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1. 发明申请

US20150313996A1 COMPOSITION FOR STABILIZING FUSION PROTEIN IN WHICH PROTEIN AND FC DOMAIN ARE FUSED 有权
标题翻译：用于稳定蛋白质和FC域的融合蛋白的组合物被融合
公开(公告)号：US20150313996A1
公开(公告)日：2015-11-05
申请号：US14439644
申请日：2013-10-23
申请人： ALTEOGEN INC.
发明人： Soon Jae Park , Seong-Kyu Kim
IPC分类号： A61K47/02 , C01C1/16 , C09K15/20 , C07K14/705
CPC分类号： A61K47/02 , A61K9/08 , A61K38/1793 , A61K47/26 , C01C1/164 , C07K14/70578 , C07K2319/30 , C09K15/20
摘要： The present invention relates to a composition for stabilizing a fusion protein of a physiologically active protein and an Fc domain, and more particularly to a method of stabilizing a fusion protein of a protein and an Fc domain using a composition containing an ammonium salt or a combination of an ammonium salt and succinate. The composition containing an ammonium salt or a combination of an ammonium salt and succinate according to the present invention can effectively inhibit the aggregation of the protein-Fc domain fusion protein, and thus enables the fusion protein to be stored for a long period of time. Accordingly, the composition can be widely used in the medical field that uses the protein-Fc domain fusion protein.
摘要翻译：本发明涉及用于稳定生理活性蛋白质和Fc结构域的融合蛋白质的组合物，更具体地涉及使用含有铵盐或组合物的组合物来稳定蛋白质和Fc结构域的融合蛋白的方法的铵盐和琥珀酸盐。含有本发明铵盐或铵盐和琥珀酸盐的组合的组合物能够有效地抑制蛋白质-Fc结构域融合蛋白质的聚集，能够使融合蛋白质长时间保存。因此，该组合物可广泛用于使用蛋白质 - Fc结构域融合蛋白的医疗领域。

2. 发明授权

US09174850B2 Gaseous ammonia removal method 有权
标题翻译：气态氨去除法
公开(公告)号：US09174850B2
公开(公告)日：2015-11-03
申请号：US14528614
申请日：2014-10-30
申请人： The United States of America, as represented by the Secretary of Agriculture
发明人： Ariel A Szogi , Matias B Vanotti , Michael J Rothrock
IPC分类号： C01C1/242 , C01C1/28 , B01D53/22 , C01C1/16 , C01C1/18 , C07C51/41 , C01C1/12
CPC分类号： C01C1/28 , B01D53/22 , B01D2251/50 , B01D2251/70 , B01D2257/406 , B01D2258/0266 , B01D2258/06 , C01C1/12 , C01C1/164 , C01C1/185 , C01C1/242 , C07C51/412 , C07C59/265 , C07C55/07 , C07C59/08
摘要： A system and method for passive capture of ammonia in an enclosure containing material that gives off ammonia. The invention allows for the passage of gaseous NH3 through microporous hydrophobic gas-permeable membranes and its capture in a circulated acidic solution with concomitant production of a concentrated non-volatile ammonium salt.
摘要翻译：一种用于被动捕获氨的系统和方法，包含含有释放氨的物质的外壳。本发明允许气态NH 3通过微孔疏水气体渗透膜，并将其捕获在循环的酸性溶液中，伴随产生浓缩的非挥发性铵盐。

