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1. 发明申请

US20130231369A1 1-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives, preparation methods and uses thereof 有权
标题翻译： 1 - [（4-羟基哌啶-4-基）甲基]吡啶-2（1H） - 酮衍生物，其制备方法和用途
公开(公告)号：US20130231369A1
公开(公告)日：2013-09-05
申请号：US13697857
申请日：2011-04-08
申请人： Yunfeng Li , Rifang Yang , Youzhi Zhang , Yongzhen Li , Zengliang Jin , Peng Li , Li Yuan , Liuhong Yun , Nan Zhao , Cheng Zhang , Xiaodan Xu , Rusheng Zhao , Hongxia Chen , Rui Xue , Juanjuan Qin , Zhenzhen Wang , Jiazhi Yao
发明人： Yunfeng Li , Rifang Yang , Youzhi Zhang , Yongzhen Li , Zengliang Jin , Peng Li , Li Yuan , Liuhong Yun , Nan Zhao , Cheng Zhang , Xiaodan Xu , Rusheng Zhao , Hongxia Chen , Rui Xue , Juanjuan Qin , Zhenzhen Wang , Jiazhi Yao
IPC分类号： C07D401/06
CPC分类号： C07D401/06
摘要： Provided are N-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives represented by formula I, stereoisomers, pharmaceutically acceptable salts or solvates thereof. The above compounds have the dual activities of 5-hydroxytryptamine 1A receptor ligand and selective serotonin reuptake inhibitor. The preparation methods of the above compounds, the uses of these compounds for the prevention or treatment of nervous system diseases related to 5-hydroxytryptamine system dysfunction and the pharmaceutical compositions containing these compounds are also provided.
摘要翻译：提供由式I表示的N - [（4-羟基哌啶-4-基）甲基]吡啶-2（1H） - 酮衍生物，其立体异构体，药学上可接受的盐或溶剂合物。上述化合物具有5-羟色胺1A受体配体和选择性5-羟色胺再摄取抑制剂的双重活性。还提供了上述化合物的制备方法，这些化合物用于预防或治疗与5-羟色胺系统功能障碍有关的神经系统疾病的用途和含有这些化合物的药物组合物。

2. 发明授权

US08921563B2 1-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives, preparation methods and uses thereof 有权
标题翻译： 1 - [（4-羟基哌啶-4-基）甲基]吡啶-2（1H） - 酮衍生物，其制备方法和用途
公开(公告)号：US08921563B2
公开(公告)日：2014-12-30
申请号：US13697857
申请日：2011-04-08
申请人： Yunfeng Li , Rifang Yang , Youzhi Zhang , Yongzhen Li , Zengliang Jin , Peng Li , Li Yuan , Liuhong Yun , Nan Zhao , Cheng Zhang , Xiaodan Xu , Rusheng Zhao , Hongxia Chen , Rui Xue , Juanjuan Qin , Zhenzhen Wang , Jiazhi Yao
发明人： Yunfeng Li , Rifang Yang , Youzhi Zhang , Yongzhen Li , Zengliang Jin , Peng Li , Li Yuan , Liuhong Yun , Nan Zhao , Cheng Zhang , Xiaodan Xu , Rusheng Zhao , Hongxia Chen , Rui Xue , Juanjuan Qin , Zhenzhen Wang , Jiazhi Yao
IPC分类号： A61K31/445 , A61K31/505 , C07D211/68 , C07D239/02 , C07D401/06
CPC分类号： C07D401/06
摘要： Provided are N-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives represented by formula I, stereoisomers, pharmaceutically acceptable salts or solvates thereof. The above compounds have the dual activities of 5-hydroxytryptamine 1A receptor ligand and selective serotonin reuptake inhibitor. The preparation methods of the above compounds, the uses of these compounds for the prevention or treatment of nervous system diseases related to 5-hydroxytryptamine system dysfunction and the pharmaceutical compositions containing these compounds are also provided.
摘要翻译：提供由式I表示的N - [（4-羟基哌啶-4-基）甲基]吡啶-2（1H） - 酮衍生物，其立体异构体，药学上可接受的盐或溶剂合物。上述化合物具有5-羟色胺1A受体配体和选择性5-羟色胺再摄取抑制剂的双重活性。还提供了上述化合物的制备方法，这些化合物用于预防或治疗与5-羟色胺系统功能障碍有关的神经系统疾病的用途和含有这些化合物的药物组合物。

