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1. 发明授权

US6041662A Process and apparatus for the determination of true average peak velocity 失效
标题翻译：用于确定真实平均峰值速度的过程和设备
公开(公告)号：US6041662A
公开(公告)日：2000-03-28
申请号：US923579
申请日：1997-09-04
申请人： Rolf Jenni
发明人： Rolf Jenni
IPC分类号： A61B8/06 , G01S7/52 , G01S7/521 , G01S15/58 , G01S15/89 , G01F1/66
CPC分类号： G01S15/58 , G01S15/8979 , G01S7/52004 , G01S7/5205
摘要： A procedure for the determination of the true average peak velocity of particulate laden liquids in a tube, by the use of a Doppler ultrasonic transducer inserted in said tube. The average peak velocity (APV) and the null and first moment (M0 or M1) of the entire spectrum are obtained. The measured correlation between the null or first moment (M0 or M1) and APV are compared with a corresponding standard value which represents the correlation between M0 or M1 and APV upon optimal positioning of the Doppler ultrasonic transducer whereby where there is a deviation from the standard value, the transducer is moved until the values coincide.
摘要翻译：通过使用插入所述管中的多普勒超声波换能器来确定管中颗粒负载液体的真实平均峰值速度的程序。获得整个频谱的平均峰值速度（APV）和零和第一时刻（M0或M1）。将零或第一时刻（M0或M1）和APV之间的测量相关性与表示多普勒超声换能器的最佳定位时的M0或M1与APV之间的相关性的相应标准值进行比较，其中与标准偏差值，传感器被移动直到值重合。

2. 发明授权

US5167233A Dilating and imaging apparatus 失效
标题翻译：放置和成像设备
公开(公告)号：US5167233A
公开(公告)日：1992-12-01
申请号：US638192
申请日：1991-01-07
申请人： Michael J. Eberle , John M. Hodgson
发明人： Michael J. Eberle , John M. Hodgson
IPC分类号： A61B8/12 , A61M29/02
CPC分类号： A61M25/104 , A61B8/12 , A61B8/445 , A61M2025/1079
摘要： A dilating and imaging apparatus for attaching to and receiving pressurized fluid from a distal end of a catheter. The apparatus includes an inflatable balloon and an imaging device positioned behind an expandable portion of the balloon and upstream of the flow of pressurized fluid into the balloon so as to enable the balloon to deflate and achieve a smaller diameter than that of the imaging device, thus enabling the apparatus to enter a stenosis having a smaller diameter than the imaging device. In one embodiment of the invention, the imaging device can be maneuvered within the balloon while the balloon is inflated and dilating the stenosis.
摘要翻译：一种用于从导管的远端附接和接收加压流体的扩张和成像装置。该装置包括可膨胀的气囊和位于气囊的可膨胀部分后面的加压流体流入气囊的上游的成像装置，以使气囊能够放气并获得比成像装置更小的直径，因此使装置能够进入具有比成像装置更小的直径的狭窄。在本发明的一个实施例中，成像装置可以在球囊充气并扩张狭窄的同时在气囊内操纵。

3. 发明授权

US06123673A Method of making an ultrasound transducer assembly 有权
标题翻译：制造超声波换能器组件的方法
公开(公告)号：US06123673A
公开(公告)日：2000-09-26
申请号：US324692
申请日：1999-06-02
申请人： Michael J. Eberle , Gary P. Rizzuti , Horst F. Kiepen
发明人： Michael J. Eberle , Gary P. Rizzuti , Horst F. Kiepen
IPC分类号： A61B8/06 , A61B8/12 , A61B8/14 , B06B1/02 , B06B1/06 , G01S15/89 , G10K11/00
CPC分类号： A61B8/06 , A61B8/12 , A61B8/4483 , A61B8/4488 , A61B8/4494 , B06B1/0633 , B06B1/067 , B06B1/0674 , G01S15/892 , G01S15/8979 , G01S15/899 , G10K11/004 , G10K11/008 , A61B8/445 , B06B2201/76 , G01S15/8981 , Y10T29/42
摘要： An ultrasound catheter is disclosed for providing substantially real-time images of small cavities. The ultrasound catheter is characterized by separate and distinct materials for backing the transducers and for carrying the electronics components. The separate materials comprise an electronics carrier meeting the requirements for holding the integrated circuitry of the ultrasound device and a backing material displaying superior characteristics relating to reducing ringing and minimizing the effect of other sources of signal degradation in the transducer assembly. Also, in accordance with the present invention, a technique is described for connecting the conductor lines of the separate transducer assembly and electronics body.
摘要翻译：公开了一种用于提供基本上实时的小空腔图像的超声波导管。超声导管的特征在于分离和不同的材料，用于支撑换能器和携带电子部件。单独的材料包括满足用于保持超声波装置的集成电路的要求的电子载体，以及显示与减少振铃有关的优异特性并使传感器组件中的其它信号劣化的影响最小化的背衬材料。此外，根据本发明，描述了用于连接单独的换能器组件和电子体的导体线的技术。

