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1. 发明授权

US11759546B2 Implantable objects, guiding devices, and methods of use thereof 有权
公开(公告)号：US11759546B2
公开(公告)日：2023-09-19
申请号：US15778520
申请日：2016-11-23
申请人： RevBio, Inc.
发明人： George W. Kay , Brian J. Hess
IPC分类号： A61C8/00 , A61L24/04 , A61C1/08 , A61B17/17 , A61C8/02 , A61B17/32 , A61B17/58 , A61C13/225 , A61B90/00 , A61B17/84 , A61B17/86 , A61C1/07 , A61F2/44 , A61F2/46 , A61B17/56 , A61B17/70 , A61F2/30 , F16B11/00
CPC分类号： A61L24/04 , A61B17/17 , A61B17/32 , A61B17/58 , A61B17/84 , A61B17/86 , A61B90/39 , A61C1/07 , A61C1/084 , A61C8/00 , A61C8/0006 , A61C8/0009 , A61C8/0036 , A61C8/0048 , A61C8/0068 , A61C13/225 , A61F2/447 , A61F2/4611 , A61B17/7062 , A61B2017/564 , A61B2090/3983 , A61C8/005 , A61C2008/0046 , A61F2002/30433 , A61F2002/30448 , A61F2002/4687 , F16B11/00
摘要： Embodiments of the disclosure relate to implantable objects and guiding devices, as well as recipient site preparation instruments, bone-implantable materials, and methods of fabrication and use thereof.

2. 发明授权

US09408943B2 Method and device for female urinary incontinence 有权
标题翻译：女性尿失禁的方法和装置
公开(公告)号：US09408943B2
公开(公告)日：2016-08-09
申请号：US14207259
申请日：2014-03-12
申请人： ParaPatch, Inc.
发明人： Cora St. Anne
IPC分类号： A61L24/04 , A61F2/00 , A61F13/472 , A61F13/15
CPC分类号： A61L24/04 , A61F2/0009 , A61F13/47209 , A61F2013/15097 , A61L24/001
摘要： A method and device for use in stress female urinary incontinence. A small, flexible adhesive patch is applied directly to the clitoris of a person suffering from stress female urinary incontinence. The adhesive is of a type sufficient to stimulate the mechanoreceptors located in the clitoris whereby to inhibit discharge from the bladder. The patch is formed of a backing sheet of an impervious material containing adhesive on one side. A release liner prevents the adhesive from drying out.
摘要翻译：一种用于压力性女性尿失禁的方法和装置。一个小的，柔性的粘合贴片直接应用于压力性女性尿失禁患者的阴蒂。粘合剂具有足以刺激位于阴蒂中的机械感受体的类型，从而抑制从膀胱排出。该贴片由一面上含有粘合剂的不透水材料的背板形成。剥离衬垫防止粘合剂变干。

3. 发明授权

US08980425B2 Bioactive material 有权
标题翻译：生物活性物质
公开(公告)号：US08980425B2
公开(公告)日：2015-03-17
申请号：US12674236
申请日：2008-08-19
申请人： Graeme Howling , Paul Gunning
发明人： Graeme Howling , Paul Gunning
IPC分类号： B32B15/04 , B32B5/00 , B32B5/16 , B05D3/12 , B82Y99/00 , A61L24/04 , A61L27/30 , C23C22/64
CPC分类号： A61F2/28 , A61L24/04 , A61L27/04 , A61L27/306 , C23C22/64 , Y10S977/755 , Y10T428/24942 , Y10T428/256 , Y10T428/265 , Y10T428/31678
摘要： The present invention relates to a bioactive material and to a method of producing a bioactive material which is suitable for use as an implant or for use as a bone substitute for repairing bone.
摘要翻译：本发明涉及生物活性材料和生产活性材料的方法，该生物活性材料适合用作植入物或用作修复骨的骨替代物。

4. 发明申请

US20140277112A1 INJECTABLE HYDROGELS 有权
标题翻译：可注射水压
公开(公告)号：US20140277112A1
公开(公告)日：2014-09-18
申请号：US13800013
申请日：2013-03-13
申请人： ST. JUDE MEDICAL SYSTEMS AB
发明人： Lisa MELLIN , Niklas BORG , Martina KÄLLROT
IPC分类号： A61L24/00 , A61L24/04 , A61K47/34
CPC分类号： A61L24/0031 , A61K47/34 , A61L24/04 , A61L24/046 , A61L27/14 , A61L27/52 , A61L2430/36 , C08L101/02
摘要： Described herein are methods of forming hydrogels comprising combining (a) a water-soluble polymer comprising thiol groups, and (b) a water-soluble metal salt in an aqueous solution. The hydrogels form rapidly. Hydrogels and related methods, uses, and products also are described.
摘要翻译：本文描述了形成水凝胶的方法，其包括将（a）包含硫醇基的水溶性聚合物和（b）水溶液中的水溶性金属盐组合。水凝胶形成迅速。还描述了水凝胶及相关方法，用途和产品。

