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1. 发明申请

US20100239493A1 METHODS AND COMPOUNDS FOR FORMING MONOLITHIC TITANIA, OPTIONALLY BIOMOLECULE DOPED, WITH CONTROLLED MORPHOLOGY USING BIOCOMPATIBLE SOL-GEL PROCESSES 审中-公开
标题翻译：用生物易溶性凝胶法制备单晶钛铁矿，选择性生物分子，控制形态的方法和化合物
公开(公告)号：US20100239493A1
公开(公告)日：2010-09-23
申请号：US12442434
申请日：2007-09-24
申请人： Yunyu Yi , Michael A. Brook , John D. Brennan , Yang Chen
发明人： Yunyu Yi , Michael A. Brook , John D. Brennan , Yang Chen
IPC分类号： C01G23/047 , C07F7/28 , C07H23/00
CPC分类号： B01J20/0211 , B01J20/06 , B01J20/282 , B82Y30/00 , C01G23/047 , C01G23/053 , C01P2002/52 , C01P2002/72 , C01P2002/88 , C01P2004/03 , C01P2004/04 , C01P2004/62 , C01P2004/64 , C01P2006/12 , C01P2006/62 , C01P2006/64 , C01P2006/82 , C07F7/003 , C12N9/104 , C12N11/14 , C12Y203/02002
摘要： The present invention includes polyol modified titanium compounds, their preparation and use in methods to make biomolecule compatible monolithic titania. The invention also includes the use of the biomolecule compatible monolithic titania in bioanalytic applications, for example in biosensors, chromatographic columns, microarrays and bioaffinity columns.
摘要翻译：本发明包括多元醇改性的钛化合物，它们的制备和用于制备生物分子相容的整体式二氧化钛的方法。本发明还包括在生物分析应用中使用生物分子相容的整体二氧化钛，例如在生物传感器，色谱柱，微阵列和生物亲和柱中。

2. 发明授权

US07375168B2 Protein compatible methods and compounds for controlling the morphology and shrinkage of silica derived from polyol-modified silanes 有权
标题翻译：用于控制衍生自多元醇改性硅烷的二氧化硅的形态和收缩的蛋白质相容方法和化合物
公开(公告)号：US07375168B2
公开(公告)日：2008-05-20
申请号：US10814123
申请日：2004-04-01
申请人： Zheng Zhang , Yang Chen , Jorge Cruz-Aguado , Richard J. Hodgson , Dina Tleugabulova , John D. Brennan , Michael A. Brook
发明人： Zheng Zhang , Yang Chen , Jorge Cruz-Aguado , Richard J. Hodgson , Dina Tleugabulova , John D. Brennan , Michael A. Brook
IPC分类号： C08L83/02
CPC分类号： B01J20/28085 , A61K47/52 , B01D15/3804 , B01J20/103 , B01J20/28014 , B01J20/28042 , B01J20/28083 , B01J20/28092 , B01J20/283 , B01J20/286 , B01J2220/82 , C01B33/12 , C01B33/16 , C04B35/14 , C04B35/624 , C04B35/62605 , C04B35/62655 , C04B35/632 , C04B35/634 , C04B38/0045 , C04B2235/441 , C04B2235/77 , G01N15/088 , G01N2030/528 , C04B38/0064
摘要： Siliceous materials were prepared by adding one or more additives, including one or more water soluble polymers, and derivatives thereof, as well as trifunctional silanes, to sols containing tetraalkoxysilanes derived from polyols. The polymers facilitate phase separation of the growing silica gel matrix, leading to high surface area self-supporting silica gels with cure occurring at ambient temperatures. The materials also show a significant reduction in shrinkage properties and significant protein stabilization abilities.
摘要翻译：通过向包含衍生自多元醇的四烷氧基硅烷的溶胶中加入一种或多种添加剂，包括一种或多种水溶性聚合物及其衍生物以及三官能硅烷来制备硅质材料。聚合物促进生长硅胶基质的相分离，导致高表面积自支撑硅胶，其固化在环境温度下发生。这些材料还显示收缩性能和显着的蛋白质稳定化能力的显着降低。

