专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20100152419A1 FUSION PROTEIN CONTAINING HIGHLY-EXPRESSED AND SECRETED INSULIN PRECURSOR, DNA ENCODING SAME, AND METHOD OF PRODUCING INSULIN 审中-公开
标题翻译：含有高表达和分泌胰岛素前体的融合蛋白，编码其的DNA及其生产胰岛素的方法
公开(公告)号：US20100152419A1
公开(公告)日：2010-06-17
申请号：US12162473
申请日：2008-02-12
申请人： Seiji Sato , Masa-aki Kondo , Toshiyuki Kudo , Ko-suke Endo
发明人： Seiji Sato , Masa-aki Kondo , Toshiyuki Kudo , Ko-suke Endo
IPC分类号： C07K14/62 , C07H21/04 , C12N15/63 , C12N1/21 , C12P21/02
CPC分类号： C07K14/62 , C07K2319/01
摘要： A DNA which encodes a fused protein containing an insulin precursor of the overexpression secretion type for producing transgenic insulin, and a method of producing insulin with the use of this DNA.
摘要翻译：编码含有用于产生转基因胰岛素的过表达分泌型胰岛素前体的融合蛋白的DNA，以及使用该DNA生产胰岛素的方法。

2. 发明授权

US5461145A Sexing method of bovine embyros 失效
标题翻译：牛的embyros的性别的方法
公开(公告)号：US5461145A
公开(公告)日：1995-10-24
申请号：US984044
申请日：1992-12-02
申请人： Toshiyuki Kudo , Yoshiaki Itagaki , Seiji Sato , Shizuyo Sutou , Toyoo Nakamura
发明人： Toshiyuki Kudo , Yoshiaki Itagaki , Seiji Sato , Shizuyo Sutou , Toyoo Nakamura
IPC分类号： C12N15/09 , C12Q1/68 , C07H21/04 , C12P19/34
CPC分类号： C12Q1/6879
摘要： The present invention provides PCR primers with which sexing of bovine embryos can be easily attained and provides a practical, rapid and reliable method for determining the sex of bovine embryos using these primers. The methods for determining the sex of the bovine embryos are characterized by discriminating PCR products which are obtained by amplifying specific DNA sequences by PCR with pairs of male-specific and gender-neutral primers. These primers are derived from DNAs which specifically hybridize to the bovine male genome and from DNAs which gender-neutrally hybridize to both bovine male and female genomes.
摘要翻译：本发明提供可以容易地获得牛胚胎性别的PCR引物，并提供使用这些引物确定牛胚胎性别的实用，快速和可靠的方法。用于确定牛胚胎性别的方法的特征在于区分通过用雄性特异性和性别中性引物的PCR扩增特异性DNA序列获得的PCR产物。这些引物衍生自与牛雄性基因组特异性杂交的DNA，以及与牛雄性和雌性基因组性别中性杂交的DNA。

