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1. 发明授权

US11753423B2 Method for producing herbicide intermediate 有权
公开(公告)号：US11753423B2
公开(公告)日：2023-09-12
申请号：US17689178
申请日：2022-03-08
申请人： MMAG Co., Ltd. , National Institute of Advanced Industrial Science and Technology
发明人： Hirotaka Nagata , Nobuto Minowa , Nozomu Nakanishi , Katsuya Shimura , Tadahiro Fujitani
IPC分类号： C07F9/08
CPC分类号： C07F9/08
摘要： A method for producing methyldichlorophosphane, the method including: allowing methane and phosphorus trichloride to react in the presence of an additive using a metal compound, or a metal compound carried on a carrier, or both thereof.

2. 发明申请

US20190106632A1 BONDABLE FLAME-RETARDANT VANILLIN-DERIVED MOLECULES 审中-公开
公开(公告)号：US20190106632A1
公开(公告)日：2019-04-11
申请号：US16212954
申请日：2018-12-07
申请人： International Business Machines Corporation
发明人： Brandon M. Kobilka , Joseph Kuczynski , Jacob T. Porter , Jason T. Wertz
IPC分类号： C09K21/12 , C09K21/14 , C08K5/5317 , C08K5/5313 , C12P7/26 , C12P7/22 , C07F9/42 , C07F9/40 , C07F9/145 , C07F9/14 , C07F9/12 , C07F9/655 , C08K5/5337
CPC分类号： C09K21/12 , C07F9/08 , C07F9/12 , C07F9/1403 , C07F9/1406 , C07F9/145 , C07F9/4015 , C07F9/4021 , C07F9/425 , C07F9/65502 , C08K5/5313 , C08K5/5317 , C08K5/5337 , C09K21/14
摘要： A flame-retardant vanillin-derived molecule, a process for forming a flame-retardant resin, and an article of manufacture comprising a material that contains the flame-retardant vanillin-derived molecule are disclosed. The flame-retardant vanillin-derived molecule can be synthesized from vanillin obtained from a bio-based source, and can have at least one phosphoryl or phosphonyl moiety with phenyl, allyl, epoxide, propylene carbonate, or thioether substituents. The process for forming the flame-retardant resin can include reacting a vanillin derivative and a flame-retardant phosphorus-based molecule to form the flame-retardant vanillin-derived molecule, and binding the flame-retardant vanillin-derived molecule to a resin. The flame-retardant vanillin-derived molecules can also be bound to polymers. The material in the article of manufacture can be flame-retardant, and contain the flame-retardant vanillin-derived molecules. Examples of materials that can be in the article of manufacture can include resins, plastics, adhesives, polymers, etc.

3. 发明申请

US20170151375A1 BIOCOMPATIBLE, BIOMIMETIC AMPHOLYTE MATERIALS 审中-公开
公开(公告)号：US20170151375A1
公开(公告)日：2017-06-01
申请号：US15429835
申请日：2017-02-10
申请人： BioInteractions Ltd.
发明人： Fanny Burrows , John E. Mckendrick , Alan Rhodes , Simon J. Onis , Shivpal S. Sandhu
IPC分类号： A61L33/00 , C09D133/14 , C08F220/28 , G02B1/04 , A61L29/14 , A61L31/10 , A61L33/06 , C07F9/09 , A61L31/14 , C08F220/18 , A61L29/08
CPC分类号： A61L33/0023 , A61L27/34 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/064 , C07B2200/11 , C07F9/062 , C07F9/08 , C07F9/091 , C07F9/106 , C07F9/32 , C07F9/3205 , C07F9/36 , C07F9/40 , C07F9/4078 , C07F9/65742 , C08F8/30 , C08F8/40 , C08F16/14 , C08F18/22 , C08F30/02 , C08F116/14 , C08F122/02 , C08F130/02 , C08F216/14 , C08F220/18 , C08F220/28 , C08F222/02 , C08F230/02 , C08F2220/1825 , C08F2220/281 , C08F2220/285 , C09D133/14 , G02B1/043 , C08L33/26 , C08L33/10 , C08L33/12
摘要： New ampholyte biomaterial compounds containing ampholyte moieties are synthesized and integrated into polymeric assemblies to provide hydrophilic polymers exhibiting improved biocompatibility, haemocompatibility, hydrophilicity non-thrombogenicity, anti-bacterial ability, and mechanical strength, as well as suitability as a drug delivery platform.

