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1. 发明授权

US5683433A Implantable medical apparatus with magnifying header 失效
标题翻译：植入式医疗器具放大头
公开(公告)号：US5683433A
公开(公告)日：1997-11-04
申请号：US700187
申请日：1996-08-20
申请人： Dean F. Carson
发明人： Dean F. Carson
IPC分类号： A61N1/375
CPC分类号： A61N1/3752
摘要： An implantable medical apparatus operable in conjunction with an attachable lead, and having a housing containing an electronic component, with a header connected to the housing and defining a cavity. A connector element is positioned within the cavity and is operably connected to the electronic component. A lens is connected to the header, such that the connector element may be viewed through the lens to facilitate confirmation of proper connection of a lead to the connector. The header may be transparent, and the lens either formed as part of the header, or detachable therefrom.
摘要翻译：一种可植入医疗装置，其可与可附接的引线结合操作，并且具有容纳电子部件的外壳，其具有连接到所述外壳并限定空腔的插头。连接器元件定位在腔内并且可操作地连接到电子部件。透镜连接到集管，使得可以通过透镜观察连接器元件，以便于确认导线与连接器的正确连接。头部可以是透明的，并且透镜或者形成为头部的一部分，或者可以从头部拆卸。

2. 发明授权

US5534022A Lead having an integrated defibrillation/sensing electrode 失效
标题翻译：具有综合除颤/感测电极的引线
公开(公告)号：US5534022A
公开(公告)日：1996-07-09
申请号：US343293
申请日：1994-11-22
申请人： Drew A. Hoffmann , M. Elizabeth Bush
发明人： Drew A. Hoffmann , M. Elizabeth Bush
IPC分类号： A61N1/04 , A61N1/05
CPC分类号： A61N1/0563
摘要： An implantable defibrillator lead having an improved integrated bipolar defibrillation electrode is disclosed. The defibrillation electrode is electrically connected to the lead conductor at the distal end, and has an increased surface area portion at the distal end, for bipolar sensing with a right ventricular pacing electrode.
摘要翻译：公开了具有改进的集成双极除颤电极的可植入除颤器引线。除颤电极在远端电连接到引线导体，并且在远端具有增加的表面积部分，用于与右心室起搏电极进行双极感测。

3. 发明授权

US5534019A Cardiac defibrillator with case that can be electrically active or inactive 失效
标题翻译：心脏除颤器，可以电活动或不活动
公开(公告)号：US5534019A
公开(公告)日：1996-07-09
申请号：US353422
申请日：1994-12-09
申请人： Paul M. Paspa
发明人： Paul M. Paspa
IPC分类号： A61N1/375 , A61N1/39
CPC分类号： A61N1/3752 , A61N1/3956
摘要： A defibrillator having a housing for enclosing and containing defibrillation pulse generator circuitry, particularly adapted to allow for ease of manufacture and use. At least one surface of the housing is electrically conductive and connected to the defibrillation pulse generator circuitry for delivering defibrillating energy to the heart. The defibrillator is provided with a case-activating lead connector cavity having two isolated conductive elements. By tightening a first setscrew onto a lead connector pin, an electrode of the lead becomes active. Tightening a second setscrew activates the can. Tightening both setscrews onto a plug pin activates the can alone. To use neither a lead in the case-activating port, nor an active can, only one setscrew may be tightened onto a conductive or nonconductive pin to plug the cavity without activating the can. By using this system, various electrode configurations can be used as required to provide the optimum system for a given patient. The defibrillator generator housing is preferably implanted in the left pectoral region proximate the heart with the conductive surface facing the heart. Other implantable electrodes are discharged against the defibrillator generator housing electrode.
摘要翻译：一种除颤器，具有用于封闭并包含除颤脉冲发生器电路的壳体，特别适于允许制造和使用的容易性。壳体的至少一个表面是导电的并且连接到去纤维性颤动脉冲发生器电路，用于将去纤颤能量递送到心脏。除颤器设置有壳体激活引线连接器腔，其具有两个隔离的导电元件。通过将第一个固定螺丝拧紧到引线连接器引脚上，引线的电极变为有效。拧紧第二个固定螺丝激活罐。将两个固定螺丝拧紧到插头针上可以单独激活罐。为了不使用外壳启动端口中的引线，也不使用有源端子，只有一个固定螺丝可以拧紧到导电或不导电的引脚上，以在不启动外壳的情况下插入腔体。通过使用该系统，可以根据需要使用各种电极配置来为给定的患者提供最佳的系统。除颤器发生器壳体优选地植入靠近心脏的左胸部区域，导电表面面向心脏。其他可植入电极被排出到除颤器发生器壳体电极。

