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    • 3. 发明申请
    • Injection Arrangement for a Flowable Drug
    • 可流动药物的注射装置
    • US20120209249A1
    • 2012-08-16
    • US13377155
    • 2010-06-18
    • Nils BassoThomas NagelRene RichterRobert Witt
    • Nils BassoThomas NagelRene RichterRobert Witt
    • A61M5/30A61M5/20
    • A61M5/282A61M5/1486A61M5/30A61M2005/14513
    • The invention refers to an injection arrangement (1) comprising a replaceable container cartridge (2) for a flowable drug (5), the container cartridge (2) comprising a deformable bag (4) arranged inside and sealed against a rigid outer casing (3), the deformable bag (4) being arranged for holding the flowable drug (5) and in fluid communication with an outlet (6), the rigid outer casing (3) fillable by a displacement fluid (7) for displacing the deformable bag (4), the injection arrangement (1) further comprising a reservoir (8) for the displacement fluid (7) and a pump (9) for pumping the displacement fluid (7) from the reservoir (8) into the rigid outer casing (3) and/or from the rigid outer casing (3) into the reservoir (8) via a fluid channel (10).
    • 本发明涉及一种包括用于可流动药物(5)的可更换容器盒(2)的注射装置(1),所述容器盒(2)包括布置在内部并密封在刚性外壳(3)上的可变形袋(4) ),所述可变形袋(4)被布置用于保持所述可流动药物(5)并与出口(6)流体连通,所述刚性外壳(3)可由位移流体(7)填充以使所述可变形袋 如图4所示,喷射装置(1)还包括用于排出流体(7)的储存器(8)和用于将储存器(8)的排出流体(7)泵送到刚性外壳体(3)中的泵(9) )和/或从刚性外壳(3)经由流体通道(10)进入储存器(8)。
    • 6. 发明申请
    • CONTROLLABLE DRUG DELIVERY DEVICE
    • 可控制药物递送装置
    • US20100087778A1
    • 2010-04-08
    • US12604278
    • 2009-10-22
    • Amir GenosarJonathan GoldsteinNiles A. FleisherYehuda BacharYossi Aldar
    • Amir GenosarJonathan GoldsteinNiles A. FleisherYehuda BacharYossi Aldar
    • A61M5/168
    • A61M5/14248A61M5/14593A61M5/1486A61M2005/14252A61M2005/14268A61M2005/14506A61M2205/0272
    • A controllable drug delivery device for delivering a liquid injectable drug, said device comprising a drug reservoir (22), a drug administration device (28), a displacement-generating battery (20), and a current-depletion circuit (85), wherein displacement generated by said battery as current is depleted from the battery by the current depletion circuit displaces a wall of the drug reservoir thereby causing the reservoir to expel liquid injectable drug contained therein via said drug administration device, and wherein the drug delivery device further includes a controller (78) that is responsive to a measured parameter indicative of displacement generated by the battery for applying a variable load (80) across the battery in order to provide a substantially constant-current depletion of said battery and thereby cause said drug delivery device to deliver a substantially constant drug delivery rate.