4. 发明申请

US20130053470A1 BIOCOMPATIBLE, BIOMIMETIC AMPHOLYTE MATERIALS 有权
标题翻译：生物成分，生物活性胶体材料
公开(公告)号：US20130053470A1
公开(公告)日：2013-02-28
申请号：US13529708
申请日：2012-06-21
申请人： Fanny Raisin-Dadre , John E. Mckendrick , Alan Rhodes , Simon J. Onis , Shivpal S. Sandhu
发明人： Fanny Raisin-Dadre , John E. Mckendrick , Alan Rhodes , Simon J. Onis , Shivpal S. Sandhu
IPC分类号： C07F9/09 , B05D5/06 , B05D5/00 , C08F30/02 , C08L85/02
CPC分类号： A61L33/0023 , A61L27/34 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/064 , C07B2200/11 , C07F9/062 , C07F9/08 , C07F9/091 , C07F9/106 , C07F9/32 , C07F9/3205 , C07F9/36 , C07F9/40 , C07F9/4078 , C07F9/65742 , C08F30/02 , C08F122/02 , C08F130/02 , C08F220/18 , C08F220/28 , C08F222/02 , C08F230/02 , C08F2220/1825 , C08F2220/281 , C08F2220/285 , C09D133/14 , G02B1/043 , C08L33/26 , C08L33/10 , C08L33/12
摘要： New ampholyte biomaterial compounds containing ampholyte moieties are synthesized and integrated into polymeric assemblies to provide hydrophilic polymers exhibiting improved biocompatibility, haemocompatibility, hydrophilicity non-thrombogenicity, anti-bacterial ability, and mechanical strength, as well as suitability as a drug delivery platform.
摘要翻译：合成含有两性电解质部分的新的两性电解生物材料化合物并整合到聚合物组件中以提供表现出改进的生物相容性，血液相容性，亲水性，非血栓形成性，抗细菌能力和机械强度以及作为药物递送平台的适用性的亲水性聚合物。

5. 发明授权

US07745614B2 Universal linker compositions for the release or transfer of chemical agents from a polynucleotide 有权
标题翻译：用于从多核苷酸释放或转移化学试剂的通用接头组合物
公开(公告)号：US07745614B2
公开(公告)日：2010-06-29
申请号：US11218961
申请日：2005-09-01
申请人： Eric Todd Kool , Hiroshi Abe
发明人： Eric Todd Kool , Hiroshi Abe
IPC分类号： C07H21/02 , C07H19/04 , C12Q1/68 , C07H21/00 , C07F9/00
CPC分类号： C07F9/2429 , C07F9/08 , C07F9/2408 , Y10S977/792
摘要： A universal linker structure is provided, in which a functional group and activating leaving group are placed on a tether, allowing the placement of an electrophile at the end of any nucleic acid sequence. The electrophile on the tether can react with a second nucleic acid carrying a nucleophile when the two nucleic acids are hybridized near one another, resulting in release of the leaving group, and creation of a functional change. The linker can be designed to destabilize the ligation product without slowing the rate of reaction. This lowers product inhibition, and the target DNA or RNA can become a catalyst for isothermally generating multiple signals for detection. This enhanced signal is demonstrated in solution experiments and in solid supported assays. The universal linkers of the present invention are simple and inexpensive to prepare, and can be appended to any polynucleotide in automated steps on a standard DNA synthesizer.
摘要翻译：提供通用接头结构，其中功能基团和活化离去基团置于系链上，允许在任何核酸序列末端放置亲电子试剂。当两个核酸彼此相互杂交时，系链上的亲电子体可以与携带亲核试剂的第二核酸反应，导致离去基团的释放和功能变化的产生。连接体可以被设计成使连接产物不稳定而不减慢反应速率。这降低了产物抑制，目标DNA或RNA可以成为用于等温生成多个用于检测的信号的催化剂。在溶液实验和固体支持的测定中证明了这种增强的信号。本发明的通用接头是简单且廉价的制备，并且可以在标准DNA合成仪上以自动步骤附加到任何多核苷酸。