4. 发明授权

US5507779A Cardiac insulation for defibrillation 失效
标题翻译：心脏绝缘除颤
公开(公告)号：US5507779A
公开(公告)日：1996-04-16
申请号：US226742
申请日：1994-04-12
申请人： Peter A. Altman
发明人： Peter A. Altman
IPC分类号： A61B19/00 , A61N1/02 , A61N1/05 , A61N1/08 , A61N1/39
CPC分类号： A61N1/05 , A61N1/02 , A61N1/08 , A61N1/3918 , A61B2090/0815 , Y10S128/908
摘要： A defibrillation insulating device insulates the heart from the body. This forces current to flow through the heart without passing through surrounding tissues, thus increasing the current density throughout the heart, to depolarize the majority of the cardiac tissue with a minimum of energy.
摘要翻译：除颤绝缘装置将心脏与身体绝缘。这迫使电流流过心脏而不通过周围组织，从而增加整个心脏的电流密度，以最小的能量去除大部分心脏组织。

5. 发明授权

US5456706A Cardiac defibrillation lead having defibrillation and atrial sensing electrodes 失效
标题翻译：心脏除颤导联具有除颤和心房感应电极
公开(公告)号：US5456706A
公开(公告)日：1995-10-10
申请号：US177293
申请日：1994-01-04
申请人： Benjamin D. Pless , Drew A. Hoffmann , Michael B. Sweeney , M. Elizabeth Bush , Steven M. Mitchell
发明人： Benjamin D. Pless , Drew A. Hoffmann , Michael B. Sweeney , M. Elizabeth Bush , Steven M. Mitchell
IPC分类号： A61N1/05 , A61N1/39
CPC分类号： A61N1/0563 , A61N1/3956
摘要： A lead for use with an implantable cardioverter/defibrillator system is disclosed. In the preferred embodiment, the lead combines a right ventricular endocardial electrode, a superior vena cava electrode and one or more atrial sensing electrodes on a single catheter lead. The distal end of the lead is transvenously implanted, typically through an incision in the cephalic or subclavian vein. The proximal end of the lead is then tunneled below the fascia to the location of the pulse generator. Ventricular sensing and/or pacing electrode(s) may also be included at the distal end of the combined lead to provide ventricular intracardiac electrogram sensing and bradycardia pacing.
摘要翻译：公开了一种用于植入式心律转复/除颤器系统的引导件。在优选实施例中，引线将单个导管引线上的右心室心内膜电极，上腔静脉电极和一个或多个心房感测电极组合。导管的远端经常植入，通常通过头部或锁骨下静脉中的切口。引线的近端然后在筋膜下方隧道穿过脉冲发生器的位置。心室感应和/或起搏电极也可以包括在组合导联的远端，以提供心室心电图检测和心动过缓起搏。

6. 发明授权

US5439483A Method of quantifying cardiac fibrillation using wavelet transform 失效
标题翻译：使用小波变换量化心脏颤动的方法
公开(公告)号：US5439483A
公开(公告)日：1995-08-08
申请号：US139953
申请日：1993-10-21
申请人： Minh Duong-Van
发明人： Minh Duong-Van
IPC分类号： A61N1/39 , G06F17/00 , A61B5/046 , A61N1/36
CPC分类号： A61N1/3956
摘要： The present invention provides a system and method for characterizing cardiac fibrillation using wavelet transforms. By characterizing the seriousness of a fibrillation episode, a defibrillation shock may be delivered to the heart with less excess energy than conventional ICDs. A wavelet transform is performed on a digitized ECG using a second derivative weight function and the results are analyzed for missing "peaks" in the data. The more serious the fibrillation, the more peaks will be missing from the data. This information may then used to modify the voltage of the defibrillation shocks as a function of the seriousness of the fibrillation.
摘要翻译：本发明提供了使用小波变换来表征心脏颤动的系统和方法。通过表征纤维性颤动发作的严重性，可以以比常规ICD更少的过量能量将除颤休克递送至心脏。使用二阶导数权函数对数字化ECG进行小波变换，并对数据中缺少的“峰值”进行分析。纤维化越严重，数据峰将越多。然后可以使用该信息作为原纤维化严重性的函数来修改除颤电击的电压。

