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1. 发明授权

US5857997A Catheter for electrophysiological procedures 失效
标题翻译：导管用于电生理程序
公开(公告)号：US5857997A
公开(公告)日：1999-01-12
申请号：US919137
申请日：1997-08-30
申请人： William W. Cimino , Robert Abrams , Miriam H. Taimisto , Marc Jenson , Patrick E. Macaulay
发明人： William W. Cimino , Robert Abrams , Miriam H. Taimisto , Marc Jenson , Patrick E. Macaulay
IPC分类号： A61B5/042 , A61B17/00 , A61B18/00 , A61B18/14 , A61M25/01 , A61M37/00
CPC分类号： A61B5/6855 , A61B18/00 , A61B18/1492 , A61B5/0422 , A61M25/0136 , A61B2017/00044 , A61B2017/00292 , A61B2017/00853 , A61B2018/00916 , A61B2018/1253 , A61B2562/0209 , A61B2562/043 , A61M25/0144 , A61M25/0147
摘要： A catheter adapted to perform electrophysiological procedures comprises a body member, a manipulation handle attached to the proximal end of the body member for applying torque to the body member, the handle having a control knob adapted for control movements in a first plane and in a second plane simultaneously. A deflection control line is attached at its distal end to the distal portion of the catheter and its proximal end attached to the control device of the handle so that tension applied to the control line by sliding the control knob causes deflection of the distal portion of the catheter. A stiffening member is disposed within the body member of the catheter and is slidable, said stiffening member providing increased rigidity to the portion of the body member in which the stiffening member is located. Rotation of the control knob controls the position of the stiffening member in the body member. In a further aspect, a stiffening member in accordance with one embodiment includes a tapered distal end section with a ball formed on the distal tip, the tapered section terminating at the ball. In accordance with another aspect, the torsional rigidity of the catheter body is increased by use of a layer of aramid fibers mixed with an epoxy. In yet another feature, the handle and rotatable sliding element are symmetrically shaped to facilitate complete single-handed operation of the handle by the physician of all position control aspects of the catheter.
摘要翻译：适于执行电生理过程的导管包括身体构件，附接到身体构件的近端的操纵手柄，用于向身体构件施加扭矩，手柄具有适于控制第一平面中的运动的控制旋钮，飞机同时进行。偏转控制线在其远端附接到导管的远端部分，并且其近端附接到手柄的控制装置，使得通过滑动控制旋钮施加到控制线的张力导致远端部分的偏转导管。加强构件设置在导管的主体构件内并且可滑动，所述加强构件为加强构件所在的主体构件的部分提供增加的刚性。控制旋钮的旋转控制加强构件在主体构件中的位置。在另一方面，根据一个实施例的加强构件包括锥形远端部分，其具有形成在远侧末端上的球，锥形部分终止于球。根据另一方面，通过使用与环氧树脂混合的芳族聚酰胺纤维层来增加导管体的扭转刚度。在另一个特征中，手柄和可旋转的滑动元件是对称的，以便于医生对导管的所有位置控制方面的手柄的完全单手操作。

2. 发明授权

US5741320A Catheter control system having a pulley 失效
标题翻译：具有滑轮的导管控制系统
公开(公告)号：US5741320A
公开(公告)日：1998-04-21
申请号：US433229
申请日：1995-05-02
申请人： Peter Thornton , Tracy D. Maahs , Robert C. Hayzelden , Miriam H. Taimisto
发明人： Peter Thornton , Tracy D. Maahs , Robert C. Hayzelden , Miriam H. Taimisto
IPC分类号： A61M25/01 , A61M25/092 , A61M37/00
CPC分类号： A61M25/0144 , A61M25/0136 , A61M25/0147 , A61M2025/015
摘要： A steerable catheter comprising a resilient body member, a manipulation handle attached to the proximal end of the body member, a control wire extending from the handle to the distal end of the catheter for deflection control, and a pulley mechanism for controlling the movement of the control wire. Longitudinal movement of a slide element in the handle causes movement of the control wire and control over the deflection of the distal end of the catheter. The pulley mechanism is connected between the slide element and the control wire to provide greater mechanical advantage to effect deflection of the body member while enhancing deflection control resolution. A stiffening member is also disposed in the catheter body member and its position is controlled by the rotational motion of the slide element. The position of the pulley mechanism is not affected by rotational motion of the slide element.
摘要翻译：一种可导向导管，包括弹性体构件，附接到主体构件的近端的操纵手柄，从手柄延伸到导管的远端以用于偏转控制的控制线，以及用于控制主体构件的运动的滑轮机构控制线。滑动元件在手柄中的纵向运动引起控制线的移动并控制导管远端的偏转。滑轮机构连接在滑动元件和控制线之间，以提供更大的机械优点来实现主体部件的偏转，同时增强偏转控制分辨率。加强构件也设置在导管本体构件中，并且其位置由滑动元件的旋转运动控制。滑轮机构的位置不受滑动元件的旋转运动的影响。