5. 发明授权

US08790488B2 Biocompatible surgical compositions 有权
标题翻译：生物相容性手术组合物
公开(公告)号：US08790488B2
公开(公告)日：2014-07-29
申请号：US13732699
申请日：2013-01-02
申请人： Covidien LP
发明人： Ahmad R. Hadba , Nadya Belcheva
IPC分类号： C09J4/00 , C08G18/32 , C08G18/42 , C09J177/00 , A61L24/04 , A61B17/00 , C08G18/48 , C08G18/46 , C09J175/04 , C08G18/28 , C08G18/10
CPC分类号： C09J177/00 , A61B17/0057 , A61L24/04 , C08G18/10 , C08G18/283 , C08G18/3203 , C08G18/3206 , C08G18/3278 , C08G18/3281 , C08G18/4277 , C08G18/4615 , C08G18/4887 , C08G18/73 , C08G2190/00 , C08G2230/00 , C08L77/04 , C09J175/04
摘要： Biocompatible macromer compositions are provided including an isocyanate-functional polyalkylene oxide combined with at least one multi-functional isocyanate as a first component, and a multi-amino functional compound possessing multiple primary amines as a second component. The isocyanate-functional polyalkylene oxide has pendant polyalkylene oxide groups. The resulting biocompatible macromer composition can be employed as an adhesive or sealant for medical/surgical uses.
摘要翻译：提供生物相容性大分子单体组合物，其包括与作为第一组分的至少一种多官能异氰酸酯组合的异氰酸酯官能的聚环氧烷烃，以及具有多个伯胺作为第二组分的多氨基官能化合物。异氰酸酯官能的聚环氧烷具有侧链聚环氧烷基团。所得的生物相容性大分子单体组合物可用作医疗/外科用途的粘合剂或密封剂。

6. 发明授权

US08684008B2 Method and device for female urinary incontinence 有权
标题翻译：女性尿失禁的方法和装置
公开(公告)号：US08684008B2
公开(公告)日：2014-04-01
申请号：US12999114
申请日：2010-05-03
申请人： Cora St. Anne
发明人： Cora St. Anne
IPC分类号： A61F5/48 , A61F13/20
CPC分类号： A61L24/04 , A61F2/0009 , A61F13/47209 , A61F2013/15097 , A61L24/001
摘要： A method and device for use in stress female urinary incontinence. A small, flexible adhesive patch is applied to the clitoris of a person suffering from stress female urinary incontinence. The adhesive is of a type sufficient to stimulate the mechanoreceptors located in the clitoris whereby to inhibit discharge from the bladder. The patch is formed of a backing sheet of an impervious film material containing adhesive on one side. A release liner prevents the adhesive from drying out.
摘要翻译：一种用于压力性女性尿失禁的方法和装置。一个小的，柔性的粘合贴片被应用于患有压力性女性尿失禁的人的阴蒂。粘合剂具有足以刺激位于阴蒂中的机械感受体的类型，从而抑制从膀胱排出。该贴片是由一面包含粘合剂的不透水薄膜材料的背衬片形成的。剥离衬垫防止粘合剂变干。

7. 发明申请

US20130098550A1 FUNCTIONALIZED ADHESIVE FOR MEDICAL DEVICES 有权
标题翻译：功能性胶粘剂用于医疗器械
公开(公告)号：US20130098550A1
公开(公告)日：2013-04-25
申请号：US13637172
申请日：2011-03-24
申请人： Tim Sargeant , Robert Ahmad Hadba , Joshua Stopek
发明人： Tim Sargeant , Robert Ahmad Hadba , Joshua Stopek
IPC分类号： A61L24/00
CPC分类号： A61L24/001 , A61L15/58 , A61L24/04 , A61L27/14 , A61L27/50 , A61L31/14
摘要： A method for adhering a medical device to biological tissue includes adhering an adhesive composition having a plurality of reactive members of a specific binding pair to tissue which has a plurality of complementary reactive members of the specific binding pair via click chemistry.
摘要翻译：用于将医疗装置粘附到生物组织的方法包括通过点击化学将具有多个特异性结合对的反应性成员的粘合剂组合物粘附到具有多个特异性结合对的互补反应性成员的组织。