3. 发明授权

US06841361B1 Methods of producing recombinant insulin from novel fused proteins 失效
标题翻译：从新型融合蛋白生产重组胰岛素的方法
公开(公告)号：US06841361B1
公开(公告)日：2005-01-11
申请号：US09959548
申请日：2000-04-26
申请人： Shusaku Oka , Seiji Sato , Naohiko Higashikuni , Masaaki Kondo , Toshiyuki Kudo , Shigeaki Watanabe , Yoshihiro Waki , Hirotaka Yuki
发明人： Shusaku Oka , Seiji Sato , Naohiko Higashikuni , Masaaki Kondo , Toshiyuki Kudo , Shigeaki Watanabe , Yoshihiro Waki , Hirotaka Yuki
IPC分类号： C12N15/09 , C07K14/575 , C07K14/62 , C07K19/00 , C12N1/21 , C12N15/00 , C12N15/17 , C12P21/02 , C12R1/08 , C12P21/04
CPC分类号： C07K14/62 , C07K14/575 , C07K2319/00
摘要： This invention relates to a DNA encoding a fusion protein of formula (I) [Y]-[X1]-[B-chain]-[X2]-[Linker]-[X3]-[A-chain] (I) wherein Y is a leader peptide sequence for the expression and secretion of the protein, comprising at least one amino acid residue; X1 is an amino acid sequence which is cleavable enzymatically or chemically; B-chain is the amino acid sequence of insulin B chain; X2 is an amino acid sequence which is cleavable enzymatically; Linker is a linker sequence comprising at least one amino acid residue; X3 is an amino acid sequence which is cleavable enzymatically; and A- chain is the amino acid sequence of insulin A chain, and to a method for producing insulin using an expression system containing the DNA in high efficiency and high yield.
摘要翻译：本发明涉及编码式（I）的融合蛋白的DNA，其中Y是蛋白质的表达和分泌的前导肽序列，其包含至少一个氨基酸残基; X1是可酶切或化学切割的氨基酸序列 B链是胰岛素B链的氨基酸序列; X2是可酶切的氨基酸序列;接头是包含至少一个氨基酸残基的接头序列; X3是可酶切的氨基酸序列; A链是胰岛素A链的氨基酸序列，以及使用含有高效率和高收率的DNA的表达系统来生产胰岛素的方法。

4. 发明申请

US20040242141A1 Spinal cord removing apparatus and carcass tilting device therefor 审中-公开
标题翻译：脊髓去除装置及其胎体倾斜装置
公开(公告)号：US20040242141A1
公开(公告)日：2004-12-02
申请号：US10849980
申请日：2004-05-20
申请人： ITOHAM FOODS INC.
发明人： Shiro Ono , Koji Kusumoto
IPC分类号： A22C018/00
CPC分类号： A22B5/201 , A22B5/0005
摘要： A carcass tilting device equipped in a spinal cord removing apparatus for suctioning and removing spinal cord from spinal cavity of a carcass of slaughtered cattle, to facilitate removing spinal cord from the carcass suspended with its head down in a vertically narrow space, comprises a support column 21, a tilting member 23 pivotally mounted on the support column 21 and having a contact portion 25a with which the carcass makes contact, and a second cylinder 29 configured to cause the tilting member 23 to pivot to be tilted with respect to a vertical direction such that a lower end of the tilting member is raised. The tilting member 23 has an inner member 24 and an outer member 25 which are displaceable in the longitudinal direction from a position where the members 24 and 25 overlap each other, thereby causing the tilting member 23 to entirely extend.
摘要翻译：一种装备在脊髓去除装置中的胴体倾斜装置，用于从被屠宰的牲畜的屠体的脊髓腔抽吸和移除脊髓，以便于将脊髓从垂直狭窄的空间中向下悬挂的胎体中去除，包括支柱如图21所示，倾斜构件23可枢转地安装在支撑柱21上并且具有与胎体接触的接触部分25a和构造成使得倾斜构件23枢转以相对于垂直方向倾斜的第二气缸29，倾斜构件的下端升高。倾斜构件23具有内部构件24和外部构件25，其从构件24和25彼此重叠的位置在纵向方向上移位，从而使倾斜构件23完全延伸。

