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1. 发明申请

US20110166200A1 METHODS OF USING MIR210 AS A BIOMARKER FOR HYPOXIA AND AS A THERAPEUTIC AGENT FOR TREATING CANCER 审中-公开
标题翻译：使用MIR210作为生物标记物用于HYPOXIA的方法和作为治疗癌症的治疗剂
公开(公告)号：US20110166200A1
公开(公告)日：2011-07-07
申请号：US12989198
申请日：2009-04-16
申请人： Zhan Zhang , Sun Hong , Hongyue Dai , Jan Schelter , Julia Burchard , Xudong Dai , Michael Carleton , Michael Cleary , Peter Linsley , Carla Grandori
发明人： Zhan Zhang , Sun Hong , Hongyue Dai , Jan Schelter , Julia Burchard , Xudong Dai , Michael Carleton , Michael Cleary , Peter Linsley , Carla Grandori
IPC分类号： A61K31/713 , C12Q1/68 , C12N5/09 , A61P35/00
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/178
摘要： The present invention provides compositions and methods for predicting the hypoxia response in tumor cells, methods for predicting the likelihood of cancer metastasis, and methods for inhibiting tumor cell proliferation using a microRNA comprising miR-210.
摘要翻译：本发明提供用于预测肿瘤细胞中的缺氧反应的组合物和方法，用于预测癌症转移的可能性的方法，以及使用包含miR-210的微小RNA抑制肿瘤细胞增殖的方法。

2. 发明申请

US20100279119A1 METHOD FOR IMPROVING THE LONG TERM STABILITY OF NANO-CRYSTALLINE SEMICONDUCTORS 审中-公开
标题翻译：改善纳米晶体半导体长期稳定性的方法
公开(公告)号：US20100279119A1
公开(公告)日：2010-11-04
申请号：US12747627
申请日：2008-12-12
申请人： Michael Cleary , Marcello Vitale
发明人： Michael Cleary , Marcello Vitale
IPC分类号： B32B27/04 , B05D5/06
CPC分类号： C09K11/02 , C09K11/08 , Y10T428/2998
摘要： A medium is provided in which nano-crystalline semiconductors or quantum dots are stable for extended periods when subjected to exterior lighting. The colour emission of the resultant quantum dots provides a fingerprint which is still effective after one year of exposure to exterior conditions. Such encapsulation protects the quantum dots in exterior conditions, so that they may be used as pigments or coding systems based on their optical emission.
摘要翻译：提供了一种介质，其中纳米晶体半导体或量子点在经受外部照明时可长时间稳定。所得到的量子点的颜色发射提供指纹，其在暴露于外部条件一年后仍然有效。这种封装在外部条件下保护量子点，使得它们可以用作基于其光发射的颜料或编码系统。

3. 发明授权

US5811152A Method of identifying a surface 失效
标题翻译：识别表面的方法
公开(公告)号：US5811152A
公开(公告)日：1998-09-22
申请号：US762834
申请日：1996-12-10
申请人： Michael Cleary
发明人： Michael Cleary
IPC分类号： G09F3/00 , G08B15/00 , G08B15/02
CPC分类号： G09F3/00
摘要： A method for identifying a surface in which a plurality of trace material is used to establish a database in which a unique combination of trace materials is assigned to a unique source. A composition is formulated containing the unique combination together with an indicator material and a solvent system, the solvent system including a solvent which is volatile under conditions of application. This composition is applied to a surface and the solvent permitted to evaporate, after which the composition is detected on the basis of the indicator material and each of the plurality of trace materials is identified. The unique source can then be determined from the database.
摘要翻译：用于识别表面的方法，其中使用多个迹线材料来建立数据库，其中将唯一的迹线材料组合分配给唯一的源。将组合物与指示剂材料和溶剂体系一起配制成独特的组合物，溶剂体系包括在施用条件下挥发的溶剂。将该组合物施用于表面，允许溶剂蒸发，之后基于指示剂材料检测组合物，并鉴定出多种痕量物质。然后可以从数据库确定唯一的来源。

4. 发明申请

US20140008581A1 MARKER SYSTEM 有权
标题翻译：标记系统
公开(公告)号：US20140008581A1
公开(公告)日：2014-01-09
申请号：US13639096
申请日：2012-03-30
申请人： Michael Cleary
发明人： Michael Cleary
IPC分类号： C09D7/12
CPC分类号： C09J133/08 , B32B37/1284 , B32B37/18 , B32B38/0036 , B32B2519/00 , C08K3/40 , C09D5/18 , C09D7/61 , Y10T156/10 , Y10T436/13
摘要： A marker system for applying to surfaces of items, articles, goods, vehicles and/or premises, said marker system comprising: a marker comprising a temperature resilient medium having a predefined carbonisation temperature capable of securing the marker system onto a surface; wherein the medium contains an inorganic matrix having a predefined fusing point lower than the predefined carbonisation temperature of the medium; such that when the marker system is subjected to temperatures above the predefined carbonisation temperature of the medium, the inorganic matrix fuses to the marker to form an adhesive protective layer thereby securing the marker onto said surface. A composition comprising the marker system. An item, an article, a good, a vehicle and/or premises comprising a surface impregnated with the marker system.
摘要翻译：一种用于应用于物品，物品，货物，车辆和/或处所的表面的标记系统，所述标记系统包括：标记，其包括温度弹性介质，其具有能够将标记系统固定在表面上的预定碳化温度; 其中所述介质包含具有低于介质的预定碳化温度的预定熔点的无机基质; 使得当标记系统经受高于介质的预定碳化温度的温度时，无机基质熔合到标记以形成粘合保护层，从而将标记固定到所述表面上。包含标记系统的组合物。一种物品，物品，物品，车辆和/或房屋，其包括用标记系统浸渍的表面。

