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1. 发明授权

US08481284B2 Process of preparing conjugates of allium organosulfur compounds with amino acids, peptides, and proteins 有权
标题翻译：有机硫化合物与氨基酸，肽和蛋白质的共轭物的制备方法
公开(公告)号：US08481284B2
公开(公告)日：2013-07-09
申请号：US12898006
申请日：2010-10-05
申请人： Kirk L. Parkin , Guodong Zhang
发明人： Kirk L. Parkin , Guodong Zhang
IPC分类号： C12P1/00 , C12P21/00 , C07K1/00 , C07C331/00
CPC分类号： C12P11/00 , A23L29/055 , A23L33/10 , A23L33/105 , C07C319/24 , C07C381/00 , C12P21/00 , C07C323/60 , C07C323/58
摘要： Processes using Allium tissue homogenates and extracts in a simple and cost-effective manner to maximize the yields and recovery of thiosulfinates from Allium tissues and related organisms possessing alliinase, LF synthase and/or S-alk(en)yl-L-cysteine sulfoxides are disclosed.
摘要翻译：使用大蒜组织匀浆和提取物的方法以简单且成本有效的方式使来自具有蒜氨酸酶，LF合酶和/或S-alk（en）yl -L-半胱氨酸亚砜的大蒜组织和相关生物体中硫代亚磺酸盐的产率和回收率最大化披露

2. 发明申请

US20030018063A1 Physiologically active agents containing vicinal dithioglycols and use thereof in various branches of economy 失效
公开(公告)号：US20030018063A1
公开(公告)日：2003-01-23
申请号：US10169367
申请日：2002-07-01
发明人： Sergei Mikhailovich Zenovich , Boris Khaimovich Strelets
IPC分类号： A61K031/185 , A61K031/19 , A61K031/095
CPC分类号： A23G3/36 , A21D2/08 , A21D13/80 , A23B4/20 , A23C2230/10 , A23K20/105 , A23K50/10 , A23K50/75 , A23L2/385 , A23L17/00 , A23L29/055 , A23L29/284 , A23L33/10 , A23V2002/00 , A61K8/46 , A61K8/466 , A61K9/0019 , A61K9/0024 , A61K9/0095 , A61K9/2095 , A61K31/095 , A61K2800/51 , A61K2800/522 , A61Q19/00 , C12G3/04 , A23V2250/30
摘要： The invention relates to the production of food and can be used to obtain food additives, biologically active food additives. The invention discloses the use of vicinal dithioglicol of general chemical formula RCH(SH)CH(SH)R1 as a food additive or a biologically active food additive having the property of binding carbonil compounds present in food products and the human body according to the reaction resulting in the formation of cyclic thioacetal or ketal which are easily removable from the human body as well as able to form complexes with ions of bivalent metals providing a physiologically beneficial effect on the transportation of said ions through sell membranes, on the glycolysis process, on the enzymatic catalysis process, on the catabolism of carbohydrate moiety of amino acids and on thiol-disulfide equilibrium in the metabolism of amino acids. As well as inhibiting undesirable processes in food products and human body. The invention also describes food additives, biologically active food additives, food products containing vicinal dithioglicol as well as processes for producing said additives and products. The technical result of the claimed technical solution is the use of vicinal dithioglicols as having immuno-corrective effect on human organism and stimulating a number of physiological processes and inhibiting undesirable processes in organisms and food products such as fatty acid peroxidation. On the ground of the above vicinal dithioglicols are used in food production to increase shelf life of products, to create new dietetic foodstuff, to increase biological value and activity of food, to enlarge the number of manufactured food additives and biologically active food additives. The invention also relates to cosmetology, particularly to medical cosmetology and dermatology. It can be used to prepare novel cosmetic agents, cosmetic means for treating skin by adding compounds selected from the group of vicinal dithioglicols as ingredients to cosmetic and/or dermatological preparations. Vicinal dithioglicols have a number of physiologically advantageous properties allowing to provide novel characteristics to cosmetic and dermatological means in relation to their action on skin and hair. The invention relates to a novel topical formulationnull To a method of using the formulation and to a method of producing the same. It relates to compositions able to improve the condition and appearance of skin and having medicinal and prophylactic effect on hair and nails. The invention also relates to agriculture, for instance for production of feed and mixed fodder or in veterinary. Vicinal dithioglicols can be used as physiologically active substances and active ingredients of feed additives and/or feed and/or of other preparations for domestic animals, poultry, and pets. The invention teaches to use at least one vicinal dithioglicol as an active ingredient of physiologically active means, feed additives, feed having immunity stimulating and antioxidant effect and chemical activity of irreversible binding and removing some widespread toxic compounds from organisms of animals and poultry, such as heavy and radioactive metal compounds including mercury, lead, polonium, caesium, bismuth, cobalt, cadmium, as well as arsenic and other toxins. Vicinal dithioglicols of the claimed preparations stimulate some important physiological processes in organisms of animals and poultry. The invention also discloses a feed additive, feed for animals and poultry and other means comprising this substance, methods of their production and administration.

