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1. 发明申请

US20040054251A1 Corporal implantation device for assisting blood and heart ventricular circulation 失效
标题翻译：用于辅助血液和心脏心室循环的下体植入装置
公开(公告)号：US20040054251A1
公开(公告)日：2004-03-18
申请号：US10319244
申请日：2002-12-13
发明人： Domingo Santo Liotta
IPC分类号： A61M001/12
CPC分类号： A61M1/1037 , A61M1/1008 , A61M1/106 , A61M1/1098 , A61M1/12 , A61M1/122
摘要： A dual pusher-plate blood pump implanted into the body with either mechanical or biological valves (17) for unidirectional blood circulation through a circulation variable chamber (blood chamber) (12) to assist circulation. LVAS comprises a receptacle (housing) (4) provided with an inlet (3) and an outlet (5) The pump inflow (3) is connected to the left atrium and the pump outflow to the descending thoracic aorta (5,7) and a pulsating external pneumatic unit (8).
摘要翻译：用机械或生物瓣膜（17）将身体内的双推板血泵通过循环变量室（血液腔）（12）进行单向血液循环，以辅助循环。 LVAS包括设置有入口（3）和出口（5）的容器（壳体）（4）。泵入口（3）连接到左心房并且泵流出到下行胸主动脉（5,7）和脉动式外部气动单元（8）。

2. 发明申请

US20020198436A1 Circulation assist method and device utilizing balloon of IABP system and blood stream control valve therefor 审中-公开
标题翻译：循环辅助方法和装置利用IABP系统气球和血流控制阀
公开(公告)号：US20020198436A1
公开(公告)日：2002-12-26
申请号：US09942656
申请日：2001-08-31
发明人： Motoaki Hoshino
IPC分类号： A61M001/12
CPC分类号： A61M1/1096 , A61M1/1037 , A61M1/106 , A61M1/107 , A61M1/1072 , A61M1/1086 , A61M1/122 , A61M1/125 , A61M2205/33 , A61M2205/3303
摘要： A circulation assist method and device is provided wherein the contraction and expansion of a balloon of an IABP system which has already been widespread as a device for pressure support are utilized as power source for operating a pump so as to realize the assist of stream volume. A cylindrical pump chamber is connected at one and the other ends thereof respectively with an inflow hole and an outflow hole. An inflow valve is provided at the side of the inflow hole for permitting blood to stream from the inflow hole into the pump chamber but preventing the backward stream, and an outflow valve is further provided at the side of the outflow hole for permitting blood to stream from the pump chamber into the outflow hole but preventing the backward stream. A balloon portion of a balloon catheter connected to the IABP system is fluid-tightly incorporated into the pump chamber and is pulsated, so that blood is sucked into the pump chamber through the inflow valve when the balloon is contracted, and is ejected therefrom through the outflow valve when the balloon is expanded.
摘要翻译：提供了一种循环辅助方法和装置，其中已经广泛用作压力支持装置的IABP系统的气囊的收缩和膨胀被用作操作泵的动力源，以实现流量的辅助。圆柱形泵室的一端和另一端分别连接有流入孔和流出孔。流入阀设置在流入孔的侧面，用于允许血液从流入孔流入泵室，但是防止反向流动，并且在流出孔侧还设有流出阀，以允许血液流动从泵室进入流出孔，但是防止反向流动。连接到IABP系统的气囊导管的球囊部分被流体密封地结合到泵室中并被脉动，使得当气囊收缩时，血液通过流入阀被吸入泵室，并且通过气球膨胀时出流阀。

3. 发明申请

US20020161274A1 Methods, systems and devices relating to implantable fluid pumps 有权
标题翻译：与可植入流体泵有关的方法，系统和装置
公开(公告)号：US20020161274A1
公开(公告)日：2002-10-31
申请号：US09844446
申请日：2001-04-27
发明人： Ronald French , Bernard H. Andreas , Hanson S. Gifford III
IPC分类号： A61M001/12
CPC分类号： A61M1/1031 , A61M1/1008 , A61M1/101 , A61M1/122 , A61M1/127 , A61M2205/8243
摘要： An implantable pump system including an external driver. The implantable pump is driven by the external driver during normal operation but may also operate on a battery. The external driver is used to drive the pump with the mechanical energy of the impeller also being used to charge the battery. The external driver is also useful during emergency situations to directly drive the pump if the battery or internal coils should fail. The pump is also preferably implanted in a subpectoral location outside the patient's rib cage.
摘要翻译：一种包括外部驱动器的可植入泵系统。在正常操作期间，可植入泵由外部驱动器驱动，但也可以在电池上操作。外部驱动器用于驱动泵，其叶轮的机械能也用于对电池充电。如果电池或内部线圈故障，外部驱动器在紧急情况下也可以直接驱动泵。泵还优选地植入患者肋骨外部的子部位。

