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1. 发明授权

US09592155B2 Calibrating laser beam position and shape using an image capture device 有权
标题翻译：使用图像捕获装置校准激光束的位置和形状
公开(公告)号：US09592155B2
公开(公告)日：2017-03-14
申请号：US12915401
申请日：2010-10-29
申请人： Dimitri A. Chernyak , Keith Holliday , Mathew Clopp
发明人： Dimitri A. Chernyak , Keith Holliday , Mathew Clopp
IPC分类号： A61F9/008 , B23K26/03 , G01J1/42
CPC分类号： A61F9/008 , A61B18/20 , A61F9/00802 , A61F2009/00855 , A61F2009/00872 , B23K26/032 , B23K26/0622 , B23K26/705 , G01J1/4257
摘要： The present invention provides improved methods and systems for laser beam positioning, shape profile, size profile, drift, and/or deflection calibration using an image capture device, such as a microscope camera, for enhanced calibration accuracy and precision. The methods and systems are particularly suited for iris calibration and hysteresis measurement of a variable diameter aperture. One method for calibrating laser pulses from a laser eye surgery system using an image capture device comprises imaging a known object with an image capture device. A pulsed laser beam is directed onto a calibration surface so as to leave a mark on the calibration surface. The mark on the calibration surface is then imaged with the image capture device. The laser eye surgery system is calibrated by comparing the image of the mark on the calibration surface to the image of the known object.
摘要翻译：本发明提供了使用诸如显微镜照相机的图像捕获装置的激光束定位，形状轮廓，尺寸分布，漂移和/或偏转校准的改进的方法和系统，以提高校准精度和精度。该方法和系统特别适用于可变直径孔径的虹膜校准和滞后测量。使用图像捕获装置从激光眼睛手术系统校准激光脉冲的一种方法包括用图像捕获装置成像已知物体。脉冲激光束被引导到校准表面上，以便在校准表面上留下标记。然后用图像捕获装置对校准表面上的标记进行成像。通过将校准表面上的标记的图像与已知对象的图像进行比较来校准激光眼睛手术系统。

2. 发明授权

US08968279B2 Systems and methods for qualifying and calibrating a beam delivery system 有权
标题翻译：用于排放和校准射束输送系统的系统和方法
公开(公告)号：US08968279B2
公开(公告)日：2015-03-03
申请号：US11339984
申请日：2006-01-25
申请人： Mark E. Arnoldussen
发明人： Mark E. Arnoldussen
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00817 , A61F2009/00855 , A61F2009/00872 , A61F2009/00897
摘要： Systems and methods for testing a laser eye surgery system are provided. Methods include establishing an image scale based on a calibration pattern, imageably altering a series of regions of a test surface with the laser system, laterally redirecting a laser beam to form a test pattern, imaging the test pattern, determining a lateral redirecting characteristic of the beam delivery system, and qualifying or calibrating the beam delivery system. Systems can include an input module that accepts an input member such as a calibration pattern parameter, a calibration pattern image, an intended pattern parameter, a test pattern image, an imaging device position, a calibration pattern position, a test pattern position, and a beam delivery system position, a characterization module that determines a beam delivery system characteristic, and an output module that generates a calibration for the beam delivery system of the laser eye surgery system.
摘要翻译：提供了一种用于测试激光眼睛手术系统的系统和方法。方法包括基于校准图案建立图像尺度，用激光系统成像地改变测试表面的一系列区域，横向地重定向激光束以形成测试图案，成像测试图案，确定测试图案的横向重定向特性射束输送系统，以及排放或校准射束输送系统。系统可以包括接收诸如校准图案参数，校准图案图像，预期图案参数，测试图案图像，成像设备位置，校准图案位置，测试图案位置和输入元件的输入模块的输入模块射束输送系统位置，确定射束输送系统特征的表征模块以及产生激光眼外科手术系统的束传递系统的校准的输出模块。

