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1. 发明授权

US4101536A Muramyldipeptide derivatives and process for the preparation thereof 失效
标题翻译：胞壁酰二肽衍生物及其制备方法
公开(公告)号：US4101536A
公开(公告)日：1978-07-18
申请号：US809245
申请日：1977-06-23
申请人： Yuichi Yamamura , Tetsuo Shiba , Ichiro Azuma , Shoichi Kusumoto , Tadamasa Hirayama , Tsuneo Kusama
发明人： Yuichi Yamamura , Tetsuo Shiba , Ichiro Azuma , Shoichi Kusumoto , Tadamasa Hirayama , Tsuneo Kusama
IPC分类号： A61K38/14 , C07K9/00 , A61K37/00 , C07G7/00
CPC分类号： C07K9/005
摘要： Muramyldipeptide derivatives of the formula: ##STR1## wherein Y represents a mycoloyl group or a synthetic higher acyl group having total carbon number of C30-C90 and having at least a branched chain of long alkyl group on the .alpha.-position thereof,Q represents an -L-alanyl-D-isoglutamine group, a -glycyl-D-isoglutamine group or an -L-seryl-D-isoglutamine group;Salts of such derivatives; the method of preparing such derivatives and their salts; the derivatives and their salts having potent immunoadjuvant activities and antitumor activity and being applicable as the agent for the immunotherapy of cancer for humans and animals.
摘要翻译：其中Y表示总碳数为C30-C90并且在其α-位上具有至少一个长烷基的支链的合成的较高级酰基，其中Y代表一个或多个烷基， -L-丙氨酰-D-异谷氨酰胺基，α-甘氨酰-D-异谷氨酸胺基或-L-丝氨酰-D-异谷氨酰胺基; 这些衍生物的销售; 制备这些衍生物及其盐的方法; 衍生物及其具有免疫功能活动和抗肿瘤活性的药物，适用于人类和动物免疫球蛋白的代理。

2. 发明授权

US5006647A Phosphorus containing disaccharide derivatives 失效
标题翻译：含磷二糖衍生物
公开(公告)号：US5006647A
公开(公告)日：1991-04-09
申请号：US162932
申请日：1988-03-02
申请人： Tsuneo Kusama , Tsunehiko Soga , Tetsuo Shiba
发明人： Tsuneo Kusama , Tsunehiko Soga , Tetsuo Shiba
IPC分类号： A61K31/70 , C07H13/06 , C07H15/04
CPC分类号： C07H13/06 , C07H15/04
摘要： A disaccharide compound represented by formula (I): ##STR1## wherein R, R.sup.1, R.sup.2, R.sup.3, R.sup.4, and R.sup.5 are as defined in the specification and a salt thereof are disclosed. The compound exhibits excellent antitumor activity and low toxicity and is useful as an antitumor agent.

3. 发明授权

US5134230A 2-Deoxy-2-aminoglucopyranoside derivatives 失效
标题翻译： 2-脱氧-2-氨基吡喃糖苷衍生物
公开(公告)号：US5134230A
公开(公告)日：1992-07-28
申请号：US614417
申请日：1991-01-18
申请人： Tsuneo Kusama , Tsunehiko Soga , Tetsuo Shiba
发明人： Tsuneo Kusama , Tsunehiko Soga , Tetsuo Shiba
IPC分类号： C07H13/06 , C07H15/04
CPC分类号： C07H13/06 , C07H15/04
摘要： A disaccharide compound represented by formula (I): ##STR1## wherein R, R.sup.1, R.sup.2, R.sup.3, R.sup.4, and R.sup.5 are as defined in the specification and a salt thereof are disclosed. The compound exhibits excellent antitumor activity and low toxicity and is useful as an antitumor agent.
摘要翻译：由式（I）表示的二糖化合物：其中R，R 1，R 2，R 3，R 4和R 5如本说明书中所定义，及其盐。该化合物具有优异的抗肿瘤活性和低毒性，可用作抗肿瘤剂。