3. 发明授权

US5735280A Ultrasound energy delivery system and method 失效
标题翻译：超声能量输送系统及方法
公开(公告)号：US5735280A
公开(公告)日：1998-04-07
申请号：US708829
申请日：1996-09-09
申请人： Marshall L. Sherman , Thomas M. Castellano
发明人： Marshall L. Sherman , Thomas M. Castellano
IPC分类号： A61B18/00 , A61B17/00 , A61B17/22 , A61B8/00
CPC分类号： A61B17/2202 , A61B2017/00084 , A61B2017/00092 , A61B2017/00243
摘要： An energy delivery system and method controls the frequency of the power driving an ultrasonic device to achieve more efficient power delivery. During operation of the ultrasonic device to deliver power to a patient site, the system and method automatically sweeps the drive power through a frequency range, locates the series and parallel resonance frequencies, calculates the average of those frequencies and locks the power generator at that average frequency to drive the crystal. This frequency sweep procedure occurs automatically when the ultrasonic crystal is located at the patient site and the power generator operator presses the power-on switch to apply power. The method of tuning the power generator thus occurs when the crystal is at the site temperature and is transparent to the operator. The application of an external bio-layer to the crystal increases its bandwidth and its robustness. Mounting a temperature sensor or sensors at the crystal permits monitoring of the crystal temperature and allows drive level control over the power generator to control the temperature at the crystal.
摘要翻译：能量输送系统和方法控制驱动超声波装置的功率的频率以实现更有效的功率传递。在超声波设备运行期间向病人现场输送电力时，系统和方法会自动扫描驱动电源频率范围，定位串联和并联谐振频率，计算出这些频率的平均值，并将发电机锁定在该平均值频率驱动晶体。当超声波晶体位于患者现场时，该频率扫描过程自动发生，发电机操作者按下电源开关以施加电力。因此，当晶体处于现场温度并且对操作者是透明的时，调谐发电机的方法发生。外部生物层在晶体上的应用增加了其带宽和其鲁棒性。将温度传感器或传感器安装在晶体处可以监控晶体温度，并允许对发电机进行驱动电平控制，以控制晶体的温度。

4. 发明授权

US5596995A Biomedical device having a temperature sensing system 失效
标题翻译：具有温度感测系统的生物医学装置
公开(公告)号：US5596995A
公开(公告)日：1997-01-28
申请号：US432837
申请日：1995-05-02
申请人： Marshall L. Sherman , Thomas M. Castellano , Jose J. Moya
发明人： Marshall L. Sherman , Thomas M. Castellano , Jose J. Moya
IPC分类号： A61B5/00 , A61B5/01
CPC分类号： A61B5/01
摘要： A system for monitoring temperature comprising a first thermocouple temperature sensor mounted to a catheter, the catheter also having a connector with a plurality of connecting devices for making the thermocouple signals available to external equipment. The connecting devices are formed of a material dissimilar to at least one of the thermocouple leads such that a second thermocouple is created at the connection point. The second thermocouple produces a second temperature signal that combines with the signal from the first thermocouple. A reference temperature sensor is mounted at the connector to sense the temperature at the connector and provide a reference temperature signal for use by a processor in correcting the combined temperature signal to derive the first thermocouple signal received from the connector.
摘要翻译：一种用于监测温度的系统，包括安装到导管的第一热电偶温度传感器，所述导管还具有连接器，所述连接器具有用于使热电偶信号可用于外部设备的多个连接装置。连接装置由不同于至少一个热电偶引线的材料形成，使得在连接点处形成第二热电偶。第二个热电偶产生与第一个热电偶信号相结合的第二个温度信号。参考温度传感器安装在连接器处以感测连接器处的温度，并提供参考温度信号，供处理器用于校正组合温度信号以导出从连接器接收的第一热电偶信号。