3. 发明授权

US08911086B2 Compound modulation transfer function for laser surgery and other optical applications 有权
标题翻译：用于激光手术和其他光学应用的复合调制传递函数
公开(公告)号：US08911086B2
公开(公告)日：2014-12-16
申请号：US13732124
申请日：2012-12-31
申请人： AMO Manufacturing USA, LLC
发明人： Guang-ming Dai
IPC分类号： A61B3/10 , A61B3/00 , A61B3/02 , G02C7/02 , A61F2/16 , A61F9/008
CPC分类号： A61B3/02 , A61B3/0016 , A61B3/0025 , A61F9/00808 , G02C7/028
摘要： Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.
摘要翻译：方法，装置和系统建立了减轻或治疗患者视力状况的光学表面形状。可以通过使用复合调制传递函数（CMTF），使用特定患者的一组患者参数来确定特定患者的光学表面形状。复合调制传递函数可以包括多个不同频率的调制传递函数（MTF）的组合。

4. 发明申请

US20120271287A1 APPLICATION OF BLEND ZONES, DEPTH REDUCTION, AND TRANSITION ZONES TO ABLATION SHAPES 审中-公开
标题翻译：混合区，深度减少和过渡区应用于排列形状
公开(公告)号：US20120271287A1
公开(公告)日：2012-10-25
申请号：US13539605
申请日：2012-07-02
申请人： Erik Gross , Rich Hofer , Jonathan Wong
发明人： Erik Gross , Rich Hofer , Jonathan Wong
IPC分类号： A61F9/01
CPC分类号： A61F9/008 , A61F9/00806 , A61F9/00808 , A61F9/00817 , A61F2009/00844 , A61F2009/00846 , A61F2009/00848 , A61F2009/00872 , A61F2009/0088
摘要： Methods, devices, and systems for reprofiling a surface of a cornea of an eye ablate a portion of the cornea to create an ablation zone with an optically correct central optical zone disposed in a central portion of the cornea, and a blend zone disposed peripherally to the central optical zone and at least partially within an optical zone of the eye. The blend zone can have an optical power that gradually diminishes with increasing radius from the central optical zone.
摘要翻译：用于重新生成眼睛角膜表面的方法，装置和系统消融角膜的一部分以产生具有设置在角膜中心部分的光学校正中心光学区的消融区，以及混合区，中心光学区域并且至少部分地在眼睛的光学区域内。混合区域可以具有随中心光学区域的半径增加而逐渐减小的光学功率。

5. 发明授权

US08182472B2 Intrastromal refractive correction systems and methods 有权
$Intrastromal refractive correction systems and methods$
公开(公告)号：US08182472B2
公开(公告)日：2012-05-22
申请号：US12471090
申请日：2009-05-22
申请人： Kingman Yee
发明人： Kingman Yee
IPC分类号： A61B18/18
CPC分类号： A61F9/00829 , A61F9/00836 , A61F9/00838 , A61F2009/00846 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882 , A61F2009/00895
摘要： Devices, systems, and methods for laser eye surgery selectively ablate tissues within the cornea of an eye along one or more target surfaces, so that corneal tissue bordered by the laser incision surface(s) can be mechanically removed. An appropriate tissue-shaping surface can be selected based on the regular refractive error of the eye, and a shape of the target laser surface(s) can be calculated so as to correct irregular refractive errors of the eye, impose desired additional sphero-cylindrical and/or irregular alterations.

