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1. 发明授权

US09801538B2 Systems and methods for processing portable wavefront aberrometer data 有权
公开(公告)号：US09801538B2
公开(公告)日：2017-10-31
申请号：US14628325
申请日：2015-02-23
申请人： Smart Vision Labs
发明人： Yaopeng Zhou
IPC分类号： A61B3/10 , A61B3/00 , A61B3/18 , A61B3/14
CPC分类号： A61B3/1015 , A61B3/0008 , A61B3/10 , A61B3/14 , A61B3/185 , G06F19/00
摘要： Systems and methods for processing portable wavefront aberrometer data are disclosed. In one embodiment, a method includes receiving, from a mobile computing device, image data captured by a light detector of the mobile computing device, the image data corresponding to light reflected from an eye of a patient and passed through a portable wavefront aberrometer coupled to the mobile computing device. The method further includes processing the image data to compute a patient-specific parameter associated with the patient, and transmitting the patient-specific parameter to one or more of the mobile computing device or a computing device associated with a medical provider.

2. 发明申请

US20170258320A1 DEVICE FOR GENERATING A DETECTABLE SIGNAL BASED UPON CONCENTRATION OF AT LEAST ONE SUBSTANCE 审中-公开
公开(公告)号：US20170258320A1
公开(公告)日：2017-09-14
申请号：US15602523
申请日：2017-05-23
申请人： GEELUX HOLDINGS, LTD.
发明人： Marcio Marc ABREU
IPC分类号： A61B3/10 , A61B3/00 , A61B3/12 , A61B3/16 , A61B3/18 , A61B5/00 , A61B5/145 , A61B5/1455 , A61F9/00 , G02C7/04 , A61B5/01 , A61B5/03 , A61B5/1486 , A61B5/18 , A61B8/00 , A61B8/06
CPC分类号： A61B3/10 , A61B3/0025 , A61B3/0058 , A61B3/1241 , A61B3/16 , A61B3/185 , A61B5/0002 , A61B5/01 , A61B5/031 , A61B5/14507 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1455 , A61B5/14555 , A61B5/1486 , A61B5/18 , A61B5/412 , A61B5/416 , A61B5/445 , A61B5/4839 , A61B5/6814 , A61B8/06 , A61B8/56 , A61B2560/0214 , A61B2560/0219 , A61B2560/0252 , A61B2560/0418 , A61B2562/0238 , A61B2562/12 , A61F9/0017 , A61F9/0026 , G02C7/04 , Y02A90/26
摘要： Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and/or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.

3. 发明授权

US08419185B2 Methods and devices for refractive correction of eyes 有权
$Methods and devices for refractive correction of eyes$
标题翻译：眼睛屈光矫正的方法和装置
公开(公告)号：US08419185B2
公开(公告)日：2013-04-16
申请号：US13116262
申请日：2011-05-26
申请人： Junzhong Liang
发明人： Junzhong Liang
IPC分类号： A61B3/10
CPC分类号： A61B3/103 , A61B3/0025 , A61B3/0285 , A61B3/1015 , A61B3/185 , G01M11/0228 , G02C7/02 , G02C7/022 , G02C7/027 , G02C2202/22
摘要： Methods and devices are provided to obtain refractive correction with superior visual acuity (e.g., 20/10) by achieving an astigmatism-free customized refractive correction. The astigmatism-free customized refractive correction involves obtaining an objective and precise measurement of cylindrical power in a resolution between 0.01 D and 0.10 D in an eye using an objective aberrometer, reliably relating the cylindrical axis obtained from the objective aberrometer to that in a phoroptor, determining an optimized focus error of an eye through subjective refraction with a phoroptor, generating a customized refraction by combining the objective measured cylindrical power, the objective measured cylindrical axis, and the subjectively measured focus power, fabricating a custom lens with a tolerance finer than 0.09 D based on the generated customized refraction, and delivering an ophthalmic lens that can provide an astigmatism-free refractive correction for an eye.
摘要翻译：提供了通过实现无像散的定制屈光矫正来获得具有优异视力（例如，20/10）的屈光矫正的方法和装置。无像差的定制屈光矫正涉及使用目标像差仪在眼睛内以0.01D和0.10D之间的分辨率获得圆柱光焦度的客观和精确的测量，可靠地将从目标像差仪获得的圆柱轴与陀螺仪中的圆柱轴相关联，通过主观折射来确定眼睛的优化聚焦误差，通过组合目标测量柱面光焦度，物镜测量柱面轴和主观测量焦点焦距产生定制折射，制造具有比0.09宽的公差的定制镜片 D，基于生成的定制折射，以及递送可以为眼睛提供无像散的屈光矫正的眼科镜片。

