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1. 发明授权

US09629781B2 Systems for capsule pressure-relief 有权
公开(公告)号：US09629781B2
公开(公告)日：2017-04-25
申请号：US14093568
申请日：2013-12-02
申请人： Patheon Pharmaceuticals Inc.
发明人： Lester David Fulper
IPC分类号： A61J3/07
CPC分类号： A61J3/074 , Y10S53/90
摘要： An system and method for coupling a capsule body and cap is provided. The system and method provide a first conduit configured to align a capsule body and a second conduit configured to align a capsule cap. The system and method provide for a pressure-relief cavity in at least one of the first conduit and the second conduit.

2. 发明授权

US07878366B2 Unit for filling containers with products, in particular, pharmaceutical products 有权
标题翻译：用于向容器填充产品，特别是药品的单元
公开(公告)号：US07878366B2
公开(公告)日：2011-02-01
申请号：US10515037
申请日：2003-05-20
申请人： Sergio Cicognani
发明人： Sergio Cicognani
IPC分类号： G07F11/00 , B65B5/10 , B65B5/00 , B65B61/20 , B65H29/68
CPC分类号： B65G47/848 , B65B5/08 , B65B5/103 , B65B35/14 , B65B35/18 , B65B37/04 , B65B37/14 , B65B57/14 , B65B57/20 , B65B65/08 , Y10S53/90
摘要： A unit (100) for filling containers (2) with products (1), in particular pharmaceutical products (1), includes a hopper (3,3a) containing a mass of products (1) in bulk, conveying means (5,6) aimed at feeding the products (1) leaving the hopper (3) along a predetermined path (P) up to a station (SR), where the containers (2) are filled with the products (1). The containers (2) are fed to the filling station (SR) by transporting means (4,C). A checking station (SC) for checking the products (1) is situated along the path (P) upstream of the filling station (SR). The conveying means (5,6) include first means (51,52,53) consisting of vibrating planes and second conveying means (6). The second conveying means (6) are situated at the checking station (SC) between the conveying vibrating planes means (51,52,53) and the filling station (SR). The second conveying means (6) are equipped with holding means (65) for holding single products (1) thus forming, on the second conveying means (6), a series of single products (1), spaced apart and moving forward to the filling station (SR) along a portion of the path (P).
摘要翻译：用于用产品（1），特别是药品（1）填充容器（2）的单元（100）包括容纳块体积的产品（1）的料斗（3,3a），输送装置（5,6 用于将产品（1）沿着预定路径（P）输送到站（SR）的产品（1），其中容器（2）填充有产品（1）。容器（2）通过输送装置（4，C）输送到加料站（SR）。用于检查产品（1）的检查站（SC）沿着加油站（SR）上游的路径（P）设置。输送装置（5,6）包括由振动平面和第二输送装置（6）组成的第一装置（51,52,53）。第二输送装置（6）位于输送振动平面装置（51,52,53）和加料站（SR）之间的检查站（SC）处。第二输送装置（6）配备有用于保持单个产品（1）的保持装置（65），从而在第二输送装置（6）上形成一系列单个产品（1），间隔开并向前移动到沿着路径（P）的一部分的加油站（SR）。

3. 发明申请

US20100018167A1 Method and Apparatus for Sealing Capsules 有权
标题翻译：密封胶囊的方法和装置
公开(公告)号：US20100018167A1
公开(公告)日：2010-01-28
申请号：US12376219
申请日：2007-07-19
申请人： Gabriel M. McCutcheon , Gunther Van Goolen , Stefaan Jaak Vanquickenborne
发明人： Gabriel M. McCutcheon , Gunther Van Goolen , Stefaan Jaak Vanquickenborne
IPC分类号： B65B51/10
CPC分类号： A61J3/072 , Y10S53/90
摘要： The present invention relates to a method and apparatus for sealing telescopically joined hardshell capsules. The method comprises i. placing the capsule (15) in a static sealing position (52) in a capsule carrier assembly (3); ii. in said sealing position (52), applying a sealing fluid uniformly to the gap of the capsule; iii. rotating the capsule (15) into a static suction position (53) angularly spaced from the sealing position (52); and iv. in said suction position (53), providing an area of low pressure around the capsule (15) so as to remove excess sealing liquid from the capsule.
摘要翻译：本发明涉及一种用于密封可伸缩连接的硬壳胶囊的方法和装置。该方法包括i。将胶囊（15）放置在胶囊承载组件（3）中的静态密封位置（52）中; ii。在所述密封位置（52）中，将密封流体均匀地施加到胶囊的间隙; iii。将所述胶囊（15）旋转到与所述密封位置（52）成角度地间隔开的静态抽吸位置（53）中。和iv。在所述抽吸位置（53）中，在胶囊（15）周围提供低压区域，以便从胶囊中除去多余的密封液体。