6. 发明授权

US08142499B2 Presbyopia correction through negative high-order spherical aberration 有权
标题翻译：老花眼矫正通过负高阶球面像差
公开(公告)号：US08142499B2
公开(公告)日：2012-03-27
申请号：US12207444
申请日：2008-09-09
申请人： Seema Somani , Kingman Yee
发明人： Seema Somani , Kingman Yee
IPC分类号： A61F2/16
CPC分类号： A61B3/103 , A61B3/1015 , A61F2/164 , A61F9/00 , A61F9/008 , A61F9/00806 , A61F9/00808 , A61F2009/00844 , A61F2009/00872 , A61F2009/0088 , G02C7/041 , G02C7/042 , G02C2202/22
摘要： Devices, systems, and methods for treating and/or determining appropriate prescriptions for one or both eyes of a patient are particularly well-suited for addressing presbyopia, often in combination with concurrent treatments of other vision defects. High-order spherical aberration may be imposed in one or both of a patient's eyes, often as a controlled amount of negative spherical aberration extending across a pupil. A desired presbyopia-mitigating quantity of high-order spherical aberration may be defined by one or more spherical Zernike coefficients, which may be combined with Zernike coefficients generated from a wavefront aberrometer. The resulting prescription can be imposed using refractive surgical techniques such as laser eye surgery, using intraocular lenses and other implanted structures, using contact lenses, using temporary or permanent corneal reshaping techniques, and/or the like.
摘要翻译：用于治疗和/或确定患者的一只眼睛或两只眼睛的适当处方的装置，系统和方法特别适合于解决老花眼，通常与其他视力缺陷的并发治疗相结合。高次球面像差可以施加在患者眼睛的一个或两个中，通常作为延伸穿过瞳孔的受控量的负球面像差。可以通过一个或多个球形Zernike系数来定义所需的老花眼减轻量的高阶球面像差，该Zernike系数可以与从波前像差计产生的Zernike系数组合。所得到的处方可以使用屈光手术技术如激光眼科手术，使用眼内透镜和其它植入结构，使用隐形眼镜，使用临时或永久角膜重塑技术等来实施。

7. 发明授权

US08129666B2 Optical surface shape determination by mapping a lenslet array spot pattern to spatial frequency space 有权
标题翻译：通过将小透镜阵列斑点图形映射到空间频率空间来确定光学表面形状
公开(公告)号：US08129666B2
公开(公告)日：2012-03-06
申请号：US12641011
申请日：2009-12-17
申请人： Erik Gross , Charles Campbell
发明人： Erik Gross , Charles Campbell
IPC分类号： G01J1/20
CPC分类号： G01M11/0264 , A61B3/1015
摘要： Devices systems, and methods can characterize an optical surface of an object. A wavefront sensor system focuses light energy propagating from the object to form a pattern on a detector. The system maps the pattern to an array with a transform function such as a Fourier transform. The values of array correspond to characteristic locations and signals in a transform space, for example an intensity of spatial frequency signals in frequency space. The characteristic location and intensity of these signals in transform space are used to measure the optical surface. For example, a characteristic frequency of a spatial frequency intensity peak in Fourier transform space can be used to estimate the location of spots on the detector. Alternatively, the characteristics can be used to the measure sphere, cylinder and axis of a wavefront, wavefront elevation maps and point spread functions, often without locating positions of individual spots on the detector.
摘要翻译：设备系统和方法可以表征物体的光学表面。波前传感器系统聚焦从物体传播的光能以在检测器上形成图案。系统将模式映射到具有诸如傅里叶变换的变换函数的数组。阵列的值对应于变换空间中的特征位置和信号，例如频率空间中的空间频率信号的强度。这些信号在变换空间中的特征位置和强度用于测量光学表面。例如，可以使用傅里叶变换空间中的空间频率强度峰值的特征频率来估计检测器上的斑点的位置。或者，该特征可以用于测量球体，波前的圆柱体和轴线，波前高程图和点扩散函数，通常不会在检测器上定位各个点的位置。