4. 发明授权

US4382080A Method for treating and preventing bacterial infections 失效
标题翻译：治疗和预防细菌感染的方法
公开(公告)号：US4382080A
公开(公告)日：1983-05-03
申请号：US262244
申请日：1981-05-11
申请人： Tetsuo Shiba , Yuichi Yamamura , Shozo Kotani , Osamu Nagase , Hidemasa Ogawa
发明人： Tetsuo Shiba , Yuichi Yamamura , Shozo Kotani , Osamu Nagase , Hidemasa Ogawa
IPC分类号： A61K38/00 , A61P31/04 , C07K9/00 , A61K37/00
CPC分类号： C07K9/005
摘要： A method for treating and preventing bacterial infections which comprises administering a 6-O-acylmuramyl depeptide of the formula: ##STR1## wherein X represents a divalent residual group of an amino acid such as L-alanine, L-serine, L-valine, etc., Y represents a residual group of a middle to higher fatty acid having 10 to 60 carbon atoms and isoGln represents a residual group of isoglutamine, or a pharmaceutical composition containing a 6-O-acylmuramyl dipeptide of the formula(I) as an active ingredient to a patient afflicted therewith.
摘要翻译：一种用于治疗和预防细菌感染的方法，其包括给予下式的6-O-酰基木瓜酰基多肽：其中X表示氨基酸的二价残基，例如L-丙氨酸，L-丝氨酸，L-缬氨酸， Y表示具有10〜60个碳原子的中等〜高级脂肪酸的残基，isoGln表示残留的异谷氨酰胺胺基，或含有式（I）的6-O-酰基月桂酰二肽作为对患有其的患者的活性成分。

5. 发明授权

US4317771A Muramyldipeptide derivatives 失效
标题翻译：胞壁酰二肽衍生物
公开(公告)号：US4317771A
公开(公告)日：1982-03-02
申请号：US162233
申请日：1980-06-23
申请人： Tetsuo Shiba , Shozo Kotani , Yuichi Yamamura , Osamu Nagase , Hidemasa Ogawa
发明人： Tetsuo Shiba , Shozo Kotani , Yuichi Yamamura , Osamu Nagase , Hidemasa Ogawa
IPC分类号： A61K38/00 , A61K39/39 , A61P31/04 , C07K9/00 , C07C103/52 , A61K39/00
CPC分类号： C07K9/005
摘要： Muramyldipeptide derivatives of the formula (I): ##STR1## wherein X represents an amino acid residue such as of L-alanine, L-serine, L-valine, glycine, etc., and Y represents a group ##STR2## wherein R.sub.1 represents a hydrogen atom, an alkyl group of 1 to 6 carbon atoms, a carboxamide group or a carboxyl group, n represents an integer of 1 to 6, A represents a straight or branched chain, saturated or unsaturated aliphatic hydrocarbon residue of 7 to 30 carbon atoms, and "Acyl" means an acyl group of an aliphatic carboxylic acid having 2 to 6 carbon atoms. These compounds have excellent adjuvant activity and/or prophylactic and therapeutic effects against microbial infections.
摘要翻译：式（I）的乳糖基二肽衍生物：其中X表示L-丙氨酸，L-丝氨酸，L-缬氨酸，甘氨酸等氨基酸残基，Y表示基团其中R1表示氢原子，1〜6个碳原子的烷基，羧酰胺基或羧基，n表示1〜6的整数，A表示7或6的直链或支链饱和或不饱和脂肪族烃残基 30个碳原子，“酰基”是指碳原子数2〜6的脂肪族羧酸的酰基。这些化合物具有优异的佐剂活性和/或对微生物感染的预防和治疗作用。

6. 发明申请

US20100303529A1 SHEET CONVEYING DEVICE OF IMAGE FORMING APPARATUS 审中-公开
标题翻译：图像形成装置的输送装置
公开(公告)号：US20100303529A1
公开(公告)日：2010-12-02
申请号：US12789354
申请日：2010-05-27
申请人： Tetsuo Shiba
发明人： Tetsuo Shiba
IPC分类号： G03G15/00 , B65H5/06
CPC分类号： B65H5/38 , B65H5/062 , B65H2404/52 , B65H2404/6111 , B65H2801/06 , G03G15/6558
摘要： A conveying device includes a first curved guide member, a second guide member which has a radius of curvature larger than the first guide member and guides a recording medium between the second guide member and the first guide member, a pinching and conveying section which is disposed on an entrance side of a conveyance path including the first guide member and the second guide member, pinches the recording medium and conveys the recording medium into the conveyance path, and a support member which is provided on the second guide member at.a position adjacent to the pinching and conveying section, and has a support point on an extended line of a normal line of a nip of the pinching and conveying section.
摘要翻译：输送装置包括第一弯曲引导构件，第二引导构件，其具有比第一引导构件大的曲率半径，并且将记录介质引导到第二引导构件与第一引导构件之间;夹持和输送部，在包括第一引导构件和第二引导构件的输送路径的入口侧，夹持记录介质并将记录介质输送到输送路径中;以及支撑构件，其设置在邻近的位置处的第二引导构件上并且在夹持和输送部分的辊隙的法线延伸线上具有支撑点。

