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1. 发明授权

US12044352B2 Floor stand and optical detection apparatus having such a floor stand 有权
公开(公告)号：US12044352B2
公开(公告)日：2024-07-23
申请号：US18115829
申请日：2023-03-01
申请人： Carl Zeiss Meditec AG
发明人： Jürgen Held , Lennart Blatt
IPC分类号： F16M11/20 , F16M11/06 , G02B7/00
CPC分类号： F16M11/2071 , F16M11/06 , G02B7/001 , F16M2200/08
摘要： The invention relates to a floor stand for an optical detection device, having a foot part comprising multiple bearing points or a planar standing surface that span a base plane, having a first stand arm which is pivotably connected to the foot part by a first joint on the foot part, and which is connected to a second stand arm by a second joint remote from the foot part, wherein the length of the first stand arm is dimensioned such that the distance between the base plane and the second joint is smaller than the sum of the maximum value for the eye level when seated and the maximum value for the length of the lower leg including the foot when the first stand arm is aligned at 45 degrees in relation to the base plane.

2. 发明授权

US12029486B2 Low cost fundus imager with integrated pupil camera for alignment aid 有权
公开(公告)号：US12029486B2
公开(公告)日：2024-07-09
申请号：US17277177
申请日：2019-09-24
申请人： Carl Zeiss Meditec, Inc. , Carl Zeiss Meditec AG
发明人： Jochen Straub , Robert Sprowl , Yuan Liu , Matthew J. Everett
IPC分类号： A61B3/12 , A61B3/00 , A61B3/15
CPC分类号： A61B3/12 , A61B3/0008 , A61B3/0033 , A61B3/158
摘要： A low cost fundus camera uses LED light sources placed adjacent the camera's imaging stop, and thereby eliminates the need for optics for introducing the light source to the camera's optical path. Lens reflex in the pupil relay is avoided by using only reflective optics in the pupil relay. Reflex from the LED is mitigated by actuating each LED separately, one at a time, and capturing a separate image with each actuated LED. Reflex-free regions of each captured image are extracted and combined to create a composite reflex-free image.

3. 发明授权

US12016798B2 Methods for characterizing a laser beam of a laser processing system, diaphragm assembly and laser processing system 有权
公开(公告)号：US12016798B2
公开(公告)日：2024-06-25
申请号：US17641575
申请日：2020-09-07
申请人： Carl Zeiss Meditec AG
发明人： Christian Deutsch , Gerard Antkowiak , Martin Hacker
IPC分类号： A61F9/008
CPC分类号： A61F9/00814 , A61F2009/00855 , A61F2009/00872
摘要： The claimed embodiments relate to methods for characterizing a laser beam (24) of a laser processing system (30). The method includes a) providing an aperture arrangement (10) with a plurality of apertures (14) in a work plane (300) of the laser processing system (30) such that the apertures (14) extend within the work plane (300). The method also includes b) scanning the laser beam (24) along a scanning direction (200) parallel to the work plane (300) across the aperture arrangement (10) in such a way that the laser beam (24) at least partially sweeps over the apertures (14). The method also includes c) determining a respective energy of the laser beam (24) transmitted through the apertures (14) during the scanning process, and d) determining an extent of the laser beam (24) along the scanning direction (200) using the determined energy of the laser beam (24) transmitted through a first aperture (14a) of the plurality of apertures (14) and determining an energy parameter of the laser beam (24) on the basis of the determined energy of the laser beam (24) transmitted through a second aperture (14b) of the plurality of apertures (14). In this case, the first aperture (14a) has a predetermined extent along the scanning direction (200), which is smaller than the mean diameter of the laser beam (24) in the work plane (300). In addition, a second aperture (14b) has an extent that is larger than the laser beam (24) in the work plane (300) and is designed to transmit the laser beam (24) essentially completely.

