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1. 发明申请

US20190231187A1 2D MULTI-LAYER THICKNESS MEASUREMENT 审中-公开
公开(公告)号：US20190231187A1
公开(公告)日：2019-08-01
申请号：US16252818
申请日：2019-01-21
申请人： Topcon Corporation
发明人： Zhenguo Wang , Zaixing Mao , Kinpui Chan
IPC分类号： A61B3/10 , G01B11/06 , A61B3/14 , G06T7/00 , G06T11/60
CPC分类号： A61B3/101 , A61B3/1005 , A61B3/14 , A61B5/0075 , A61B5/1075 , G01B11/06 , G01B11/0633 , G06T7/0012 , G06T11/60 , G06T2207/30041
摘要： A method for measuring layer thicknesses of a multi-layer structure includes generating first and second 2D images of the structure, each image being generated by measuring an intensity of a reflection of incident lights, from different discrete narrow spectral bands, on the structure. Thicknesses for at least one layer of the structure are then determined based on the measured reflection intensities at those locations.

2. 发明申请

US20190150728A1 FULL-EYE ILLUMINATION OCULAR SURFACE IMAGING OF AN OCULAR TEAR FILM FOR DETERMINING TEAR FILM THICKNESS AND/OR PROVIDING OCULAR TOPOGRAPHY 审中-公开
公开(公告)号：US20190150728A1
公开(公告)日：2019-05-23
申请号：US16251332
申请日：2019-01-18
申请人： TearScience, Inc.
发明人： Stephen M. Grenon , Donald R. Korb
IPC分类号： A61B3/10 , G02B26/02 , A61B3/107 , A61B3/00 , A61B3/14
CPC分类号： A61B3/101 , A61B3/0008 , A61B3/0025 , A61B3/0058 , A61B3/1005 , A61B3/107 , A61B3/14 , G02B26/023
摘要： Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.

3. 发明申请

US20180242840A1 METHOD AND SYSTEM FOR PUPIL RETRO ILLUMINATION USING SAMPLE ARM OF OCT INTERFEROMETER 审中-公开
公开(公告)号：US20180242840A1
公开(公告)日：2018-08-30
申请号：US15908098
申请日：2018-02-28
申请人： AMO WaveFront Sciences, LLC
发明人： Richard J. Copland
IPC分类号： A61B3/10 , A61B5/00 , A61B3/00
CPC分类号： A61B3/102 , A61B3/0025 , A61B3/10 , A61B3/1005 , A61B3/101 , A61B3/107 , A61B3/14 , A61B5/0066 , G01B9/02017 , G01B9/02083
摘要： An optical measurement instrument includes optical coherence tomography (OCT) interferometer and a pupil retro illumination system which directs laser light onto the retina of an eye via the sample arm of the OCT interferometer. The laser light passes through an intraocular lens (IOL) implanted into the eye, and an iris camera captures an image of the eye from a portion of the light returned from the retina of the eye, the returned light also passing through the IOL. One or more fiducials of the IOL are detected from the captured image, and an angular orientation of the eye is ascertained from the one or more detected fiducials.

4. 发明申请

US20180107272A1 USER PHYSICAL ATTRIBUTE BASED DEVICE AND CONTENT MANAGEMENT SYSTEM 审中-公开
公开(公告)号：US20180107272A1
公开(公告)日：2018-04-19
申请号：US15790859
申请日：2017-10-23
申请人： PAYPAL, INC.
发明人： Ananya Das , Shaun Warman , Bryant Luk , Jason Ziaja , Christopher Diebold O'Toole
IPC分类号： G06F3/01 , A61B5/00 , A61B3/10 , A61B5/11 , G02B27/01 , A61B3/14 , G06T19/00 , H04L29/08 , A61B3/113 , G06K9/00
CPC分类号： G06F3/013 , A61B3/101 , A61B3/113 , A61B3/14 , A61B5/0077 , A61B5/1103 , A61B5/165 , A61B5/4824 , A61B5/486 , G02B27/0172 , G02B2027/0138 , G06K9/00302 , G06K9/00362 , G06T19/006 , G16H10/00 , H04L67/06 , H04L67/22 , H04L67/38
摘要： Systems and methods for device and content management include determining a user is viewing virtual reality content from a user device, and receiving, through a network from the user device, body information associated with the user while the user is viewing the virtual reality content. A user device management configuration associated with the body information is determined. A user device management action is retrieved using the user device management configuration. A notification associated with the user device management action that causes the user device to perform the user device management action and modify the virtual reality content being viewed by the user is sent through the network to the user device.