4. 发明授权

US07530213B2 Manual capsule loading machine 失效
标题翻译：手动胶囊装载机
公开(公告)号：US07530213B2
公开(公告)日：2009-05-12
申请号：US12002357
申请日：2007-12-17
申请人： Dene Barrett , Earle Wilkins
发明人： Dene Barrett , Earle Wilkins
IPC分类号： B65B35/56
CPC分类号： B65B35/56 , A61J3/075 , Y10S53/90
摘要： A capsule orienting and separation apparatus is provided which allows a multiplicity of gelatin capsule shells to be uniformly oriented in a separable condition and for the caps of those shells to be separated from the capsule bodies. The apparatus allows a multiplicity of capsule shells all to be concurrently oriented in an upright disposition by a manually operated mechanism. The capsule caps are all uniformly oriented atop the capsule bodies and are exposed for gripping by a capsule cap lift assembly. The capsule caps are concurrently lifted from the capsule bodies while the capsule bodies remain in position in a matrix of openings in a capsule receiving tray. The capsules can then be filled with capsule filler material and tamped down as appropriate. The capsule caps are then all concurrently replaced on the capsule bodies and the capsule caps and capsule bodies are then concurrently permanently sealed together. All of the steps of orientation, filling, and sealing are performed with a manually operable mechanism.
摘要翻译：提供了胶囊取向和分离装置，其允许多个明胶胶囊壳体在可分离状态下均匀地取向，并且这些壳体的盖帽与胶囊体分离。该装置允许多个胶囊壳全部通过手动操作的机构以直立的配置同时定向。胶囊盖均匀地定向在胶囊主体的顶部，并被胶囊盖提升组件暴露以夹持。胶囊盖同时从胶囊体提起，同时胶囊主体保持在胶囊容纳盘中的开口矩阵中的适当位置。然后可以将胶囊填充胶囊填充材料并适当地夯实。胶囊盖随后在胶囊体上同时被更换，胶囊盖和胶囊体然后同时被永久地密封在一起。取向，填充和密封的所有步骤都是用手动操作的机构进行的。

5. 发明申请

US20080256908A1 METHOD AND MACHINE FOR FILLING CAPSULES OR SIMILAR WITH AT LEAST ONE PRODUCT, IN PARTICULAR A PHARMACEUTICAL PRODUCT IN MICROTABLETS 失效
标题翻译：用于填充胶囊或类似于至少一种产品的方法和机器，特别是MICROTABLET中的药物产品
公开(公告)号：US20080256908A1
公开(公告)日：2008-10-23
申请号：US12104535
申请日：2008-04-17
申请人： Davide Frabetti
发明人： Davide Frabetti
IPC分类号： B65B1/32 , B65B1/08
CPC分类号： A61J3/074 , A61J2200/74 , B65B1/32 , G01G7/06 , G01G17/00 , Y10S53/90
摘要： A method and machine for filling capsules with at least one pharmaceutical product, whereby the bottom shell of each capsule is fed along a given path in time with a relative metering chamber for transferring a given quantity of product from a container into the bottom shell; a control device weighing the product in the metering chamber to cut off supply of the product into the metering chamber, when the weight of the product substantially equals a given reference value.
摘要翻译：一种用于用至少一种药物产品填充胶囊的方法和机器，由此每个胶囊的底壳在给定的路径上与相对计量室一起进给，用于将给定量的产品从容器转移到底壳中; 当产品的重量基本上等于给定的参考值时，控制装置称重计量室中的产品以切断产品进入计量室的供应。

6. 发明申请

US20080163590A1 Manual capsule loading machine and method 失效
公开(公告)号：US20080163590A1
公开(公告)日：2008-07-10
申请号：US12002357
申请日：2007-12-17
申请人： Dene Barrett , Earle Wilkins
发明人： Dene Barrett , Earle Wilkins
IPC分类号： B65B43/26 , B65B7/28
CPC分类号： B65B35/56 , A61J3/075 , Y10S53/90
摘要： A capsule orienting and separation apparatus is provided which allows a multiplicity of gelatin capsule shells to be uniformly oriented in a separable condition and for the caps of those shells to be separated from the capsule bodies. The apparatus allows a multiplicity of capsule shells all to be concurrently oriented in an upright disposition by a manually operated mechanism. The capsule caps are all uniformly oriented atop the capsule bodies and are exposed for gripping by a capsule cap lift assembly. The capsule caps are concurrently lifted from the capsule bodies while the capsule bodies remain in position in a matrix of openings in a capsule receiving tray. The capsules can then be filled with capsule filler material and tamped down as appropriate. The capsule caps are then all concurrently replaced on the capsule bodies and the capsule caps and capsule bodies are then concurrently permanently sealed together. All of the steps of orientation, filling, and sealing are performed with a manually operable mechanism.

