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1. 发明申请

US20170335265A1 TEMPERATURE CONTROL APPARATUS 审中-公开
公开(公告)号：US20170335265A1
公开(公告)日：2017-11-23
申请号：US15524715
申请日：2015-10-22
申请人： XYLEM IP MANAGEMENT S.À R.L.
发明人： Wilfried Stiller , Ulrich Lüdersen , Eilert Balssen
IPC分类号： C12M1/107 , C12M1/02 , C12M1/00 , C12M3/00 , C12M1/06
CPC分类号： C12M21/04 , C12M23/46 , C12M23/54 , C12M27/02 , C12M27/06 , C12M27/18 , C12M41/24 , Y02E50/343
摘要： A tempering device for tempering of biomass contained in a container, including at least one tempering mechanism, and at least one conveying device for conveying a mass flow of biomass in a main flow direction. The at least one conveying device includes at least one agitator, and wherein the at least one tempering mechanism is arranged in the main flow direction generated by the at least one conveying device. The at least one tempering mechanism is tubular with an inner tube and with an outer tube arranged coaxially to the inner tube. The inner tube and the outer tube form an intermediate space through which a tempering medium may flow. The tempering mechanism is oriented relative to the conveying device such that, in operation of the heating device, at least 40% of the delivery volume of the mass flow generated by the conveying device flows through the inner tube.

2. 发明授权

US09353343B2 Cell culture and gradient migration assay methods and devices 有权
标题翻译：细胞培养和梯度迁移测定方法和装置
公开(公告)号：US09353343B2
公开(公告)日：2016-05-31
申请号：US14081314
申请日：2013-11-15
申请人： EMD Millipore Corporation
发明人： Ju-Sung Paul Hung , Philip J. Lee , Amedeo J. Cappione
IPC分类号： C12Q1/02 , C12M1/00 , C12M3/06 , C12M1/34
CPC分类号： C12M23/16 , B01L3/502715 , B01L3/502753 , B01L2200/027 , B01L2200/0647 , B01L2200/0694 , B01L2300/0681 , B01L2300/0877 , B01L2300/14 , C12M23/34 , C12M23/40 , C12M27/18 , C12M29/10 , C12M41/46 , C12Q1/02 , C12Q1/025
摘要： A number of novel improved microfluidic configurations and systems and methods of manufacture and operation for a microfluidic invasion assay system.
摘要翻译：许多新颖的改进的微流体配置和用于微流体入侵测定系统的制造和操作的系统和方法。

3. 发明申请

US20140193853A1 BIOPROCESSING 有权
标题翻译：生物学
公开(公告)号：US20140193853A1
公开(公告)日：2014-07-10
申请号：US14196589
申请日：2014-03-04
申请人： Xyleco, Inc.
发明人： Marshall Medoff , Thomas Craig Masterman
IPC分类号： C12P19/14 , C12P19/02
CPC分类号： C12M29/12 , B01F3/04106 , B01F3/04539 , B01F3/04609 , B01F5/0212 , B01F5/0231 , B01F5/10 , B01F15/0022 , B01F15/00389 , B01F15/00396 , B01F2215/0073 , B01F2215/0463 , B01F2215/0481 , C12M27/00 , C12M27/02 , C12M27/18 , C12M29/00 , C12M29/06 , C12M29/22 , C12M33/00 , C12M41/02 , C12M41/12 , C12M41/26 , C12M41/28 , C12M41/32 , C12M41/34 , C12M41/46 , C12M41/48 , C12P19/02 , C12P19/14
摘要： Bioreactors are provided that include a vessel and a jet mixer disposed in the vessel. Methods that utilize the bioreactors are provided, involving placing a microorganism or cells and a fluid medium in the bioreactor.
摘要翻译：提供了包括设置在容器中的容器和喷射混合器的生物反应器。提供了利用生物反应器的方法，包括将微生物或细胞和流体介质置于生物反应器中。

