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1. 发明授权

US08263796B2 Process for production of cyanohydrin compound, and process for production of α-hydroxyester compound 有权
标题翻译：氰醇化合物的制造方法以及α-羟基酯化合物的制造方法
公开(公告)号：US08263796B2
公开(公告)日：2012-09-11
申请号：US12734255
申请日：2008-10-21
申请人： Naoki Fujiwara , Kazuya Nakagawa , Yuichiro Kinoshita , Koji Midorikawa
发明人： Naoki Fujiwara , Kazuya Nakagawa , Yuichiro Kinoshita , Koji Midorikawa
IPC分类号： C07C253/30 , C07C69/003
CPC分类号： C07C253/00 , C07C67/22 , C07C69/675 , C07C255/16 , C07C255/36
摘要： A process according to the present invention for producing a cyanohydrin compound is a process for producing a cyanohydrin compound by performing a reaction between a carbonyl compound such as an aldehyde compound and hydrogen cyanide in the presence of a catalyst, a content of the carbonyl compound in a reaction system being not more than 50 mol % with respect to the cyanohydrin compound. Thus provided is a process for producing a cyanohydrin compound in good yield from an aldehyde compound and hydrogen cyanide.
摘要翻译：根据本发明的用于制备氰醇化合物的方法是通过在催化剂存在下，通过在醛化合物和氰化氢等羰基化合物之间进行反应来制备氰腈化合物的方法，羰基化合物的含量反应体系相对于氰醇化合物为50摩尔％以下。因此提供了由醛化合物和氰化氢以良好的产率制备羟腈化合物的方法。

2. 发明申请

US20100256409A1 PROCESS FOR PRODUCTION OF CYANOHYDRIN COMPOUND, AND PROCESS FOR PRODUCTION OF ALPHA HYDROXYESTER COMPOUND 有权
标题翻译：氰胺化合物的生产方法和制备ALPHA羟基酯化合物的方法
公开(公告)号：US20100256409A1
公开(公告)日：2010-10-07
申请号：US12734255
申请日：2008-10-21
申请人： Naoki Fujiwara , Kazuya Nakagawa , Yuichiro Kinoshita , Koji Midorikawa
发明人： Naoki Fujiwara , Kazuya Nakagawa , Yuichiro Kinoshita , Koji Midorikawa
IPC分类号： C07C253/30 , C07C69/003
CPC分类号： C07C253/00 , C07C67/22 , C07C69/675 , C07C255/16 , C07C255/36
摘要： A process according to the present invention for producing a cyanohydrin compound is a process for producing a cyanohydrin compound by performing a reaction between a carbonyl compound such as an aldehyde compound and hydrogen cyanide in the presence of a catalyst, a content of the carbonyl compound in a reaction system being not more than 50 mol % with respect to the cyanohydrin compound. Thus provided is a process for producing a cyanohydrin compound in good yield from an aldehyde compound and hydrogen cyanide.
摘要翻译：根据本发明的用于制备氰醇化合物的方法是通过在催化剂存在下，通过在醛化合物和氰化氢等羰基化合物之间进行反应来制备氰腈化合物的方法，羰基化合物的含量反应体系相对于氰醇化合物为50摩尔％以下。因此提供了由醛化合物和氰化氢以良好的产率制备羟腈化合物的方法。