4. 发明申请

US20010037048A1 Combined catheter system for IABP and determination of thermodilution cardiac output 失效
标题翻译：用于IABP的组合导管系统和热稀释心输出量的测定
公开(公告)号：US20010037048A1
公开(公告)日：2001-11-01
申请号：US09834905
申请日：2001-05-24
发明人： Ulrich J. Pfeiffer , Steve Allen , Ulf Borg
IPC分类号： A61M001/12
CPC分类号： A61B5/028 , A61B5/029 , A61M1/1008 , A61M1/106 , A61M1/1072 , A61M1/1086 , A61M1/125 , A61M2025/0003 , A61M2205/33 , A61M2205/3303 , A61M2205/3334 , A61M2205/3368
摘要： An intro-aortic balloon catheter system and method for determining cardiac output with the system including a distal end for insertion into an aorta and a proximal end opposed to the distal end, a balloon portion in proximity to the distal end which repeatedly expands and contracts so as to assist the pumping action of the heart, a catheter tube connected to the balloon portion with the catheter tube having a lumen introducing a pressurized gas into the balloon portion and leading the pressurized gas out from the balloon portion and a temperature sensor attached to the catheter tube and being electrically coupled to a connector at the proximal end of the catheter tube. The method includes inserting the temperature sensor into a lumen of the intra aortic balloon catheter system, advancing the temperature sensor until it projects freely into the aorta, injecting an injectate of a temperature different to that of the temperature of the patient's blood into the central vein of the patient, measuring the blood temperature profile versus time by means of the temperature sensor and calculating cardiac output and optionally the derived variables from the measured temperature profile.
摘要翻译：一种主动脉内气囊导管系统和方法，用于利用所述系统确定心输出量，所述系统包括用于插入主动脉的远端和与所述远端相对的近端，邻近所述远端的气囊部分反复膨胀和收缩为了辅助心脏的泵送动作，导管与血管部分连接，其中导管管具有将加压气体引入球囊部分并将加压气体从球囊部分引出并将温度传感器附接到导管管并且电耦合到导管管的近端处的连接器。该方法包括将温度传感器插入主动脉内主动脉球囊导管系统的内腔，推进温度传感器直到其自由伸入主动脉，将与患者血液温度不同的温度注射入中央静脉的患者，通过温度传感器测量血液温度分布与时间的关系，并根据测量的温度曲线计算心输出量和可选的导出变量。

5. 发明申请

US20040152944A1 Chronic performance control system for rotodynamic blood pumps 有权
标题翻译：用于旋转动力血泵的慢性性能控制系统
公开(公告)号：US20040152944A1
公开(公告)日：2004-08-05
申请号：US10333759
申请日：2004-04-01
发明人： Alexander Medvedev , Leonard A R Golding , Alexander Massiello
IPC分类号： A61M001/12
CPC分类号： A61M1/101 , A61M1/1086 , A61M1/122 , A61M2205/3334 , A61M2205/3365
摘要： In a left ventricular assist device (LVAD) a rotodynamic blood pump (10) is powered by a brushless DC motor (12). A power supply (14) supplies power to the motor (12). Three feedback channels, one for each of voltage, current, and motor speed lead to a microcontroller or microprocessor (18). The three feedback waveforms are analyzed, and from these waveforms, motor input power, patient heart rate, current pump flow rate, and systemic pressure are determined. The microprocessor (18) then calculates a desired flow rate proportional to the patient heart rate. The microprocessor communicates a new power output to a commutation circuit (16), which regulates power to the mortor (12). The pump (10) also includes safety checks that are prioritized over desired pump flow. These include prevention of ventricular suction, low pulsatility, minimum and maximum pump speed, minimum peed-relative pump flow, minimum absolute pump flow, minimum and maximum motor input power.
摘要翻译：在左心室辅助装置（LVAD）中，旋转动力血泵（10）由无刷DC马达（12）供电。电源（14）向马达（12）供电。三个反馈通道，一个用于每个电压，电流和电机速度，导致微控制器或微处理器（18）。分析三个反馈波形，并从这些波形中确定电机输入功率，患者心率，电流泵流量和全身压力。微处理器（18）然后计算与患者心率成比例的期望流率。微处理器将新的功率输出传送到换向电路（16），该换向电路调节对榫体（12）的电力。泵（10）还包括优先于所需泵流量的安全检查。这些包括预防心室抽吸，低搏动，最小和最大泵速，最小相对泵流量，最小绝对泵流量，最小和最大电机输入功率。

