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1. 发明公开

US20230272862A1 MULTIPLE-TUBE PINCH VALVE ASSEMBLY 审中-公开
公开(公告)号：US20230272862A1
公开(公告)日：2023-08-31
申请号：US18113173
申请日：2023-02-23
申请人： Terumo BCT, Inc.
发明人： Andrew GLOOR , Brian William WARD , Alexander BROWN , Briden Ray STANTON , Brett BAEVERSTAD , Chuankun WANG , Stuart MCKNIGHT , Daniel CLEMENT
IPC分类号： F16K7/04 , F16K31/04 , F16K27/02
CPC分类号： F16K7/045 , F16K31/047 , F16K27/0236 , F16K31/52491
摘要： A multi-tubing pinch valve assembly including a receiving space defined between a pinch protrusion and tubing contact body. The multi-tubing pinch valve assembly is moveable between a retracted state and an extended state. In the extended state, multiple tubes disposed in the receiving space are pinched, restricting flow therethrough. In the retracted state, multiple tubes are capable of being loaded into and/or out of the receiving space.

2. 发明申请

US20170275587A1 MULTI-ORGAN MEDIA COMPOSITIONS AND METHODS OF THEIR USE 审中-公开
公开(公告)号：US20170275587A1
公开(公告)日：2017-09-28
申请号：US15513948
申请日：2015-09-24
申请人： Los Alamos National Security, LLC
发明人： Rashi Iyer , Jennifer F. Harris , Jen-Huang Huang , Pulak Nath , Andrzej Przekwas
IPC分类号： C12N5/07 , B01L3/00
CPC分类号： G01N33/5064 , B01L3/5027 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L2200/027 , B01L2300/0627 , B01L2300/0681 , B01L2300/0832 , B01L2300/0887 , B01L2300/123 , B01L2400/0481 , B01L2400/0633 , C12N5/06 , C12N5/067 , F16K7/045 , G01N33/5008 , G01N33/5014 , G01N33/5082
摘要： Disclosed herein are media for culture of cells, tissues, and/or organs. The media formulations disclosed herein can be used to support growth, viability, and/or function of one or more than one cell type, tissue, or organ. In some embodiments, one or more cell types, tissues, organ devices, and/or organs are contacted with a disclosed culture medium under conditions sufficient to support growth, viability, and/or function of the cell types, tissues, and/or organs. The disclosed media can be used in methods of culturing multiple cell types, and in some examples, is used in a platform device including one or more organ devices, for example, by circulating the medium through the one or more organ devices in the platform.

3. 发明授权

US09763364B1 Heat transfer liquid flow method and apparatus 有权
公开(公告)号：US09763364B1
公开(公告)日：2017-09-12
申请号：US15197535
申请日：2016-06-29
申请人： Intel Corporation
发明人： Christian Amoah-Kusi
IPC分类号： H01F7/00 , H01F1/00 , H05K7/20 , F28F13/08
CPC分类号： H05K7/20772 , F16K7/045 , F16K31/0651 , F16K31/0672 , F28F13/08 , F28F27/02 , F28F2255/02 , H05K7/20254 , H05K7/20272 , H05K7/20281
摘要： Apparatus and method to facilitate heat transfer fluid flow are disclosed herein. A flexible tube having first and second ends facilitates a heat transfer fluid to flow from the first end to the second end. Ferromagnetic material encircles at least an outside portion of a length of the flexible tube, and a plurality of coil windings encircles the ferromagnetic material. The flexible tube is to be compressed to reduce an amount of flow of the heat transfer fluid from the first end to the second end by expansion of the ferromagnetic material around the flexible tube, in response to an application of a current to the plurality of coil windings.