5. 发明授权

US5856303A Peptide, a bronchus-expanding agent, and a blood-flow-improving agent 失效
标题翻译：肽，支气管扩张剂和血液流动改善剂
公开(公告)号：US5856303A
公开(公告)日：1999-01-05
申请号：US776815
申请日：1997-02-07
申请人： Kazuhisa Kashimoto , Yumiko Nagano
发明人： Kazuhisa Kashimoto , Yumiko Nagano
IPC分类号： A61K38/00 , A61P7/00 , C07K14/575 , C07K14/605 , C07K5/00 , C07K7/00
CPC分类号： C07K14/605 , C07K14/575 , C07K14/57563 , A61K38/00
摘要： The present invention relates to a peptide represented by the general formula (1): ##STR1## wherein A is Ala or Gly; B is Ile or Val; C is Asn or Ser; D is Thr or Ser; E is Leu or Tyr; each of F, I and J is Lys or Arg, and at least one of F, I and J is Arg; G is Met, Leu or Nle; K is Asn or Ala; L is Ser or Ala; M is Ile or Val; and N is --NH.sub.2 or Asn--NH.sub.2, excluding the combination where A is Ala, B is Val, C is Asn, D is Thr, E is Leu, K is Asn, L is Ser, M is Ile, and N is Asn--NH.sub.2, and pharmaceutically acceptable salts thereof, as well as to a bronchus-expanding agent or a blood-flow-improving agent comprising said peptide or a pharmaceutically acceptable salt thereof as an active ingredient.
摘要翻译： PCT No.PCT / JP96 / 01543 Sec。 371日期1997年2月7日 102（e）1997年2月7日PCT PCT 1996年6月6日PCT公布。出版物WO96 / 41814 PCT 日期：1996年12月27日本发明涉及由通式（1）表示的肽：HHisSerAspABPheThrAspCTyrD（1）ArgEArgFGlnGAlaValIJTyrLeuKLMLeuN其中A为Ala或Gly; B是Ile或Val; C是Asn或Ser; D是Thr或Ser; E是Leu或Tyr; F，I和J各自为Lys或Arg，F，I和J中的至少一个为Arg; G为Met，Leu或Nle; K为Asn或Ala; L是Ser或Ala; M是Ile或Val; N为-NH 2或Asn-NH 2，不包括A为Ala的组合，B为Val，C为Asn，D为Thr，E为Leu，K为Asn，L为Ser，M为Ile，N为Asn -NH 2及其药学上可接受的盐，以及包含所述肽或其药学上可接受的盐作为活性成分的支气管扩张剂或血液流动改进剂。

6. 发明授权

US07396674B2 Reaction vessel 失效
标题翻译：反应容器
公开(公告)号：US07396674B2
公开(公告)日：2008-07-08
申请号：US11690033
申请日：2007-03-22
申请人： Junji Miyakawa , Asami Matsumoto , Shusaku Oka
发明人： Junji Miyakawa , Asami Matsumoto , Shusaku Oka
IPC分类号： C12M1/34
CPC分类号： B01L3/502746 , B01L3/50273 , B01L2200/0621 , B01L2200/0631 , B01L2200/0689 , B01L2300/0681 , B01L2300/069 , B01L2300/0832 , B01L2300/126 , B01L2300/1877 , B01L2300/1894 , B01L2400/0406 , B01L2400/0457 , B01L2400/0694 , B01L2400/084 , G01N33/54366 , Y10S435/81 , Y10S436/81
摘要： Reaction vessel 1 for assaying of a subject substrate molecule comprises a translucent narrow tube 2 which has a liquid feed port 4 at one end, and which is intended to be packed with microparticles 5 as solid phase support on which a reagent molecule is bound thereto, in which said reagent is capable of binding to, adsorbing, or showing affinity with the subject substrate molecule, and a effluent collecting tube 3 in which a liquid absorbing member 13 is provided inside for absorbing the liquid poured into the narrow tube, and which is connected to the narrow tube 2 at its downstream via a communicating passage 11, and a current-controlling mechanism for controlling liquid current in the narrow tube so as to hold the liquid in the narrow tube 2 during a predetermined time.
摘要翻译：用于测定受试衬底分子的反应容器1包括半透明的窄管2，其在一端具有一个液体供给口4，并且其中装有作为其上结合有试剂分子的固相载体的微粒5，其中所述试剂能够与所述基底分子结合，吸附或显示亲和性;以及流出物收集管3，其中在内部设置有液体吸收构件13以吸收流入所述窄管中的液体，并且其通过连通通道11在其下游连接到窄管2;以及电流控制机构，用于控制窄管中的液流，以在预定时间内将液体保持在窄管2中。