3. 发明授权

US08906332B2 Gaseous ammonia removal system 有权
标题翻译：气态除氨系统
公开(公告)号：US08906332B2
公开(公告)日：2014-12-09
申请号：US13048375
申请日：2011-03-15
申请人： Ariel A. Szogi , Matias B. Vanotti , Michael J. Rothrock
发明人： Ariel A. Szogi , Matias B. Vanotti , Michael J. Rothrock
IPC分类号： B01D53/34 , C01C1/242 , B01D53/22 , C07C51/41 , C01C1/16 , C01C1/28 , C01C1/18
CPC分类号： C01C1/28 , B01D53/22 , B01D2251/50 , B01D2251/70 , B01D2257/406 , B01D2258/0266 , B01D2258/06 , C01C1/12 , C01C1/164 , C01C1/185 , C01C1/242 , C07C51/412 , C07C59/265 , C07C55/07 , C07C59/08
摘要： A system and method for passive capture of ammonia in an enclosure containing material that gives off ammonia. The invention allows for the passage of gaseous NH3 through microporous hydrophobic gas-permeable membranes and its capture in a circulated acidic solution with concomitant production of a concentrated non-volatile ammonium salt.
摘要翻译：一种用于被动捕获氨的系统和方法，包含含有释放氨的物质的外壳。本发明允许气态NH 3通过微孔疏水气体渗透膜，并将其捕获在循环的酸性溶液中，伴随产生浓缩的非挥发性铵盐。

4. 发明申请

US20140341794A1 PROCESS FOR THE COUPLED PREPARATION OF POLYSILAZANES AND TRISILYLAMINE 审中-公开
标题翻译：多氯联苯和三甲硅烷偶联制备工艺
公开(公告)号：US20140341794A1
公开(公告)日：2014-11-20
申请号：US14212191
申请日：2014-03-14
申请人： Carl-Friedrich Hoppe , Christian Goetz , Hartwig Rauleder , Goswin Uehlenbruck
发明人： Carl-Friedrich Hoppe , Christian Goetz , Hartwig Rauleder , Goswin Uehlenbruck
IPC分类号： C01B21/087
CPC分类号： C01B21/087 , C01C1/164
摘要： The invention relates to a process for preparing trisilylamine and polysilazanes in the liquid phase, in which ammonia dissolved in an inert solvent is initially introduced in a substoichiometric amount relative to monochlorosilane which is likewise present in an inert solvent. The reaction is carried out in a reactor in which trisilylamine formed according to the following equation 4NH3+3H3SiCl→3NH4Cl+(SiH3)3N and polysilazanes are formed. The reactor is subsequently depressurized and TSA is separated off in gaseous form from the product mixture. The TSA obtained is purified by filtration and distillation and obtained in high or very high purity. Further ammonia dissolved in an inert solvent is subsequently introduced into the reactor, using, together with the previously introduced amount of ammonia, a stoichiometric excess of ammonia relative to the amount of MCS previously present. Excess ammonia is subsequently discharged, inert gas is introduced and the bottom product mixture from the reactor is passed through a filter unit, with solid ammonium chloride being separated off and a liquid mixture of polysilazanes and solvent being obtained.
摘要翻译：本发明涉及在液相中制备三甲胺和聚硅氮烷的方法，其中溶解在惰性溶剂中的氨相对于同样存在于惰性溶剂中的一氯硅烷，最初以亚化学计量的量引入。该反应在其中形成根据下列等式4NH 3 + 3H 3 SiCl→3NH 4 Cl +（SiH 3）3 N和聚硅氮烷形成的三乙胺的反应器中进行。随后将反应器减压，并将TSA从产物混合物中分离出气态。通过过滤和蒸馏纯化获得的TSA，得到高纯度或非常高的纯度。随后将溶解在惰性溶剂中的氨加入到反应器中，与先前导入的氨一起使用相对于先前存在的MCS的量的化学计量过量的氨。随后排出过多的氨，引入惰性气体，将来自反应器的底部产物混合物通过过滤器单元，分离固体氯化铵，得到聚硅氮烷和溶剂的液体混合物。