4. 发明申请

US20140178980A1 Systems and Methods of Improved Fermentation 有权
标题翻译：改进发酵的系统和方法
公开(公告)号：US20140178980A1
公开(公告)日：2014-06-26
申请号：US14136852
申请日：2013-12-20
申请人： Colorado Energy Research Technologies, LLC.
发明人： Wayne J. Powell , Robert D. Boehmer , Lee L. Johnson
IPC分类号： C12M1/42
CPC分类号： C12M35/02 , C12M27/18 , C12M27/24
摘要： Devices, systems and methods for processing cellulosic material to produce fermentable sugars are provided. Devices, systems and methods for increasing fermentation rates of microbes via biostimulation are provided. Electrodes are preferably positioned along an interior or exterior of a tube-shaped component to administer electromagnetic/electric pulses to a solution comprising a microbe. Systems can advantageously be used in new biofuels production plants, or in existing biofuels production plants without the need for significant retrofits.
摘要翻译：提供了用于处理纤维素材料以产生可发酵糖的装置，系统和方法。提供了通过生物刺激提高微生物发酵速率的装置，系统和方法。电极优选沿着管状部件的内部或外部定位，以向包含微生物的溶液施加电磁/电脉冲。系统可以有利地用于新的生物燃料生产工厂，或在现有的生物燃料生产工厂中，而不需要重大的改造。

5. 发明申请

US20130171682A1 Cell Culture and Gradient Migration Assay Methods and Devices 有权
标题翻译：细胞培养和梯度迁移测定方法和装置
公开(公告)号：US20130171682A1
公开(公告)日：2013-07-04
申请号：US13761130
申请日：2013-02-06
申请人： EMD Millipore Corporation
发明人： Ju-Sung Paul Hung , Philip J. Lee , Amedeo J. Cappione, III
IPC分类号： C12Q1/02 , C12M3/06
CPC分类号： C12M23/16 , B01L3/502715 , B01L3/502753 , B01L2200/027 , B01L2200/0647 , B01L2200/0694 , B01L2300/0681 , B01L2300/0877 , B01L2300/14 , C12M23/34 , C12M23/40 , C12M27/18 , C12M29/10 , C12M41/46 , C12Q1/02 , C12Q1/025
摘要： A number of novel improved microfluidic configurations and systems and methods of manufacture and operation for a microfluidic invasion assay system.
摘要翻译：许多新颖的改进的微流体配置和用于微流体入侵测定系统的制造和操作的系统和方法。

6. 发明申请

US20120252103A1 APPARATUS, METHOD AND SYSTEM FOR ALGAE GROWTH 审中-公开
标题翻译：装置，方法和系统的生长
公开(公告)号：US20120252103A1
公开(公告)日：2012-10-04
申请号：US13501689
申请日：2010-10-27
申请人： Arthur Deane
发明人： Arthur Deane
IPC分类号： C12N1/12 , C12M1/42
CPC分类号： A01G33/00 , A01H4/001 , C12M21/02 , C12M23/22 , C12M23/34 , C12M27/00 , C12M27/18 , C12M31/10 , C12M41/00 , Y02A40/88
摘要： The cultivation, by optimized growth and harvesting of algae derived bio-mass may provide useful feedstock for various products and processes. The present invention provides an apparatus that allows for the optimized growth and harvesting of algae within a photo-bioreactor. The photo-bioreactor may include a channel and a propulsion unit for circulating an algae mixture through a channel while exposing the algae mixture to light to support photosynthesis and growth of the algae. A method is also provided for the optimizing the growth and harvesting of algae utilizing a number of different input streams. Further, a system including a programmable control assembly is provided for the growth and harvesting of algae.
摘要翻译：通过优化生长和收获藻类来源的生物质量的种植可以为各种产品和工艺提供有用的原料。本发明提供了允许在光生物反应器内优化生长和收获藻类的装置。光生物反应器可以包括通道和用于使藻类混合物循环通过通道的推进单元，同时将藻类混合物暴露于光以支持藻类的光合作用和生长。还提供了一种利用许多不同输入流优化藻类生长和收获的方法。此外，提供了包括可编程控制组件的系统用于藻类的生长和收获。

7. 发明申请

US20110039322A1 METHOD FOR PRODUCING BIOGAS 审中-公开
标题翻译：生物生物学方法
公开(公告)号：US20110039322A1
公开(公告)日：2011-02-17
申请号：US12680002
申请日：2008-09-22
申请人： Urs Inauen
发明人： Urs Inauen
IPC分类号： C12P5/02 , C12M3/02
CPC分类号： C12M23/56 , B01F13/0049 , B01F13/0052 , C12M21/04 , C12M27/18 , Y02E50/343
摘要： The invention relates to a method for producing biogas, wherein biomass (B) is filled into a biogas reactor (R), and a plurality of mixing bodies (1) is disposed on the biomass (B). The mixing bodies (1) float on the surface (O) of the biomass (B) and thereby dip partially into the biomass (B). The surface of the biomass is thus mixed, leading to an increase in the efficiency of gas yield.
摘要翻译：本发明涉及一种生产沼气的方法，其中生物质（B）被填充到生物气反应器（R）中，并且多个混合体（1）设置在生物质（B）上。混合体（1）漂浮在生物质（B）的表面（O）上，从而部分浸入生物质（B）中。因此生物质的表面被混合，导致气体产率的效率的提高。