4. 发明申请

US20170108126A1 APPARATUS AND METHODS FOR FLUID PROCESSING AND FLOW CONTROL 审中-公开
公开(公告)号：US20170108126A1
公开(公告)日：2017-04-20
申请号：US15383108
申请日：2016-12-19
申请人： BIOTECHFLOW LTD.
发明人： Martin John Hofmann
IPC分类号： F16K7/04 , B01L3/00 , F16L11/10
CPC分类号： F16K7/04 , B01J19/0093 , B01J2219/00783 , B01J2219/00792 , B01J2219/00817 , B01J2219/00896 , B01L3/502 , B01L3/502738 , B01L2200/12 , B01L2300/0681 , B01L2300/0832 , B01L2300/0864 , B01L2300/0867 , B01L2300/123 , B01L2300/14 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , F16K7/045 , F16K7/07 , F16L11/10 , Y10T137/0318 , Y10T137/877
摘要： Fluid processing apparatus has a prefabricated branched network of flexible tubing, for conducting process fluid between process elements of the apparatus, and control valves. A tubing support has opposable front and rear plates which define a pattern of support channels between them in which the flexible tubing network lies, so that the support channels limit or prevent expansion of the flexible tubes. Standard non-reinforced tubing can then be used for high-pressure work. The support body plates can be separated to open the channels for insertion or removal of the flexible tubing. The front plate may be transparent. The control valves operate by simply pressing on the tubing in the support channels to block flow, without invasion of the flow path. The tubing sets can be easily replaced, cleaned or sterilized. The invention is useful in a range of controlled-flow processes e.g. chromatography and filtration.

5. 发明授权

US09546747B2 Apparatus and methods for fluid processing and flow control 有权
标题翻译：用于流体处理和流量控制的装置和方法
公开(公告)号：US09546747B2
公开(公告)日：2017-01-17
申请号：US14112261
申请日：2012-04-18
申请人： Martin John Hofmann
发明人： Martin John Hofmann
IPC分类号： F16K7/04 , F16L11/10 , B01J19/00 , B01L3/00 , F16K7/07
CPC分类号： F16K7/04 , B01J19/0093 , B01J2219/00783 , B01J2219/00792 , B01J2219/00817 , B01J2219/00896 , B01L3/502 , B01L3/502738 , B01L2200/12 , B01L2300/0681 , B01L2300/0832 , B01L2300/0864 , B01L2300/0867 , B01L2300/123 , B01L2300/14 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , F16K7/045 , F16K7/07 , F16L11/10 , Y10T137/0318 , Y10T137/877
摘要： Fluid processing apparatus has a prefabricated branched network of flexible tubing, for conducting process fluid between process elements of the apparatus, and control valves. A tubing support has opposable front and rear plates which define a pattern of support channels between them in which the flexible tubing network lies, so that the support channels limit or prevent expansion of the flexible tubes. Standard non-reinforced tubing can then be used for high-pressure work. The support body plates can be separated to open the channels for insertion or removal of the flexible tubing. The front plate may be transparent. The control valves operate by simply pressing on the tubing in the support channels to block flow, without invasion of the flow path. The tubing sets can be easily replaced, cleaned or sterilized. The invention is useful in a range of controlled-flow processes e.g. chromatography and filtration.
摘要翻译：流体处理设备具有预制的柔性管的分支网络，用于在设备的过程元件和控制阀之间传导过程流体。管道支撑件具有可相对的前板和后板，其限定了柔性管网位于其间的支撑通道的图案，使得支撑通道限制或防止柔性管的膨胀。然后可以使用标准的非增强管道进行高压工作。支撑体板可以分开以打开用于插入或移除柔性管的通道。前板可能是透明的。控制阀通过简单地按压支撑通道中的管道来阻止流动，而不会侵入流动路径。管套可以方便地更换，清洁或消毒。本发明可用于一系列受控流程，例如，色谱和过滤。

6. 发明授权

US09435459B2 Solenoid pinch valve apparatus and method for medical fluid applications having reduced noise production 有权
标题翻译：用于医疗液体应用的电磁夹管阀装置和方法具有降低的噪音产生
公开(公告)号：US09435459B2
公开(公告)日：2016-09-06
申请号：US12479373
申请日：2009-06-05
申请人： John Bedingfield
发明人： John Bedingfield
IPC分类号： F16K7/04 , F16K31/06 , F16K31/04
CPC分类号： A61M39/28 , A61M1/28 , F16K7/045 , F16K31/046 , F16K31/0672 , F16K31/0675
摘要： A low noise solenoid valve system includes a solenoid valve; and a controller configured to perform a power actuation sequence in which power to the solenoid valve undergoes a plurality of cycles that switch from an actuation level power to a hold level power, wherein the actuation level power is increased at each subsequent cycle, and wherein the actuation power level of one of the plurality of cycles is sufficient to fully actuate the solenoid valve.
摘要翻译：低噪音电磁阀系统包括电磁阀; 以及控制器，被配置为执行动力驱动顺序，其中所述电磁阀的动力经历从致动水平功率切换到保持水平功率的多个循环，其中所述致动水平功率在每个后续循环中增加，并且其中多个循环中的一个循环的致动功率水平足以完全致动电磁阀。