4. 发明申请

US20110040161A1 Device for generating a detectable signal based upon concentration of at least one substance 失效
标题翻译：用于基于至少一种物质的浓度产生可检测信号的装置
公开(公告)号：US20110040161A1
公开(公告)日：2011-02-17
申请号：US12805036
申请日：2010-07-08
申请人： Marcio Marc Abreu
发明人： Marcio Marc Abreu
IPC分类号： A61B6/00 , A61N5/06 , A61M36/12 , A61N5/10
CPC分类号： A61B3/10 , A61B3/0025 , A61B3/0058 , A61B3/1241 , A61B3/16 , A61B3/185 , A61B5/0002 , A61B5/01 , A61B5/031 , A61B5/14507 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1455 , A61B5/14555 , A61B5/1486 , A61B5/18 , A61B5/412 , A61B5/416 , A61B5/445 , A61B5/4839 , A61B5/6814 , A61B8/06 , A61B8/56 , A61B2560/0214 , A61B2560/0219 , A61B2560/0252 , A61B2560/0418 , A61B2562/0238 , A61B2562/12 , A61F9/0017 , A61F9/0026 , G02C7/04 , G06F19/00 , Y02A90/26
摘要： Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and/or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.
摘要翻译：利用放置在眼睛上的接触装置，以便根据这些物理和化学参数检测身体的物理和化学参数以及化合物的非侵入性递送，其中信号作为电磁波，无线电波，红外线等。要检测的参数之一包括使用在结膜和泪液膜中发现的化学变化和化学产物的非侵入性血液分析。安装在敷设在角膜或眼睛表面上的接触装置中的传感器能够评估和测量眼睛中的物理和化学参数，包括非侵入性血液分析。该系统利用眼罩运动和/或关闭眼罩来启动安装在接触装置中的微型射频敏感传感器。该信号可以通过电线或遥控的无线电通信到外部放置的接收器。然后可以处理，分析和存储信号。可以检测到几个参数，包括血液成分的全面无创分析，全身和眼部血流量的测量，心率和呼吸频率的测量，跟踪操作，排卵检测，辐射检测和药物作用，眼睛和全身性疾病等。

5. 发明授权

US07756559B2 Device for generating a detectable signal based upon antibody/antigen interaction 失效
标题翻译：用于基于抗体/抗原相互作用产生可检测信号的装置
公开(公告)号：US07756559B2
公开(公告)日：2010-07-13
申请号：US10448427
申请日：2003-05-30
申请人： Marcio Marc Abreu
发明人： Marcio Marc Abreu
IPC分类号： A61B5/00
CPC分类号： A61B3/10 , A61B3/0025 , A61B3/0058 , A61B3/1241 , A61B3/16 , A61B3/185 , A61B5/0002 , A61B5/01 , A61B5/031 , A61B5/14507 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1455 , A61B5/14555 , A61B5/1486 , A61B5/18 , A61B5/412 , A61B5/416 , A61B5/445 , A61B5/4839 , A61B5/6814 , A61B8/06 , A61B8/56 , A61B2560/0214 , A61B2560/0219 , A61B2560/0252 , A61B2560/0418 , A61B2562/0238 , A61B2562/12 , A61F9/0017 , A61F9/0026 , G02C7/04 , G06F19/00 , Y02A90/26
摘要： Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and/or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.
摘要翻译：利用放置在眼睛上的接触装置，以便根据这些物理和化学参数检测身体的物理和化学参数以及化合物的非侵入性递送，其中信号作为电磁波，无线电波，红外线等。要检测的参数之一包括使用在结膜和泪液膜中发现的化学变化和化学产物的非侵入性血液分析。安装在敷设在角膜或眼睛表面上的接触装置中的传感器能够评估和测量眼睛中的物理和化学参数，包括非侵入性血液分析。该系统利用眼罩运动和/或关闭眼罩来启动安装在接触装置中的微型射频敏感传感器。该信号可以通过电线或遥控的无线电通信到外部放置的接收器。然后可以处理，分析和存储信号。可以检测到几个参数，包括血液成分的全面无创分析，全身和眼部血流量的测量，心率和呼吸频率的测量，跟踪操作，排卵检测，辐射检测和药物作用，眼睛和全身性疾病等。

