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1. 发明申请

US20180306701A1 OPTICAL TEST PLATFORM 审中-公开
公开(公告)号：US20180306701A1
公开(公告)日：2018-10-25
申请号：US15958771
申请日：2018-04-20
申请人： bioMerieux, Inc.
发明人： Jack R. HOFFMANN, JR. , Gregory R. MAES , Jeffrey Edward PRICE , Jared Ian BULLOCK , Samuel B. CRANDALL , Jacky S. YAM , Christopher George KOCHER , Walter J. CLYNES
IPC分类号： G01N21/03 , G01N33/487 , G01N1/10 , G01N21/47
CPC分类号： B01L3/50853 , B01L2200/14 , B01L2300/0654 , B01L2300/0803 , B01L2300/12 , G01N1/10 , G01N15/06 , G01N21/01 , G01N21/274 , G01N21/4738 , G01N21/474 , G01N21/4785 , G01N21/51 , G01N21/5907 , G01N21/8806 , G01N21/93 , G01N33/487 , G01N2015/0693 , G01N2021/0168 , G01N2021/4769 , G01N2021/598 , G01N2201/126 , G01N2201/12707
摘要： Provided herein are an optical test platform and corresponding method of manufacturing the same. The test platform may include a shell defining a cavity for receiving a sample tube, a first aperture, and a second aperture. The first aperture and the second aperture of the shell may each be configured to optically couple the cavity with an exterior of the shell. The test platform may further include a first window and a second window embedded in the shell. The first window may seal a first aperture and the second window may seal a second aperture. The first window and second window may each permit the optical coupling of the cavity with the exterior of the shell. The first window and the second window may be optically coupled via the cavity, and the shell may prohibit optical coupling between the first window and the second window through the shell.

2. 发明授权

US09389408B2 3D microscope and methods of measuring patterned substrates 有权
标题翻译： 3D显微镜和测量图案基板的方法
公开(公告)号：US09389408B2
公开(公告)日：2016-07-12
申请号：US13172686
申请日：2011-06-29
申请人： Zhen Hou , James Jianguo Xu , Ken Kinsun Lee , James Nelson Stainton , Hung Phi Nguyen , Rusmin Kudinar , Ronny Soetarman
发明人： Zhen Hou , James Jianguo Xu , Ken Kinsun Lee , James Nelson Stainton , Hung Phi Nguyen , Rusmin Kudinar , Ronny Soetarman
IPC分类号： H04N13/02 , G02B21/36 , G01N21/956
CPC分类号： G02B21/006 , G01N21/9501 , G01N21/956 , G01N2021/0168 , G02B21/0016 , G02B21/0028 , G02B21/0032 , G02B21/367 , G06T7/60 , G06T2207/10056 , G06T2207/10152 , G06T2207/20068 , G06T2207/30148
摘要： A three-dimensional (3D) microscope for patterned substrate measurement can include an objective lens, a reflected illuminator, a transmitted illuminator, a focusing adjustment device, an optical sensor, and a processor. The focusing adjustment device can automatically adjust the objective lens focus at a plurality of Z steps. The optical sensor can be capable of acquiring images at each of these Z steps. The processor can control the reflected illuminator, the transmitted illuminator, the focusing adjustment device, and the optical sensor. The processor can be configured to capture first and second images at multiple Z steps, the first image with the pattern using the reflected illuminator and the second image without the pattern using one of the reflected illuminator and the transmitted illuminator.
摘要翻译：用于图案化衬底测量的三维（3D）显微镜可以包括物镜，反射照明器，透射照明器，聚焦调节装置，光学传感器和处理器。聚焦调节装置可以在多个Z步骤自动调节物镜焦点。光学传感器能够在这些Z步骤的每个步骤中获取图像。处理器可以控制反射照明器，透射照明器，聚焦调节装置和光学传感器。处理器可以被配置成以多个Z步骤捕获第一和第二图像，第一图像使用反射照明器的图案，而不使用反射照明器和透射照明器之一的图案的第二图像。