8. 发明授权

US07931374B2 Wavefront propagation from one plane to another 有权
标题翻译：从一个平面到另一个平面的波前传播
公开(公告)号：US07931374B2
公开(公告)日：2011-04-26
申请号：US12421246
申请日：2009-04-09
申请人： Guangming Dai , Charles E. Campbell , Li Chen , Huawei Zhao , Dimitri Chernyak
发明人： Guangming Dai , Charles E. Campbell , Li Chen , Huawei Zhao , Dimitri Chernyak
IPC分类号： A61B3/00 , A61B3/10
CPC分类号： A61B3/0025 , A61B3/1015
摘要： The present invention provides methods, systems and software for scaling optical aberration measurements of optical systems. In one embodiment, the present invention provides a method of reconstructing optical tissues of an eye. The method comprises transmitting an image through the optical tissues of the eye. Aberration data from the transmitted image is measured across the optical tissues of the eye at a first plane. A conversion algorithm is applied to the data, converting it to corrective optical power data that can be used as a basis for constructing a treatment for the eye at a second plane.
摘要翻译：本发明提供了用于缩放光学系统的光学像差测量的方法，系统和软件。在一个实施例中，本发明提供了重建眼睛的光学组织的方法。该方法包括通过眼睛的光学组织传输图像。在第一平面上跨越眼睛的光学组织测量来自透射图像的畸变数据。将转换算法应用于数据，将其转换为校正光功率数据，该光功率数据可用作在第二平面上为眼睛构建治疗的基础。

9. 发明授权

US07836893B2 Method for stabilizing delivered laser energy 有权
标题翻译：稳定传递激光能量的方法
公开(公告)号：US07836893B2
公开(公告)日：2010-11-23
申请号：US11077173
申请日：2005-03-09
申请人： Keith Holliday
发明人： Keith Holliday
IPC分类号： A61B19/00 , A61B18/20
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00819 , A61F2009/00848 , A61F2009/00855 , A61F2009/00872
摘要： Systems and methods provide for stabilizing the amount of laser energy delivered to a target from a laser device. Generally, delivered laser energy is measured over multiple laser pulses or over time in the case of a constant wave laser. A decrease is then calculated in the delivered energy, the decrease being caused by accumulation of one or more substances, such as ozone, along the laser beam delivery path due to passage of the laser beam along the path. Using this calculated decrease, a laser device may be adjusted to compensate for the decrease in delivered energy due to the accumulated substance(s), thus stabilizing the amount of energy delivered to the target.
摘要翻译：系统和方法提供了稳定从激光装置传送到目标物体的激光能量的量。通常，在恒定波激光器的情况下，通过多个激光脉冲或随时间测量传送的激光能量。然后在输送的能量中计算减小，该减少是由于激光束沿着路径的通过沿着激光束输送路径的一个或多个物质（例如臭氧）的积聚而引起的。使用该计算的减少，可以调整激光装置以补偿由于所累积的物质导致的递送能量的减少，从而稳定传递到目标的能量的量。

10. 发明申请

US20100234833A1 TRANSFORMATION METHODS OF WAVEFRONT MAPS FROM ONE VERTEX DISTANCE TO ANOTHER 有权
标题翻译： WAVEFRONT MAPS从一个VERTEX距离到另一个的转换方法
公开(公告)号：US20100234833A1
公开(公告)日：2010-09-16
申请号：US12786756
申请日：2010-05-25
申请人： Guangming Dai
发明人： Guangming Dai
IPC分类号： A61F9/008 , A61B3/10 , A61B18/20
CPC分类号： A61F9/00806 , A61F9/00817 , A61F2009/00844 , A61F2009/00848 , A61F2009/00872 , A61F2009/0088
摘要： The present invention provides methods, systems and software for scaling optical aberration measurements of optical systems. In one embodiment, the present invention provides a method of reconstructing optical tissues of an eye. The method comprises transmitting an image through the optical tissues of the eye. Aberration data from the transmitted image is measured across the optical tissues of the eye at a first plane. A conversion algorithm is applied to the data, converting it to corrective optical power data that can be used as a basis for constructing a treatment for the eye at a second plane.
摘要翻译：本发明提供了用于缩放光学系统的光学像差测量的方法，系统和软件。在一个实施例中，本发明提供了重建眼睛的光学组织的方法。该方法包括通过眼睛的光学组织传输图像。在第一平面上跨越眼睛的光学组织测量来自透射图像的畸变数据。将转换算法应用于数据，将其转换为校正光功率数据，该光功率数据可用作在第二平面上为眼睛构建治疗的基础。

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