3. 发明申请

US20140258496A1 DATA CENTRE SYSTEM AND METHOD FOR A DATA CENTRE TO PROVIDE SERVICE 有权
标题翻译：数据中心系统和数据中心提供服务的方法
公开(公告)号：US20140258496A1
公开(公告)日：2014-09-11
申请号：US14346653
申请日：2012-07-17
申请人： Jiaoren Wu , Tao Liu , Ning Liu , Cheng Zhang , Jiang Fu
发明人： Jiaoren Wu , Tao Liu , Ning Liu , Cheng Zhang , Jiang Fu
IPC分类号： H04L12/803
CPC分类号： H04L47/125 , H04L29/06 , H04L61/1511 , H04L61/251 , H04L61/2528 , H04L61/6086 , H04L67/1002 , H04L67/1023
摘要： A data center system and a method for a data center to provide service are provided. The data center system comprises at least one first load balancing device, a plurality of second load balancing devices, and a plurality of servers. The first load balancing device is configured to transmit the first type network request to one of the plurality of second load balancing devices with a first scheduling strategy. The second load balancing device is configured to convert the first type network request to a second type network request, and to transmit the second type network request after the source address and destination address translation to one of the plurality of servers with a second scheduling strategy. The server is configured to generate a second type network response according to the second type network request and to return the second type network response to a corresponding second load balancing device.
摘要翻译：提供数据中心系统和数据中心提供服务的方法。数据中心系统包括至少一个第一负载平衡装置，多个第二负载平衡装置和多个服务器。第一负载平衡装置被配置为以第一调度策略将第一类型网络请求发送到多个第二负载平衡装置之一。第二负载平衡装置被配置为将第一类型网络请求转换为第二类型网络请求，并且在源地址和目的地地址转换之后，以第二调度策略向多个服务器之一发送第二类型网络请求。服务器被配置为根据第二类型网络请求生成第二类型网络响应，并且将第二类型网络响应返回到对应的第二负载平衡设备。

4. 发明授权

US08445563B2 Utilization of kraft lignin in phenol/formaldehyde bonding resins for OSB 有权
公开(公告)号：US08445563B2
公开(公告)日：2013-05-21
申请号：US12947703
申请日：2010-11-16
申请人： Jack G. Winterowd , Cheng Zhang , Amar N. Neogi
发明人： Jack G. Winterowd , Cheng Zhang , Amar N. Neogi
IPC分类号： C08L97/02 , C08K5/13
CPC分类号： C08L97/02 , C08L61/06 , C08L97/005
摘要： A resin for OSB comprising an aqueous resole reaction product of phenol, formaldehyde, alkaline metal hydroxide or carbonate, urea and a degraded lignin polymer having 35-65% solids, a pH of 8-13 and a viscosity 50-1000 centipoises. The phenol and formaldehyde are present in a molar ratio of 1.5 to 3.4 moles formaldehyde to 1 mole phenol and are 40 to 85% of the total solids added to the mixture. In one embodiment they are 50 to 75% of the total solids added to the mixture. The alkaline metal hydroxide or carbonate are 5 to 20% of the total solids added to the mixture. Urea is 5 to 35% of the total solids added to the mixture. The degraded lignin is 5 to 20% of the total solids added to the mixture.A method for making the resin and a product using the resin.