3. 发明授权

US5668887A Coating density analyzer and method using non-synchronous TDI camera 失效
标题翻译：涂层密度分析仪和使用非同步TDI相机的方法
公开(公告)号：US5668887A
公开(公告)日：1997-09-16
申请号：US425640
申请日：1995-04-20
申请人： H. Galen Parker , Richard Dean Young
发明人： H. Galen Parker , Richard Dean Young
IPC分类号： G01N21/01 , G01N21/89 , G01N21/892 , G01N21/93 , G01N21/95 , H04N1/00 , H04N5/372 , H04N7/18 , G01N21/00
CPC分类号： H04N5/37206 , G01N21/8422 , G01N21/89 , G01N21/8903 , H04N3/1525 , G01N2021/0168 , G01N2021/8427 , G01N2021/8838 , G01N2021/8887 , G01N2021/936 , G01N2201/102
摘要： An image processor based system and method for recognizing predefined-types of coating density imperfections in a web, specifically continuous type or streak imperfections. Continuous type imperfections are recognized in a continuous web moved at a certain rate through an imaging region illuminated by a stripe of substantially constant illumination. A time-delay integrating CCD camera is focused on the illuminated imaging region. The TDI CCD camera comprises an array of N rows of M light sensitive CCD elements each imaged on a fixed discrete pixel-related image area of the illuminated imaging region. The charge levels accumulated in the CCD elements of each row are shifted to the succeeding row or CCD elements and summed with the charge levels therein at a line shift clock frequency that ensures that an asynchronous relationship exists with respect to the incremental movement of the web. During the clock cycle of the N rows, the corresponding pixel areas of the illuminated web shift asynchronously or creep through the discrete pixel-related image areas. The accumulated pixel charge values derived from the pixel-related image areas of the illuminated region of said moving web emphasize imaging of longitudinal streak imperfections in the web due to the asynchronous movement the web.
摘要翻译：一种基于图像处理器的系统和方法，用于识别网中预定类型的涂层密度缺陷，特别是连续类型或条纹缺陷。通过由基本上恒定的照明条纹照射的成像区域以一定的速率移动的连续幅材中识别出连续型缺陷。集成CCD相机的延时集中在照明成像区域。 TDI CCD摄像机包括N行M个光敏CCD元件的阵列，每个成像在照明成像区域的固定离散像素相关图像区域上。累积在每行的CCD元件中的电荷电平被移动到后面的行或CCD元件，并且以线移位时钟频率与其中的电荷电平相加，以确保相对于幅的增量移动存在异步关系。在N行的时钟周期期间，被照射的web的相应的像素区域异步地移动或者通过离散的像素相关的图像区域来移动。从所述移动幅材的被照射区域的像素相关图像区域导出的累积的像素电荷值强调了由于网状物的异步移动而在幅材中的纵向条纹缺陷的成像。

4. 发明授权

US11779931B2 Optical density instrument and systems and methods using the same 有权
公开(公告)号：US11779931B2
公开(公告)日：2023-10-10
申请号：US17470717
申请日：2021-09-09
申请人： bioMerieux, Inc.
发明人： Perry D. Stamm , Joel Patrick Harrison , Gregory R Maes , Jeffrey Edward Price , Jack R. Hoffmann, Jr. , John Kenneth Korte , Daniel Joseph Pingel , Walter J. Clynes , Sean Gregory Furman , Leonard H. Schleicher , Christopher George Kocher , Brian David Peterson , Jacky S. Yam
IPC分类号： B01L3/00 , G01N21/01 , G01N21/59 , G01N21/47 , G01N1/10 , G01N21/27 , G01N33/487 , G01N21/03 , G01N15/06 , G01N21/51 , G01N21/88 , G01N21/93
CPC分类号： B01L3/50853 , G01N1/10 , G01N15/06 , G01N21/01 , G01N21/0303 , G01N21/274 , G01N21/4738 , G01N21/4785 , G01N21/51 , G01N21/5907 , G01N21/8806 , G01N21/93 , G01N33/487 , G01N33/48735 , B01L2200/14 , B01L2300/0654 , B01L2300/0803 , B01L2300/12 , G01N21/474 , G01N2015/0693 , G01N2021/0168 , G01N2021/0389 , G01N2021/4769 , G01N2021/598 , G01N2201/126 , G01N2201/12707
摘要： Instruments, systems, and methods for measuring optical density of microbiological samples are provided. In particular, optical density instruments providing improved safety, efficiency, comfort, and convenience are provided. Such optical density instruments include a handheld portion and a base station. The optical density instruments may be used in systems and methods for measuring optical density of biological samples.

5. 发明申请

US20160252714A1 3D Microscope And Methods Of Measuring Patterned Substrates 审中-公开
公开(公告)号：US20160252714A1
公开(公告)日：2016-09-01
申请号：US15150411
申请日：2016-05-09
申请人： Zeta Instruments, Inc.
发明人： Zhen Hou , James Jianguo Xu , Ken Kinsun Lee , James Nelson Stainton , Hung Phi Nguyen , Rusmin Kudinar , Ronny Soetarman
IPC分类号： G02B21/00 , G06T7/00
CPC分类号： G02B21/006 , G01N21/9501 , G01N21/956 , G01N2021/0168 , G02B21/0016 , G02B21/0028 , G02B21/0032 , G02B21/367 , G06T7/60 , G06T2207/10056 , G06T2207/10152 , G06T2207/20068 , G06T2207/30148
摘要： A three-dimensional (3D) microscope for patterned substrate measurement can include an objective lens, a reflected illuminator, a transmitted illuminator, a focusing adjustment device, an optical sensor, and a processor. The focusing adjustment device can automatically adjust the objective lens focus at a plurality of Z steps. The optical sensor can be capable of acquiring images at each of these Z steps. The processor can control the reflected illuminator, the transmitted illuminator, the focusing adjustment device, and the optical sensor. The processor can be configured to capture first and second images at multiple Z steps, the first image with the pattern using the reflected illuminator and the second image without the pattern using one of the reflected illuminator and the transmitted illuminator.