6. 发明申请

US20100145180A1 Apparatus for physical measurements of the eye 审中-公开
公开(公告)号：US20100145180A1
公开(公告)日：2010-06-10
申请号：US12591344
申请日：2009-11-17
申请人： Marcio Marc Abreu
发明人： Marcio Marc Abreu
IPC分类号： A61B3/16
CPC分类号： A61B3/10 , A61B3/0025 , A61B3/0058 , A61B3/1241 , A61B3/16 , A61B3/185 , A61B5/0002 , A61B5/01 , A61B5/031 , A61B5/14507 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1455 , A61B5/14555 , A61B5/1486 , A61B5/18 , A61B5/412 , A61B5/416 , A61B5/445 , A61B5/4839 , A61B5/6814 , A61B8/06 , A61B8/56 , A61B2560/0214 , A61B2560/0219 , A61B2560/0252 , A61B2560/0418 , A61B2562/0238 , A61B2562/12 , A61F9/0017 , A61F9/0026 , G02C7/04 , Y02A90/26
摘要： Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and/or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.

7. 发明申请

US20070142718A1 Noninvasive measurement of chemical substances 失效
标题翻译：无创测量化学物质
公开(公告)号：US20070142718A1
公开(公告)日：2007-06-21
申请号：US11601686
申请日：2006-11-20
申请人： Marcio Abreu
发明人： Marcio Abreu
IPC分类号： A61B5/00 , A61B6/00
CPC分类号： A61B3/10 , A61B3/0025 , A61B3/0058 , A61B3/1241 , A61B3/16 , A61B3/185 , A61B5/0002 , A61B5/01 , A61B5/031 , A61B5/14507 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1455 , A61B5/14555 , A61B5/1486 , A61B5/18 , A61B5/412 , A61B5/416 , A61B5/445 , A61B5/4839 , A61B5/6814 , A61B8/06 , A61B8/56 , A61B2560/0214 , A61B2560/0219 , A61B2560/0252 , A61B2560/0418 , A61B2562/0238 , A61B2562/12 , A61F9/0017 , A61F9/0026 , G02C7/04 , G06F19/00 , Y02A90/26
摘要： Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and/or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.
摘要翻译：利用放置在眼睛上的接触装置，以便根据这些物理和化学参数检测身体的物理和化学参数以及化合物的非侵入性递送，其中信号作为电磁波，无线电波，红外线等。要检测的参数之一包括使用在结膜和泪液膜中发现的化学变化和化学产物的非侵入性血液分析。安装在敷设在角膜或眼睛表面上的接触装置中的传感器能够评估和测量眼睛中的物理和化学参数，包括非侵入性血液分析。该系统利用眼罩运动和/或关闭眼罩来启动安装在接触装置中的微型射频敏感传感器。该信号可以通过电线或遥控的无线电通信到外部放置的接收器。然后可以处理，分析和存储信号。可以检测到几个参数，包括血液成分的全面无创分析，全身和眼部血流量的测量，心率和呼吸频率的测量，跟踪操作，排卵检测，辐射检测和药物作用，眼睛和全身性疾病等。