7. 发明授权

US07731183B2 Paper feeding apparatus with paper size detectors 有权
标题翻译：纸张尺寸检测器的送纸装置
公开(公告)号：US07731183B2
公开(公告)日：2010-06-08
申请号：US12207468
申请日：2008-09-09
申请人： Masahiro Ohno , Yousuke Ushiyama , Tokihiko Ise , Toshihiro Matsushima , Tetsuo Shiba
发明人： Masahiro Ohno , Yousuke Ushiyama , Tokihiko Ise , Toshihiro Matsushima , Tetsuo Shiba
IPC分类号： B65H1/00
CPC分类号： B65H1/266 , B65H2403/41 , B65H2403/51 , B65H2403/5331 , B65H2405/111 , B65H2405/31 , B65H2511/10 , B65H2511/20 , B65H2551/20 , B65H2220/01 , B65H2220/04
摘要： A paper feeding apparatus includes a cassette main body that stacks a paper therein, a sidewall that moves in a width direction of the cassette main body, an end wall that moves in a longitudinal direction of the cassette main body, a first movable member that is connected at one end to the sidewall and rotates around a shaft axially fixed to the cassette main body in connection with the sidewall, a second movable member that is connected at one end to the end wall and rotates around a shaft axially fixed to the cassette main body in connection with the end wall, a first detection unit that has a plurality of detection members and detects the size of the paper in the width direction, and a second detection unit that has a plurality of detection members and detects the size of the paper in the longitudinal direction.
摘要翻译：供纸装置包括：纸盒主体，其中纸张堆叠;沿着盒主体的宽度方向移动的侧壁;沿着盒主体的纵向方向移动的端壁;第一可移动部件; 在一端连接到侧壁并围绕与轴向固定到盒主体的轴旋转，第二可移动件在一端连接到端壁并围绕轴轴向地固定到盒主体与端壁相关联的第一检测单元，具有多个检测构件并检测纸宽度方向的尺寸的第一检测单元，以及具有多个检测构件并检测纸张尺寸的第二检测单元在纵向上。

8. 发明授权

US5805629A Semiconductor laser 失效
标题翻译：半导体激光器
公开(公告)号：US5805629A
公开(公告)日：1998-09-08
申请号：US747050
申请日：1996-11-12
申请人： Masayoshi Takemi , Tatsuya Kimura , Daisuke Suzuki , Tetsuo Shiba , Kimitaka Shibata
发明人： Masayoshi Takemi , Tatsuya Kimura , Daisuke Suzuki , Tetsuo Shiba , Kimitaka Shibata
IPC分类号： H01L21/20 , H01S5/00 , H01S5/20 , H01S5/22 , H01S5/227 , H01S5/323 , H01S3/19
CPC分类号： H01S5/227 , H01S5/2081 , H01S5/2201 , H01S5/2206 , H01S5/2275 , H01S5/32391
摘要： A semiconductor device includes a p type InP substrate with a (001) surface; a mesa structure formed by dry etching, extending along a direction, including semiconductor layers, having (110) side surfaces, and a height H.sub.m ; and mesa burying layers including a p type InP burying layer on the (110) side surfaces and the (001) surface, the p type InP burying layer having a thickness D.sub.p, and an n type InP burying layer on the p type InP burying layer. An angle between a (111)B surface and (001) surface is .theta..sub.111, the growth rates on the (110) side surfaces and on the (001) surface are respectively R.sub.g (110) and R.sub.g (001), an angle .theta. is tan .theta.=R.sub.g (110)/R.sub.g (001) and the critical thickness D.sub.n of the n type InP burying layer on the (001) surface when the n type InP burying layer is not grown on the (111)B surface is ##EQU1## The n type InP burying layer has a thickness D.ltoreq.D.sub.n. The leakage current path width is narrowed and contact of the n type InP burying layer and an uppermost layer of the semiconductor layers is avoided. Consequently, a semiconductor device having reduced leakage current and superior device characteristics is obtained.
摘要翻译：半导体器件包括具有（001）表面的p型InP衬底; 通过干蚀刻形成的台面结构，沿着<110>方向延伸，包括具有（1 + E，ov 1 + EE 0）侧表面的半导体层和高度Hm; （1 + E，ovs 1 + EE 0）侧表面和（001）表面的p型InP掩埋层和具有厚度Dp的p型InP掩埋层和n型InP掩埋层的台面掩埋层在p型InP埋层中。（111）B表面和（001）表面之间的角度为θ111，（1 + E，ovs 1 + EE 0）侧表面和（001）表面上的生长速率分别为Rg（1 + E ，ovs 1 + EE 0）和Rg（001），角度θ为tanθ= Rg（1 + E，ovs 1 + EE 0）/ Rg（001）和n型InP掩埋层的临界厚度Dn 在（111）B表面上未生长n型InP掩埋层时，（001）表面是n型InP掩埋层，其厚度D

