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1. 发明申请

US20180326371A1 Method for Producing Emulsion 审中-公开
公开(公告)号：US20180326371A1
公开(公告)日：2018-11-15
申请号：US16040452
申请日：2018-07-19
申请人： Shigeru DEGUCHI , Nao IFUKU
发明人： Shigeru DEGUCHI , Nao IFUKU
IPC分类号： B01F3/08 , B01F17/00 , B01F3/00
CPC分类号： B01F3/0815 , B01F17/00 , B01F2003/0064
摘要： The disclosed invention is device for preparation of an emulsion and a method for producing an emulsion. The method comprises the steps of: (1) causing water and a water-insoluble substance that is to be emulsified to become freely miscible under conditions of temperature and pressure in the vicinity of the vapor-liquid critical point of water; and (2) cooling the product comprised of the water-insoluble substance and water solved each other in the presence of a surfactant to obtain a liquid comprised of the water-insoluble substance dispersed in water or a liquid comprised of water dispersed in the water-insoluble substance. The present invention provides a new device and a new method for producing emulsions with high efficiency without requiring a long period of processing or a great amount of energy.

2. 发明授权

US09962717B1 Instrument for automated sample preparation by combination homogenization and clarification 有权
公开(公告)号：US09962717B1
公开(公告)日：2018-05-08
申请号：US15665106
申请日：2017-07-31
申请人： MP Biomedicals, LLC
发明人： Miodrag Micic
IPC分类号： B04B5/10 , B01F11/00 , B01F3/08 , B01F3/20 , B04B1/14 , B04B1/20 , B04B9/10 , B04B15/12 , B04B9/08 , G01N1/28 , B01F3/12 , B01F3/00
CPC分类号： B04B5/10 , B01F3/0815 , B01F3/2071 , B01F11/0005 , B01F11/0028 , B01F2003/005 , B01F2003/0849 , B01F2003/1257 , B04B1/14 , B04B1/2016 , B04B5/0421 , B04B9/08 , B04B9/10 , B04B15/12 , G01N1/286 , G01N1/4077 , G01N2001/2866 , G01N2001/4083
摘要： Disclosed herein are instruments and methods for performing both sample homogenization and sample clarification by centrifugation with a single instrument without transferring the sample to a new sample container and without removing or repositioning the sample container within the instrument. In some embodiments, the instrument may automatically perform centrifugation after homogenization. In other embodiments, the instrument may perform both homogenization and centrifugation simultaneously.

3. 发明申请

US20160030951A1 PROGRAMMABLE FLUIDIC PROCESSORS 审中-公开
标题翻译：可编程流体加工器
公开(公告)号：US20160030951A1
公开(公告)日：2016-02-04
申请号：US14635293
申请日：2015-03-02
申请人： THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人： Peter R.C. Gascoyne , Jody Vykoukal , Jon Schwartz
IPC分类号： B03C5/02 , B01L3/00 , B01F13/00 , B03C5/00 , B01F3/08
CPC分类号： B03C5/026 , B01F3/0815 , B01F13/0003 , B01F13/0071 , B01F13/0076 , B01F13/0084 , B01L3/0268 , B01L3/502715 , B01L3/50273 , B01L3/502792 , B01L2200/06 , B01L2200/0605 , B01L2200/0673 , B01L2200/12 , B01L2200/14 , B01L2200/143 , B01L2300/0645 , B01L2300/0816 , B01L2300/0819 , B01L2300/089 , B01L2300/165 , B01L2300/166 , B01L2400/0424 , B03C5/005 , G01N2035/1034
摘要： Disclosed are apparatuses, systems, and methods for programmable fluidic processors. In one embodiment, the invention involves manipulating droplets across a reaction surface of the processor substantially contact-free of any surfaces. The reaction surface and the electrodes of the processor may include a coating repelling the droplets. Further, the present invention provides for a suitable suspending medium for repelling droplets away from fixed surfaces.
摘要翻译：公开了可编程流体处理器的装置，系统和方法。在一个实施例中，本发明涉及通过处理器的反应表面操纵液滴，其基本上与任何表面无接触。处理器的反应表面和电极可以包括排斥液滴的涂层。此外，本发明提供了用于将液滴从固定表面排出的合适的悬浮介质。