7. 发明授权

US06782677B2 Tablet detecting system for molding tablet supplying apparatus 有权
标题翻译：用于成型片剂供应装置的片剂检测系统
公开(公告)号：US06782677B2
公开(公告)日：2004-08-31
申请号：US10407842
申请日：2003-04-04
申请人： Kyoung-Rae Cho , Kyung-Soo Park , Ju-Hwan Choi
发明人： Kyoung-Rae Cho , Kyung-Soo Park , Ju-Hwan Choi
IPC分类号： B65B130
CPC分类号： B29C45/768 , B29C45/02 , B29C45/462 , B29C2945/761 , B29C2945/76167 , B29C2945/76331 , B29C2945/76832 , Y10S53/90
摘要： A tablet detecting system ascertains whether a tablet exists in a receiving hole of a loader unit used for a molding tablet supplying apparatus or, if exists, whether the tablet has a standard size, by using a mechanical contact manner. The tablet detecting system has a push rod, a contact head, an insulation plate, a conductive assembly and a control unit. The push rod is inserted into the receiving hole and moves upward just as high as the tablet. The contact head is formed on a top of the push rod and the insulation plate is located over the contact head. The conductive assembly is formed in the insulation plate and the control unit is electrically connected to the conductive assembly. When the tablet in the receiving hole has a standard size, the contact head mechanically touches the conductive assembly and gives electrical connection to the conductive assembly, and the control unit senses the electrical connection. The conductive assembly may be a pair of conductive pads formed separately on a bottom surface of the insulation plate, or a pair of plungers inserted into a pair of cylindrical bodies each formed in the insulation plate and spaced apart from each other.
摘要翻译：片剂检测系统确定片剂是否存在于用于成型片剂供应装置的装载器单元的接收孔中，或者如果存在，则通过机械接触方式确定片剂是否具有标准尺寸。片剂检测系统具有推杆，接触头，绝缘板，导电组件和控制单元。将推杆插入接收孔并向上移动，与片剂一样高。接触头形成在推杆的顶部上，绝缘板位于接触头的上方。导电组件形成在绝缘板中，并且控制单元电连接到导电组件。当接收孔中的片剂具有标准尺寸时，接触头机械地接触导电组件并且与导电组件电连接，并且控制单元感测电连接。导电组件可以是分别形成在绝缘板的底表面上的一对导电焊盘，或者插入一对圆柱体中的一对柱塞，每个柱体形成在绝缘板中并彼此间隔开。

8. 发明申请

US20020108356A1 Positive count rotary slat packaging apparatus and related methods 失效
公开(公告)号：US20020108356A1
公开(公告)日：2002-08-15
申请号：US10119500
申请日：2002-04-10
申请人： Aylward Enterprises, Inc.
发明人： John T. Aylward
IPC分类号： B65B005/00
CPC分类号： B65B5/103 , B65B35/08 , B65B57/14 , B65B57/20 , Y10S53/90
摘要： An automated positive count rotary slat packaging apparatus and related methods include independently rotatable rotary slats. In one embodiment, the apparatus also includes a positive count mechanism disposed in the pill delivery path adjacent the containers and a controller which is capable of generating an alarm or determining when a bottle is filled incorrectly. Accordingly, underfilled containers can be independently filled by further rotating only the respective rotary slat. A drive device for each rotary slat is also provided having frustoconical drive wheels connected to the ends of counterrotating drive shafts. The drive wheels, which are driven by a motor, engage corresponding frustoconical drive surfaces of the rotary slats to thereby rotate the slats.