5. 发明授权

US5810740A System and method for analyzing electrogram waveforms 失效
标题翻译：用于分析电描记图波形的系统和方法
公开(公告)号：US5810740A
公开(公告)日：1998-09-22
申请号：US815672
申请日：1997-03-12
申请人： William Lee Paisner
发明人： William Lee Paisner
IPC分类号： A61B5/042 , A61B5/0402
CPC分类号： A61B5/6852 , A61B5/0422
摘要： An electrogram analysis system and method for determining the quality of information gathered from electrical signals in biological tissue. The system comprises a catheter having an array of at least two electrodes at its distal end, the electrodes detecting electrical signals emanating from the site of origin and providing relayed signals to a processor. The processor processes the relayed signals into waveforms and computes a quality of the relayed signals. The quality of the relayed signals is used to select higher quality signals for further analysis, such as site of origin determination and mapping. The relayed signals from the electrodes may also be used to determine a quality for a particular electrode channel. When the invention is used in cardiac applications, the relayed signal quality may comprise two components--a channel quality and a beat quality. The channel quality represents the value of information received from a particular electrode and channel, while the beat quality represents the value of a particular heart beat across all channels. The signal quality is displayed to the user. In cardiac applications, the channel quality can be displayed in a format corresponding to the shape of the electrode array, with channel quality from each electrode positioned in a corresponding position on the display. The display may also show the waveforms of the signal, such as the heart beat waveform in a cardiac procedure.
摘要翻译：一种用于确定从生物组织中的电信号收集的信息的质量的电描记图分析系统和方法。该系统包括在其远端具有至少两个电极的阵列的导管，电极检测从原点位置发出的电信号，并向处理器提供中继信号。处理器将中继信号处理成波形并计算中继信号的质量。中继信号的质量用于选择较高质量的信号进行进一步分析，如原点确定和映射。来自电极的中继信号也可用于确定特定电极通道的质量。当本发明用于心脏应用时，中继的信号质量可以包括两个组件 - 信道质量和节拍质量。信道质量表示从特定电极和信道接收的信息的值，而节拍质量表示所有信道上的特定心跳的值。信号质量显示给用户。在心脏应用中，可以以对应于电极阵列的形状的格式显示通道质量，其中来自每个电极的通道质量位于显示器上的相应位置。显示器还可以显示信号的波形，例如心脏手术中的心跳波形。

6. 发明授权

US5681280A Catheter control system 失效
标题翻译：导管控制系统
公开(公告)号：US5681280A
公开(公告)日：1997-10-28
申请号：US434003
申请日：1995-05-02
申请人： Scott J. Rusk , Eugene J. Jung, Jr. , Wade A. Bowe , John A. Simpson
发明人： Scott J. Rusk , Eugene J. Jung, Jr. , Wade A. Bowe , John A. Simpson
IPC分类号： A61B18/14 , A61M25/01 , A61M25/092
CPC分类号： A61M25/0147 , A61B18/1492 , A61M25/0136 , A61B2018/00214 , A61B2018/00916 , A61M2025/015
摘要： A steerable catheter comprising a resilient deflectable body member having an expandable electrode array at the distal end thereof, and a manipulation handle attached to the proximal end of the body member, the handle including an array deployment device. A mandrel is movable through the shaft of the catheter by control movements at the handle to deploy the array or collapse the array as selected. A displacement compensation system is operatively connected to the mandrel such that when the array is expanded, the compensation system biases the mandrel so keep the array expanded, even during instances of deflection of the distal end. Similarly, the displacement compensation system biases the mandrel to keep the array collapsed when that configuration is selected, even during instances of straightening of the catheter. The displacement compensation system also compensates for overturning the control device in the handle to protect the array and deployment systems.
摘要翻译：一种可导向的导管，其包括在其远端处具有可扩张电极阵列的弹性可偏转主体构件和附接到主体构件的近端的操纵手柄，所述手柄包括阵列展开装置。心轴可以通过导管的轴移动，通过手柄处的控制运动来部署阵列或者按选择折叠阵列。位移补偿系统可操作地连接到心轴，使得当阵列膨胀时，补偿系统偏压心轴，使得即使在远端的偏转的实例期间也使阵列扩张。类似地，即使在导尿管矫正的情况下，位移补偿系统也会偏心心轴以保持阵列在选择该构型时收缩。位移补偿系统还补偿了手柄中的控制装置的翻转，以保护阵列和展开系统。