5. 发明申请

US20140199227A1 PRODUCTION OF TRISILYLAMINE FROM MONOCHLOROSILANE AND AMMONIA BY USE OF INERT SOLVENT 有权
标题翻译：通过使用惰性溶剂从单氯氰酸盐和氨水生产三甲苯胺
公开(公告)号：US20140199227A1
公开(公告)日：2014-07-17
申请号：US14212341
申请日：2014-03-14
申请人： Carl-Friedrich Hoppe , Hartwig Rauleder , Christian Goetz
发明人： Carl-Friedrich Hoppe , Hartwig Rauleder , Christian Goetz
IPC分类号： C01B21/087
CPC分类号： C01B21/087 , C01C1/164
摘要： The present invention relates to a specific process for producing trisilylamine from monochlorosilane and ammonia in the liquid phase. The invention further relates to a plant wherein such a process can be carried out with advantage.
摘要翻译：本发明涉及在液相中由一氯硅烷和氨制备三甲胺的具体方法。本发明还涉及一种可以有利地进行这种方法的设备。

6. 发明申请

US20140161705A1 PROCESS FOR THE PREPARATION OF TRISILYLAMINE FROM MONOCHLOROSILANE AND AMMONIA 有权
标题翻译：从单氯氰菊酯和氨基磺酸制备三甲苯胺的方法
公开(公告)号：US20140161705A1
公开(公告)日：2014-06-12
申请号：US14131126
申请日：2012-05-15
申请人： Carl-Friedrich Hoppe , Hartwig Rauleder , Ingrid Lunt-Rieg , Christian Goetz
发明人： Carl-Friedrich Hoppe , Hartwig Rauleder , Ingrid Lunt-Rieg , Christian Goetz
IPC分类号： C01B21/087 , B01J19/24
CPC分类号： C01B21/087 , B01J19/24 , C01B33/043 , C01C1/164
摘要： The present invention relates to a specific process for producing trisilylamine from monochlorosilane and ammonia in the liquid phase. The invention further relates to a plant in which such a process can be carried out with advantage.
摘要翻译：本发明涉及在液相中由一氯硅烷和氨制备三甲胺的具体方法。本发明还涉及可以有利地进行这种方法的设备。

7. 发明申请

US20100247413A1 LUMINESCENT SAMARIUM-DOPED TITANIUM DIOXIDE 审中-公开
标题翻译： LUMINESCENT SAMARIUM DOPED TITANIUM DIOXIDE
公开(公告)号：US20100247413A1
公开(公告)日：2010-09-30
申请号：US12744213
申请日：2008-12-18
申请人： Carmine Torardi
发明人： Carmine Torardi
IPC分类号： C01F17/00
CPC分类号： C09K11/7759 , B82Y30/00 , C01C1/16 , C01C1/164 , C01G23/0536 , C01G25/02 , C01G27/02 , C01P2002/54 , C01P2002/72 , C01P2002/84 , C01P2004/03 , C01P2004/50 , C01P2004/64 , C01P2006/12 , C01P2006/14 , C01P2006/16
摘要： This disclosure relates to a process for making luminescent titanium dioxide, comprising: precipitating a halide salt and a hydrolyzed compound comprising titanium from a reaction mixture comprising a source of samarium, a titanium starting material selected from the group consisting of titanium tetrachloride, titanium oxychloride, and mixtures thereof, a base selected from the group consisting of ammonium hydroxide, ammonium carbonate, ammonium bicarbonate, tetramethyl ammonium hydroxide or tetraethyl ammonium hydroxide or mixture thereof, and a solvent selected from the group consisting of ethanol, n-propanol, i-propanol, dimethyl acetamide, alcoholic ammonium halide and aqueous ammonium halide and mixtures thereof to form a precipitate; and removing the halide salt from the precipitate to recover a samarium-doped oxide of titanium.
摘要翻译：本公开涉及一种制备发光二氧化钛的方法，包括：从包含钐源的反应混合物中沉淀卤化物盐和包含钛的水解化合物，选自四氯化钛，氯氧化钛，和它们的混合物，选自氢氧化铵，碳酸铵，碳酸氢铵，四甲基氢氧化铵或四乙基氢氧化铵或其混合物的碱和选自乙醇，正丙醇，异丙醇的溶剂二甲基乙酰胺，醇卤化铵和卤化铵水溶液及其混合物形成沉淀物; 并从沉淀物中除去卤化物盐以回收掺钐氧化物的钛。