6. 发明申请

US20100082011A1 FLUID DETECTION IN AN ENTERAL FEEDING SET 有权
标题翻译：输液装置中的流体检测
公开(公告)号：US20100082011A1
公开(公告)日：2010-04-01
申请号：US12240654
申请日：2008-09-29
申请人： Thomas G. Lewis , William J. Byrd , Joseph A. Hudson
发明人： Thomas G. Lewis , William J. Byrd , Joseph A. Hudson
IPC分类号： A61M5/168 , A61M5/142
CPC分类号： A61J15/0026 , A61J15/0076 , A61J15/0088 , A61J2200/76 , A61M5/14232 , A61M5/16886 , A61M2005/1402 , A61M2205/331 , A61M2205/3313 , A61M2205/3334 , G01N21/3577 , G01N21/59 , G01N2021/0168
摘要： Detection of fluid conditions in an administration set. A light source is positioned to transmit an infrared light through administration set tubing and any fluid therein. A light sensor senses the infrared light transmitted through the tubing and generates an output signal. A frequency of the output signal is a function of an intensity of the light transmitted through the tubing. A processor receives and determines the frequency of the output signal, and compares the determined frequency to threshold frequency values to determine whether fluid is in the tubing. The processor also monitors the generated output signal to determine if the frequency of the output signal changes over time, and determines whether fluid is flowing in the tubing as a function of the determined change in frequency.
摘要翻译：检测给药组中的液体状况。光源被定位成通过管线管和其中的任何流体传输红外光。光传感器感测通过管道传输的红外光，并产生输出信号。输出信号的频率是通过管道传输的光的强度的函数。处理器接收并确定输出信号的频率，并将确定的频率与阈值频率值进行比较，以确定流体是否在管道中。处理器还监视所产生的输出信号以确定输出信号的频率是否随时间而变化，并且根据确定的频率变化来确定流体是否在管道中流动。

7. 发明授权

US4902896A Infrared fluid analyzer 失效
标题翻译：红外流体分析仪
公开(公告)号：US4902896A
公开(公告)日：1990-02-20
申请号：US47650
申请日：1987-05-08
申请人： Glenn H. Fertig, Sr. , Adrian C. Billetdeaux
发明人： Glenn H. Fertig, Sr. , Adrian C. Billetdeaux
IPC分类号： A61M16/10 , G01N21/01 , G01N21/35
CPC分类号： G01N21/3504 , A61M16/104 , G01N2021/0168 , G01N2201/1211 , G01N2201/128
摘要： An infrared fluid analyzer for the detection of end tidal CO.sub.2. The analyzer is comprised of an IR source that irradiates a chamber filled with gas. CO.sub.2 present in the chamber absorbs the IR radiation at a certain wavelength. An IR detector determines the amount of IR radiation passing through the chamber unabsorbed and produces a signal corresponding to the CO.sub.2 in the chamber. At predetermined intervals a zero gas is reintroduced into the chamber for the system to be recalibrated. A span gas is only needed initially for calibration purposes.
摘要翻译：用于检测尾气CO2的红外流体分析仪。分析仪由辐射充满气体的室的IR源组成。存在于腔室中的CO 2以一定波长吸收IR辐射。 IR检测器确定通过腔室的IR辐射量未被吸收并产生对应于腔室中的CO 2的信号。以预定间隔，将零气体重新引入室中，以使系统被重新校准。最初仅需要量程气体用于校准目的。

