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    • 9. 发明申请
    • Metal wire with filaments for biomedical applications
    • 金属丝与细丝用于生物医学应用
    • US20060143906A1
    • 2006-07-06
    • US11337982
    • 2006-01-24
    • David Bradley
    • David Bradley
    • H01R43/00
    • B23P15/00A61F2250/0067A61F2250/0068A61F2250/0098B21C1/003B21C37/042B21C37/045B21F45/008Y10T29/49117Y10T29/4981Y10T29/49885Y10T29/49925Y10T29/49927Y10T29/49982Y10T29/49986
    • A method for constructing a metal wire with embedded filaments or cavities therein for biomedical applications. The method includes first drilling nonconcentric apertures in a symmetrical pattern in a metal rod and then embedding filaments in the apertures. The metal rod is then drawn and thermally-treated to form a metal wire with embedded filaments therein. The filaments may advantageously provide fatigue resistance, radiopacity, and electrical conductance to the metal wire. The method optionally provides an additional step for withdrawing or removing the filaments using various methods to create cavities for cavity access within the metal wire. The metal wire may be finished to provide access to the cavities or filaments embedded therein. The cavities may then be filled with a therapeutic drug for elution inside the human body or used for passage of body fluids. An optional biocompatible coating may be disposed around the metal wire to prevent escape of the therapeutic drug before insertion into the human body. The cavities may also be filled with different materials as compared to the original filaments.
    • 一种用于构建其中具有嵌入的细丝或空腔的金属线的方法,用于生物医学应用。 该方法包括首先在金属棒中以对称图案钻出非同心孔,然后将细丝嵌入孔中。 然后将金属棒拉伸并热处理以形成其中具有嵌入的细丝的金属线。 长丝可以有利地提供对金属丝的耐疲劳性,不透射线性和导电性。 该方法可选地提供了用于使用各种方法抽出或去除长丝的附加步骤,以在金属丝内产生用于空腔进入的空腔。 金属丝可以被完成以提供对嵌入其中的空腔或细丝的接近。 然后可以用用于在人体内洗脱或用于体液通过的治疗药物填充空腔。 可选的生物相容性涂层可以设置在金属丝周围,以防止治疗药物在插入人体内之前逸出。 与原始细丝相比,空腔也可以填充不同的材料。