3. 发明授权

US08648211B2 Surface-modifying silicone elastomers 有权
标题翻译：表面改性硅氧烷弹性体
公开(公告)号：US08648211B2
公开(公告)日：2014-02-11
申请号：US13392568
申请日：2010-08-27
申请人： Michael A. Brook , Yongxin Wang , Yang Chen
发明人： Michael A. Brook , Yongxin Wang , Yang Chen
IPC分类号： C08G77/38 , C07F7/00
CPC分类号： C08J7/12 , C07F7/0838 , C08G77/045 , C08G77/12 , C08G77/20 , C08G77/46 , C09D183/12
摘要： The present disclosure describes compounds of Formula (I) wherein m is 1 to 6, n is 6 to 10 and R1 is a straight or branch chain siloxane, their use in methods to modify the surface of hydrophobic substrates to render the substrates superhydrophilic and surface-modified substrates.
摘要翻译：本公开内容描述了式（I）的化合物，其中m为1至6，n为6至10，并且R 1为直链或支链硅氧烷，它们用于改性疏水性底物表面以使底物超亲水性和表面改性基质。

4. 发明授权

US10135359B2 Hybrid full bridge-voltage doubler rectifier and single stage LLC converter thereof 有权
公开(公告)号：US10135359B2
公开(公告)日：2018-11-20
申请号：US15962102
申请日：2018-04-25
申请人： Yang Chen , Hongliang Wang , Yan-Fei Liu , Zhanming Li , Yue Fu
发明人： Yang Chen , Hongliang Wang , Yan-Fei Liu , Zhanming Li , Yue Fu
IPC分类号： H02M7/219 , H02M7/25 , H02M7/217 , H02M1/42 , H02M3/335
摘要： A hybrid rectifier that works as either a hybrid full bridge or a voltage doubler. Under 220 V AC input condition, the hybrid rectifier operates in full bridge mode, while at 110 V AC input, it operates as voltage doubler rectifier. The hybrid rectifier may be used with a DC-DC converter, such as an LLC resonant converter, in a power supply. With this mode switching, the LLC converter resonant tank design only takes consideration of 220 V AC input case, such that the required operational input voltage range is reduced, and the efficiency of the LLC converter is optimized. Both the size and power loss are reduced by using a single stage structure instead of the conventional two-stage configuration.

5. 发明授权

US08874584B1 Hierarchical video search and recognition system 有权
标题翻译：分层视频搜索和识别系统
公开(公告)号：US08874584B1
公开(公告)日：2014-10-28
申请号：US12660320
申请日：2010-02-24
申请人： Yang Chen , Swarup Medasani , David L. Allen , Qin Jiang , Yuri Owechko , Tsai-Ching Lu
发明人： Yang Chen , Swarup Medasani , David L. Allen , Qin Jiang , Yuri Owechko , Tsai-Ching Lu
IPC分类号： G06F17/30
CPC分类号： G06F17/30805 , G06F17/30811
摘要： Described is a system for content recognition, search, and retrieval in visual data. The system is configured to perform operations of receiving visual data as an input, processing the visual data, and extracting distinct activity-agnostic content descriptors from the visual data at each level of a hierarchical content descriptor module. The resulting content descriptors are then indexed with a hierarchical content indexing module, wherein each level of the content indexing module comprises a distinct set of indexed content descriptors. The visual data, generated content descriptors, and indexed content descriptors are then stored in a storage module. Finally, based on a content-based query by a user, the storage module is searched, and visual data containing the content of interest is retrieved and presented to the user. A method and computer program product for content recognition, search, and retrieval in visual data are also described.
摘要翻译：描述了用于视觉数据中的内容识别，搜索和检索的系统。该系统被配置为执行接收视觉数据作为输入，处理可视数据以及从分层内容描述符模块的每个级别的视觉数据中提取不同的活动不可知内容描述符的操作。所得到的内容描述符然后用分层内容索引模块进行索引，其中内容索引模块的每个级别包括不同的索引内容描述符集合。然后将可视数据，生成的内容描述符和索引的内容描述符存储在存储模块中。最后，基于用户的基于内容的查询，搜索存储模块，并且检索包含感兴趣内容的视觉数据并呈现给用户。还描述了用于视觉数据中的内容识别，搜索和检索的方法和计算机程序产品。