8. 发明申请

US20100240798A1 REDOX-CURING TYPE NONAQUEOUS CURABLE COMPOSITION 审中-公开
标题翻译：氧化固化型非水溶性组合物
公开(公告)号：US20100240798A1
公开(公告)日：2010-09-23
申请号：US12789997
申请日：2010-05-28
申请人： Mitsunobu KAWASHIMA , Aki Takase
发明人： Mitsunobu KAWASHIMA , Aki Takase
IPC分类号： A61K6/00
CPC分类号： C08F4/40 , A61K6/0023 , A61L24/04
摘要： The present invention relates to processes of making a cured dental adhesive compositions, in contact with a wetting material surface, by contacting the wetting material surface having water present on the surface with a nonaqueous composition including at least one liquid radical polymeric monomer (a), an organic peroxide (b), and a water-soluble reducing compound (c) in the form of a solid, where the water-soluble reducing compound (c) is dispersed in the liquid radical polymeric monomer (a); and solvating the water-soluble reducing compound (c) present at an interface between the redox-curing nonaqueous curable composition and the wetting material with the water present on the wetting material surface.
摘要翻译：本发明涉及通过使具有表面上存在的水的润湿材料表面与包含至少一种液体自由基聚合单体（a）的非水性组合物接触来制备与润湿材料表面接触的固化牙科粘合剂组合物的方法，有机过氧化物（b）和水溶性还原化合物（c），其中水溶性还原化合物（c）分散在液体自由基聚合单体（a）中; 并且使用存在于润湿材料表面上的水溶解存在于氧化还原固化非水可固化组合物和润湿材料之间的界面处的水溶性还原化合物（c）。

9. 发明授权

US07722934B2 Biological repair material compatible with biological tissue adhesive 有权
标题翻译：生物修复材料与生物组织粘合剂相容
公开(公告)号：US07722934B2
公开(公告)日：2010-05-25
申请号：US10525724
申请日：2003-08-29
申请人： Yoshiaki Suzuki , Hiroshi Ujiie , Noriyoshi Takahashi , Masaya Iwaki
发明人： Yoshiaki Suzuki , Hiroshi Ujiie , Noriyoshi Takahashi , Masaya Iwaki
IPC分类号： B05D3/06
CPC分类号： A61L27/16 , A61L17/12 , A61L17/14 , A61L24/001 , A61L24/04 , A61L27/14 , A61L27/18 , A61L27/50 , A61L27/507 , A61L2400/18 , Y10T428/3154 , C08L27/18 , C08L67/04
摘要： An object of the present invention is to provide a means for improving the affinity of an in vivo embedded material such as an artificial blood vessel or an artificial dura mater with a tissue adhesive, so as to quickly prevent the leakage of the blood or spinal fluid. The present invention provides a polymeric material used in combination with a tissue adhesive, which comprises carbon or silicon as a constitutional element, and at least a portion of the surface of which is modified by ion bombardment.
摘要翻译：本发明的目的是提供一种用于提高体内嵌入材料如人造血管或人造硬膜与组织粘合剂的亲和力的方法，以便快速防止血液或脊髓液泄漏。本发明提供了与组织粘合剂组合使用的聚合物材料，其包含碳或硅作为构成元素，其表面的至少一部分通过离子轰击而被改性。

10. 发明申请

US20090264555A1 Cyanoacrylate tissue adhesive formulations with multipurpose rheology modifiers 有权
标题翻译：具有多用途流变改性剂的氰基丙烯酸酯组织粘合剂配方
公开(公告)号：US20090264555A1
公开(公告)日：2009-10-22
申请号：US12386401
申请日：2009-04-18
申请人： Shalaby W. Shalaby , Michael Aaron Vaughn , James M. Lindsey, III
发明人： Shalaby W. Shalaby , Michael Aaron Vaughn , James M. Lindsey, III
IPC分类号： A61L24/04
CPC分类号： A61L24/06 , A61L24/04 , A61K6/0017 , C08L33/14 , A61K6/0023
摘要： Absorbable and non-absorbable cyanoacrylate tissue adhesive/sealant formulations include at least one multipurpose carboxylic, acid-bearing C-succinylated polymeric rheology modifier capable of increasing the viscosity of the liquid formulation, while controlling the anionic polymerization of the cyanoacrylate monomers and increasing the compliance of the cured solid adhesive.
摘要翻译：可吸收和不可吸收的氰基丙烯酸酯组合粘合剂/密封剂制剂包括至少一种多功能羧酸，含酸的C琥珀酰化聚合物流变改性剂，其能够增加液体制剂的粘度，同时控制氰基丙烯酸酯单体的阴离子聚合并增加顺应性的固化固体粘合剂。

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