8. 发明授权

US11673141B2 Method, apparatus, and computer program product for controlling components of a detection device 有权
公开(公告)号：US11673141B2
公开(公告)日：2023-06-13
申请号：US17474544
申请日：2021-09-14
申请人： bioMerieux, Inc.
发明人： Joel Patrick Harrison , John Kenneth Korte , Jeffrey Edward Price
IPC分类号： G01N21/01 , G01N15/06 , G01N21/51 , G01N21/88 , G01N21/93 , B01L3/00 , G01N21/59 , G01N21/47 , G01N1/10 , G01N21/27 , G01N33/487 , G01N21/03
CPC分类号： B01L3/50853 , G01N1/10 , G01N15/06 , G01N21/01 , G01N21/0303 , G01N21/274 , G01N21/4738 , G01N21/4785 , G01N21/51 , G01N21/5907 , G01N21/8806 , G01N21/93 , G01N33/487 , G01N33/48735 , B01L2200/14 , B01L2300/0654 , B01L2300/0803 , B01L2300/12 , G01N21/474 , G01N2015/0693 , G01N2021/0168 , G01N2021/0389 , G01N2021/4769 , G01N2021/598 , G01N2201/126 , G01N2201/12707
摘要： A method, computer program product, and apparatus are provided for controlling components of a detection device. The device may detect turbidity of liquid with sensors such as a density sensor and/or nephelometric sensor. A light modulation pattern may reduce or eliminate interference in sensor readings. Readings may be performed during off cycles of an illumination light to reduce interference but to provide improved visibility of a tube. Dark and light sensor readings may be performed with an emitter respectively off or on to account for ambient light in subsequent readings. Readings from the density sensor and/or nephelometric sensor may be used to calculate McFarland values. The device may be zeroed based on an emitter level that results in a sensor reading satisfying a predetermined criterion.

9. 发明申请

US20180304255A1 TIP RESISTANT OPTICAL TESTING INSTRUMENT 审中-公开
公开(公告)号：US20180304255A1
公开(公告)日：2018-10-25
申请号：US15958777
申请日：2018-04-20
申请人： bioMerieux, Inc.
发明人： Jack R. Hoffmann, JR. , Gregory R. Maes
IPC分类号： B01L3/00 , G01N21/01 , G01N21/59
CPC分类号： B01L3/50853 , B01L2200/14 , B01L2300/0654 , B01L2300/0803 , B01L2300/12 , G01N1/10 , G01N15/06 , G01N21/01 , G01N21/274 , G01N21/4738 , G01N21/474 , G01N21/4785 , G01N21/51 , G01N21/5907 , G01N21/8806 , G01N21/93 , G01N33/487 , G01N2015/0693 , G01N2021/0168 , G01N2021/4769 , G01N2021/598 , G01N2201/126 , G01N2201/12707
摘要： Apparatuses and associated methods of manufacturing are described that provide a tip resistant optical testing instrument configured to rest on a surface. The optical testing instrument includes a shell defining a cavity for receiving a sample tube. The shell includes a bottom shell surface, wherein the bottom shell surface defines at least one support element, wherein the at least one support element is configured to engage the surface to support the optical testing instrument in a testing position, and a translational surface configured to engage the surface to support the optical testing instrument in an angled position. In an instance in which the optical testing instrument tilts from the testing position to the angled position, the translational surface is configured to engage the surface contacting the translational surface to prevent the optical testing instrument from tipping further and allow the optical testing instrument to return to the testing position.

10. 发明申请

US20140296775A1 FLUID DETECTION IN AN ENTERAL FEEDING SET 有权
标题翻译：输液装置中的流体检测
公开(公告)号：US20140296775A1
公开(公告)日：2014-10-02
申请号：US14303919
申请日：2014-06-13
申请人： Covidien LP
发明人： Thomas G. Lewis , William J. Byrd , Joseph A. Hudson
IPC分类号： A61J15/00 , A61M5/168 , G01N21/35 , A61M5/142
CPC分类号： A61J15/0026 , A61J15/0076 , A61J15/0088 , A61J2200/76 , A61M5/14232 , A61M5/16886 , A61M2005/1402 , A61M2205/331 , A61M2205/3313 , A61M2205/3334 , G01N21/3577 , G01N21/59 , G01N2021/0168
摘要： Detection of fluid conditions in an administration set. A light source is positioned to transmit an infrared light through administration set tubing and any fluid therein. A light sensor senses the infrared light transmitted through the tubing and generates an output signal. A frequency of the output signal is a function of an intensity of the light transmitted through the tubing. A processor receives and determines the frequency of the output signal, and compares the determined frequency to threshold frequency values to determine whether fluid is in the tubing. The processor also monitors the generated output signal to determine if the frequency of the output signal changes over time, and determines whether fluid is flowing in the tubing as a function of the determined change in frequency.
摘要翻译：检测给药组中的液体状况。光源被定位成通过管线管和其中的任何流体传输红外光。光传感器感测通过管道传输的红外光，并产生输出信号。输出信号的频率是通过管道传输的光的强度的函数。处理器接收并确定输出信号的频率，并将确定的频率与阈值频率值进行比较，以确定流体是否在管道中。处理器还监视所产生的输出信号以确定输出信号的频率是否随时间而变化，并且根据确定的频率变化来确定流体是否在管道中流动。

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