6. 发明申请

US20140147492A1 METHODS AND COMPOSITIONS FOR ENHANCING THE UPTAKE OF THERAPEUTIC AGENTS BY TARGET CELLS 有权
标题翻译：用于增强目标细胞对治疗药物摄取的方法和组合物
公开(公告)号：US20140147492A1
公开(公告)日：2014-05-29
申请号：US14008428
申请日：2012-03-28
申请人： Yongzhang Luo , Yang Chen , Yan Fu , Lin Jia , Guodong Chang
发明人： Yongzhang Luo , Yang Chen , Yan Fu , Lin Jia , Guodong Chang
IPC分类号： A61K31/7048 , A61K47/48 , A61K31/365 , A61K38/17 , A61K31/724
CPC分类号： A61K31/7048 , A61K9/0019 , A61K9/127 , A61K31/065 , A61K31/718 , A61K38/1709 , A61K38/39 , A61K39/395 , A61K45/06 , A61K47/60 , A61K2300/00
摘要： The present invention relates to a new use of a known medicament. Specifically, the invention relates to methods and compositions for enhancing the therapeutic efficacy of a therapeutic agent by increasing the uptake of the therapeutic agent by target cells, and in particular relates to a pharmaceutical composition comprising a regulating agent of lipid raft/caveolae-dependent endocytic pathway and some therapeutic agents, such as anti-tumor agents. The invention also relates to a method for screening a regulating agent of lipid raft/caveolae-dependent endocytic pathway capable of enhancing the therapeutic efficacy of anti-tumor agents.
摘要翻译：本发明涉及已知药物的新用途。具体地，本发明涉及通过增加靶细胞对治疗剂的吸收来增强治疗剂的治疗功效的方法和组合物，并且特别涉及包含脂质筏/穴ol依赖性内吞调节剂的药物组合物途径和一些治疗剂，例如抗肿瘤剂。本发明还涉及一种能够增强抗肿瘤剂治疗功效的脂筏/穴ol石依赖性内吞途径调节剂的方法。

7. 发明授权

US08590700B2 Sleeved to press-open type storage device with a prestressed to open closure 有权
公开(公告)号：US08590700B2
公开(公告)日：2013-11-26
申请号：US12081511
申请日：2008-04-17
申请人： Tai-Her Yang , Yang Chen
发明人： Tai-Her Yang , Yang Chen
IPC分类号： B65D25/08
CPC分类号： B65D51/2871 , B65D47/141
摘要： The present invention discloses a sleeved to press-open type storage device with a prestressed to open closure having the closure and one side of the storage device connectedly attached by a flexible flake type structure, wherein it is characterized in that the relative stable relationship is that when the closure is closed relative to the storage device, the connecting flake type structure is bent to appear a prestressed status to opening direction thereby keeping the closure to remain at a stable opening status after it is pressed to open.

8. 发明授权

US08412785B2 Instant messaging system and method 有权
公开(公告)号：US08412785B2
公开(公告)日：2013-04-02
申请号：US12414523
申请日：2009-03-30
申请人： Xiaoguang Wu , Yang Chen , Yejun Huang , Huateng Ma , Liqing Zeng
发明人： Xiaoguang Wu , Yang Chen , Yejun Huang , Huateng Ma , Liqing Zeng
IPC分类号： G06F15/16
CPC分类号： H04L51/043 , H04L29/06 , H04L51/04 , H04L51/066 , H04L51/38 , H04L67/02 , H04L67/24 , H04L69/329 , H04W4/12 , H04W88/184
摘要： Methods and apparatuses for processing an instant message from a source wireless communication device to a destination device are described herein. In one aspect of the invention, an exemplary method includes receiving the instant message from the source wireless communication device, the instant message having a source wireless communication identifier, a destination instant messenger identifier, and data contents; extracting the source wireless communication identifier, the destination instant messenger identifier and the data contents from the instant message; retrieving a source instant messenger identifier corresponding to the source wireless communication identifier; binding the source instant messenger identifier with the source wireless communication identifier; and transmitting the data contents with the source instant messenger identifier to the destination device over a communication network, based on the destination instant messenger identifier. Other methods and apparatuses are also described.