    • 一种用于输送液体可注射药物的可控药物递送装置,所述装置包括药物储存器(22),药物施用装置(28),排量产生电池(20)和耗尽电路(85),其中 所述电池产生的位移由电流耗尽电路从电池中耗尽,使药剂贮存器的壁移位,从而使储存器经由所述药物给药装置排出其中所含的液体可注射药物,并且其中所述药物输送装置还包括 控制器(78),其响应于指示由所述电池产生的位移的测量参数,以在所述电池上施加可变负载(80),以便提供所述电池的基本上恒定的电流消耗,从而使所述药物递送装置 提供基本上恒定的药物递送率。
    • 7. 发明申请
    • Body-insertable apparatus
    • 身体可插入装置
    • US20090043278A1
    • 2009-02-12
    • US11658509
    • 2006-05-25
    • Shinsuke TanakaHironao KawanoHironobu Takizawa
    • Shinsuke TanakaHironao KawanoHironobu Takizawa
    • A61M5/20
    • A61M31/002A61M5/14248A61M5/14276A61M5/1452A61M5/1454A61M5/1486A61M5/172A61M5/3287A61M2005/14252A61M2005/14284
    • A body-insertable apparatus that can reduce the apparatus size and perform projection operation of an injection needle in a power saving manner is provided. A body-insertable apparatus 1 according to the present invention has a balloon 4 for storing a medical fluid in a capsule-like casing 2, and an injection needle 5 including an elastic membrane 6. The body-insertable apparatus 1 discharges the medical fluid due to contraction of the balloon 4, applies a discharge pressure of the medical fluid to the elastic membrane 6 to expand the elastic membrane 6, and projects the injection needle 5 from the casing 2 due to the expansion of the elastic membrane 6. Further, the body-insertable apparatus 1 has a channel forming unit 11 for forming a channel 11a connecting to the balloon 4 and a channel 11b connecting to the injection needle 5, and a communication adjusting mechanism 12. The communication adjusting mechanism 12 adjusts a communicated state between the channels 11a and 11b, thereby controlling the start of medical-fluid discharge operation by the balloon 4.
    • 提供一种能够以省电的方式减小设备尺寸并执行注射针的投影操作的被检体内导入装置。 根据本发明的被检体内导入装置1具有用于将药液流体存储在胶囊型外壳2中的气囊4和具有弹性膜6的注射针5.被检体内导入装置1将药液排出, 使气囊4收缩,向弹性膜6施加药液的排出压力,使弹性膜6膨胀,并由于弹性膜6的膨胀而将注射针5从壳体2突出。此外, 身体可插入装置1具有用于形成连接到球囊4的通道11a和连接到注射针5的通道11b的通道形成单元11和连通调节机构12.连通调节机构12调节 通道11a和11b,从而控制气囊4开始进行医药流体排出操作。
    • 8. 发明申请
    • Medical skin mountable device
    • 医用皮肤安装装置
    • US20060264835A1
    • 2006-11-23
    • US11411081
    • 2006-04-25
    • Ole NielsenJim RadmerJan Preuthun
    • Ole NielsenJim RadmerJan Preuthun
    • A61M5/32
    • A61M5/14248A61M5/14216A61M5/14224A61M5/14526A61M5/1486A61M2005/14252A61M2005/14268A61M2005/14506A61M2005/14513A61M2005/1585
    • A medical device is provided comprising a transcutaneous device unit and a reservoir unit. The transcutaneous device unit comprises a transcutaneous device for transporting a fluid through a skin portion of a subject, and a mounting surface adapted for application to the skin of the subject. The reservoir unit comprises a reservoir adapted to contain a fluid drug, the reservoir comprising an outlet means allowing the transcutaneous device to be arranged in fluid communication with an interior of the reservoir, and an expelling assembly for expelling a fluid drug out of the reservoir and through the skin of the subject via the transcutaneous device. The transcutaneous device unit and the reservoir unit further comprise coupling means allowing the reservoir unit to be secured to the transcutaneous device unit in the situation of use. By this arrangement a two-unit system is provided which can be used in a convenient and cost-effective manner.