8. 发明授权

US07070751B2 Production of gaseous chloramine 失效
标题翻译：生产气态氯胺
公开(公告)号：US07070751B2
公开(公告)日：2006-07-04
申请号：US10713996
申请日：2003-11-14
申请人： Srinivas Tummala , Shun Wang Leung , Ehrlic T. Lo , Mario Moisés Alvarez
发明人： Srinivas Tummala , Shun Wang Leung , Ehrlic T. Lo , Mario Moisés Alvarez
IPC分类号： C01B21/083
CPC分类号： C01C1/164 , B01J4/001 , B01J12/00 , B01J2219/0254 , B01J2219/0286 , C01B21/091
摘要： The present invention provides a reactor for the gas-phase reaction of commercially available gases in the presence of an inert carrier gas to form product gas. The reactor has a streamlined, compact configuration and at least one solids collection and removal system downstream of the reactor, where solids are efficiently removed from the product gas stream, leaving high purity product gas. The removal system allows for a simple reactor design, which is easy to clean and operates continuously over longer periods of time.
摘要翻译：本发明提供了一种用于在惰性载气存在下商业上可获得的气体进行气相反应以形成产物气体的反应器。反应器具有流线型，紧凑的构造和在反应器下游的至少一个固体收集和去除系统，其中固体从产物气流中有效地除去，留下高纯度的产物气体。拆卸系统允许简单的反应器设计，其易于清洁并且在更长的时间段内连续操作。

9. 发明授权

US6051729A Process for preparing organosilazanes 失效
标题翻译：制备有机硅氮烷的方法
公开(公告)号：US6051729A
公开(公告)日：2000-04-18
申请号：US177941
申请日：1998-10-23
申请人： Richard Weidner , Walter Benischke , Gunther Uhlendorf
发明人： Richard Weidner , Walter Benischke , Gunther Uhlendorf
IPC分类号： C01C1/16 , C07F7/10 , G07F7/10
CPC分类号： C01C1/164 , C07F7/10
摘要： A process for preparing organosilazane and ammonium chloride, by reaction of an organochlorosilane with ammonia in the presence of organosilazane as solvent, wherein ammonium chloride is removed from the resulting organosilazane and ammonium chloride-containing mixture, the improvement comprising adding an antiblocking agent to the mixture before removal, or to the ammonium chloride after its removal, such that a non-blocking, reusable ammonium chloride product is obtained.
摘要翻译：通过有机氯硅烷与氨在有机硅氮烷作为溶剂的存在下反应制备有机硅氮烷和氯化铵的方法，其中从得到的有机硅氮烷和含氯化铵混合物中除去氯化铵，其改进包括向混合物中加入防粘连剂在除去之前，或在氯化铵除去之后，得到非阻塞的可重复使用的氯化铵产物。

10. 发明授权

US3647367A Method for making anhydrous magnesium chloride 失效
标题翻译：制造无水氯化镁的方法
公开(公告)号：US3647367A
公开(公告)日：1972-03-07
申请号：US3647367D
申请日：1969-12-29
申请人： PETE PRESTININNI , RUTH G MACEY , ANN M MACEY , MACEY JAMES G
发明人： MACEY JAMES G
IPC分类号： C01C1/16 , C01F5/30
CPC分类号： C01C1/164 , C01F5/30
摘要： Anhydrous purified magnesium chloride is made from anhydrous ammonium carnallite in a specially adapted apparatus by decomposing the anhydrous ammonium carnallite in the substantial absence of contaminants, employing superheated molten magnesium chloride as the heating source, ammonium chloride vapor and molten magnesium chloride being recovered separately, and any residual magnesium oxide being precipitated from the molten magnesium chloride.
摘要翻译：无水纯化氯化镁由无水氯化钙制成，在特别适用的装置中，通过使用过热熔融氯化镁作为加热源，基本上不存在污染物，分解回收氯化镁蒸气和熔融氯化镁，分解回收无水氯碳酸钙，从熔融氯化镁中沉淀出残留的氧化镁。

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