8. 发明授权

US4378436A Process and device for improving the quality of mixing of liquid especially viscous media 失效
标题翻译：提高液体，特别是粘稠介质混合质量的工艺和装置
公开(公告)号：US4378436A
公开(公告)日：1983-03-29
申请号：US261195
申请日：1981-03-26
申请人： Helmut Heine , Karl Kuhn , Wolfgang Sittig
发明人： Helmut Heine , Karl Kuhn , Wolfgang Sittig
IPC分类号： B01F7/16 , C12M1/06 , C12N1/00 , C12M1/04 , C12M1/08
CPC分类号： B01F7/1675 , C12M27/08 , C12M27/18 , C12M41/22
摘要： The invention relates to a process for improving the quality of mixing of liquid especially viscous media in stirred tank reactors, wherein a change in direction of the medium set in motion is brought about at one point or at several points of the inner wall of the reactor at different levels, in a direction vertical to the angle of approaching flow (attack). The process is especially suitable for fermentation reactions.The invention moreover relates to a corresponding stirred tank reactor.
摘要翻译： PCT No.PCT / EP80 / 00093 Sec。 371日期：1981年5月8日 102（e）1981年3月26日PCT提交1980年9月5日PCT公布。第WO81 / 00722号公报日本1981年3月19日。本发明涉及一种提高搅拌釜反应器中液体特别是粘稠介质混合质量的方法，其中运动介质的方向变化在一点或几点的反应器内壁在垂直于接近流动（攻击）的角度的方向处于不同的水平。该方法特别适用于发酵反应。本发明还涉及相应的搅拌釜反应器。

9. 发明授权

US3740321A Cell propagator 失效
标题翻译：细胞传播器
公开(公告)号：US3740321A
公开(公告)日：1973-06-19
申请号：US3740321D
申请日：1970-04-15
申请人： SMITH KLINE FRENCH LAB
发明人： PAGANO J , VALENTA J
IPC分类号： C12M3/04 , C12K9/00
CPC分类号： C12M27/12 , C12M25/06 , C12M27/18
摘要： A CELL PROPAGATOR FOR ARTIFICALLY GROWING ANIMAL CELLS IN IN MONOLAYER CULTURES COMPRISES A PLASTIC ROLLER VESSEL CONTAINING A POROUS MASS O PLASTIC PROVIDING THE GROWTH SURFACE. THE CELL PROPAGATOR MAY, UNDER APPROPRIATE CONDITIONS, BE CONSIDERED DISPOSABLE. A FLUID-TIGHT SEAL IS PROVIDED, ALLOWING PH MONITORING, FEEDING, AERATION, SAMPLING AND HARVESTING THROUGH PROBES WHILE THE VESSEL IS ROTATING.

10. 发明申请

US20190247847A1 METHODS AND APPARATUS FOR PERFORMING METABOLIC MEASUREMENTS OF INDIVIDUAL CELL TYPES WITHIN NON-CONTACT CO-CULTURED SYSTEMS 审中-公开
公开(公告)号：US20190247847A1
公开(公告)日：2019-08-15
申请号：US15896255
申请日：2018-02-14
申请人： Agilent Technologies, Inc.
发明人： Chong Wing Yung , Genevieve Van De Bittner , Smruti Madan Phadnis
IPC分类号： B01L3/00 , C12M1/32 , C12M1/00 , C12M1/12 , C12M1/34 , G01N21/64
CPC分类号： B01L3/5025 , B01L3/50853 , B01L2200/026 , B01L2300/046 , B01L2300/0829 , C12M23/12 , C12M25/04 , C12M27/18 , C12M29/10 , C12M41/32 , G01N21/6454
摘要： The invention relates generally to methods and apparatus that measure one or more properties of an individual cell type in a non-contact co-culture. More specifically, the invention relates to a novel multiwell plate that allows separate but simultaneous metabolic measurements of cell populations in non-contact co culture.

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