4. 发明申请

US20150144236A1 MODULAR INSTALLATION FOR THE MANUFACTURE OF AN EXPLOSIVE EMULSION PRECURSOR 有权
标题翻译：用于制造爆炸性乳液前体的模块化安装
公开(公告)号：US20150144236A1
公开(公告)日：2015-05-28
申请号：US14401347
申请日：2014-01-09
申请人： INTRATES & INNOVATION
发明人： James C. Eaton , Gilles Jauffret
IPC分类号： C06B47/14 , B01F15/06 , B01F3/08 , C06B31/00 , C06B21/00
CPC分类号： C06B47/14 , B01F1/0011 , B01F3/0815 , B01F7/00641 , B01F7/1665 , B01F7/18 , B01F15/06 , B01F15/066 , B01F2015/062 , C06B21/0008 , C06B31/00 , C06B47/145 , F28D1/0213 , F28D7/024 , F28D7/087 , F28F13/125
摘要： The present invention provides a modular installation (1) for carrying out a method of manufacturing an explosive emulsion precursor comprising at least three containers: —a first container (100) for preparing an aqueous phase, including a dissolution first tank (110); and —at least one second and/or third container (200, 300) including a second tank for preparing oily phase (210) and a third tank for preparing emulsion (310); and —at least one fourth and/or fifth container (400, 500) including means (410) for feeding heat and means (510) for feeding electrical energy; and —said first, second and/or third containers (100, 200, 300) being juxtaposed over at least a portion of one of their walls (100a, 300b, 200b) and being provided with openings (170, 370a, 275, 375, 270b) in their walls.
摘要翻译：本发明提供了一种用于执行制造包含至少三个容器的爆炸性乳液前体的方法的模块化装置（1）： - 用于制备水相的第一容器（100），包括溶解第一罐（110）; 和至少一个第二和/或第三容器（200,300），包括用于制备油相（210）的第二罐和用于制备乳液（310）的第三罐; 和至少一个第四和/或第五容器（400,500），包括用于馈送热量的装置（410）和用于馈送电能的装置（510）; 并且所述第一，第二和/或第三容器（100,200,300）并置在其一个壁（100a，300b，200b）的至少一部分上并且设置有开口（170,370a，275,375），270b）。

5. 发明授权

US08834722B2 Magnetic in-line purification of fluid 有权
标题翻译：磁流体在线净化
公开(公告)号：US08834722B2
公开(公告)日：2014-09-16
申请号：US13466868
申请日：2012-05-08
申请人： Angele Sjong
发明人： Angele Sjong
IPC分类号： B03C1/01 , B03C1/30 , B01F3/08 , B01F13/08 , B01F13/00 , B03C1/28
CPC分类号： B01F13/0059 , B01F3/0815 , B01F13/0006 , B01F13/0809 , B03C1/01 , B03C1/288 , B03C1/30 , B03C2201/32 , Y10T436/25375
摘要： Methods for in-line purification of surfactant from a first fluid, such as a microemulsion are disclosed. Magnetic particles coated with surfactant molecules may be used to bind surfactants from a fluid. A magnetic field may be used to separate the bound materials from the fluid.
摘要翻译：公开了从第一流体如微乳液中直接纯化表面活性剂的方法。涂有表面活性剂分子的磁性颗粒可用于从流体中结合表面活性剂。可以使用磁场将结合的材料与流体分离。

6. 发明申请

US20120152848A1 MAGNETIC IN-LINE PURIFICATION OF FLUID 有权
公开(公告)号：US20120152848A1
公开(公告)日：2012-06-21
申请号：US13121175
申请日：2010-12-21
申请人： Angele Sjong
发明人： Angele Sjong
IPC分类号： B03C1/01 , B03C1/00
CPC分类号： B01F13/0059 , B01F3/0815 , B01F13/0006 , B01F13/0809 , B03C1/01 , B03C1/288 , B03C1/30 , B03C2201/32 , Y10T436/25375
摘要： Methods for in-line purification of surfactant from a first fluid, such as a microemulsion are disclosed. Magnetic particles coated with surfactant molecules may be used to bind surfactants from a fluid. A magnetic field may be used to separate the bound materials from the fluid.

7. 发明申请

US20120006681A1 Controlled Dispensing of Ultrafine, Variable Volume, Emulsion Droplets 审中-公开
标题翻译：超细，可变体积，乳液滴的控制分配
公开(公告)号：US20120006681A1
公开(公告)日：2012-01-12
申请号：US13177453
申请日：2011-07-06
申请人： Karan V.I.S. Kaler , Ravi Prakash , Dipankar Chugh
发明人： Karan V.I.S. Kaler , Ravi Prakash , Dipankar Chugh
IPC分类号： C25B15/00 , C25B9/00
CPC分类号： B01F3/0815 , B01F13/0076 , B01F2215/0431 , B01L3/0268 , B01L3/502707 , B01L3/50273 , B01L3/502792 , B01L2200/0647 , B01L2200/0694 , B01L2300/089 , B01L2300/161 , B01L2400/0424 , B01L2400/0427 , B01L2400/086
摘要： Embodiments of the present invention comprise a surface microfluidic system with varying coplanar electrode structure capable of precision dispensing of an array of variable volume droplets in a rapid, controlled and automated fashion. Furthermore, the invention provides surface microfluidic methods and systems for the creation and transport of emulsion droplets, including vesicles and cells.
摘要翻译：本发明的实施例包括具有变化的共面电极结构的表面微流体系统，其能够以快速，受控和自动的方式精确地分配可变体积的液滴阵列。此外，本发明提供了用于产生和输送乳液液滴的表面微流体方法和系统，包括囊泡和细胞。