7. 发明申请

US20140013938A1 SHAFT SEALING DEVICE AND VALVE STRUCTURE USING THE SAME 审中-公开
标题翻译：密封装置和阀结构使用相同
公开(公告)号：US20140013938A1
公开(公告)日：2014-01-16
申请号：US14036408
申请日：2013-09-25
申请人： Kitz Corporation
发明人： Kazuhiro AOKI , Tomoya YAMASAKI , Chikashi GOMI
IPC分类号： F15B21/00
CPC分类号： F15B21/00 , F16J15/164 , F16J15/3208 , F16J15/3296 , F16J15/56 , F16K7/045 , F16K31/02 , F16K31/025 , G05D7/0635 , G05D7/0641 , H01L41/193 , Y10T137/2202 , Y10T137/2213 , Y10T137/87169 , Y10T137/87217
摘要： A shaft sealing device switches a sealing state and an unsealing state of a fluid, with high sealing performance maintained, because no abrasion accompanies movement of a sealing material or a sealing member, enabling feeding a fluid at a predetermined flow rate, and adjusts the expanding rate of the sealing material with the quantity of an external electric signal and accordingly adjusts the contact face pressure to enable controlling the amount of leakage of the fluid highly precisely, so that it can be used for all applications. The shaft sealing device includes a shaft sealing body formed of a macromolecular material and made expansible or contractible, or deformable, through external electrostimuli applied to a shaft sealing portion disposed in a device body, and flow passages disposed in the shaft sealing portion for feeding the fluid leaked due to the expansion or contraction, or the deformation, of the shaft sealing body.
摘要翻译：轴密封装置切换流体的密封状态和开封状态，保持高的密封性能，因为没有磨损伴随着密封材料或密封构件的移动，能够以预定流量供给流体，并且调节膨胀密封材料与外部电信号量的比率，并且因此调节接触面压力，以便能够高精度地控制流体的泄漏量，从而可以用于所有应用。轴封装置包括：由大分子材料形成的轴封体，通过施加到设置在装置主体中的轴密封部分的外部静电，可膨胀或收缩或变形，以及设置在轴封部分中的流动通道，流体由于轴封体的膨胀或收缩或变形而泄漏。

8. 发明申请

US20130118619A1 VALVE DEVICE FOR CONTROLLING A FLOW OF A FLUID THROUGH A FLUID CHANNEL, ARRANGEMENT AND MULTI-WAY VALVE DEVICE 有权
标题翻译：用于控制通过流体通道，装置和多路阀装置的流体流动的阀装置
公开(公告)号：US20130118619A1
公开(公告)日：2013-05-16
申请号：US13701312
申请日：2011-06-01
申请人： Andreas Loth , Florian Bühs
发明人： Andreas Loth , Florian Bühs
IPC分类号： A61M39/28 , A61M39/22
CPC分类号： A61M39/284 , A61M37/0076 , A61M39/223 , A61M2039/226 , F16K7/045 , Y10T137/86493
摘要： The invention relates to a valve device for controlling a flow of a fluid through a fluid channel, having a tube (2) made of a flexible material, in which a section of a fluid channel is formed, a valve component (1) assigned to the tube (2), a cantilevered arm (8), which is designed to be reversibly displaceable on the valve component (1) against a restoring force supplied at least partially by the cantilevered arm (8) itself, a squeeze element (10), which is arranged on a distal end of the cantilevered arm (8) for support of the cantilevered arm (8) on the valve component (1) and is configured to control a flow of a fluid through the fluid channel by pressing against an outside surface of the tube (2), optionally up to the closing of the fluid channel, and an actuator (11) which is configured to displace the squeeze element (10) in various control directions against the restoring force on the cantilevered arm (8), so that the pressure of the squeeze element (10) on the outside surface of the tube (2) and thereby the flow through the fluid channel can be regulated. In addition, the invention also relates to a system having at least one valve device and a pressure-applying device as well as a multi-way valve device having multiple valve devices.
摘要翻译：本发明涉及一种用于控制通过流体通道的流体流动的阀装置，其具有由柔性材料制成的管（2），其中形成有流体通道的一部分，阀组件（1）分配给管（2），悬臂（8），其被设计成可抵抗由悬臂（8）本身提供至少部分地提供的恢复力而在阀部件（1）上可逆地移位;挤压元件（10），其布置在悬臂（8）的远端上，用于支撑在阀部件（1）上的悬臂（8），并且构造成通过压靠外部来控制流体通过流体通道的流动管（2）的表面，可选地直到流体通道的关闭;以及致动器（11），其构造成克服悬臂（8）上的恢复力在各种控制方向上移动挤压元件（10），使挤压元件（10）在外表面上的压力（2），从而可以调节通过流体通道的流动。此外，本发明还涉及具有至少一个阀装置和施压装置的系统以及具有多个阀装置的多通阀装置。