6. 发明申请

US20020116055A1 Artificial heart with arrhythmia signalling 审中-公开
公开(公告)号：US20020116055A1
公开(公告)日：2002-08-22
申请号：US10113757
申请日：2002-03-29
申请人： The Penn State Research Foundation
发明人： Alan Snyder
IPC分类号： A61M001/12
CPC分类号： A61M1/1046 , A61M1/1005 , A61M1/1037 , A61M1/1051 , A61M1/1067 , A61M1/1086 , A61M1/12 , A61M1/122
摘要： An artificial heart assembly may be provided with a blood inlet conduit adapted to be implanted within a subject, a blood outlet conduit adapted to be implanted within the subject, a pumping mechanism implanted within the subject that pumps blood from the blood inlet conduit to the blood outlet conduit, and a motor coupled to drive the pumping mechanism. The artificial heart apparatus has a power source and a control circuit operatively coupled to cause the motor to drive the pumping mechanism in a regular mode when the power source has a relatively high charge level and in an irregular mode when the power source has a relatively low charge level so that the subject can feel when the pumping mechanism is being driven in the irregular mode and thus know that the power source has the relatively low charge level.

7. 发明申请

US20020095210A1 Heart pump graft connector and system 审中-公开
标题翻译：心脏泵移植连接器和系统
公开(公告)号：US20020095210A1
公开(公告)日：2002-07-18
申请号：US09761367
申请日：2001-01-16
发明人： Michael T. Finnegan , Long S. Yu
IPC分类号： A61M001/12
CPC分类号： A61M1/10 , A61F2/064 , A61M1/1008 , A61M1/101 , A61M1/12 , A61M1/122
摘要： A connector for connecting a blood processing device to vascular tissue includes a vascular tissue connecting element that is suturable to a portion of the cardiovascular system for providing a flow connection. A junction ring is affixed to the vascular tissue connecting portion in order to form a substantially shape retaining connecting element. A locking ring for locking the junction ring to a blood processing device includes a coupling element configured to engage a port on the blood processing device so that rotation of the locking ring draws the junction ring to the port and locks the junction ring into a sealing relationship with the port. The locking ring is freely rotatable about the junction ring so that the locking ring can be rotated to lock the junction ring to the port without twisting the vascular tissue connecting element.
摘要翻译：用于将血液处理装置连接到血管组织的连接器包括血管组织连接元件，其可连接到心血管系统的一部分以提供流动连接。接合环固定在血管组织连接部分上，以便形成基本形状的保持连接元件。用于将结环锁定到血液处理装置的锁定环包括配置成接合血液处理装置上的端口的联接元件，使得锁定环的旋转将接合环拉出到端口并将结环锁定成密封关系与港口。锁定环可以绕连接环自由旋转，使得锁定环可以旋转以将接合环锁定到端口，而不会扭转血管组织连接元件。