4. 发明授权

US5938615A Ultrasound catheter probe 失效
标题翻译：超声导管探头
公开(公告)号：US5938615A
公开(公告)日：1999-08-17
申请号：US935930
申请日：1997-09-23
申请人： Michael J. Eberle , Gary P. Rizzuti , Horst F. Kiepen
发明人： Michael J. Eberle , Gary P. Rizzuti , Horst F. Kiepen
IPC分类号： A61B8/06 , A61B8/12 , A61B8/14 , B06B1/02 , B06B1/06 , G01S15/89 , G10K11/00
CPC分类号： A61B8/06 , A61B8/12 , A61B8/4483 , A61B8/4488 , A61B8/4494 , B06B1/0633 , B06B1/067 , B06B1/0674 , G01S15/892 , G01S15/8979 , G01S15/899 , G10K11/004 , G10K11/008 , A61B8/445 , B06B2201/76 , G01S15/8981 , Y10T29/42
摘要： An ultrasound catheter is disclosed for providing substantially real-time images of small cavities. The ultrasound catheter is characterized by separate and distinct materials for backing the transducers and for carrying the electronics components. The separate materials comprise an electronics carrier meeting the requirements for holding the integrated circuitry of the ultrasound device and a backing material displaying superior characteristics relating to reducing ringing and minimizing the effect of other sources of signal degradation in the transducer assembly. Also, in accordance with the present invention, a technique is described for connecting the conductor lines of the separate transducer assembly and electronics body.
摘要翻译：公开了用于提供基本上实时的小空腔图像的超声波导管。超声导管的特征在于分离和不同的材料，用于支撑换能器和携带电子部件。单独的材料包括满足用于保持超声波装置的集成电路的要求的电子载体，以及显示与减少振铃有关的优异特性并使传感器组件中的其它信号劣化的影响最小化的背衬材料。此外，根据本发明，描述了用于连接单独的换能器组件和电子体的导体线的技术。

5. 发明授权

US5135486A Self-venting balloon dilitation catheter 失效
标题翻译：自放气球扩张导管
公开(公告)号：US5135486A
公开(公告)日：1992-08-04
申请号：US575976
申请日：1990-08-31
申请人： Michael J. Eberle , Tim Cortez
发明人： Michael J. Eberle , Tim Cortez
IPC分类号： A61M29/02
CPC分类号： A61M25/104 , A61M2025/1077 , A61M2025/1079
摘要： A self-venting balloon dilatation catheter and method for producing the same having a catheter tubing including a first lumen and a second lumen. An expandable balloon is positioned at a distal end of the catheter tubing. The first lumen is for a guide wire and the second lumen is in communication with the interior of the balloon. The balloon is expanded by filling the balloon with pressurized fluid via the second lumen. An air vent within the catheter tubing purges air from the balloon when the balloon is filled with fluid. Air purged via the air vent first moves substantially transverse to a longitudinal axis of the catheter tubing and then along the longitudinal axis to an opening at a distal end of the catheter tubing. A cylindrically marker band is secured around the distal end of the catheter tuving, and another cylindrical marker band is secured around the catheter tubing inside the expandable balloon.
摘要翻译：一种自排气球囊扩张导管及其制造方法，其具有包括第一腔和第二腔的导管。可扩张气囊位于导管管的远端。第一管腔用于引导线，第二管腔与气囊的内部连通。通过经由第二管腔用加压流体填充球囊来扩张球囊。当气囊充满流体时，导管内的通风口从气囊中清除空气。通过排气口吹扫的空气首先基本上横向于导管管的纵向轴线，然后沿着纵向轴线移动到导管管的远端处的开口。圆柱形标记带固定在导管组织的远端周围，另一个圆柱形标记带固定在可扩张气囊内的导管管周围。

