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    • 1. 发明授权
    • Method for the detection of lateral flow assay and strip and laser-induced epifluorescence and compact scanner therefor
    • 检测横向流量测定和条带和激光诱导的落射荧光的方法和紧凑型扫描仪
    • US08011228B2
    • 2011-09-06
    • US10585467
    • 2005-01-05
    • Kie-Bong NahmEui-Yeol ChoiJae-Hoon Kim
    • Kie-Bong NahmEui-Yeol ChoiJae-Hoon Kim
    • G01N13/00
    • G01N33/558G01N21/6428G01N21/645G01N21/8483
    • Disclosed is a lateral flow quantitative assay method capable of quantitatively determining the concentration and analyzing the spatial distribution of a disease marker by employing the principle of the laser-induced fluorescence detection technique, which is based on detecting emitted fluorescence when laser light is focused to the disease marker deposited onto a lateral flow quantitative assay chip. The present invention discloses a strip, a laser-induced epifluorescence detection device and a small scanner for the assay method. The present assay method is advantageous in terms of allowing quantitative point-of-care diagnostics in hospitals, being capable of specifically detecting a disease marker by optimizing a lateral flow assay biochip for diagnosis of a specific disease, allowing more accurate quantitative analysis of analytes, and being capable of simultaneously analyzing several cancer markers, reducing the hook effect and expanding the detection range and accurately measuring concentration of analytes.
    • 公开了一种侧流定量测定方法,其能够通过采用激光诱导荧光检测技术的原理定量测定浓度并分析疾病标记物的空间分布,该方法基于当激光聚焦于 疾病标记物沉积在侧流定量测定芯片上。 本发明公开了一种用于测定方法的条带,激光诱导的落射荧光检测装置和小型扫描仪。 本测定方法在医院中允许定量点护理诊断方面是有利的,能够通过优化用于诊断特定疾病的侧流测定生物芯片来特异性检测疾病标记,从而允许对分析物进行更准确的定量分析, 并能够同时分析几种癌症标志物,减少钩效应,扩大检测范围,并准确测量分析物的浓度。
    • 10. 发明申请
    • DEVICE FOR MEASURING REFLECTIVE ABSORBANCE AND INTEGRATED DEVICE FOR MEASURING REFLECTIVE ABSORBANCE AND LATERAL FLOW ANALYSIS
    • 用于测量反射吸收和集成装置的装置,用于测量反射吸收和横向流动分析
    • US20140320862A1
    • 2014-10-30
    • US14357994
    • 2012-11-13
    • BODITECHMED. INC
    • Byeong Chul KimJae-min LeeJeong-hyeok Jeong
    • G01N21/55
    • G01N21/55B01L3/502715B01L2200/027B01L2200/0684B01L2300/0654B01L2300/0663B01L2300/0825G01N21/8483
    • The present disclosure is related to a device for measuring reflective absorbance, a device for lateral flow assay, and a device comprising the same which is able to performing both absorbance measurement and lateral flow assay together. The present device for measuring reflective absorbance comprises a base member comprising a sample receiving part; and a cover member covering an upper portion of the base member; the cover member comprising a sample inlet through which a sample is introduced into the sample receiving part and a light transmitting member. The present integrated device for measuring reflective absorbance and lateral flow assay, the integrated device comprises a cover member and a base member, the cover member and the base member extending in one direction from the corresponding parts in the device for measuring reflective absorbance, wherein the cover member formed on the lateral flow assay device comprise a second sample inlet and a window, the base member formed on the lateral flow assay device comprises a strip receiving part, which may further comprises a window cover. The present devices provides convenient loading of a sample and also provides an accurate, reliable and reproducible result for example by measuring the reflective absorbance. Also the present integrated device provides further convenience by performing a lateral flow assay and absorption measurement in one device.
    • 本公开涉及用于测量反射吸光度的装置,用于横向流动测定的装置以及包括该装置的装置,其能够一起进行吸光度测量和侧向流动测定。 用于测量反射吸光度的本装置包括:基部构件,包括样品接收部分; 以及盖构件,其覆盖所述基座构件的上部; 所述盖构件包括样品入口,样品通过所述样品入口引入所述样品接收部分和透光构件。 本发明的用于测量反射吸光度和侧向流动测定的集成装置,该集成装置包括盖构件和基底构件,盖构件和基底构件在用于测量反射吸光度的装置中的相应部分沿一个方向延伸,其中, 形成在侧流测定装置上的盖构件包括第二样品入口和窗口,形成在侧流测定装置上的基底构件包括条带接收部分,其可以进一步包括窗口盖。 本装置提供样品的方便加载,并且例如通过测量反射吸光度提供准确,可靠和可重现的结果。 此外,本集成装置通过在一个装置中执行横向流量测定和吸收测量来提供进一步的便利。