5. 发明授权

US08318122B2 Preparation of a carbon nanomaterial using a reverse microemulsion 失效
标题翻译：使用反相微乳液制备碳纳米材料
公开(公告)号：US08318122B2
公开(公告)日：2012-11-27
申请号：US12248993
申请日：2008-10-10
申请人： Cheng Zhang , Bing Zhou
发明人： Cheng Zhang , Bing Zhou
IPC分类号： C01B31/02 , B82B3/00
CPC分类号： B82Y30/00 , C01B32/05
摘要： Powdered, amorphous carbon nanomaterials are formed from a carbon precursor in reverse microemulsion that includes organic solvent, surfactant and water. Methods for manufacturing amorphous, powdered carbon nanomaterials generally include steps of (1) forming a reverse microemulsion including at least one non-polar solvent, at least one surfactant, and at least one polar solvent, (2) adding at least one carbon precursor substance to the reverse microemulsion, (3) reacting the at least one carbon precursor substance so as to form an intermediate carbon nanomaterial, (4) separating the intermediate amorphous carbon nanomaterial from the reverse microemulsion, and (5) heating the intermediate amorphous carbon nanomaterial for a period of time so as to yield an amorphous, powdered carbon nanomaterial. Amorphous, powdered carbon nanomaterials manufactured according to the present disclosure typically have a surface area of at least 500 m2/g, a graphitic content of at least 25%, and a conductivity of at least 150 S/m.
摘要翻译：粉末状无定形碳纳米材料由反相微乳液中的碳前体形成，其包括有机溶剂，表面活性剂和水。制造无定形粉末状碳纳米材料的方法通常包括以下步骤：（1）形成包含至少一种非极性溶剂，至少一种表面活性剂和至少一种极性溶剂的反相微乳液，（2）加入至少一种碳前体物质（3）使至少一种碳前体物质反应以形成中间碳纳米材料，（4）将中间无定形碳纳米材料与反相微乳液分离，（5）将中间无定形碳纳米材料加热至一段时间以产生无定形的粉末状碳纳米材料。根据本公开制造的无定形粉末碳纳米材料通常具有至少500m 2 / g的表面积，至少25％的石墨含量和至少150S / m的电导率。

6. 发明授权

US08131365B2 Event-based battery monitor for implantable devices 有权
标题翻译：基于事件的可植入式电池监视器
公开(公告)号：US08131365B2
公开(公告)日：2012-03-06
申请号：US12492416
申请日：2009-06-26
申请人： Cheng Zhang , Keith R. Maile
发明人： Cheng Zhang , Keith R. Maile
IPC分类号： A61N1/00
CPC分类号： A61N1/378 , A61N1/3708 , A61N1/37288 , G01R31/362 , G01R31/3648
摘要： A remaining charge capacity of a battery having an initial charge capacity is monitored. The battery powers a remote implantable medical device (IMD) that includes an active state, during which the remote IMD performs at least one function, and an inactive state, during which the remote IMD performs no functions. An active state charge consumption is computed based on stored parameters associated with an operational charge consumption for each function, and an inactive state charge consumption is computed based on a leakage current associated with the inactive state and a time the remote IMD is in the inactive state. The active state charge consumption and inactive state charge consumption are subtracted from the initial charge capacity to determine the remaining charge capacity.
摘要翻译：监视具有初始充电容量的电池的剩余充电容量。电池为远程可植入医疗设备（IMD）供电，该远程可植入医疗设备（IMD）包括活动状态，在该状态期间，远程IMD执行至少一个功能，以及非活动状态，在该状态期间，远程IMD不执行功能。基于与每个功能的操作电荷消耗相关联的存储参数来计算活动状态电荷消耗，并且基于与非活动状态相关联的泄漏电流和远程IMD处于非活动状态的时间来计算非活动状态电荷消耗。从初始充电容量中减去活动状态电荷消耗和无效状态电荷消耗，以确定剩余充电容量。