3. 发明申请

US20160309761A1 STABILIZED STEVIOL GLYCOSIDE IN CONCENTRATED SYRUP 审中-公开
标题翻译：稳定性SYRUP中稳定的硫代葡萄糖苷
公开(公告)号：US20160309761A1
公开(公告)日：2016-10-27
申请号：US15104605
申请日：2014-12-04
申请人： CARGILL, INCORPORATED
发明人： Robert Joshua Brower, III , Ting liu Carlson , Aron Broman Erickson , Nathan Edward Knutson , Michael A. Porter
IPC分类号： A23L27/30 , A23L29/10 , A23L29/30
CPC分类号： A23L27/33 , A23L2/60 , A23L27/36 , A23L29/035 , A23L29/045 , A23L29/05 , A23L29/055 , A23L29/10 , A23L29/25 , A23L29/262 , A23L29/30 , A23V2002/00 , C07D311/22
摘要： A method for preparation of an acidic stabilized syrup concentrate containing rebaudioside B and a stabilizer additive. Acidic stabilized syrup concentrate compositions are also provided.
摘要翻译：一种制备含有莱鲍迪甙B和稳定剂添加剂的酸性稳定的糖浆浓缩物的方法。还提供酸性稳定的糖浆浓缩物组合物。

4. 发明申请

US20110319346A1 ELECTROSTATIC PROTEIN/GLUCOSINOLATE COMPLEXES 审中-公开
标题翻译：静电蛋白/葡糖淀粉复合物
公开(公告)号：US20110319346A1
公开(公告)日：2011-12-29
申请号：US13255729
申请日：2010-03-03
申请人： Koraljka Rade-Kukic , Christophe Joseph Etienne Schmitt
发明人： Koraljka Rade-Kukic , Christophe Joseph Etienne Schmitt
IPC分类号： A61K38/16 , A23L2/66 , A23J3/08 , A23L1/19 , A23L1/24 , A23L1/39 , A23D7/00 , A61P43/00 , A23L1/30
CPC分类号： A23D7/005 , A23L27/86 , A23L29/045 , A23L29/055 , A23L33/105 , A23L33/19 , A23V2002/00 , A23V2250/5424 , A23V2250/21 , A23V2200/16
摘要： The present invention relates to the field of electrostatic complexes. Embodiments of the present invention relate to food-grade electrostatic complexes containing at least one milk protein and at least one glucosinolate and to the uses of such complexes, e.g., to reduce the perceived bitterness of glucosinolates and/or to form and stabilize emulsions and/or foams.
摘要翻译：本发明涉及静电复合物领域。本发明的实施方案涉及含有至少一种乳蛋白质和至少一种硫代葡萄糖苷酸的食品级静电复合物以及这种复合物的用途，例如降低葡萄糖异硫氰酸酯的感觉到的苦味和/或形成和稳定乳液和/ 或泡沫。

5. 发明申请

US20110082282A1 PROCESS OF PREPARING CONJUGATES OF ALLIUM ORGANOSULFUR COMPOUNDS WITH AMINO ACIDS, PEPTIDES, AND PROTEINS 有权
标题翻译：用氨基酸，肽和蛋白质制备ALLIUM有机骨架化合物的结合方法
公开(公告)号：US20110082282A1
公开(公告)日：2011-04-07
申请号：US12898006
申请日：2010-10-05
申请人： Kirk L. Parkin , Guodong Zhang
发明人： Kirk L. Parkin , Guodong Zhang
IPC分类号： C12P21/00 , C07C381/00 , C07K5/083 , C07D207/16 , C07K14/47 , C07K14/465 , C07K14/415 , C07K14/76 , C12P11/00
CPC分类号： C12P11/00 , A23L29/055 , A23L33/10 , A23L33/105 , C07C319/24 , C07C381/00 , C12P21/00 , C07C323/60 , C07C323/58
摘要： Processes using Allium tissue homogenates and extracts in a simple and cost-effective manner to maximize the yields and recovery of thiosulfinates from Allium tissues and related organisms possessing alliinase, LF synthase and/or S-alk(en)yl-L-cysteine sulfoxides are disclosed.
摘要翻译：使用大蒜组织匀浆和提取物的方法以简单且成本有效的方式使来自具有蒜氨酸酶，LF合酶和/或S-alk（en）yl -L-半胱氨酸亚砜的大蒜组织和相关生物体中硫代亚磺酸盐的产率和回收率最大化披露