7. 发明授权

US5666970A Locking mechanism for catheters 失效
标题翻译：导管锁定机构
公开(公告)号：US5666970A
公开(公告)日：1997-09-16
申请号：US433228
申请日：1995-05-02
申请人： Iain S. R. Smith
发明人： Iain S. R. Smith
IPC分类号： A61M25/01 , A61B5/00
CPC分类号： A61M25/0144 , A61M25/0136 , A61M25/0147 , A61B2018/00916 , A61M2025/015
摘要： A locking mechanism for a steerable catheter, the catheter comprising a resilient body member having a restoring force that tends to maintain the body member at a predetermined orientation, and a manipulation handle including a control element and a second element movable in relation to one another and adapted for controlling the orientation of the body member. The locking mechanism maintains the selected deflection of the body member against the restoring force but permits a physician to overcome the locking force by moving the control element. The locking mechanism does not interfere with the other control movement of the handle. The locking device has a biasing member and a contact member mounted between the control element and the second element. The biasing member urges the contact member into frictional contact with one of the elements for holding the control element at the selected longitudinal position.
摘要翻译：一种用于可导向导管的锁定机构，所述导管包括弹性本体构件，所述弹性体构件具有倾向于将身体构件保持在预定取向的恢复力，以及操纵手柄，其包括可相对于彼此移动的控制元件和第二元件，适于控制身体构件的取向。锁定机构保持身体构件的选定的偏转抵抗恢复力，但允许医师通过移动控制元件来克服锁定力。锁定机构不会干扰手柄的其他控制运动。锁定装置具有偏置构件和安装在控制元件和第二元件之间的接触构件。偏置构件推动接触构件与用于将控制元件保持在所选择的纵向位置的元件之一摩擦接触。

8. 发明授权

US5662606A Catheter for electrophysiological procedures 失效
标题翻译：导管用于电生理程序
公开(公告)号：US5662606A
公开(公告)日：1997-09-02
申请号：US339125
申请日：1994-11-14
申请人： William W. Cimino , Robert Abrams , Miriam H. Taimisto , Marc Jenson , Patrick E. Macaulay
发明人： William W. Cimino , Robert Abrams , Miriam H. Taimisto , Marc Jenson , Patrick E. Macaulay
IPC分类号： A61B5/0408 , A61B5/0402 , A61B5/042 , A61B5/0478 , A61B5/0492 , A61B17/00 , A61B18/00 , A61B18/12 , A61B18/14 , A61M25/00 , A61M25/01 , A61M37/00
CPC分类号： A61B5/0422 , A61B18/00 , A61B18/1492 , A61B5/6852 , A61B5/6855 , A61M25/0136 , A61M25/0144 , A61M25/0147 , A61B2017/00039 , A61B2017/00044 , A61B2017/00292 , A61B2017/003 , A61B2017/00853 , A61B2018/0016 , A61B2018/00351 , A61B2018/00577 , A61B2018/00839 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/1253 , A61B2562/0209 , A61B2562/043 , A61M25/0043 , A61M25/0054
摘要： A catheter adapted to perform electrophysiological procedures comprises a body member, a manipulation handle attached to the proximal end of the body member for applying torque to the body member, the handle having a control knob adapted for control movements in a first plane and in a second plane simultaneously. A deflection control line is attached at its distal end to the distal portion of the catheter and its proximal end attached to the control device of the handle so that tension applied to the control line by sliding the control knob causes deflection of the distal portion of the catheter. A stiffening member is disposed within the body member of the catheter and is slidable, said stiffening member providing increased rigidity to the portion of the body member in which the stiffening member is located. Rotation of the control knob controls the position of the stiffening member in the body member. In a further aspect, a stiffening member in accordance with one embodiment includes a tapered distal end section with a ball formed on the distal tip, the tapered section terminating at the ball. In accordance with another aspect, the torsional rigidity of the catheter body is increased by use of a layer of aramid fibers mixed with an epoxy. In yet another feature, the handle and rotatable sliding element are symmetrically shaped to facilitate complete single-handed operation of the handle by the physician of all position control aspects of the catheter.
摘要翻译：适于执行电生理过程的导管包括身体构件，附接到身体构件的近端的操纵手柄，用于向身体构件施加扭矩，手柄具有适于控制第一平面中的运动的控制旋钮，飞机同时进行。偏转控制线在其远端附接到导管的远端部分，并且其近端附接到手柄的控制装置，使得通过滑动控制旋钮施加到控制线的张力导致远端部分的偏转导管。加强构件设置在导管的主体构件内并且可滑动，所述加强构件为加强构件所在的主体构件的部分提供增加的刚性。控制旋钮的旋转控制加强构件在主体构件中的位置。在另一方面，根据一个实施例的加强构件包括锥形远端部分，其具有形成在远侧末端上的球，锥形部分终止于球。根据另一方面，通过使用与环氧树脂混合的芳族聚酰胺纤维层来增加导管体的扭转刚度。在另一个特征中，手柄和可旋转的滑动元件是对称的，以便于医生对导管的所有位置控制方面的手柄的完全单手操作。