4. 发明授权

US12011394B2 Devices and methods for laser surgery of an eye, especially for keratoplasty 有权
公开(公告)号：US12011394B2
公开(公告)日：2024-06-18
申请号：US17602874
申请日：2020-04-07
申请人： Carl Zeiss Meditec AG , RESBIOMED TECHNOLOGIES OOD
发明人： Alexander Angelov Angelov , Yavor Petrov Angelov , Mark Bischoff , Robert Pomraenke
IPC分类号： A61F9/008 , A61F2/14
CPC分类号： A61F9/00831 , A61F2/142 , A61F9/00804 , A61F2009/00872 , A61F2009/00878 , A61F2009/00893
摘要： Devices and methods of laser surgery of an eye, especially for refractive surgery, preferably for keratoplasty. The invention includes a planning and control unit, a system for laser surgery of an eye and a planning and control method wherein a device coordinate system of the first laser device and a device coordinate system of the characterization device are coupled using registration and measurement data or model data of the lamella can be unambiguously registered to the device coordinate systems, further by a defined edge geometry of the lamella, an ametropia correction during the generation of the lamella and by taking into account the hydration condition of the lamella, as well as methods for surgery.

5. 发明公开

US20240180747A1 METHOD FOR CARRYING OUT A SYSTEM TEST OF A LASER PROCESSING SYSTEM, CONTROL UNIT AND LASER PROCESSING SYSTEM 审中-公开
公开(公告)号：US20240180747A1
公开(公告)日：2024-06-06
申请号：US18552216
申请日：2022-03-11
申请人： Carl Zeiss Meditec AG
发明人： Wolf Weimer , Gregor Stobrawa , Mark Bischoff
IPC分类号： A61F9/009 , A61B17/00 , G01M11/08
CPC分类号： A61F9/009 , G01M11/08 , A61B2017/00154 , A61B2017/00725
摘要： A method for carrying out a system test of a laser processing system is disclosed. The method includes the execution of a functional test of a control element of the laser processing system. The method further includes the determination of a variable parameter and the determination of an influence of the determined variable parameter on an intended execution of a laser processing by means of the laser processing system. The execution of the functional test of the control element and the determination of the variable parameter overlap at least partially in time.

6. 发明授权

US11992439B2 System for therapy of the eye by treating tissue using non-linear interaction 有权
公开(公告)号：US11992439B2
公开(公告)日：2024-05-28
申请号：US17226890
申请日：2021-04-09
申请人： Carl Zeiss Meditec AG
发明人： Thomas Nobis , Marco Hanft , Mark Bischoff
IPC分类号： A61F9/008 , A61B3/10
CPC分类号： A61F9/008 , A61B3/10 , A61F9/00825 , A61F2009/0087 , A61F2009/00872 , A61F2009/00887 , A61F2009/00889 , A61F2009/00897
摘要： A system for therapy of the eye by treating tissue with therapeutic radiation using nonlinear interaction. A laser device is provided, which delivers the therapeutic radiation. The therapeutic radiation is focussed by a focussing device in an image field, and xy scanners and z scanners shift the focus laterally and longitudinally within a treatment volume. The therapeutic radiation is either a second short pulse radiation or a first short pulse radiation, each of which have a spectral centroid within a wavelength range defined by the short pulse properties. The system is particularly corrected with regard to longitudinal chromatic aberrations and lateral chromatic aberrations such that the spectral characteristic curves of the two aberrations each have a local extreme within the wavelength ranges, and a certain tolerance within the wavelength ranges is not exceeded, therefore the characteristic curves are very shallow.

7. 发明公开

US20240120094A1 THEORY-MOTIVATED DOMAIN CONTROL FOR OPHTHALMOLOGICAL MACHINE-LEARNING-BASED PREDICTION METHOD 审中-公开
公开(公告)号：US20240120094A1
公开(公告)日：2024-04-11
申请号：US18263162
申请日：2022-01-26
申请人： Carl Zeiss Meditec AG , Technische Universität München
发明人： Hendrik BURWINKEL , Holger MATZ , Stefan SAUR , Christoph HAUGER
IPC分类号： G16H50/20 , G06N20/00
CPC分类号： G16H50/20 , G06N20/00
摘要： A computer-implemented method for determining the refractive power of an intraocular lens includes providing a physical model for determining refractive power and training a machine learning system with clinical ophthalmological training data and associated desired results to form a learning model for determining the refractive power. A loss function for training includes: a first component taking into account clinical ophthalmological training data and associated and desired results and a second component taking into account limitations of the physical model wherein a loss function component value is greater the further a predicted value of the refractive power during the training is from results of the physical model with the same clinical ophthalmological training data as input values. Moreover, the method includes providing ophthalmological data of a patient and predicting the refractive power of the intraocular lens to be used by means of the trained machine learning system.