7. 发明授权

US6046168A Peptide inhibits blood triglyceride level 失效
标题翻译：肽抑制血液甘油三酯水平
公开(公告)号：US6046168A
公开(公告)日：2000-04-04
申请号：US981384
申请日：1997-12-23
申请人： Kyoichi Kagawa , Chizuko Fukuhama , Hisako Matsutaka , Toyoo Nakamura , Masahiro Numata , Shigeaki Watanabe , Kazuhisa Honda
发明人： Kyoichi Kagawa , Chizuko Fukuhama , Hisako Matsutaka , Toyoo Nakamura , Masahiro Numata , Shigeaki Watanabe , Kazuhisa Honda
IPC分类号： A23C9/152 , A23G1/00 , A23G1/42 , A23G1/44 , A23K1/16 , A23K1/18 , A23L1/305 , A61K38/00 , C07K5/083 , C07K5/08 , A61K38/06 , A61K38/08 , C07K7/06
CPC分类号： A23G1/44 , A23C9/1526 , A23G1/423 , A23K20/147 , A23K50/80 , A23L33/18 , C07K5/0808 , A61K38/00
摘要： The present invention relates to a peptide having the amino acid sequence shown in the sequence listing; an agent for inhibiting elevations of triglyceride levels in blood comprising the above peptide, a peptide Val-Tyr-Pro and/or a peptide Val-Thr-Leu as an active component; a food for specified health use which is endowed with a function of inhibiting elevations of triglyceride levels in blood by comprising these peptides as an active component; and a feed which is endowed with a function of inhibiting elevations of triglyceride levels in blood by comprising these peptides as an active component. According to the present invention, it becomes possible to prevent or treat obesity and hyperlipemia in humans and animals as well as cardiovascular diseases such as hypertension and arteriosclerosis associated therewith. Furthermore, it becomes possible to improve the meat quality of livestock and hatchery fish.
摘要翻译： PCT No.PCT / JP95 / 01264 Sec。 371 1997年12月23日第 102（e）日期1997年12月23日PCT提交1995年6月23日PCT公布。第WO97 / 00890号公报日期1997年1月9日本发明涉及具有序列表所示氨基酸序列的肽。包含上述肽，肽Val-Tyr-Pro和/或肽Val-Thr-Leu作为活性成分的血液中甘油三酯水平升高的药剂; 具有通过包含这些肽作为活性组分而具有抑制血液中甘油三酯水平升高的功能的用于特定健康用途的食物; 以及具有通过包含这些肽作为活性成分而抑制血液中甘油三酯水平升高的功能的饲料。根据本发明，可以预防或治疗人和动物中的肥胖症和高脂血症以及与其相关的心血管疾病如高血压和动脉硬化。此外，可以提高牲畜和孵化场的鱼肉质量。

