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1. 发明授权

US09173852B2 Glycyrrhetinic acid-mediated nanoparticles of hepatic targeted drug delivery system, process for preparing the same and use thereof 有权
标题翻译：甘草次酸介导的肝靶向药物递送系统的纳米颗粒，其制备方法及其用途
公开(公告)号：US09173852B2
公开(公告)日：2015-11-03
申请号：US12338966
申请日：2008-12-18
申请人： Zhi Yuan , Wei Huang , Qin Tian , Chuangnian Zhang , Liang Han , Tong Liu , Yue Zhang , Yue Chen
发明人： Zhi Yuan , Wei Huang , Qin Tian , Chuangnian Zhang , Liang Han , Tong Liu , Yue Zhang , Yue Chen
IPC分类号： A61K9/51 , A61K47/36 , A61K47/48
CPC分类号： A61K9/5146 , A61K9/5161 , A61K9/5192 , A61K47/593 , A61K47/60 , A61K47/61 , A61K47/645 , A61K47/6935 , Y10S977/773 , Y10S977/906
摘要： Disclosed are a hepatic targeted drug delivery system and a process for preparing the same. Also disclosed is a method for treating liver cancer.
摘要翻译：公开了肝靶向药物递送系统及其制备方法。还公开了一种治疗肝癌的方法。

2. 发明申请

US20060006659A1 Multiple backset latch 有权
标题翻译：多重复位锁定
公开(公告)号：US20060006659A1
公开(公告)日：2006-01-12
申请号：US11038993
申请日：2005-01-20
申请人： Zhi Yuan
发明人： Zhi Yuan
IPC分类号： E05C1/00
CPC分类号： E05B63/06 , E05B55/005 , Y10S292/60 , Y10T292/06
摘要： Disclosed is a door latch assembly having an integrated means to accommodate multiple backset dimension requirements while facilitating the backset adjustment selection to be done in an easy and convenient manner. The multiple backset latch has as primary components a housing body assembly and a latch bolt housing assembly. The latch bolt housing assembly includes a housing body channel member, a cam support plate member, a bolt retractor member, a cam lever member, a positioning spring member, and a housing body plate. The latch bolt housing assembly further includes a latch bolt head. The housing body channel has an oval aperture corresponding to accept the cam lever member. The oval aperture has multiple radii sufficient to accommodate lateral movement to provide 60 mm (2⅜ inches) and 70 mm (2¾ inches) backset.
摘要翻译：公开了一种门锁组件，其具有集成的装置，以适应多个回缩尺寸要求，同时便于以容易且方便的方式进行背板调节选择。该多重回缩闩锁具有壳体主体组件和闩锁螺栓壳体组件作为主要部件。闩锁螺栓壳体组件包括壳体通道构件，凸轮支撑板构件，螺栓牵开构件，凸轮杆构件，定位弹簧构件和壳体主体板。闩锁螺栓壳体组件还包括闩锁螺栓头。壳体通道具有对应于接受凸轮杆构件的椭圆形孔。椭圆形孔径具有足够的半径以适应横向运动，以提供60毫米（23/8英寸）和70毫米（2¾英寸）的回波。

3. 发明授权

US08466298B2 High selectively polymeric adsorbent based on the hydrogen bonding interaction and the use thereof in isolation and purification of active components from gingko biloba extract 失效
标题翻译：基于氢键相互作用的高选择性聚合吸附剂及其在从银杏提取物中分离和纯化活性组分的用途
公开(公告)号：US08466298B2
公开(公告)日：2013-06-18
申请号：US13119371
申请日：2009-02-12
申请人： Zhi Yuan , Chunhong Wang , Rongfu Shi , Jing Zhang , Ping Ren , Yingchao Chen
发明人： Zhi Yuan , Chunhong Wang , Rongfu Shi , Jing Zhang , Ping Ren , Yingchao Chen
IPC分类号： C07D309/30 , C08F8/32
CPC分类号： A61K36/16 , B01J20/26 , B01J20/261 , B01J20/265 , B01J20/267 , B01J20/321 , B01J20/3251 , C08F8/10 , C08F8/32 , C08F220/14 , Y10T428/2982 , C08F212/36
摘要： Provided are a kind of high selectivity polymeric adsorbents with amide functional groups based on the hydrogen bonding interaction, which is prepared by adequately swelling a DVB-co-MA copolymer of 6% crosslinking degree as the initial resin with dimethyl formamide, performing an amination reaction by adding a diamine, soaking the dried resultant yellow resin with an acylating agent that is a dianhydride, and performing an acylation reaction to obtain the polymeric adsorbent with amide functional groups of the invention. The polymeric adsorbent of the invention can be used to effectively isolate and purify the active ingredients, i.e., flavones and lactones, from the extract of ginkgo leaf.
摘要翻译：提供了一种基于氢键相互作用的具有酰胺官能团的高选择性聚合物吸附剂，其通过充分溶胀具有6％交联度的DVB-co-MA共聚物作为初始树脂与二甲基甲酰胺进行胺化反应通过加入二胺，用干燥的所得黄色树脂与二酐的酰化剂浸泡，并进行酰化反应以获得具有本发明的酰胺官能团的聚合物吸附剂。本发明的聚合物吸附剂可用于从银杏提取物中有效分离和纯化活性成分，即黄酮和内酯。

4. 发明申请

US20110218346A1 High Selectivity Hydrogen Bonding Polymeric Adsorbent and its Application on the Separation and Purification of Effective Constituents from Ginkgo Extract 失效
标题翻译：高选择性氢键聚合吸附剂及其在银杏提取物分离纯化有效成分中的应用
公开(公告)号：US20110218346A1
公开(公告)日：2011-09-08
申请号：US13119371
申请日：2009-02-12
申请人： Zhi Yuan , Chunhong Wang , Rongfu Shi , Jing Zhang , Ping Ren , Yingchao Chen
发明人： Zhi Yuan , Chunhong Wang , Rongfu Shi , Jing Zhang , Ping Ren , Yingchao Chen
IPC分类号： C07D309/30 , C08F8/32 , C08J9/00
CPC分类号： A61K36/16 , B01J20/26 , B01J20/261 , B01J20/265 , B01J20/267 , B01J20/321 , B01J20/3251 , C08F8/10 , C08F8/32 , C08F220/14 , Y10T428/2982 , C08F212/36
摘要： Provided are a kind of high selectivity polymeric adsorbents with amide functional groups based on the hydrogen bonding interaction, which is prepared by adequately swelling a DVB-co-MA copolymer of 6% crosslinking degree as the initial resin with dimethyl formamide, performing an amination reaction by adding a diamine, soaking the dried resultant yellow resin with an acylating agent that is a dianhydride, and performing an acylation reaction to obtain the polymeric adsorbent with amide functional groups of the invention. The polymeric adsorbent of the invention can be used to effectively isolate and purify the active ingredients, i.e., flavones and lactones, from the extract of ginkgo leaf.
摘要翻译：提供了一种基于氢键相互作用的具有酰胺官能团的高选择性聚合物吸附剂，其通过充分溶胀6％交联度的DVB-co-MA共聚物作为起始树脂与二甲基甲酰胺进行胺化反应通过加入二胺，用干燥的所得黄色树脂与二酐的酰化剂浸泡，并进行酰化反应以获得具有本发明的酰胺官能团的聚合物吸附剂。本发明的聚合物吸附剂可用于从银杏提取物中有效分离和纯化活性成分，即黄酮和内酯。

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