8. 发明授权

US11953667B2 Device for actuator-driven adjustment of the magnification stages of a magnification selector 有权
公开(公告)号：US11953667B2
公开(公告)日：2024-04-09
申请号：US16638571
申请日：2018-08-23
申请人： Carl Zeiss Meditec AG
发明人： David Golz , Dietrich Martin , Ingo Koschmieder
IPC分类号： G02B21/00 , G02B21/02 , G02B23/00 , A61B3/135 , A61B90/20
CPC分类号： G02B21/025 , G02B23/00 , A61B3/135 , A61B90/20 , G02B21/0012
摘要： A device by which the magnification stages of a magnification selector based on Galilean telescope systems can be adjusted by a motor. The magnification selector has a sensor that transmits the currently magnification stage to a control unit; in the control unit, an assignment of the magnification stages present on the magnification selector to a sequence of the magnification stages, organized based on size, is stored. For the user, there are operating elements connected to the control unit for selecting a magnification stage. In order to set the magnification stage selected by the user via the operating elements, the magnification selector has an actuator, which is connected to the control unit to receive appropriate control signals. Although provided in particular for slit lamps and surgical microscopes having eyepieces, the solution can also be applied in other ophthalmological devices or devices from other technical fields.

9. 发明公开

US20240091065A1 APPARATUS AND METHOD FOR LENS SURGERY 审中-公开
公开(公告)号：US20240091065A1
公开(公告)日：2024-03-21
申请号：US17767960
申请日：2020-10-09
申请人： Carl Zeiss Meditec AG
发明人： Mario GERLACH
IPC分类号： A61F9/008
CPC分类号： A61F9/00834 , A61F2009/00844 , A61F2009/0087 , A61F2009/00872
摘要： An apparatus for refractive lens surgery on the human eye, including: a laser device for separating tissue of the eye lens and capsular bag in a focus of pulsed laser radiation, a focus positioning device for setting and adjusting a location of the focus, a measuring apparatus for gathering the relative position of the eye lens and capsular bag, and a control device which reads data from the measuring apparatus and controls the focus positioning device, and which is designed to define and specify a pattern for the focus to the focus positioning device, the pattern separating tissue layers in the eye lens for the purposes of generating an accommodation space for an intralenticular intraocular lens. The accommodation space includes a cutout for a dimensionally-stable lens body of the intraocular lens and a peripheral fastening region for fixing the dimensionally-stable lens body at a single, predetermined, axial position.

10. 发明公开

US20240085326A1 METHOD, COMPUTER PROGRAM AND DATA PROCESSING UNIT FOR PREPARING OBSERVATION OF FLUORESCENCE INTENSITY, METHOD FOR OBSERVING FLUORESCENCE INTENSITY, AND OPTICAL OBSERVATION SYSTEM 审中-公开
公开(公告)号：US20240085326A1
公开(公告)日：2024-03-14
申请号：US18238445
申请日：2023-08-25
申请人： Carl Zeiss Meditec AG
发明人： Alois Regensburger , Christoph Hauger
IPC分类号： G01N21/64 , G02B21/00
CPC分类号： G01N21/6428 , G01N21/6458 , G02B21/0012 , G01N2021/6439 , G01N2021/6478 , G01N2201/129
摘要： What is provided is a method for preparing the observation of a fluorescence intensity of fluorescence radiation of a fluorescent dye in an observation object (3) that comprises object regions (3A-H) that differ from one another in terms of their depth and/or their orientation, wherein the observation is intended to be implemented using an optical observation system (100) using which fluorescence radiation is able to be observed, provided that this has a certain minimum intensity. The method comprises the following steps:

determining the parameter value of at least one parameter which influences the observation of the fluorescence intensity, and
simulating the fluorescence intensity expected for the respective object regions (3A-H) on the basis of the determined parameter value of the at least one parameter and a model of the influence of the at least one parameter on the fluorescence intensity.

Within the scope of the simulation, a minimum concentration of the fluorescent dye is predefined and the fluorescence intensity expected with the minimum concentration is determined for each object region (3A-H) based on the simulation.
Also provided are a computer program, a computer-implemented method, a data processing unit (6) and an optical observation system (100) for preparing the observation of a fluorescence intensity of fluorescence radiation of a fluorescent dye in an observation object (3).

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