8. 发明授权

US07216985B2 Intelligent patient interface for ophthalmic instruments 有权
公开(公告)号：US07216985B2
公开(公告)日：2007-05-15
申请号：US10643280
申请日：2003-08-18
申请人： Kamran Siminou , Jeffrey Oliver
发明人： Kamran Siminou , Jeffrey Oliver
IPC分类号： A61B3/00
CPC分类号： A61B3/0083 , A61B3/10 , A61B3/185
摘要： An ophthalmic examination system comprising a headrest with a detection element, and an ophthalmic instrument (OI) having a microprocessor and a sensor in communication with the microprocessor. The sensor is configured to detect the presence of the detection element, and the headrest is configured for coupling to the OI.

9. 发明申请

US20050200707A1 Multi-purpose imaging apparatus and adaptors therefor 有权
标题翻译：多功能成像设备及其适配器
公开(公告)号：US20050200707A1
公开(公告)日：2005-09-15
申请号：US10983785
申请日：2004-11-08
申请人： Kanagasingam Yogesan , Ian Constable , Gabriel Suplewski , Jean-Pierre Guillon
发明人： Kanagasingam Yogesan , Ian Constable , Gabriel Suplewski , Jean-Pierre Guillon
IPC分类号： G01N21/64 , A61B1/227 , A61B1/233 , A61B1/24 , A61B3/00 , A61B3/10 , A61B3/12 , A61B3/135 , A61B3/14 , A61B5/00 , A61B5/103 , G03B15/00 , G03B15/02 , G03B17/56 , H04N5/225
CPC分类号： H04N5/225 , A61B1/00105 , A61B1/043 , A61B1/0607 , A61B1/0638 , A61B1/0684 , A61B1/227 , A61B1/24 , A61B3/0075 , A61B3/1208 , A61B3/135 , A61B3/185 , A61B5/0071 , A61B5/0088 , A61B5/441 , A61B2560/0431
摘要： Provided is a multi-purpose imaging apparatus (10) comprising a body (14) and imaging means (36) housed within the body (14). The body (14) is adapted to releasably engage an adaptor (12). The adaptor (12) has an aperture (108) extending therethrough that aligns with the optical axis (X) of the imaging means (36) when so engaged, such that at least a portion of the optical axis (X) is not obscured. The adaptor (12) also has optics for illuminating a subject within the optical axis (X) for diagnostic purposes.
摘要翻译：提供了一种多用途成像装置（10），包括容纳在主体（14）内的主体（14）和成像装置（36）。主体（14）适于可释放地接合适配器（12）。适配器（12）具有延伸穿过其中的孔（108），当孔接合时，该孔径与成像装置（36）的光轴（X）对准，使得光轴（X）的至少一部分不被遮蔽。适配器（12）还具有用于照射用于诊断目的的光轴（X）内的对象的光学器件。

10. 发明申请

US20040039297A1 Noninvasive measurement of chemical substances 有权
公开(公告)号：US20040039297A1
公开(公告)日：2004-02-26
申请号：US10423056
申请日：2003-04-25
发明人： Marcio Marc Abreu
IPC分类号： A61B013/00
CPC分类号： A61B3/10 , A61B3/0025 , A61B3/0058 , A61B3/1241 , A61B3/16 , A61B3/185 , A61B5/0002 , A61B5/01 , A61B5/031 , A61B5/14507 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1455 , A61B5/14555 , A61B5/1486 , A61B5/18 , A61B5/412 , A61B5/416 , A61B5/445 , A61B5/4839 , A61B5/6814 , A61B8/06 , A61B8/56 , A61B2560/0214 , A61B2560/0219 , A61B2560/0252 , A61B2560/0418 , A61B2562/0238 , A61B2562/12 , A61F9/0017 , A61F9/0026 , G02C7/04 , G06F19/00 , Y02A90/26
摘要： Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and/or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.

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