5. 发明授权

US08579188B2 Methods of in-field analysis 有权
标题翻译：现场分析方法
公开(公告)号：US08579188B2
公开(公告)日：2013-11-12
申请号：US13610334
申请日：2012-09-11
申请人： Michael Cleary , Marcello Vitale
发明人： Michael Cleary , Marcello Vitale
IPC分类号： G06F17/00
CPC分类号： G07D7/205 , G01N21/25 , G01N21/65 , G01N2021/6439 , G07D7/12 , G07D7/2033
摘要： The present invention relates to the use of unique markers in the identification and tracking of objects. The present invention provides large numbers of unique markings for application to items as part of a marking system. The present invention provides a new approach to laboratory analysis and a means of rapid in-field identification of goods using a hand-held scanner. It provides data that can be used as a means of product tracking, identification of counterfeit product and to prove ownership of stolen goods.
摘要翻译：本发明涉及在识别和跟踪对象中使用独特标记。本发明提供大量用于作为标记系统的一部分的项目的独特标记。本发明提供了一种新的实验室分析方法以及使用手持式扫描仪快速现场识别货物的手段。它提供的数据可以用作产品跟踪的手段，识别假冒产品，并证明赃物的所有权。

6. 发明授权

US07094305B2 Method for particle production 失效
标题翻译：颗粒生产方法
公开(公告)号：US07094305B2
公开(公告)日：2006-08-22
申请号：US11059952
申请日：2005-02-17
申请人： Michael Cleary
发明人： Michael Cleary
IPC分类号： G03C5/00 , G09F3/02 , B23K26/02
CPC分类号： B29B9/04 , B29B9/12 , B29B2009/125 , Y10T156/1064 , Y10T156/1075 , Y10T156/1082 , Y10T156/1085
摘要： A method of producing batches of micro particles includes affixing a substrate sheet to a support and cutting the substrate sheet with a laser device to define a plurality of micro particles. Before, after or during the cutting of the substrate sheet, the region of the substrate sheet defining each micro particle is marked with a code or other identifying marking using a laser device. The code or other identifying marking is unique to the particular batch of micro particles to uniquely identify that batch. The micro particles are removed from the support by a solvent. Preferably, a single laser device is used for cutting the substrate sheet and marking the micro particles. Alternatively, separate laser devices may be used for cutting the substrate sheet and marking the micro particles.
摘要翻译：生产批次的微粒子的方法包括将基片固定在支撑体上，用激光装置切割基片以限定多个微粒。在切割基片之前，之后或期间，限定每个微粒的基片的区域用代码或使用激光装置的识别标记标记。代码或其他识别标记对于特定批次的微粒子是唯一的，以唯一地标识该批次。通过溶剂将微粒从载体上除去。优选地，单个激光装置用于切割基片并标记微粒。或者，单独的激光装置可用于切割基片并标记微粒。

7. 发明申请

US20050140063A1 Method for particle production 失效
标题翻译：颗粒生产方法
公开(公告)号：US20050140063A1
公开(公告)日：2005-06-30
申请号：US11059952
申请日：2005-02-17
申请人： Michael Cleary
发明人： Michael Cleary
IPC分类号： B29B9/04 , B29B9/12 , B29C35/08
CPC分类号： B29B9/04 , B29B9/12 , B29B2009/125 , Y10T156/1064 , Y10T156/1075 , Y10T156/1082 , Y10T156/1085
摘要： A method of producing batches of micro particles, comprises: e) affixing a substrate sheet to a support f) cutting the substrate sheet by means of a laser device to define a plurality of micro particles; g) either before, after or during the cutting the substrate sheet, marking the region of the substrate sheet defining each micro particle by means of a laser device with a code or other identifying marking, said code or other identifying marking being unique to that particular batch of micro particles to uniquely identify that batch; and h) removing the micro particles from the support by means of a solvent. Preferably a single laser device is used for cutting the substrate sheet and marking the micro particles. Alternatively, separate laser devices may be used for respectively cutting the substrate sheet and marking the micro particles.
摘要翻译：一种生产批次的微粒的方法，包括：e）将基材片固定在载体上; f）借助于激光装置切割基片以限定多个微粒; g）在切割基材片材之前，之后或之中，通过具有代码或其他识别标记的激光装置标记限定每个微粒子的基片的区域，所述代码或其他识别标记对于该特定的批次的微粒唯一识别该批次; 和h）通过溶剂从载体中除去微粒子。优选地，单个激光装置用于切割基片并标记微粒。或者，单独的激光装置可以用于分别切割基片并标记微粒。