9. 发明授权

US5316967A Method for producing semiconductor device 失效
标题翻译：半导体器件的制造方法
公开(公告)号：US5316967A
公开(公告)日：1994-05-31
申请号：US975109
申请日：1992-11-12
申请人： Nobuaki Kaneno , Hirotaka Kizuki , Norio Hayafuji , Tetsuo Shiba , Hitoshi Tada
发明人： Nobuaki Kaneno , Hirotaka Kizuki , Norio Hayafuji , Tetsuo Shiba , Hitoshi Tada
IPC分类号： H01L21/20 , H01L21/308 , H01S5/20 , H01S5/223 , H01S5/227 , H01S5/323
CPC分类号： H01L21/3081 , H01L21/02392 , H01L21/02395 , H01L21/02463 , H01L21/02505 , H01L21/02546 , H01L21/0262 , H01S5/2231 , H01S2304/04 , H01S5/2081 , H01S5/2277 , H01S5/32325
摘要： In a method for producing a semiconductor device, a first semiconductor layer is epitaxially grown on a semiconductor substrate, an insulating film pattern is formed on the first semiconductor layer, and portions of the first semiconductor layer are removed by wet etching using the insulating film pattern as a mask to leave a ridge having a reverse mesa shape and a width. Ends of the insulating film pattern are removed by etching to approximately the width of the ridge, a second semiconductor layer is epitaxially grown on opposite sides of the ridge, and a third semiconductor layer is epitaxially grown on the ridge and the second semiconductor layer. The second semiconductor layer is evenly grown without concave portions at opposite sides of the ridge. In addition, the third semiconductor layer is evenly grown on the ridge and the second semiconductor layer, and an electrode reliably connects the surface of the third semiconductor layer. A semiconductor device with good performance and high reliability is reproducibly manufactured.
摘要翻译：在制造半导体器件的方法中，在半导体衬底上外延生长第一半导体层，在第一半导体层上形成绝缘膜图案，并且通过使用绝缘膜图案的湿蚀刻去除第一半导体层的部分作为掩模，离开具有反台面形状和宽度的脊。绝缘膜图案的端部通过蚀刻到脊的宽度去除，在脊的相对侧上外延生长第二半导体层，并且在脊和第二半导体层上外延生长第三半导体层。第二半导体层在脊的相对侧均匀生长而没有凹部。此外，第三半导体层均匀地生长在脊和第二半导体层上，并且电极可靠地连接第三半导体层的表面。可重复地制造具有良好性能和高可靠性的半导体器件。

10. 发明授权

US4918107A Glutamate receptor inhibitor and insecticidal composition 失效
标题翻译：谷氨酸受体抑制剂和杀虫组合物
公开(公告)号：US4918107A
公开(公告)日：1990-04-17
申请号：US202491
申请日：1988-06-06
申请人： Terumi Nakajima , Nobufumi Kawai , Koichi Shudo , Tetsuo Shiba
发明人： Terumi Nakajima , Nobufumi Kawai , Koichi Shudo , Tetsuo Shiba
IPC分类号： A01N37/46 , C07C231/02 , C07C237/22
CPC分类号： A01N37/46 , C07C237/22
摘要： A compound of the formula ##STR1## wherein R' is hydrogen atom or an alkyl group, m is an integer of 1 to 3, p is 1 or 2, x is an integer of 2 to 6, and y is an integer of 1 to 3, or a salt thereof, which has glutamate receptor inhibitor activity, a process for preparing the same and an insecticidal composition containing the same are provided.
摘要翻译：式IMA的化合物，其中R'为氢原子或烷基，m为1〜3的整数，p为1或2，x为2〜6的整数，y为1的整数至3，或其盐，其具有谷氨酸受体抑制剂活性，其制备方法和含有它们的杀虫组合物。

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