5. 发明授权

US09833138B2 Device for in-vivo determination of eye moisture 有权
公开(公告)号：US09833138B2
公开(公告)日：2017-12-05
申请号：US14458344
申请日：2014-08-13
申请人： Zvi Nachum
发明人： Zvi Nachum
IPC分类号： A61B5/053 , A61B3/10
CPC分类号： A61B3/101 , A61B5/053
摘要： A medical diagnostic device and method, the device including: (a) an alternating current source, adapted to produce an alternating current; (b) an electrode arrangement having at least first and second electrodes, separated by an electrically insulating region, the arrangement having an at least semi-rigid region that fixes the electrodes in a spaced-apart manner, the arrangement adapted to contact the soft tissue on the inner surface of the eyelid; and (c) a processor, associated with the electrode arrangement, said electrodes electrically connected to the alternating current source; wherein, when the electrode arrangement is provided with the alternating current, and is disposed against the soft tissue, the soft tissue electrically bridges between the electrodes to form an electrical circuit, wherein an electrical signal is produced by the alternating current electrically passing between the electrodes via the soft tissue; wherein the processor is adapted to receive in-vivo based electrical information originating from the electrical signal, via the circuit, and to produce an output relating to, or derived from, the moisture parameter, based on the in-vivo electrical information; and wherein the processor is designed and configured to compute the moisture parameter in the soft tissue, at least partially based on the in-vivo electrical information, and based on an empirical correlation between the in-vivo electrical information and the moisture parameter.

6. 发明授权

US09804416B2 Energizable ophthalmic lens with an event-based coloration system 有权
公开(公告)号：US09804416B2
公开(公告)日：2017-10-31
申请号：US13899510
申请日：2013-05-21
申请人： Johnson & Johnson Vision Care, Inc.
发明人： Randall B. Pugh , Karson S. Putt , Camille Higham , Sharika Snook
IPC分类号： G02C7/04 , A61B5/145 , G02C7/08 , G02C11/00 , A61B3/10 , G02C7/02 , A61B5/00
CPC分类号： G02C7/046 , A61B3/101 , A61B5/14507 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/6821 , A61B5/7445 , G02C7/021 , G02C7/04 , G02C7/083 , G02C11/10
摘要： The present invention provides a device for an energizable Ophthalmic Lens with an event coloration mechanism. The event coloration mechanism may color or change color based on some predefined event. For example, a predefined constituent or predefined condition of the tear fluid may be indicative of the predefined event, and the event coloration mechanisms may interact with the tear fluid, accordingly. The event coloration mechanism may provide the energizable functionality of the Ophthalmic Lens in some embodiments. In others, the event coloration mechanism may be passive but may interact and interface with the electrical components of the Ophthalmic Lens, such as, for example, those included within the Media Insert. Event coloration mechanisms may be combined with additional functionalities that may be included in an energizable Ophthalmic Lens.