8. 发明申请

US20050065877A1 Method and system for distribution of unactivated bank account cards 有权
标题翻译：未激活的银行账户卡的分配方法和系统
公开(公告)号：US20050065877A1
公开(公告)日：2005-03-24
申请号：US10667353
申请日：2003-09-23
申请人： Michael Cleary , David Clifton , Dean Ilijasic , David Cohen , Kristine Rodgers
发明人： Michael Cleary , David Clifton , Dean Ilijasic , David Cohen , Kristine Rodgers
IPC分类号： G06F17/60
CPC分类号： G06Q20/354 , G06Q20/10 , G06Q20/1085 , G06Q40/00 , G06Q40/02 , G06Q40/025
摘要： The invention comprises a method for distributing dead bank cards to customers who have not solicited a bank card or submitted an application. The dead bank card is a bank card (e.g., ATM card, debit card, check card, and the like) which contains all necessary information to be used, including a pre-assigned bank account number, and which only requires activation/approval by the prospective new bank account customer. In one embodiment, the dead bank card is distributed in connection with live credit cards issued to applicants for credit card accounts. Once operative, the bank card and the credit card may be linked together through a rebate/rewards program.
摘要翻译：本发明包括向未向银行卡申请或提交申请的客户分发死亡银行卡的方法。死亡银行卡是一张银行卡（例如，ATM卡，借记卡，支票卡等），其中包含所有必要的信息，包括预先分配的银行帐号，仅需要激活/批准预期的新银行账户客户。在一个实施例中，死亡银行卡是与发行给信用卡账户申请人的实时信用卡一起分发的。一旦操作，银行卡和信用卡可以通过回扣/奖励计划链接在一起。

9. 发明授权

US08239323B2 Method and system for distribution of unactivated bank account cards 有权
标题翻译：未激活的银行账户卡的分配方法和系统
公开(公告)号：US08239323B2
公开(公告)日：2012-08-07
申请号：US10667353
申请日：2003-09-23
申请人： Michael Cleary , David Clifton , Dean Ilijasic , David Cohen , Kristine Rodgers
发明人： Michael Cleary , David Clifton , Dean Ilijasic , David Cohen , Kristine Rodgers
IPC分类号： G06Q40/00
CPC分类号： G06Q20/354 , G06Q20/10 , G06Q20/1085 , G06Q40/00 , G06Q40/02 , G06Q40/025
摘要： The invention comprises a method for distributing dead bank cards to customers who have not solicited a bank card or submitted an application. The dead bank card is a bank card (e.g., ATM card, debit card, check card, and the like) which contains all necessary information to be used, including a pre-assigned bank account number, and which only requires activation/approval by the prospective new bank account customer. In one embodiment, the dead bank card is distributed in connection with live credit cards issued to applicants for credit card accounts. Once operative, the bank card and the credit card may be linked together through a rebate/rewards program.
摘要翻译：本发明包括向未向银行卡申请或提交申请的客户分发死亡银行卡的方法。死亡银行卡是一张银行卡（例如，ATM卡，借记卡，支票卡等），其中包含所有必要的信息，包括预先分配的银行帐号，仅需要激活/批准预期的新银行账户客户。在一个实施例中，死亡银行卡是与发行给信用卡账户申请人的实时信用卡一起分发的。一旦操作，银行卡和信用卡可以通过回扣/奖励计划链接在一起。

10. 发明授权

US08852947B2 Application of unique surface coatings to high volume manufacturing output 有权
标题翻译：独特的表面涂层在大批量生产中的应用
公开(公告)号：US08852947B2
公开(公告)日：2014-10-07
申请号：US13146850
申请日：2010-02-02
申请人： Michael Cleary , Marcello Vitale , Sharon Robinson
发明人： Michael Cleary , Marcello Vitale , Sharon Robinson
IPC分类号： G01N37/00 , G09C3/00 , G03C11/00 , G06K19/06 , G03C5/00 , G03C3/00 , B41M3/14 , B44F1/12
CPC分类号： C09D5/22 , C09D5/00 , G03C11/00 , G06K19/06009 , Y10T436/13
摘要： A photographic material for image display including an intimately sorbed contrast agent that provides a contrast layer against which the recorded image can be seen regardless of the nature and color of the background.
摘要翻译：用于图像显示的照相材料，包括紧密吸附的造影剂，其提供对比度层，无论背景的性质和颜色如何，可以看到所记录的图像。

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