6. 发明授权

US6165128A Method and apparatus for making an image of a lumen or other body cavity and its surrounding tissue 有权
标题翻译：用于制造内腔或其他体腔及其周围组织的图像的方法和装置
公开(公告)号：US6165128A
公开(公告)日：2000-12-26
申请号：US166016
申请日：1998-10-05
申请人： E. I. Cespedes , C. L. de Korte , A. F. W. van der Steen
发明人： E. I. Cespedes , C. L. de Korte , A. F. W. van der Steen
IPC分类号： A61B1/00 , A61B8/08 , A61B8/12
CPC分类号： A61B5/02007 , A61B8/08 , A61B8/0858 , A61B8/12 , A61B8/485
摘要： Method and apparatus for making an image of a lumen and surrounding tissue in a body by inserting a transducer in the cavity and emitting ultrasound signals and collecting and processing echo signals to form an image, where the apparatus includes a signal processor arranged for performing the steps of and the method includes the steps of:a) obtaining echo signals from tissue at a given state of mechanical stress in a chosen direction;b) obtaining similar echo signals after a change of the mechanical stress;c) identifying the lumen-tissue boundary;d) comparing the echo signals to obtain a parameter indicative of tissue stiffness;e) performing similar steps for a number of directions;f) deriving and displaying the conventional echo image of the lumen and surrounding tissue from the echo signals of step a);g) superimposing in said image the tissue stiffness as a coded line along the lumen-tissue boundary.
摘要翻译：用于通过将换能器插入腔内并发射超声信号并收集和处理回波信号以形成图像来制造体内图像和周围组织的方法和装置，其中所述装置包括布置成执行步骤的信号处理器并且该方法包括以下步骤：a）在给定的机械应力状态下从所选方向获得来自组织的回波信号; b）在机械应力变化之后获得类似的回波信号; c）识别管腔组织边界; d）比较回波信号以获得指示组织刚度的参数; e）为多个方向执行类似的步骤; f）从步骤a）的回波信号导出和显示管腔和周围组织的常规回波图像; g）在所述图像中叠加组织刚度作为沿着管腔 - 组织边界的编码线。

7. 发明授权

US6106476A Ultra miniature pressure sensor and guide wire using the same and method 失效
标题翻译：超微型压力传感器和导丝采用相同的方法
公开(公告)号：US6106476A
公开(公告)日：2000-08-22
申请号：US912879
申请日：1997-08-15
申请人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
发明人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
IPC分类号： A61B5/0215 , A61F2/958 , A61M25/00 , A61M25/09 , G01L9/00 , A61B5/00
CPC分类号： G01L19/141 , A61B5/0215 , A61B5/6851 , A61M25/09 , G01L19/0084 , G01L19/147 , G01L19/149 , G01L9/0054 , A61M2025/0002 , A61M2025/09008 , A61M2025/09083 , A61M25/10
摘要： A guide wire having pressure sensing capabilities for measuring the pressure of liquid in a vessel comprising a flexible elongate member and having proximal and distal extremities and having an outside diameter of 0.018" or less. The distal extremity of said flexible elongate member is adapted to be disposed in the liquid in said vessel. A housing is carried by the flexible elongate member and has a diameter substantially the same as the diameter of the flexible elongate member. The housing has a space therein with a pressure sensor mounted in the space in the housing. The pressure sensor has a diaphragm that is sensitive to changes of pressure in the liquid in the vessel. The diaphragm is rectangular in shape and is bordered by a rim surrounding the well. A backing plate is formed of an insulating material bonded to the crystal and serves to reinforce the rim of the crystal of semiconductor material. The backing plate has a cavity therein underlying the diaphragm and is in substantial registration with the diaphragm. The cavity serves to provide a pressure reference.
摘要翻译：一种导丝，其具有用于测量容器中液体的压力的压力感测能力，该容器包括柔性细长构件并具有近端和远端，外径为0.018“或更小。所述柔性细长构件的远端适于设置在所述容器中的液体中。壳体由柔性细长构件承载并且具有与柔性细长构件的直径基本相同的直径。壳体具有安装在壳体的空间中的压力传感器的空间。压力传感器具有对容器中的液体中的压力变化敏感的隔膜。隔膜是矩形的形状，并且围绕着井的边缘。背板由结合到晶体上的绝缘材料形成，用于加强半导体材料晶体的边缘。背板在其下面具有腔室，并且与隔膜基本上对准。腔用于提供压力参考。