6. 发明申请

US20060199192A1 Universal linker compositions for the release or transfer of chemical agents from a polynucleotide 有权
标题翻译：用于从多核苷酸释放或转移化学试剂的通用接头组合物
公开(公告)号：US20060199192A1
公开(公告)日：2006-09-07
申请号：US11218961
申请日：2005-09-01
申请人： Eric Kool , Hiroshi Abe
发明人： Eric Kool , Hiroshi Abe
IPC分类号： C12Q1/68 , C07F9/02 , C07H19/04 , A61K48/00
CPC分类号： C07F9/2429 , C07F9/08 , C07F9/2408 , Y10S977/792
摘要： A universal linker structure is provided, in which a functional group and activating leaving group are placed on a tether, allowing the placement of an electrophile at the end of any nucleic acid sequence. The electrophile on the tether can react with a second nucleic acid carrying a nucleophile when the two nucleic acids are hybridized near one another, resulting in release of the leaving group, and creation of a functional change. The linker can be designed to destabilize the ligation product without slowing the rate of reaction. This lowers product inhibition, and the target DNA or RNA can become a catalyst for isothermally generating multiple signals for detection. This enhanced signal is demonstrated in solution experiments and in solid supported assays. The universal linkers of the present invention are simple and inexpensive to prepare, and can be appended to any polynucleotide in automated steps on a standard DNA synthesizer.
摘要翻译：提供通用接头结构，其中功能基团和活化离去基团置于系链上，允许在任何核酸序列末端放置亲电子试剂。当两个核酸彼此相互杂交时，系链上的亲电子体可以与携带亲核试剂的第二核酸反应，导致离去基团的释放和功能变化的产生。连接体可以被设计成使连接产物不稳定而不减慢反应速率。这降低了产物抑制，目标DNA或RNA可以成为用于等温生成多个用于检测的信号的催化剂。在溶液实验和固体支持的测定中证明了这种增强的信号。本发明的通用接头是简单且廉价的制备，并且可以在标准DNA合成仪上以自动步骤附加到任何多核苷酸。

7. 发明授权

US3966900A Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator 失效
标题翻译：蒸发器系统包括稳定的农药磷酸酯和用于稳定在蒸发器中封闭的酯的方法
公开(公告)号：US3966900A
公开(公告)日：1976-06-29
申请号：US427103
申请日：1973-12-21
申请人： Claude Hennart , Bernard Rabussier , Jean-Pierre Mandon
发明人： Claude Hennart , Bernard Rabussier , Jean-Pierre Mandon
IPC分类号： A01N25/30 , C07F9/08 , C07F9/113 , C09B45/00 , A01N17/12 , A01N9/36
CPC分类号： C07C251/72 , C07F9/08 , C07F9/113 , C09B45/00
摘要： An evaporator system adapted for emitting insect killing vapors of an insecticide therefrom and comprising a liquid or solid composition enclosed therein, said insecticide consisting in at least one volatile phosphoric acid ester which is stabilized by at least one diazene compound.
摘要翻译：一种蒸发器系统，适用于从其中发射杀虫剂的昆虫杀伤蒸气并包括其中包含的液体或固体组合物，所述杀虫剂由至少一种由至少一种二氮烯化合物稳定的挥发性磷酸酯组成。

8. 发明授权

US3928505A Dipentaerythritol and pentaerythritol phosphite 失效
标题翻译：二季戊四醇和季戊四醇亚磷酸酯
公开(公告)号：US3928505A
公开(公告)日：1975-12-23
申请号：US51525474
申请日：1974-10-16
申请人： BORG WARNER
发明人： KLICKER JAMES D , COHEN MURRAY S
IPC分类号： C07F9/08 , C07F9/6574 , C08K5/524 , C07F9/15
CPC分类号： C07F9/08 , C07F9/6574 , C08K5/524
摘要： By reacting a mxiture of pentaerythritol and dipentaerythritol with a trihydrocarbyl or trihalohydrocarbyl phosphite, preferably triphenyl phosphite there is obtained pentaerythritoldipentaerythritol phosphite as a relatively low melting solid. In contrast to the use of only pentaerythritol or dipentaerythritol the product can be readily worked as a liquid above 110*C., e.g., 150*-160*C. Furthermore, the performance and physical properties of this product are not the same as that of an equal molar mixture of pure pentaerythritol phosphite and dipentaerythritol phosphite.
摘要翻译：通过使季戊四醇和二季戊四醇与三烃基或三卤代烃基亚磷酸酯反应，优选亚磷酸三苯酯，得到季戊四醇 - 二季戊四醇亚磷酸酯作为相对低熔点的固体。与仅使用季戊四醇或二季戊四醇相反，该产品可以容易地作为高于110℃，例如150-116℃的液体加工。此外，该产品的性能和物理性质与该产品的性能和物理性质不同纯的季戊四醇亚磷酸酯和二季戊四醇亚磷酸酯的等摩尔混合物。