9. 发明授权

US06363687B1 Secured cell, rapid fill automated tablet order filling system 失效
标题翻译：安全细胞，快速填充自动化药片灌装系统
公开(公告)号：US06363687B1
公开(公告)日：2002-04-02
申请号：US09519196
申请日：2000-03-06
申请人： Robert A. Luciano , Lawrence W. Luciano , Richard L. Smith
发明人： Robert A. Luciano , Lawrence W. Luciano , Richard L. Smith
IPC分类号： B65B5700
CPC分类号： B65B5/103 , B65B37/08 , B65B57/14 , B65B57/20 , Y10S53/90
摘要： The present invention tablet filler device system includes a plurality of individually secured cells with a tablet hopper and drum functionally adapted to regulate and orient gravity outflow of tablets, a gravity feed chute connected to and downstream from the hopper to singularly align and feed tablets, and a rotatable starwheel having slots to receive tablets from the feed chute to move tablets to a container filling substation. There is also a tablet inspection mechanism located on the feed chute to discern quality characteristics of tablets moving down the feed chute in accordance with a predetermined standard, and a tablet ejector to eject unacceptable tablets. A stepper drive motor with a counter capability for driving the starwheel in a step fashion for controlled release of tablets is included, and an optional counting verification sensor. The cells are interconnected for computer controlled automatic order filling for a variety of tablet types and container sizes.
摘要翻译：本发明的片剂填充装置系统包括多个单独固定的细胞，其具有功能上适于调节和定向片剂的重力流出的片剂料斗和鼓，连接到料斗上游和下游的重力进料槽，以单独对准和进料片剂，以及具有槽的可旋转星形轮具有从进料槽接收片剂以将片剂移动到容器填充变电站。还有一个位于进料槽上的片剂检查机构，以便根据预定的标准来辨别片剂向下移动进料槽的质量特征，以及一个药片喷射器来排出不可接受的片剂。包括具有针对片剂控制释放的步进驱动星形轮的计数器能力的步进驱动马达和可选的计数验证传感器。电池相互连接，用于计算机控制的自动订单填充，适用于各种平板电脑类型和容器尺寸。

10. 发明授权

US06260332B1 Apparatus for and method of manufacturing soft capsules 有权
标题翻译：软胶囊的制造方法及其制造方法
公开(公告)号：US06260332B1
公开(公告)日：2001-07-17
申请号：US09246236
申请日：1999-02-08
申请人： Tetsuo Takayanagi
发明人： Tetsuo Takayanagi
IPC分类号： B65B4700
CPC分类号： B65B9/023 , A61J3/07 , Y10S53/90
摘要： An apparatus for and a method of manufacturing soft capsules wherein a filling material such as liquid medicine is encapsulated by two pieces of gelatin sheet are provided. The soft capsule manufacturing apparatus comprises a pair of die rolls that are close to and confront each other, each die role having capsule pockets in a plurality of rows, and a nozzle segment having an inverse mountain-like projection for supplying a filling material, wherein the inverse mountain-like projection has curved faces that are positioned in confronting relation with each other at right and left sides about the lower end central portion thereof, have nozzle holes, wherein the inverse mountain-like projection confronts a curved recess that is surrounded by curved peripheral surfaces of the die rolls at the upper sides thereof, and wherein two gelatin sheets are supplied between the die rolls from the upper portion thereof to receive the filling material therein corresponding to the capsule pockets of each die roll to manufacture soft capsules, and wherein the nozzle holes are arranged on the curved faces in a plurality of rows corresponding to the capsule pockets provided on the die rolls in a plurality of rows. With this arrangement, when the pump is actuated one time, the filling material is supplied at a time from the nozzle holes arranged in a plurality of rows to the capsule pockets arranged in a plurality of rows, leading to remarkable increase of the production of the capsule pockets.
摘要翻译：提供了一种软胶囊的制造装置及其制造方法，其中填充材料如液体药物被两片明胶片包封。软胶囊制造装置包括彼此靠近并相对的一对模具辊，每个模具角色具有多排的胶囊袋和具有用于供应填充材料的反向山形突起的喷嘴段，其中反山形突起具有围绕其下端中心部分在左右侧相对定位的弯曲面，具有喷嘴孔，其中，反向山状突起面对由模具的上表面弯曲的周边表面，并且其中两个明胶片从其上部供应在模具辊之间，以在其中接收与每个模具辊的胶囊袋相对应的填充材料，以制造软胶囊，并且其特征在于，所述喷嘴孔配置在与设置的胶囊口袋对应的多列中的弯曲面上在模具上以多行排列。通过这种布置，当泵一次启动时，填充材料一次从布置成多排的喷嘴孔被提供到排列成多行的胶囊袋中，导致显着增加胶囊口袋。

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