6. 发明授权

US07824705B2 Physiologically active agents containing vicinal dithioglycols and use thereof in various branches of economy 有权
公开(公告)号：US07824705B2
公开(公告)日：2010-11-02
申请号：US11732081
申请日：2007-04-02
申请人： Sergei Mikhailovich Zenovich , Boris Khaimovich Strelets
发明人： Sergei Mikhailovich Zenovich , Boris Khaimovich Strelets
IPC分类号： A61K47/00 , A61K9/70 , A61K9/20 , A23K1/17
CPC分类号： A23G3/36 , A21D2/08 , A21D13/80 , A23B4/20 , A23C2230/10 , A23K20/105 , A23K50/10 , A23K50/75 , A23L2/385 , A23L17/00 , A23L29/055 , A23L29/284 , A23L33/10 , A23V2002/00 , A61K8/46 , A61K8/466 , A61K9/0019 , A61K9/0024 , A61K9/0095 , A61K9/2095 , A61K31/095 , A61K2800/51 , A61K2800/522 , A61Q19/00 , C12G3/04 , A23V2250/30
摘要： The invention relates to the food and medical industries, medical cosmetics, dermatology, agriculture and the mixed feed industry. According to the invention vicinal dithioglycole (common formula RCH(SH)CH(SH)R−1 (I)) is used as a food additive, a food product, physiologically-active substances and active ingredients of forage additives and of forage, in cosmetic and/or dermatological and skin-therapeutic remedies. The invention comprises methods for producing such additives, products and remedies. The substance of formula (I) stimulates physiological processes, increases human and animal immunity, inhibits undesirable process in organisms and food products, produces curative and preventive action of skin, hair and nails and after vicinal dithioglycole is administered the intoxication effect of alcohol consumption known as hang-over is completely removed.

7. 发明授权

US07820196B2 Physiologically active agents containing vicinal dithioglycols and use thereof in various branches of economy 有权
标题翻译：含有邻位二硫代乙二醇的生理活性剂及其在各种经济部门中的应用
公开(公告)号：US07820196B2
公开(公告)日：2010-10-26
申请号：US11732080
申请日：2007-04-02
申请人： Sergei Mikhailovich Zenovich , Boris Khaimovich Strelets
发明人： Sergei Mikhailovich Zenovich , Boris Khaimovich Strelets
IPC分类号： A61K47/00 , A61K9/70 , A61K9/20 , A23K1/17
CPC分类号： A23G3/36 , A21D2/08 , A21D13/80 , A23B4/20 , A23C2230/10 , A23K20/105 , A23K50/10 , A23K50/75 , A23L2/385 , A23L17/00 , A23L29/055 , A23L29/284 , A23L33/10 , A23V2002/00 , A61K8/46 , A61K8/466 , A61K9/0019 , A61K9/0024 , A61K9/0095 , A61K9/2095 , A61K31/095 , A61K2800/51 , A61K2800/522 , A61Q19/00 , C12G3/04 , A23V2250/30
摘要： The invention relates to the food and medical industries, medical cosmetics, dermatology, agriculture and the mixed feed industry. According to the invention vicinal dithioglycole (common formula RCH(SH)CH(SH)R−1 (I)) is used as a food additive, a food product, physiologically-active substances and active ingredients of forage additives and of forage, in cosmetic and/or dermatological and skin-therapeutic remedies. The invention comprises methods for producing such additives, products and remedies. The substance of formula (I) stimulates physiological processes, increases human and animal immunity, inhibits undesirable process in organisms and food products, produces curative and preventive action of skin, hair and nails and after vicinal dithioglycole is administered the intoxication effect of alcohol consumption known as hang-over is completely removed.
摘要翻译：本发明涉及食品医疗工业，医药化妆品，皮肤病学，农业和混合饲料工业。根据本发明，邻位二硫代乙二醇（通式RCH（SH）CH（SH）R-1（I））用作食品添加剂，食品，生理活性物质和饲料添加剂和饲料中的活性成分化妆品和/或皮肤病学和皮肤治疗药物。本发明包括生产这些添加剂，产品和补救措施的方法。式（I）的物质刺激生理过程，增加人和动物免疫力，抑制生物体和食品中的不良过程，产生皮肤，毛发和指甲的治疗和预防作用，并且在连位二硫糖醇之后施用酒精消耗的中毒作用因为挂机被完全删除。