9. 发明授权

US3790649A Preparation of esters of phosphorus acids 失效
标题翻译：磷酸酯的制备
公开(公告)号：US3790649A
公开(公告)日：1974-02-05
申请号：US3790649D
申请日：1971-06-24
申请人： SCHUMACHER I , BAKER J
发明人： SCHUMACHER I , BAKER J
IPC分类号： C07F9/08 , C07F9/16
CPC分类号： C07F9/08 , C07F9/16
摘要： HALOGEN-CONTAINING ESTERS OF PHOSPHORUS ACIDS ARE PREPARED BY AN IMPROVED PROCESS WHEREBY THIOL- OR HYDROXYLCONTAINING ORGANIC MATERIALS AND PHOSPHORUS HALIDES ARE REACTED AT SPECIFIED TEMPERATURES IN THE PRESENCE OF A DISTILLATION RESIDUE, PRODUCED BY DISTILLING (A) THE PRODUCT DERIVED FROM A REACTION MIXTURE OF A THIOL- OR HYDROXYLCONTAINING ORGANIC MATERIAL, A PHOSPHORUS HALIDE AND A CATALYST MATERIAL SELECTED FROM AMIDE, PHOSPHORUS AMIDE, UREA AND AMMONIUM SALT COMPOUNDS CONTAINING A NITROGEN ATOM CAPABLE OF FORMING A COMPLEX WITH A PHOSPHORUS MOIETY OR (B) THE PRODUCT DERIVED FROM SUCH REACTION MIXTURE IN WHICH SAID DISTILLATION RESIDUE IS EMPLOYED AS THE CATALYST MATERIAL, THEREBY PROVIDING HIGH YIELDS OF SUBSTANTIALLY PURE ESTERS AND ALLOWING PREPARATION OF SELECTED HALOGEN-CONTAINING MONO- AND DI-ESTERS OF PHOSPHORUS ESTERS HAVING SUBSTANTIALLY NO SIDE REACTANT CONTAMINATION. THE PHOSPHORUS ESTERS ARE USEFUL AS INTERMEDIATES IN THE PREPARATION OF PLASTICIZERS, OIL ADDITIVES AND FUNCTIONAL FLUIDS.

10. 发明授权

US3755250A Phenolic phosphate and phosphite antioxidants 失效
标题翻译：苯酚磷酸盐和磷酸盐抗氧化剂
公开(公告)号：US3755250A
公开(公告)日：1973-08-28
申请号：US3755250D
申请日：1972-04-20
申请人： ETHYL CORP
发明人： WOLLENSAK J , ZAWESKI E
IPC分类号： C07F9/08 , C07F9/12 , C07F9/18 , C07F9/205 , C08K5/5398 , C09K15/32 , C10M137/02 , C10M137/04 , C10M137/10 , C08F45/58 , C08G51/58
CPC分类号： C10M137/105 , C07F9/08 , C07F9/12 , C07F9/18 , C07F9/205 , C08K5/5398 , C09K15/32 , C09K15/322 , C09K15/324 , C10M137/02 , C10M137/04 , C10M2205/026 , C10M2207/027 , C10M2207/028 , C10M2207/125 , C10M2207/129 , C10M2207/281 , C10M2207/282 , C10M2207/283 , C10M2207/284 , C10M2207/285 , C10M2207/286 , C10M2207/34 , C10M2209/084 , C10M2219/024 , C10M2219/044 , C10M2219/046 , C10M2219/085 , C10M2219/087 , C10M2219/088 , C10M2219/089 , C10M2223/04 , C10M2223/042 , C10M2223/045 , C10M2223/047 , C10M2229/041 , C10N2210/00 , C10N2210/02 , C10N2210/03 , C10N2220/02 , C10N2240/08 , C10N2240/14 , C10N2250/10 , Y10S524/925
摘要： Organic material, especially polypropylene, is stabilized by the addition of mono- or di- (dihydrocarbyl-hydroxyphenyl) alkyl phosphates, phosphites, thiophosphates or thiophosphites, such as 3,5-di-tert-butyl-4-hydroxyphenyl di-n-octadecyl phosphate. Effectiveness is synergistically improved by inclusion of a dialkyl thiodialkanoate such as dilaurylthiodipropionate.
摘要翻译：通过加入单或二（二烃基 - 羟基苯基）烷基磷酸酯，亚磷酸酯，硫代磷酸酯或硫代亚磷酸酯，例如3,5-二 - 叔丁基-4-羟基苯基二 - 磷酸十八烷基酯通过包含硫代二丙酸二月桂酯等硫代二烷基二烷基酯来协同增效。

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