7. 发明授权

US09782942B2 Methods and apparatus for positioning a structure on a polymer layer 有权
公开(公告)号：US09782942B2
公开(公告)日：2017-10-10
申请号：US14143842
申请日：2013-12-30
申请人： Verily Life Sciences LLC
发明人： Jeffrey George Linhardt , Daniel Patrick Barrows
IPC分类号： B29C31/00 , B29D11/00 , B29C65/00 , A61B3/10 , G02C7/04
CPC分类号： B29D11/00807 , A61B3/101 , B29C31/008 , B29C65/02 , B29C65/483 , B29C65/4835 , B29C65/4845 , B29C65/522 , B29C65/526 , B29C65/7811 , B29C65/7814 , B29C65/7844 , B29C66/1122 , B29C66/5324 , B29C66/5326 , B29C66/8122 , B29C66/81457 , B29C66/8161 , B29C66/8322 , B29C66/92451 , B29L2011/0041 , G02C7/04 , B29K2883/00 , B29K2867/003 , B29K2823/12 , B29K2875/00 , B29K2879/085
摘要： Methods and apparatus for positioning a structure on a polymer layer are described. A method may involve forming a first polymer layer. The method may further involve positioning, by an apparatus, a structure on the first polymer layer, where the apparatus comprises a rod having a first end that supports the structure as the structure is being positioned and a plunger located around the first end of the rod that presses the structure onto the first polymer layer as the structure is being positioned. And the method may involve forming a second polymer layer over the first polymer layer and the structure, where the first polymer layer defines a first side of a body-mountable device and the second polymer layer defines a second side of the body-mountable device opposite the first side.

8. 发明申请

US20170280992A1 FAST ABSOLUTE-REFLECTANCE METHOD FOR THE DETERMINATION OF TEAR FILM LIPID LAYER THICKNESS 审中-公开
公开(公告)号：US20170280992A1
公开(公告)日：2017-10-05
申请号：US15627077
申请日：2017-06-19
申请人： ABBOTT MEDICAL OPTICS INC.
发明人： Stanley W. Huth , Denise Tran
IPC分类号： A61B3/10 , G01J3/45 , G01B11/06 , A61B3/00
CPC分类号： A61B3/101 , A61B3/0025 , A61B3/1005 , G01B11/06 , G01J3/45
摘要： A method for determining reflectivity of a tear film lipid layer of a patient and recommending a course of treatment based on the same. The method includes the steps of: measuring a tear film aqueous plus lipid layer relative reflectance spectrum using a wavelength-dependent optical interferometer; converting the measured tear film aqueous plus lipid layer relative reflectance spectrum to a calculated absolute reflectance spectrum; comparing the calculated absolute reflectance spectrum to a theoretical absolute lipid reflectance spectrum to determine a tear film lipid layer thickness; and determining a reflectivity value for the tear film lipid layer thickness at a first wavelength of light corresponding to ultraviolet, violet, or blue light.

9. 发明授权

US09693682B2 Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film 有权
公开(公告)号：US09693682B2
公开(公告)日：2017-07-04
申请号：US14299504
申请日：2014-06-09
申请人： TearScience Inc.
发明人： Donald R. Korb , William L. Weber , Randal B. Chinnock , Benjamin T. Gravely , Stephen M. Grenon
IPC分类号： A61B3/14 , A61B3/10 , A61B3/02 , A61B5/05 , A61B3/00 , G06T7/00
CPC分类号： A61B3/101 , A61B3/0025 , A61B3/0041 , A61B3/1005 , A61B3/14 , G06T7/0012 , G06T2207/30041
摘要： Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).

10. 发明申请

US20170182192A1 METHOD OF DRY DYE DELIVERY FOR STAINING THE EYE 审中-公开
公开(公告)号：US20170182192A1
公开(公告)日：2017-06-29
申请号：US15459078
申请日：2017-03-15
申请人： Focal Point Technologies, LLC
发明人： Amir Sahba Jalali
IPC分类号： A61K49/00 , A61M35/00 , A61M11/02 , B65D83/14 , A61B3/10
CPC分类号： A61K49/006 , A61B3/101 , A61K9/0048 , A61K49/0043 , A61K49/0089 , A61M11/02 , A61M35/003 , A61M2202/064 , A61M2210/0612 , B65D83/20 , B65D83/32 , B65D83/752
摘要： A device and method for staining the eye of a patient in need of the same includes the introduction, onto the surface of the eye, of a dry powder form at a dye suitable for staining the eye. The dry powder form of the dye is introduced onto the surface of the eye without the use of a substrate at or near the eye's surface.

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