9. 发明授权

US08190182B2 Instant messaging system and method 有权
标题翻译：即时通讯系统和方法
公开(公告)号：US08190182B2
公开(公告)日：2012-05-29
申请号：US12414505
申请日：2009-03-30
申请人： Xiaoguang Wu , Yang Chen , Yejun Huang , Huateng Ma , Liqing Zeng
发明人： Xiaoguang Wu , Yang Chen , Yejun Huang , Huateng Ma , Liqing Zeng
IPC分类号： H04W4/00
CPC分类号： H04L51/043 , H04L29/06 , H04L51/04 , H04L51/066 , H04L51/38 , H04L67/02 , H04L67/24 , H04L69/329 , H04W4/12 , H04W88/184
摘要： Methods and apparatuses for processing an instant message from a source wireless communication device to a destination device are described herein. In one aspect of the invention, an exemplary method includes receiving the instant message from the source wireless communication device, the instant message having a source wireless communication identifier, a destination instant messenger identifier, and data contents; extracting the source wireless communication identifier, the destination instant messenger identifier and the data contents from the instant message; retrieving a source instant messenger identifier corresponding to the source wireless communication identifier; binding the source instant messenger identifier with the source wireless communication identifier; and transmitting the data contents with the source instant messenger identifier to the destination device over a communication network, based on the destination instant messenger identifier. Other methods and apparatuses are also described.
摘要翻译：本文描述了用于处理来自源无线通信设备到目的地设备的即时消息的方法和设备。在本发明的一个方面，一种示例性方法包括从源无线通信设备接收即时消息，该即时消息具有源无线通信标识符，目的地即时消息标识符和数据内容; 从即时消息中提取源无线通信标识符，目的地即时消息标识符和数据内容; 检索与所述源无线通信标识符相对应的源即时消息标识符; 将源即时消息器标识符与源无线通信标识符绑定; 以及基于所述目的地即时消息标识符，通过通信网络将所述源即时消息传递者标识符的数据内容发送到所述目的地设备。还描述了其它方法和装置。

10. 发明授权

US08190181B2 Instant messaging system and method 有权
公开(公告)号：US08190181B2
公开(公告)日：2012-05-29
申请号：US12401435
申请日：2009-03-10
申请人： Xiaoguang Wu , Yang Chen , Yejun Huang , Huateng Ma , Liqing Zeng
发明人： Xiaoguang Wu , Yang Chen , Yejun Huang , Huateng Ma , Liqing Zeng
IPC分类号： H04W4/00
CPC分类号： H04L51/043 , H04L29/06 , H04L51/04 , H04L51/066 , H04L51/38 , H04L67/02 , H04L67/24 , H04L69/329 , H04W4/12 , H04W88/184
摘要： Methods and apparatuses for processing an instant message from a source wireless communication device to a destination device are described herein. In one aspect of the invention, an exemplary method includes receiving the instant message from the source wireless communication device, the instant message having a source wireless communication identifier, a destination instant messenger identifier, and data contents; extracting the source wireless communication identifier, the destination instant messenger identifier and the data contents from the instant message; retrieving a source instant messenger identifier corresponding to the source wireless communication identifier; binding the source instant messenger identifier with the source wireless communication identifier; and transmitting the data contents with the source instant messenger identifier to the destination device over a communication network, based on the destination instant messenger identifier. Other methods and apparatuses are also described.

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