9. 发明授权

US5294022A Fluid dispenser with a magnetically operable discharge opening 失效
标题翻译：具有磁力可操作的排放口的流体分配器
公开(公告)号：US5294022A
公开(公告)日：1994-03-15
申请号：US18625
申请日：1993-02-17
申请人： Anthony Earle
发明人： Anthony Earle
IPC分类号： B67D3/00 , B67D3/04 , F16K7/04 , G03D3/06 , B67D5/08
CPC分类号： F16K7/045 , B67D3/0003 , B67D3/041 , G03D3/065 , Y10S141/01
摘要： A fluid dispenser comprises an open-topped flexible container (13) which tapers downwardly to a discharge opening (14). The container (13) is mounted on a load platform (11) of a load cell (10). The portion of the container (13) that forms the discharge opening (14) is between one permanent magnet (16) on the load platform (11) and another permanent magnet (17) which is fixed to the material of the container (13). The magnets (16 and 17) attract one another to close the discharge opening (14). An electro-magnetic actuator (18), spaced from the magnet (17), is operable on command from a computer (12) to attract the magnet (17) and open the discharge opening (14). The computer (12) controls a shut-off valve (18) to control filling of the container (13) in accordance with the weight read out from the load cell (10).
摘要翻译：流体分配器包括朝向排放口（14）向下逐渐变细的敞开的柔性容器（13）。容器（13）安装在测力传感器（10）的负载平台（11）上。形成排出口（14）的容器（13）的一部分位于负载平台（11）上的一个永磁体（16）和固定在容器（13）的材料上的另一个永磁体之间，。磁体（16和17）彼此吸引以关闭排出口（14）。与磁体（17）间隔开的电磁致动器（18）可以根据来自计算机（12）的指令进行操作，以吸引磁体（17）并打开排放开口（14）。计算机（12）控制关闭阀（18），以根据从测力传感器（10）读出的重量来控制容器（13）的填充。

10. 发明授权

US5190071A Pinch valve assembly 失效
标题翻译：夹管阀组件
公开(公告)号：US5190071A
公开(公告)日：1993-03-02
申请号：US656241
申请日：1991-02-14
申请人： Akos Sule
发明人： Akos Sule
IPC分类号： F16K7/04
CPC分类号： F16K7/045 , Y10T137/8242 , Y10T137/8275 , Y10T137/87161
摘要： A pinch valve assembly includes a valve body in which a plunger is spring loaded against a portion of a flexible tube which passes through the valve body. The plunger causes the flexible tube to collapse preventing flow through the tube. Energization of a solenoid which is mounted on the valve body causes the plunger to release the tube, permitting flow. In an alternative embodiment, energization of the solenoid causes the plunger to bear on the flexible tube thereby providing a normally open valve arrangement.In another alternative embodiment the plunger bears on a plurality of flexible tubes thereby facilitating simultaneous control of different fluids.In still another alternative embodiment the plunger is mounted in roller bearings and the top of the plunger bears on an electrical switch contact which provides an electrical verification of the open or closed state of the pinch valve assembly.
摘要翻译：夹紧阀组件包括阀体，其中柱塞弹簧加载抵靠通过阀体的柔性管的一部分。柱塞导致柔性管塌陷，防止流经管。安装在阀体上的螺线管的通电导致柱塞释放管，允许流动。在替代实施例中，螺线管的通电使得柱塞承受在柔性管上，从而提供常开的阀装置。在另一替代实施例中，柱塞承载在多个柔性管上，从而便于同时控制不同的流体。在又一替代实施例中，柱塞安装在滚子轴承中，并且柱塞的顶部承载在电开关触点上，该电开关触点提供夹紧阀组件的打开或关闭状态的电气验证。

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