3. 发明授权

US08471053B2 Process and apparatus for production of cyanohydrin compound, and process for production of α-hydroxyester compound 有权
标题翻译：制备氰醇化合物的方法和设备，以及α-羟基酯化合物的制备方法
公开(公告)号：US08471053B2
公开(公告)日：2013-06-25
申请号：US12734258
申请日：2008-10-21
申请人： Yuichiro Kinoshita , Naoki Fujiwara , Kazuya Nakagawa , Koji Midorikawa
发明人： Yuichiro Kinoshita , Naoki Fujiwara , Kazuya Nakagawa , Koji Midorikawa
IPC分类号： C07C253/08
CPC分类号： C07C253/00 , C07C67/22 , C07C69/675 , C07C255/16 , C07C255/36
摘要： A process according to the present invention for producing a cyanohydrin compound flow-reacts a carbonyl compound with hydrogen cyanide in the presence of a catalyst, and can therefore reduce the residence time. This makes it possible to reduce the period of time over which the resulting cyanohydrin compound is exposed to an unreacted portion of the carbonyl compound. As a result, the resulting cyanohydrin compound can be prevented from reacting with the unreacted portion. This makes it possible to produce the cyanohydrin compound in good yield. That is, the process according to the present invention for producing a cyanohydrin compound produces a cyanohydrin compound in good yield from a carbonyl compound and hydrogen cyanide.
摘要翻译：根据本发明的用于生产氰醇化合物的方法在催化剂存在下与氰化氢流动反应，因此可以减少停留时间。这使得可以减少所得羟腈化合物暴露于羰基化合物的未反应部分的时间。结果，可以防止所得羟腈化合物与未反应部分反应。这使得可以以良好的产率生产羟腈化合物。也就是说，根据本发明的用于制备羟腈化合物的方法由羰基化合物和氰化氢以良好的产率产生羟腈化合物。

4. 发明申请

US20100261929A1 PROCESS AND APPARATUS FOR PRODUCTION OF CYANOHYDRIN COMPOUND, AND PROCESS FOR PRODUCTION OF ALPHA-HYDROXYESTER COMPOUND 有权
标题翻译：用于生产氰氰化合物的方法和装置，以及用于生产α-羟基化合物的方法
公开(公告)号：US20100261929A1
公开(公告)日：2010-10-14
申请号：US12734258
申请日：2008-10-21
申请人： Yuichiro Kinoshita , Naoki Fujiwara , Kazuya Nakagawa , Koji Midorikawa
发明人： Yuichiro Kinoshita , Naoki Fujiwara , Kazuya Nakagawa , Koji Midorikawa
IPC分类号： C07C253/30 , C07C67/00 , B01J8/02
CPC分类号： C07C253/00 , C07C67/22 , C07C69/675 , C07C255/16 , C07C255/36
摘要： A process according to the present invention for producing a cyanohydrin compound flow-reacts a carbonyl compound with hydrogen cyanide in the presence of a catalyst, and can therefore reduce the residence time. This makes it possible to reduce the period of time over which the resulting cyanohydrin compound is exposed to an unreacted portion of the carbonyl compound. As a result, the resulting cyanohydrin compound can be prevented from reacting with the unreacted portion. This makes it possible to produce the cyanohydrin compound in good yield. That is, the process according to the present invention for producing a cyanohydrin compound produces a cyanohydrin compound in good yield from a carbonyl compound and hydrogen cyanide.
摘要翻译：根据本发明的用于生产氰醇化合物的方法在催化剂存在下与氰化氢流动反应，因此可以减少停留时间。这使得可以减少所得羟腈化合物暴露于羰基化合物的未反应部分的时间。结果，可以防止所得羟腈化合物与未反应部分反应。这使得可以以良好的产率生产羟腈化合物。也就是说，根据本发明的用于制备羟腈化合物的方法由羰基化合物和氰化氢以良好的产率产生羟腈化合物。

5. 发明授权

US07705175B2 Method for producing imide ether compound 有权
标题翻译：生产酰亚胺醚化合物的方法
公开(公告)号：US07705175B2
公开(公告)日：2010-04-27
申请号：US11795404
申请日：2006-01-18
申请人： Hitoshi Mitsui , Yuichiro Kinoshita , Kazuya Nakagawa
发明人： Hitoshi Mitsui , Yuichiro Kinoshita , Kazuya Nakagawa
IPC分类号： C07C249/00
CPC分类号： C07C257/06
摘要： Provided is a method for producing an imide ether compound in high yield. The method is characterized in that a nitrile compound, an alcohol, and a hydrogen halide are continuously introduced into a flow reaction device comprising a mixer and a flow reactor, to be subjected to a reaction. Because a reaction proceeds in a ratio of 1:1 by a flow reactor, selectivity is improved and generation of by-products is decreased, and thus an imide ether compound can be efficiently produced.
摘要翻译：提供以高产率制备酰亚胺醚化合物的方法。该方法的特征在于将腈化合物，醇和卤化氢连续地引入到包含混合器和流动反应器的流动反应装置中以进行反应。由于流动反应器以1:1的比例进行反应，所以选择性提高，副产物的产生降低，能够有效地制造酰亚胺醚化合物。