8. 发明授权

US6036650A Ultrasonic imaging system and method with ringdown reduction 有权
标题翻译：超声波成像系统和减震方法
公开(公告)号：US6036650A
公开(公告)日：2000-03-14
申请号：US153819
申请日：1998-09-15
申请人： Ching-Chen Wu , Gerald L. Litzza , David Bleam , Randall C. Ziegenbein
发明人： Ching-Chen Wu , Gerald L. Litzza , David Bleam , Randall C. Ziegenbein
IPC分类号： G01N29/44 , A61B8/12 , G01S7/52 , G01S15/89
CPC分类号： A61B8/12 , G01S7/52046 , G01S15/8922 , G01S7/5206
摘要： Ultrasonic imaging method and apparatus in which a reference waveform which is substantially free of echoes is modified to be equal to a weighted sum of the reference waveform and filtered signals from the transducing elements which transmit the ultrasonic waves and receive the reflected echoes. The modified waveform is then subtracted from the transducer signals to remove ringdown signals and provide a displayed image which is substantially free of ringdown artifacts.
摘要翻译：基本上没有回波的参考波形的超声波成像方法和装置被修改为等于来自传输超声波并且接收反射回波的传感元件的参考波形和滤波信号的加权和。然后从换能器信号中减去经修改的波形，以消除振铃信号，并提供基本上没有振铃效应的显示图像。

9. 发明授权

US5368037A Ultrasound catheter 失效
标题翻译：超声导管
公开(公告)号：US5368037A
公开(公告)日：1994-11-29
申请号：US12251
申请日：1993-02-01
申请人： Michael J. Eberle , Gary P. Rizzuti , Horst F. Kiepen
发明人： Michael J. Eberle , Gary P. Rizzuti , Horst F. Kiepen
IPC分类号： A61B8/06 , A61B8/12 , A61B8/14 , B06B1/02 , B06B1/06 , G01S15/89 , G10K11/00 , H04R17/00
CPC分类号： A61B8/12 , A61B8/06 , A61B8/445 , A61B8/4483 , A61B8/4488 , A61B8/4494 , B06B1/0633 , B06B1/067 , B06B1/0674 , G01S15/8915 , G01S15/8979 , G01S15/899 , G10K11/004 , G10K11/008 , B06B2201/76 , G01S15/892 , G01S15/8981 , Y10T29/42
摘要： An ultrasound catheter is disclosed for providing substantially real-time images of small cavities. The ultrasound catheter is characterized by separate and distinct materials for backing the transducers and for carrying the electronics components. The separate materials comprise an electronics carrier meeting the requirements for holding the integrated circuitry of the ultrasound device and a backing material displaying superior characteristics relating to reducing ringing and minimizing the effect of other sources of signal degradation in the transducer assembly. Also, in accordance with the present invention, a technique is described for connecting the conductor lines of the separate transducer assembly and electronics body.
摘要翻译：公开了用于提供基本上实时的小空腔图像的超声波导管。超声导管的特征在于分离和不同的材料，用于支撑换能器和携带电子部件。单独的材料包括满足用于保持超声波装置的集成电路的要求的电子载体，以及显示与减少振铃有关的优异特性并使传感器组件中的其它信号劣化的影响最小化的背衬材料。此外，根据本发明，描述了用于连接单独的换能器组件和电子体的导体线的技术。

10. 发明授权

US6080109A Modular imaging/treatment catheter assembly 有权
标题翻译：模块化成像/治疗导管组装
公开(公告)号：US6080109A
公开(公告)日：2000-06-27
申请号：US234967
申请日：1999-01-21
申请人： Bruce A. Baker , Clifford R. Varney , Michael J. Eberle
发明人： Bruce A. Baker , Clifford R. Varney , Michael J. Eberle
IPC分类号： A61M25/00 , A61B8/12 , A61F2/958 , A61M25/01
CPC分类号： A61M25/10 , A61B8/00 , A61B2090/3784 , A61B2090/3966 , A61B8/0891 , A61B8/12 , A61B8/4416 , A61B8/445 , Y10T29/42
摘要： Catheter assembly in which an imaging transducer is positioned proximally of a treatment device at the distal end of a catheter. Unrestricted flow between a fluid lumen in the catheter and the treatment device is provided by an annular passageway formed between the walls of a marker tube which extends through the transducer and a guide wire tube which passes through the marker tube, and by a plenum chamber which is formed between the distal end of the catheter and the proximal end of the marker tube in communication with the fluid lumen and the flow passageway. The catheter, the treatment device, and the transducer are all constructed as individual modular units which can be assembled together as desired to form the assembly.
摘要翻译：导管组件，其中成像传感器位于导管远端处的治疗装置的近侧。在导管中的流体腔和治疗装置之间的无限制流动由形成在标记管的壁之间的环形通道提供，该标记管延伸穿过换能器和穿过标记管的导丝管，以及通过室形成在导管的远端和与流体腔和流动通道连通的标记管的近端之间。导管，治疗装置和换能器都被构造为单独的模块单元，其可以根据需要组装在一起以形成组件。

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