9. 发明授权

US5606974A Catheter having ultrasonic device 失效
标题翻译：导管具有超声波装置
公开(公告)号：US5606974A
公开(公告)日：1997-03-04
申请号：US434004
申请日：1995-05-02
申请人： Thomas M. Castellano , Robert C. Hayzelden , Tracy D. Maahs
发明人： Thomas M. Castellano , Robert C. Hayzelden , Tracy D. Maahs
IPC分类号： A61B17/00 , A61B17/22 , A61B8/12
CPC分类号： A61B17/2202 , A61B2017/00084 , A61B2017/00092 , A61B2017/00243
摘要： A catheter includes a piezoelectric transducer mounted to the distal end of a catheter. In one embodiment, the piezoelectric transducer has the shape of a cylinder and in another embodiment, a convex shape with a mounting flange. In the cylindrical shape, a plurality of surface mounted temperature sensors are disposed within the piezoelectric transducer. The sensors are electrically insulated and a sealing technique prevents the leakage of body fluids from penetrating the interior of the catheter through the sensor bores. The cylindrical transducer is supported on mounting members so that it is accurately mounted and sealed while at the same time, the material used does not significantly dampen the transducer. The convex shape includes a temperature sensor at its tip.
摘要翻译：导管包括安装到导管的远端的压电换能器。在一个实施例中，压电换能器具有圆筒的形状，在另一实施例中，具有安装凸缘的凸形。在圆筒形状中，多个表面安装温度传感器设置在压电换能器内。传感器是电绝缘的，并且密封技术防止体液泄漏通过传感器孔穿透导管内部。圆柱形换能器支撑在安装构件上，使其精确安装和密封，同时所使用的材料不会显着损坏换能器。凸形包括其顶端的温度传感器。

10. 发明授权

US5492119A Catheter tip stabilizing apparatus 失效
标题翻译：导管尖端稳定装置
公开(公告)号：US5492119A
公开(公告)日：1996-02-20
申请号：US172039
申请日：1993-12-22
申请人： Robert M. Abrams
发明人： Robert M. Abrams
IPC分类号： A61N1/05 , A61B5/04
CPC分类号： A61N1/0573
摘要： Electrophysiology catheter apparatus including at least one retractable control wire with a preformed curved resilient foot formed at the distal extremity, slidably advanced and retracted within a longitudinal lumen of a catheter tube for controllably anchoring to a selected endocardial heart tissue. The proximal end of the control wire is formed with a handle to be grasped to slidably advance the preformed resilient foot beyond the distal tip of a catheter to project laterally to contact the adjacent tissue.
摘要翻译：电生理学导管装置，其包括至少一个可缩回的控制线，其具有形成在远端的预成形的弯曲弹性脚，可滑动地前进并在导管管的纵向内腔内缩回，用于可控地锚定到选定的心内膜心脏组织。控制线的近端形成有待抓握的手柄，以将预成型的弹性脚可滑动地推进超过导管的远侧末端以横向突出以接触邻近的组织。

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