6. 发明申请

US20090005599A1 Method for Producing Imide Ether Compound 有权
标题翻译：生产酰亚胺醚化合物的方法
公开(公告)号：US20090005599A1
公开(公告)日：2009-01-01
申请号：US11795404
申请日：2006-01-18
申请人： Hitoshi Mitsui , Yuichiro Kinoshita , Kazuya Nakagawa
发明人： Hitoshi Mitsui , Yuichiro Kinoshita , Kazuya Nakagawa
IPC分类号： C07C211/03
CPC分类号： C07C257/06
摘要： Provided is a method for producing an imide ether compound in high yield. The method is characterized in that a nitrile compound, an alcohol, and a hydrogen halide are continuously introduced into a flow reaction device comprising a mixer and a flow reactor, to be subjected to a reaction. Because a reaction proceeds in a ratio of 1:1 by a flow reactor, selectivity is improved and generation of by-products is decreased, and thus an imide ether compound can be efficiently produced.
摘要翻译：提供以高产率制备酰亚胺醚化合物的方法。该方法的特征在于将腈化合物，醇和卤化氢连续地引入到包含混合器和流动反应器的流动反应装置中以进行反应。由于流动反应器以1:1的比例进行反应，所以选择性提高，副产物的产生降低，能够有效地制造酰亚胺醚化合物。

7. 发明申请

US20140128585A1 FRUCTOSE ABSORPTION INHIBITOR 审中-公开
标题翻译：胶体吸收抑制剂
公开(公告)号：US20140128585A1
公开(公告)日：2014-05-08
申请号：US14130104
申请日：2012-07-06
申请人： Keiichiro Sugimoto , Hiroto Nakayama , Kazuya Nakagawa , Syuichi Hayashi
发明人： Keiichiro Sugimoto , Hiroto Nakayama , Kazuya Nakagawa , Syuichi Hayashi
IPC分类号： A61K31/7024 , A23K1/16 , A23L1/30
CPC分类号： A61K31/7024 , A23K20/111 , A23L33/105 , A23L33/20 , A61K31/7042 , A61K31/7048
摘要： A fructose absorption inhibitor according to the present invention comprises a hydrolyzable tannin as an active ingredient. The hydrolyzable tannin preferably has a form composed of a gallic acid derivative and/or an ellagic acid derivative bound to a hydroxy group in glucose via an ester bond, and includes ellagitannin, gallotannin and so on.
摘要翻译：根据本发明的果糖吸收抑制剂包含可水解的单宁作为活性成分。可水解的单宁优选具有通过酯键与葡萄糖中的羟基结合的没食子酸衍生物和/或鞣花酸衍生物形成的形式，并且包括鞣花素，鞣兰宁等。

8. 发明授权

US07565826B2 Gas sensor 失效
标题翻译：气体传感器
公开(公告)号：US07565826B2
公开(公告)日：2009-07-28
申请号：US11651071
申请日：2007-01-09
申请人： Kazuya Nakagawa
发明人： Kazuya Nakagawa
IPC分类号： G01N7/00
CPC分类号： G01N27/407
摘要： A gas sensor is disclosed as having a gas sensor element, supported with a cylindrical housing, which is covered with an atmosphere-side cover fixedly secured to the cylindrical housing. The atmosphere-side cover fixedly supports a seal member having a ventilation bore and a plurality of lead wire inserting bores formed around the ventilation bore. A filter member is fusion bonded to the seal member in a fusion-bonded area at temperatures above 300° C. The fusion-bonded area is formed in an entire circumference in gastight effect at an area outside an outer periphery of the ventilation bore and has no clearance, wherein suppose that the ventilation bore has an opening surface area A at the end face of the seal member and a region surrounded with the fusion-bonded area has a surface area B, the relationship is established as A
摘要翻译：公开了一种气体传感器，其具有由圆柱形壳体支撑的气体传感器元件，该气体传感器元件被固定地固定到圆柱形壳体上的气氛侧盖子覆盖。大气侧盖固定地支撑具有通风孔的密封构件和形成在通风孔周围的多个引线插入孔。过滤构件在高于300℃的温度下在熔接区域中熔融接合到密封构件。熔融区域在通气孔的外周侧的区域的气密效果的整个圆周上形成，并且具有没有间隙，其中假设通气孔在密封构件的端面处具有开口表面积A，并且被熔融区域包围的区域具有表面积B，则该关系被确定为A