8. 发明授权

US5762775A Method for electrically producing dispersions of a nonconductive fluid in a conductive medium 失效
标题翻译：在导电介质中电解产生非导电流体的分散体的方法
公开(公告)号：US5762775A
公开(公告)日：1998-06-09
申请号：US751180
申请日：1996-11-15
申请人： David W. DePaoli , Constantinos Tsouris , James Q. Feng
发明人： David W. DePaoli , Constantinos Tsouris , James Q. Feng
IPC分类号： B01F3/08
CPC分类号： B01F3/04978 , B01F13/0003 , B01F3/0815
摘要： A method for use in electrically forming dispersions of a nonconducting fluid in a conductive medium that minimizes power consumption, gas generation, and sparking between the electrode of the nozzle and the conductive medium. The method utilizes a nozzle having a passageway, the wall of which serves as the nozzle electrode, for the transport of the nonconducting fluid into the conductive medium. A second passageway provides for the transport of a flowing low conductivity buffer fluid which results in a region of the low conductivity buffer fluid immediately adjacent the outlet from the first passageway to create the necessary protection from high current drain and sparking. An electrical potential difference applied between the nozzle electrode and an electrode in contact with the conductive medium causes formation of small droplets or bubbles of the nonconducting fluid within the conductive medium. A preferred embodiment has the first and second passageways arranged in a concentric configuration, with the outlet tip of the first passageway withdrawn into the second passageway.
摘要翻译：一种用于在导电介质中电化形成不导电流体的分散体的方法，其最小化喷嘴的电极和导电介质之间的功率消耗，气体产生和火花。该方法利用具有通道的喷嘴，该通道的壁用作喷嘴电极，用于将非导体流体输送到导电介质中。第二通道提供流动的低电导率缓冲流体的输送，其导致低电导率缓冲流体的区域紧邻第一通道的出口，以产生必须的保护，防止高电流消耗和火花。在喷嘴电极和与导电介质接触的电极之间施加的电位差导致在导电介质内形成非导电流体的小液滴或气泡。优选实施例具有以同心配置布置的第一和第二通道，第一通道的出口端部被拉入第二通道。

9. 发明授权

US4722787A Apparatus for contacting two immiscible liquids with the application of an electric field 失效
标题翻译：用于接触两种不混溶液体与施加电场的装置
公开(公告)号：US4722787A
公开(公告)日：1988-02-02
申请号：US761358
申请日：1985-08-01
申请人： Christine Fombarlet , Michel Guenehec , Francis Lancelot , Laurent Martin , Paul Vignet
发明人： Christine Fombarlet , Michel Guenehec , Francis Lancelot , Laurent Martin , Paul Vignet
IPC分类号： B01D11/04 , B01D17/06 , B01F3/08 , B01F13/00
CPC分类号： B01D11/0419 , B01D17/06 , B01F3/0815
摘要： The invention relates to an apparatus for contacting two immiscible liquids having at least one electrode for the application of an electric field.The electrode is coated with at least two layers of different insulating materials, the first layer which is in contact with the electrode being formed from a liquid insulating material, e.g. benzylneocaprate or transformer oil, while the outer layer is formed from a solid insulating material, e.g. polytetrafluoroethylene.These electrodes are preferably in the form of bars arranged parallel to the fluid flow direction and they are provided with deflectors to ensure that no dispersed phase flow in the form of a film takes place along the bars.
摘要翻译：本发明涉及一种用于接触具有至少一个用于施加电场的电极的两种不混溶液体的装置。电极涂覆有至少两层不同的绝缘材料，与电极接触的第一层由液体绝缘材料形成，例如，苄基碳酸酯或变压器油，而外层由固体绝缘材料形成，例如，聚四氟乙烯。这些电极优选地是平行于流体流动方向布置的条形，并且它们设置有偏转器，以确保不沿着条形成膜的分散相流。

10. 发明申请

US20180296992A1 SYSTEM AND METHOD FOR DROPLET FORMATION AND MANIPULATION USING FERROFLUIDS 审中-公开
公开(公告)号：US20180296992A1
公开(公告)日：2018-10-18
申请号：US15767979
申请日：2016-10-07
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： Dino Di Carlo , Soroush Kahkeshani
IPC分类号： B01F3/08 , B01F13/00 , A61K9/00
CPC分类号： B01F3/0815 , A61K9/0009 , A61K9/0021 , A61K9/0024 , A61K9/0097 , A61M2037/0023 , B01F13/0059 , B01F13/0077 , B01L3/502761 , B01L3/502784 , B01L2200/0668 , B01L2300/0816 , B01L2300/0867 , B01L2400/043 , G01N35/1002 , G01N2035/1034
摘要： A microfluidic device for forming droplets includes at least one ferrofluid reservoir disposed in the microfluidic device and containing a ferrofluid therein. The microfluidic device includes a continuous-phase reservoir disposed in the microfluidic device and containing an oil phase therein and one or more microfluidic channels connecting between the at least one ferrofluid reservoir and the continuous-phase reservoir, the continuous-phase reservoir comprising a step region having an increased height as compared to a height of the one or more microfluidic channels. To form droplets an externally applied magnetic field is applied to the device to pull the ferrofluid into the continuous-phase reservoir, whereby droplets are formed at step region.

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