7. 发明授权

US08036173B2 System and method for managing wireless base station handoff information 失效
标题翻译：用于管理无线基站切换信息的系统和方法
公开(公告)号：US08036173B2
公开(公告)日：2011-10-11
申请号：US11651307
申请日：2007-01-09
申请人： Cheng Zhang , Heng Pan , Yanjun Yin
发明人： Cheng Zhang , Heng Pan , Yanjun Yin
IPC分类号： H04Q1/00
CPC分类号： H04W8/20 , H04W36/08
摘要： The present invention is directed to a system and method which base stations send informational messages to neighbor base stations when conditions change, so that the neighbor base stations can update its database to keep itself current on the parameters (including availability, traffic load, modulation scheme, etc.) to use in effecting efficient base station to base station handoffs. In one embodiment, the receiving base station marks the time of the received message from a neighbor base station and if a new updated message is not received within a time window then the receiving base station assumes that there is a problem with that neighbor.
摘要翻译：本发明涉及一种系统和方法，当条件改变时，基站向相邻基站发送信息消息，使得邻近基站可以更新其数据库以保持自身最新的参数（包括可用性，业务负载，调制方案等）用于实现有效的基站到基站切换。在一个实施例中，接收基站标记来自相邻基站的接收到的消息的时间，并且如果在时间窗口内没有接收到新的更新的消息，则接收基站假设该邻居存在问题。

8. 发明授权

US08027724B2 Hypertension diagnosis and therapy using pressure sensor 有权
标题翻译：高血压诊断和治疗使用压力传感器
公开(公告)号：US08027724B2
公开(公告)日：2011-09-27
申请号：US11833435
申请日：2007-08-03
申请人： Xuan Wei , Cheng Zhang , Shantha Arcot-Krishnamurthy , Dan Li
发明人： Xuan Wei , Cheng Zhang , Shantha Arcot-Krishnamurthy , Dan Li
IPC分类号： A61N1/08
CPC分类号： A61N1/36564 , A61B5/0031 , A61B5/0215 , A61N1/36114 , A61N1/36117
摘要： An example relates to a method for sensing a pulmonary artery pressure (PAP) and providing a sensed PAP signal, detecting an abnormal blood pressure (BP) condition using information from the sensed PAP signal, delivering a pacing energy to a heart, and automatically altering at least one pacing characteristic in response to the detected abnormal BP condition. The detecting an abnormal BP condition can include detecting various forms of hypertension or hypotension. The automatically altering the at least one pacing characteristic can include automatically altering at least one of a pacing rate, a pacing waveform, an atriventricular (AV) delay, an interventricular (VV) delay, a pacing mode, or a pacing site. The method can also include delivering vagal nerve stimulation and automatically altering the vagal nerve stimulation in response to the detected abnormal BP condition. The detecting the abnormal BP condition can also include using a sensed auxiliary physiological parameter.
摘要翻译：一个例子涉及一种用于感测肺动脉压（PAP）并提供感测到的PAP信号的方法，使用来自感测到的PAP信号的信息检测异常血压（BP）状况，将起搏能量递送到心脏，并且自动改变响应于检测到的异常BP状况的至少一个起搏特征。检测异常BP病症可包括检测各种形式的高血压或低血压。自动改变至少一个起搏特征可以包括自动改变起搏速率，起搏波形，房室（AV）延迟，心室间（VV）延迟，起搏模式或起搏部位中的至少一个。该方法还可以包括递送迷走神经刺激并响应于检测到的异常BP状况自动改变迷走神经刺激。检测异常BP状况还可以包括使用感测的辅助生理参数。