9. 发明申请

US20070157939A1 Gas sensor 失效
标题翻译：气体传感器
公开(公告)号：US20070157939A1
公开(公告)日：2007-07-12
申请号：US11651071
申请日：2007-01-09
申请人： Kazuya Nakagawa
发明人： Kazuya Nakagawa
IPC分类号： A24D3/04
CPC分类号： G01N27/407
摘要： A gas sensor is disclosed as having a gas sensor element, supported with a cylindrical housing, which is covered with an atmosphere-side cover fixedly secured to the cylindrical housing. The atmosphere-side cover fixedly supports a seal member having a ventilation bore and a plurality of lead wire inserting bores formed around the ventilation bore. A filter member is fusion bonded to the seal member in a fusion-bonded area at temperatures above 300° C. The fusion-bonded area is formed in an entire circumference in gastight effect at an area outside an outer periphery of the ventilation bore and has no clearance, wherein suppose that the ventilation bore has an opening surface area A at the end face of the seal member and a region surrounded with the fusion-bonded area has a surface area B, the relationship is established as A
摘要翻译：公开了一种气体传感器，其具有由圆柱形壳体支撑的气体传感器元件，该气体传感器元件被固定地固定到圆柱形壳体上的气氛侧盖子覆盖。大气侧盖固定地支撑具有通风孔的密封构件和形成在通风孔周围的多个引线插入孔。过滤构件在高于300℃的温度下在熔接区域中熔融接合到密封构件。熔融区域在通气孔的外周侧的区域的气密效果的整个圆周上形成，并且具有没有间隙，其中假设通气孔在密封构件的端面处具有开口表面积A，并且被熔融区域包围的区域具有表面积B，则该关系被确定为A

10. 发明授权

US5467635A Gas chromatograph 失效
标题翻译：气相色谱仪
公开(公告)号：US5467635A
公开(公告)日：1995-11-21
申请号：US354789
申请日：1994-12-12
申请人： Kazuya Nakagawa , Toyoaki Fukushima
发明人： Kazuya Nakagawa , Toyoaki Fukushima
IPC分类号： G01N30/02 , G01N30/12 , G01N30/30 , G01N30/32 , B01D15/08 , G01N30/88
CPC分类号： G01N30/32 , G01N2030/025 , G01N2030/127 , G01N2030/3007 , G01N2030/324
摘要： A target pressure is calculated by a fluid dynamic theory using a length of the column, an inner diameter of the column and the temperature of the column so that the linear velocity of the gas flowing through the column is at a preset pre-determined value at which the HETP (height equivalent to a theoretical plate) value, as calculated from chemical kinematic theory, is the minimum and the resolution of the column is the highest. Then the pressure of the gas at the entrance of the column of a chromatograph is maintained at the calculated target pressure while the temperature of the column is raised to reduce the analyzing time.
摘要翻译：目标压力通过流体动力学理论计算，使用柱的长度，柱的内径和柱的温度，使得流过柱的气体的线速度处于预设的预定值由化学运动学理论计算出的HETP（理论塔板的高度）值是最小值，柱的分辨率最高。然后将色谱仪色谱柱入口处的气体压力保持在计算出的目标压力，同时升高色谱柱的温度以减少分析时间。

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