8. 发明授权

US11980644B2 Method of ingesting supplements in connection with an airplane flight 有权
公开(公告)号：US11980644B2
公开(公告)日：2024-05-14
申请号：US17155026
申请日：2021-01-21
申请人： Jet Renewal Kit, LLC
发明人： Patti Tveit Milligan
IPC分类号： A61K35/742 , A23L29/00 , A23L33/105 , A23L33/18 , A61K31/7028 , A61K36/31 , A61K36/534 , A61K36/752 , A61K36/9068 , A61K38/06
CPC分类号： A61K35/742 , A23L29/055 , A23L33/105 , A23L33/18 , A61K31/7028 , A61K36/31 , A61K36/534 , A61K36/752 , A61K36/9068 , A61K38/063
摘要： A method includes ingesting a first portion of a first supplement within three hours prior to boarding an airplane for a flight and ingesting a first portion of a second supplement within three hours prior to boarding an airplane for a flight. The method includes ingesting a second portion of the second supplement and ingesting a first portion of a third supplement during the flight. The method includes ingesting a second portion of the first supplement alongside a second portion of the third supplement within three hours of the airplane landing. The first supplement includes a probiotic. The second supplement includes an amount of at least one of gluconate, sorbitol, xylitol, maltodextrin, peppermint oil, lemon oil, lime oil, stevia leaf extract, ginger extract, steric acid, or probiotic. The third supplement includes at least one of glutathione, Brassica Oleracea sprouts, glucosinolates, glucoraphanin, or rice flour.

9. 发明授权

US11666549B2 Regulation of cancer using natural compounds and/or diet 有权
公开(公告)号：US11666549B2
公开(公告)日：2023-06-06
申请号：US16860153
申请日：2020-04-28
申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
发明人： Brent Allan Reynolds , Loic Pierre Deleyrolle
IPC分类号： A61K31/352 , A61K45/06 , A61K31/7028 , A61K36/31 , A61K31/12 , A61K31/26 , A61K31/353 , A23L29/00
CPC分类号： A61K31/352 , A23L29/035 , A23L29/055 , A61K31/12 , A61K31/26 , A61K31/353 , A61K31/7028 , A61K36/31 , A61K45/06 , A23V2002/00 , A61K31/7028 , A61K2300/00 , A61K31/26 , A61K2300/00 , A61K31/353 , A61K2300/00 , A61K31/12 , A61K2300/00
摘要： The current invention is directed to a treatment of a proliferative disease comprising administering to a subject in need of such treatment, a composition comprising epigallocatechin-3-gallate (EGCG), curcumin, glucosinolates and, optionally Daikon radish sprout, alone or in combination with providing a ketogenic diet or a modified ketogenic diet to the subject. The invention also provides a composition comprising medium chain triglycerides, Epigallocatechin-3-gallate, curcumin, compositions comprising glucosinolates and/or derivatives thereof, such as glucoraphanin and its breakdown product sulforaphane, (SFN) (which are found at high levels in broccoli sprouts or sprouts of other cruciferous vegetables), and, optionally Daikon radish sprout.

10. 发明申请

US20160038456A1 REGULATION OF CANCER USING NATURAL COMPOUNDS AND/OR DIET 审中-公开
标题翻译：使用天然化合物和/或饮食调节癌症
公开(公告)号：US20160038456A1
公开(公告)日：2016-02-11
申请号：US14775751
申请日：2014-03-12
申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
发明人： BRENT REYNOLDS , LOIC DELEYROLLE
IPC分类号： A61K31/352 , A61K31/7028 , A23L1/03 , A61K31/26 , A61K45/06 , A61K36/31 , A61K31/12
CPC分类号： A61K31/352 , A23L29/035 , A23L29/055 , A23V2002/00 , A61K31/12 , A61K31/26 , A61K31/353 , A61K31/7028 , A61K36/31 , A61K45/06 , A61K2300/00
摘要： The current invention is directed to a treatment of a proliferative disease comprising administering to a subject in need of such treatment, a composition comprising epigallocatechin-3-gallate (EGCG), curcumin, glucosinolates and, optionally Daikon radish sprout, alone or in combination with providing a ketogenic diet or a modified ketogenic diet to the subject. The invention also provides a composition comprising medium chain triglycerides, epigallocatechin-3-gallate, curcumin, compositions comprising glucosinolates and/or derivatives thereof, such as glucoraphanin and its breakdown product sulforaphane, (SFN) (which are found at high levels in broccoli sprouts or sprouts of other cruciferous vegetables), and, optionally Daikon radish sprout.
摘要翻译：本发明涉及增殖性疾病的治疗，包括向需要这种治疗的受试者施用包含表没食子儿茶素-3-没食子酸酯（EGCG），姜黄素，硫代葡萄糖苷和任选地Daikon萝卜芽的组合物，单独或与向受试者提供致生饮食或改良的生酮饮食。本发明还提供一种组合物，其包含中链甘油三酯，表没食子儿茶素-3-没食子酸酯，姜黄素，包含硫代葡萄糖苷和/或其衍生物的组合物，例如葡萄糖甙元及其分解产物萝卜硫素（SFN）（其在西兰花芽中高水平发现）或其他十字花科蔬菜的芽），以及任选的Daikon萝卜芽。

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