8. 发明授权

US5958885A Peptide and formulations thereof inhibiting elevations of triglyceride levels in blood 失效
标题翻译：肽及其制剂抑制血液中甘油三酯水平的升高
公开(公告)号：US5958885A
公开(公告)日：1999-09-28
申请号：US973539
申请日：1997-11-24
申请人： Kyoichi Kagawa , Hisako Matsutaka , Chizuko Fukuhama , Hiroaki Fujino , Masahiro Numata , Kazuhisa Honda , Toyoo Nakamura
发明人： Kyoichi Kagawa , Hisako Matsutaka , Chizuko Fukuhama , Hiroaki Fujino , Masahiro Numata , Kazuhisa Honda , Toyoo Nakamura
IPC分类号： A23K1/16 , A23L1/305 , A61K38/00 , A61P3/04 , A61P3/06 , C07K1/20 , C07K5/103 , C07K14/415 , C07K5/10 , C07K7/04
CPC分类号： C07K5/101 , A23K20/147 , A23L33/18 , A61K38/00 , Y10S514/909
摘要： The present invention relates to a peptide having an amino acid sequence of Val-Val-Tyr-Pro as well as an agent for inhibiting elevation of triglyceride levels in blood, a food for specified health use (the so-called physiologically functional food) and a feed comprising the above peptide as an active component. According to the present invention, a peptide inhibiting elevation of triglyceride levels in blood as well as an agent for inhibiting elevation of triglyceride levels in blood, a physiologically functional food and a feed, all comprising the peptide as an active component are obtained. With these products of the invention, it becomes possible to prevent or treat obesity and hyperlipemia of human and animals as well as circulatory system diseases such as hypertension and arteriosclerosis associated therewith. Furthermore, the materials of the invention make it possible to improve the meat quality of livestock and hatchery fish.
摘要翻译： PCT No.PCT / JP96 / 01570 Sec。 371日期：1997年11月24日 102（e）1997年11月24日PCT PCT 1996年6月10日PCT公布。第WO97 / 35875号公报日期：1997年10月2日本发明涉及具有Val-Val-Tyr-Pro的氨基酸序列的肽以及用于抑制血液中甘油三酯水平升高的药剂，用于特定健康用途的食物（所谓的生理功能食品）和包含上述肽作为活性成分的饲料。根据本发明，获得抑制血液中甘油三酯水平升高的肽以及抑制血液中甘油三酯水平升高的药剂，生理功能性食品和饲料，其全部包含肽作为活性成分。利用本发明的这些产品，可以预防或治疗人类和动物的肥胖症和高脂血症以及与其相关的循环系统疾病如高血压和动脉硬化。此外，本发明的材料可以提高牲畜和孵化场的肉质。

9. 发明授权

US2440851A Electron discharge device of the magnetron type 失效
公开(公告)号：US2440851A
公开(公告)日：1948-05-04
申请号：US52551544
申请日：1944-03-08
申请人： RCA CORP
发明人： DONAL JR JOHN S , BROWN BARREMORE B , LOUIS CUCCIA CARMEN
IPC分类号： H01J23/22 , H01J25/587
CPC分类号： H01J23/22 , H01J25/587

10. 发明授权

US08778088B2 Foreign matter removal device, foreign matter removal method and foreign matter removal system 有权
标题翻译：异物去除装置，异物去除方法和异物去除系统
公开(公告)号：US08778088B2
公开(公告)日：2014-07-15
申请号：US13012150
申请日：2011-01-24
申请人： Takeshi Nishimoto , Masaya Ichihara , Yo Komatsu , Satoshi Mashiba , Suguru Sakuramoto , Shinji Shimamura , Ryuzo Urakami
发明人： Takeshi Nishimoto , Masaya Ichihara , Yo Komatsu , Satoshi Mashiba , Suguru Sakuramoto , Shinji Shimamura , Ryuzo Urakami
IPC分类号： B08B7/04 , B08B3/04 , B65G49/04
CPC分类号： B08B3/102 , A22C17/08
摘要： A foreign matter removal device 10 preliminary cleans the work 50 in a bucket 12 housed in an input tank 15, then further cleans the work 50 in buckets 13, 14 housed in cleaning tanks 16, 17 by agitating cleaning liquid while inverting the buckets to transfer the work to a subsequent bucket. Particularly, the bottom of the cleaning tank is formed such that the nearer to a center of the bottom, the deeper the bottom becomes. The cleaning liquid overflowing from the cleaning tanks are stored in auxiliary tanks 22, 23. First and second ejection units 29a, 29b are arranged at different heights in the cleaning tank to generate a circulating flow in the cleaning liquid.
摘要翻译：异物去除装置10预先清理容纳在输入箱15中的铲斗12中的工件50，然后通过搅拌清洗液体同时倒转桶来转移，从而清洁容纳在清洁罐16,17中的桶13,14中的工件50 工作到后续的桶。特别地，清洗槽的底部形成为更靠近底部的中心，底部越深。从清洗槽溢出的清洗液被储存在辅助罐22,23中。第一和第二喷射单元29a，29b布置在清洁槽中的不同高度处，以在清洗液中产生循环流。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式