    • 提供了包括经皮装置单元和储存器单元的医疗装置。 经皮装置单元包括用于输送流体通过受试者的皮肤部分的经皮装置和适于施用于受试者皮肤的安装表面。 储存器单元包括适于容纳流体药物的储存器,储存器包括允许经皮装置与储存器的内部流体连通的出口装置和用于将流体药物排出储存器的排出组件,以及 通过经皮装置穿过受试者的皮肤。 经皮装置单元和储存器单元还包括联接装置,允许储存器单元在使用情况下固定到经皮装置单元。 通过这种布置,提供了可以以便利且具有成本效益的方式使用的两单元系统。
    • 9. 发明申请
    • DISPOSABLE FLUID CONTAINER WITH INTEGRATED PUMP MOTIVE ASSEMBLY
    • 具有集成泵动力组件的可替换的流体容器
    • US20060264829A1
    • 2006-11-23
    • US11382502
    • 2006-05-10
    • William DONALDSON
    • William DONALDSON
    • A61M37/00A61B19/00A61K9/22
    • A61M5/14212A61J1/14A61M5/142A61M5/14224A61M5/1486A61M5/16809A61M2205/0283A61M2205/0294B67D7/0216
    • A disposable fluid container (20) comprises an integrated pump motive assembly (50) for pumping fluid from an interior of the container. In some example embodiments, the integrated pump motive assembly (50) is situated at least partially within the container housing, e.g., at least partially or even completely submerged inside a fluid reservoir (30) defined by the container housing (22). In other example embodiments, the pump motive assembly is outside the fluid reservoir (30), yet still integrally formed with the container. In yet other embodiments, the pump motive assembly is in a lid (194) of the container. As one aspect of this disposable pump-integrated container technology, the pump motive assembly comprises a displaceable electrodynamic actuator, such as (for example) piezoelectric diaphragm pump, taking any of various configurations. As another and distinct aspect of this disposable pump-integrated container technology, the pump motive assembly is connected via an electrical lead (78) and/or terminal (80) to receive pump driving signals from outside the container.
    • 一次性流体容器(20)包括用于从容器的内部泵送流体的集成泵运动组件(50)。 在一些示例性实施例中,集成泵运动组件(50)至少部分地位于容器壳体内,例如至少部分或甚至完全浸没在由容器壳体(22)限定的流体储存器(30)内。 在其他示例性实施例中,泵动力组件在流体容器(30)的外部,但仍与容器一体形成。 在其他实施例中,泵动力组件位于容器的盖(194)中。 作为这种一次性泵一体式集装箱技术的一个方面,泵动力组件包括可移动的电动致动器,例如(例如)压电隔膜泵,采用各种配置中的任何一种。 作为该一次性泵一体式集装箱技术的另一个明显的方面,泵动机组件经由电引线(78)和/或端子(80)连接以从容器的外部接收泵驱动信号。
    • 10. 发明申请
    • FLUID CONTAINER WITH INTEGRATED VALVE
    • 带集成阀的流体容器
    • US20060255064A1
    • 2006-11-16
    • US11382504
    • 2006-05-10
    • William DONALDSON
    • William DONALDSON
    • B65D35/28
    • A61M5/14212A61J1/14A61M5/142A61M5/14224A61M5/1486A61M5/16809A61M2205/0283A61M2205/0294B67D7/0216
    • Embodiments of fluid storage containers (312) comprise a displaceable electrodynamic valve (344) for selectively regulating release of fluid from the container. The fluid storage container has a port (342) and comprises means for defining a reservoir (330) for accommodating a pressurizing a fluid. A displaceable electrodynamic valve selectively opens and closes the port and thereby regulates release of the pressurized fluid from the container. In some implementations, the container has a lid (400) and the port is provided in the container lid. In other implementations, the container has a container body, and the port is provided in the container body. The displaceable electrodynamic valve (344) can take various configurations (e.g., flapper, solenoid) and various forms (e.g., piezoelectric valve) in differing example embodiments. In some embodiments a compressor (361) is provided for pressurizing the fluid, and can also take various forms.
    • 流体储存容器(312)的实施例包括用于选择性地调节流体从容器释放的可移动电动力阀(344)。 流体存储容器具有端口(342)并且包括用于限定用于容纳加压流体的储存器(330)的装置。 选择性地打开和关闭端口,从而调节加压流体从容器释放的位移电动阀。 在一些实施方案中,容器具有盖(400),并且该端口设置在容器盖中。 在其他实施方案中,容器具有容器主体,并且该端口设置在容器主体中。 在不同的示例性实施例中,可移位电动阀(344)可以采取各种构造(例如,挡板,螺线管)和各种形式(例如,压电阀)。 在一些实施例中,提供压缩机(361)以对流体加压,并且还可以采取各种形式。