。该方法包括使二胺化合物与氯甲酸酯反应以制备氨基甲酸酯中间体，然后使用能够溶解二胺化合物和氨基甲酸酯中间体的有机溶剂，使氨基甲酸酯中间体与卤代有机硅化合物或卤代有机硼化合物反应。该方法能够通过一锅生产芳族二异氰酸酯。芳族二异氰酸酯具有优异的各种性能，例如耐高温性和耐化学性。

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