8. 发明申请

US20020019666A1 Circular artificial heart 失效
标题翻译：圆形人造心脏
公开(公告)号：US20020019666A1
公开(公告)日：2002-02-14
申请号：US09909614
申请日：2001-07-20
发明人： Izaak A. Ulert , Meinrich Lang
IPC分类号： A61M001/12
CPC分类号： A61M1/1081 , A61M1/1055 , A61M1/12
摘要： An artificial heart device for minimizing the damage to blood cells having electromagnetically driven pistons which move the blood around and through a toroidal chamber. In first and second preferred embodiments no motor is used to drive the pistons and the pistons are suspended within the toroid by cycling of electromagnets. In a third preferred embodiment the pistons are moved with the use of motor-driven magnets. In each embodiment blood is sucked into the toroidal chamber through one or more intake openings and blood exits the toroidal chamber through one or more outflow openings.
摘要翻译：一种人造心脏装置，用于使具有电磁驱动活塞的血细胞的损伤最小化，所述活塞将血液移动并穿过环形室。在第一和第二优选实施例中，没有电动机驱动活塞，并且活塞通过电磁铁的循环而悬挂在环形线圈内。在第三优选实施例中，使用电动机驱动的磁体来移动活塞。在每个实施例中，血液通过一个或多个进气口被吸入环形室，血液通过一个或多个流出开口离开环形室。

9. 发明申请

US20010039369A1 Blood pump system 审中-公开
标题翻译：血液泵系统
公开(公告)号：US20010039369A1
公开(公告)日：2001-11-08
申请号：US09776429
申请日：2001-02-02
发明人： Alexandre N. Terentiev
IPC分类号： A61M001/12
CPC分类号： F04D29/048 , A61M1/10 , A61M1/101 , A61M1/1015 , A61M1/1036 , A61M1/122 , A61M1/127 , B01F13/0818 , B01F2015/061 , F04D13/027 , F16C32/0438 , F16C37/005 , F16C2316/18
摘要： The present invention is directed to a blood pumping system that includes two portions, including a pump portion capable of use inside a living body and a drive portion for disposition outside the living body. The drive portion includes a pump drive system, including an assembly configured to cause the impeller to rotate in addition to an assembly configured to levitate the impeller. The present invention includes two separate versions of the pump drive system, including a first embodiment having a high temperature superconductor to levitate the impeller into a predetermined and substantially translationally fixed position spaced from said pump housing, and a rotating, motor driven magnet system to cause the impeller to rotate, and a second embodiment that incorporates a rotating superconductor, which will both levitate and rotate the impeller. Each embodiment of the pump drive system includes a cryostat vessel in which the superconductor is disposed for confining the superconductor in a liquid nitrogen environment to therefore maintain its temperature at 77 K in order to cause the superconductor to levitate magnets within the pump.
摘要翻译：本发明涉及一种血液泵送系统，其包括两部分，包括能够在生物体内使用的泵部分和用于在生物体外部配置的驱动部分。驱动部分包括泵驱动系统，该泵驱动系统包括构造成使得叶轮除了构造成悬浮叶轮的组件之外旋转的组件。本发明包括泵驱动系统的两个独立形式，包括具有高温超导体的第一实施例，其将叶轮悬浮到与所述泵壳体间隔开的预定和基本平移的固定位置，以及旋转的电动机驱动的磁体系统，叶轮旋转，以及包括旋转超导体的第二实施例，其将悬浮和旋转叶轮。泵驱动系统的每个实施例包括低温恒温器容器，其中设置超导体以将超导体限制在液氮环境中，从而将其温度保持在77K，以使超导体悬浮在泵内的磁体。

10. 发明申请

US20010016675A1 Stress reduction apparatus and method 有权
公开(公告)号：US20010016675A1
公开(公告)日：2001-08-23
申请号：US09843078
申请日：2001-04-27
申请人： Myocor, Inc.
发明人： Todd J. Mortier , Cyril J. Schweich JR. , Robert M. Vidlund
IPC分类号： A61M001/12
CPC分类号： A61F2/2481 , A61B17/00234 , A61B17/1227 , A61B2017/00243 , A61B2017/0404 , A61B2017/048 , A61B2017/0496 , A61F2/2487
摘要： The device and method for reducing heart wall stress. The device can be one which reduces wall stress throughout the cardiac cycle or only a portion of the cardiac cycle. The device can be configured to begin to engage, to reduce wall stress during diastolic filling, or begin to engage to reduce wall stress during systolic contraction. Furthermore, the device can be configured to include at least two elements, one of which engages full cycle and the other which engages only during a portion of the cardiac cycle.

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