9. 发明申请

US20110157940A1 POWER FACTOR CORRECTOR WITH HIGH POWER FACTOR AT LOW LOAD OR HIGH MAINS VOLTAGE CONDITIONS 有权
标题翻译：功率因数校正器，具有低负载或高电压电压条件下的高功率因数
公开(公告)号：US20110157940A1
公开(公告)日：2011-06-30
申请号：US12647958
申请日：2009-12-28
申请人： Cheng Zhang
发明人： Cheng Zhang
IPC分类号： H02M7/06
CPC分类号： H02M1/4225 , G05F5/00 , H02M3/156 , H02M2001/0025 , H02M2001/0032 , Y02B70/126 , Y02B70/16
摘要： Various exemplary embodiments relate to a power factor corrector for low loads and a related method. The power factor corrector raises power factor at low loads or high mains voltages by having the a greater amount of current delivered to the load during the falling time of the absolute value of the mains AC voltage than during the applicable rising time. Various embodiments achieve this by increasing the switch-on time of a control switch during the falling time so that the majority of the switch-on time during a mains period occurs during the falling time. This may involve using a timing voltage increasing over a period within each half mains cycle to increase the switch-on time of conversion cycles in the falling time. This may also involve shifting the power conversion in time domain during each half mains cycle so that a majority of the time occurs during the falling time. Various embodiments may employ both methods.
摘要翻译：各种示例性实施例涉及用于低负载的功率因数校正器和相关方法。功率因数校正器通过在电源交流电压的绝对值的下降时间内比在适用的上升时间内具有更大量的电流传送到负载来提高低负载或高电源电压下的功率因数。各种实施例通过在下降时间期间增加控制开关的接通时间来实现这一点，使得在电力周期期间的大部分接通时间在下降时间期间发生。这可能涉及使用在每个半电源周期内的周期上增加的定时电压以在下降时间内增加转换周期的接通时间。这也可能涉及在每个半电源周期期间在时域中移动功率转换，使得大部分时间在下降时间内发生。各种实施例可以采用两种方法。

10. 发明申请

US20110068713A1 METHOD AND CIRCUIT ARRANGEMENT FOR CYCLE-BY-CYCLE CONTROL OF A LED CURRENT FLOWING THROUGH A LED CIRCUIT ARRANGEMENT, AND ASSOCIATED CIRCUIT COMPOSITION AND LIGHTING SYSTEM 有权
标题翻译：通过LED电路布置的LED电流循环周期控制的方法和电路布置，以及相关电路组成和照明系统
公开(公告)号：US20110068713A1
公开(公告)日：2011-03-24
申请号：US12992091
申请日：2009-05-06
申请人： Gian Hoogzaad , Wilhelmus H. M. Langeslag , Frans Pansier , Cheng Zhang
发明人： Gian Hoogzaad , Wilhelmus H. M. Langeslag , Frans Pansier , Cheng Zhang
IPC分类号： H05B41/36
CPC分类号： H05B33/0815 , H05B33/083
摘要： The invention provides a method for cycle-by-cycle control of a LED current (ILED) flowing through a LED circuit arrangement (LEDCIRC) at a mean LED current level. The method comprises a) establishing a converter current (IL), b) establishing an oscillation of the converter current (IL) between substantially a valley current level and substantially a peak current level, c) feeding the LED circuit arrangement (LEDCIRC) with the converter current (IL) as the LED current during a part of an oscillation cycle of the oscillation of the converter current, d) determining a current level correction for compensating a current level error between an integral over an oscillation cycle of the LED current and a reference, the reference being representative of the mean LED current level, and e) adjusting at least one of the valley current level and the peak current level with the current level correction for use in a successive cycle of the oscillation of the converter current. The invention also provides a circuit arrangement operable for using the method, a LED driver IC using the circuit arrangement, a circuit composition with at least one LED and the circuit arrangement, and a lighting system with the circuit composition.
摘要翻译：本发明提供了一种在平均LED电流水平下逐步控制流过LED电路装置（LEDCIRC）的LED电流（ILED）的方法。该方法包括：a）建立转换器电流（IL），b）建立基本上谷值电流水平和基本上峰值电流水平之间的转换器电流（IL）的振荡，c）将LED电路装置（LEDCIRC）馈送到在转换器电流的振荡的振荡周期的一部分期间，转换器电流（IL）作为LED电流，d）确定用于补偿LED电流的振荡周期之间的积分和电流水平误差的电流电平校正，参考，该参考代表平均LED电流电平，以及e）利用当前电平校正来调整谷电流电平和峰值电流电平中的至少一个，以用于转换器电流的振荡的连续循环。本发明还提供一种可用于使用该方法的电路装置，使用电路装置的LED驱动器IC，具有至少一个LED的电路组合和电路装置，以及具有电路组成的照明系统。

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