7. 发明授权

US5439004A Device and method for chaos based cardiac fibrillation detection 失效
标题翻译：基于混沌心脏颤动检测的装置和方法
公开(公告)号：US5439004A
公开(公告)日：1995-08-08
申请号：US173797
申请日：1993-12-23
申请人： Minh Duong-Van , Mark J. Meltzer
发明人： Minh Duong-Van , Mark J. Meltzer
IPC分类号： A61B5/046 , G06F17/00
CPC分类号： A61B5/046
摘要： A system and method for detecting ventricular fibrillation based on chaos theory. A Poincare plot of the amplitude of the ECG signal is generated and used to detect the presence of fibrillation. The plot is monitored for the data points drifting off the plot axes. Upon detecting such drift, the presence of ventricular fibrillation is confirmed. The system and method may be used as a primary detection scheme or as a backup system to reconfirm fibrillation detection using conventional techniques.
摘要翻译：一种基于混沌理论检测心室颤动的系统和方法。产生ECG信号幅度的庞加莱图，并用于检测原纤维的存在。监测从绘图轴漂移的数据点的情节。在检测到这种漂移时，证实了心室颤动的存在。系统和方法可以用作主要检测方案或作为备用系统，以使用常规技术重新确认原纤维化检测。

8. 发明授权

US5352239A Apparatus for producing configurable biphastic defibrillation waveforms 失效
标题翻译：用于产生可配置的双峰除颤波形的装置
公开(公告)号：US5352239A
公开(公告)日：1994-10-04
申请号：US37482
申请日：1993-03-24
申请人： Benjamin Pless
发明人： Benjamin Pless
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3906 , A61N1/3912
摘要： A programmable implantable medical device utilizable for delivering a configurable defibrillation waveform to a heart. The device includes defibrillation electrode means adapted to be connected to the heart for delivering a multiphasic defibrillation waveform thereto. A programmable waveform generator connected to the heart generates the multiphasic waveform such that at least one phase of the defibrillation waveform has programmed constant tilt.
摘要翻译：一种可编程可植入医疗装置，其可用于将可配置的除颤波形传送至心脏。所述装置包括适于连接到心脏的除颤电极装置，用于向其递送多相除颤波形。连接到心脏的可编程波形发生器产生多相波形，使得除颤波形的至少一个相位被编程为恒定的倾斜。

9. 发明授权

US5290299A Double jaw apparatus for attaching implanted materials to body tissue 失效
标题翻译：用于将植入材料附着到身体组织的双颚装置
公开(公告)号：US5290299A
公开(公告)日：1994-03-01
申请号：US16484
申请日：1993-02-09
申请人： Eric S. Fain , Mary E. Bush
发明人： Eric S. Fain , Mary E. Bush
IPC分类号： A61B17/128 , A61B17/28 , A61B17/00
CPC分类号： A61B17/1285 , A61B2017/2929 , Y10S227/902
摘要： A system is provided for fastening an implantable medical device, for example a defibrillator lead, to the heart. A lead electrode is placed in a desired position against the pericardium, pericardial tissue is grasped with a fastening tool, and the pericardial tissue is drawn away from epicardium and toward the fastening tool. A fastening member is applied to the pericardial tissue and to the lead electrode to secure the lead in the desired position. The application tool comprises a first pair of jaws for grasping membranous tissue and drawing the tissue away from other tissues and toward the tool. A second pair of jaws is provided for holding fastener members and delivering the fastener members to the membranous tissue.
摘要翻译：提供了一种用于将可植入医疗装置（例如除颤器引线）紧固到心脏的系统。将引线电极放置在针对心包的期望位置，心包组织用紧固工具抓住，并将心包组织从心外膜拉出并朝向紧固工具。将紧固构件施加到心包组织和引线电极，以将引线固定在期望的位置。应用工具包括用于抓住膜组织并将组织远离其他组织并朝向工具拉出的第一对钳口。提供第二对钳口用于保持紧固件并将紧固件传送到膜组织。

10. 发明授权

US5131388A Implantable cardiac defibrillator with improved capacitors 失效
标题翻译：具有改进电容器的可植入心脏除颤器
公开(公告)号：US5131388A
公开(公告)日：1992-07-21
申请号：US669646
申请日：1991-03-14
申请人： Benjamin D. Pless , William H. Elias , Timothy A. Marguit
发明人： Benjamin D. Pless , William H. Elias , Timothy A. Marguit
IPC分类号： A61N1/375 , A61N1/39
CPC分类号： A61N1/3956 , A61N1/375
摘要： An implantable cardiac defibrillator is provided having an energy source, a capacitor, and means coupled to the energy source for charging the capacitor. The capacitor comprises a planar layered structure of anode plates, cathode plates and means separating the anode plates and cathode plates. A polymeric envelope containing electrolyte encloses the layered structure. Electrical contact means extend from the anodes and cathodes to outside the envelope.

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