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1. 发明申请

US20140200287A1 Reactive Dyes For Contact Lenses 有权
标题翻译：隐形眼镜用活性染料
公开(公告)号：US20140200287A1
公开(公告)日：2014-07-17
申请号：US14131915
申请日：2012-07-17
申请人： Yuan Xu , Charlie Chen , Charles A. Francis , Shane Mao , Hong Xue , Xining Zhang
发明人： Yuan Xu , Charlie Chen , Charles A. Francis , Shane Mao , Hong Xue , Xining Zhang
IPC分类号： C09B1/34 , G02B1/04 , C09B1/16
CPC分类号： C09B1/343 , C09B1/16 , C09B1/34 , C09B62/80 , C09B69/101 , G02B1/043 , C08L101/14 , C08L101/12
摘要： A method for preparing a polymerizable monomer-dye compound is provided in which a monomer, a reactive dye, and base are combined under substantially anhydrous reaction conditions to form the polymerizable monomer-dye compound, wherein the monomer comprises a pendant reactive group that covalently links to the reactive dye to form the monomer-dye compound.
摘要翻译：提供了一种制备可聚合单体 - 染料化合物的方法，其中单体，活性染料和碱在基本上无水的反应条件下组合以形成可聚合单体 - 染料化合物，其中单体包括共价连接与活性染料反应形成单体 - 染料化合物。

2. 发明授权

US08865929B2 Reactive dyes for contact lenses 有权
标题翻译：隐形眼镜用活性染料
公开(公告)号：US08865929B2
公开(公告)日：2014-10-21
申请号：US14131915
申请日：2012-07-17
申请人： Yuan Xu , Charlie Chen , Charles A. Francis , Shane Mao , Hong Xue , Xining Zhang
发明人： Yuan Xu , Charlie Chen , Charles A. Francis , Shane Mao , Hong Xue , Xining Zhang
IPC分类号： C09B62/465 , C09B1/34 , G02B1/04 , C09B62/80 , C09B69/10 , C09B1/16
CPC分类号： C09B1/343 , C09B1/16 , C09B1/34 , C09B62/80 , C09B69/101 , G02B1/043 , C08L101/14 , C08L101/12
摘要： A method for preparing a polymerizable monomer-dye compound is provided in which a monomer, a reactive dye, and base are combined under substantially anhydrous reaction conditions to form the polymerizable monomer-dye compound, wherein the monomer comprises a pendant reactive group that covalently links to the reactive dye to form the monomer-dye compound.
摘要翻译：提供了一种制备可聚合单体 - 染料化合物的方法，其中单体，活性染料和碱在基本上无水的反应条件下组合以形成可聚合单体 - 染料化合物，其中单体包括共价连接与活性染料反应形成单体 - 染料化合物。

3. 发明授权

US09296159B2 Silicone hydrogel contact lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US09296159B2
公开(公告)日：2016-03-29
申请号：US13983306
申请日：2012-02-23
申请人： Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
发明人： Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
IPC分类号： G02B1/04 , B29D11/00 , C08F290/06
CPC分类号： B29D11/00125 , B29D11/0025 , C08F290/068 , G02B1/043 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer, or at least one hydrophilic vinyl ether-containing monomer, or both, wherein, when the at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, and when the at least one hydrophilic vinyl ether-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：衍生自包含至少一种硅氧烷单体和至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体或至少一种亲水乙烯基醚的单体或两者的可聚合组合物的硅氧烷水凝胶隐形眼镜，其中当在在可聚合组合物中存在至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体，其存在量为1至20单位份重量，并且当至少一种亲水乙烯基醚单体存在于可聚合组合物的含量为1〜20单位重量份。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

4. 发明申请

US20140009735A1 Silicone Hydrogel Contact Lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US20140009735A1
公开(公告)日：2014-01-09
申请号：US13983306
申请日：2012-02-23
申请人： Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
发明人： Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
IPC分类号： G02B1/04 , B29D11/00
CPC分类号： B29D11/00125 , B29D11/0025 , C08F290/068 , G02B1/043 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer, or at least one hydrophilic vinyl ether-containing monomer, or both, wherein, when the at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, and when the at least one hydrophilic vinyl ether-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：衍生自包含至少一种硅氧烷单体和至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体或至少一种亲水乙烯基醚的单体或两者的可聚合组合物的硅氧烷水凝胶隐形眼镜，其中当在在可聚合组合物中存在至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体，其存在量为1至20单位份重量，并且当至少一种亲水乙烯基醚单体存在于可聚合组合物的含量为1〜20单位重量份。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

5. 发明授权

US08487058B2 Wettable silicone hydrogel contact lenses 有权
标题翻译：可湿性硅酮水凝胶隐形眼镜
公开(公告)号：US08487058B2
公开(公告)日：2013-07-16
申请号：US13404037
申请日：2012-02-24
申请人： Yuwen Liu , Charlie Chen , Charles A. Francis , Junhao Ge , Yuan Xu , Li Yao , Arthur Back , Ying Zheng
发明人： Yuwen Liu , Charlie Chen , Charles A. Francis , Junhao Ge , Yuan Xu , Li Yao , Arthur Back , Ying Zheng
IPC分类号： C08F230/06 , C08F290/06 , G02B1/04
CPC分类号： G02C7/04 , B65B5/04 , G02B1/043 , C08L83/12 , C08L33/08 , C08L33/10
摘要： Ophthalmically acceptably wettable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer. The lenses have ophthalmically acceptably wettable lens surfaces when fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：描述了眼科可接受的可湿性硅氧水凝胶隐形眼镜。透镜衍生自包含第一硅氧烷单体的可聚合组合物。当完全水合时，镜片具有眼科可接受的可润湿透镜表面。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

6. 发明申请

US20120220743A1 Dimensionally Stable Silicone Hydrogel Contact Lenses 有权
标题翻译：尺寸稳定的硅胶水凝胶隐形眼镜
公开(公告)号：US20120220743A1
公开(公告)日：2012-08-30
申请号：US13404034
申请日：2012-02-24
申请人： Charles A. Francis , Ying Zheng , Yuan Xu , Li Yao , Arthur Back , Ye Hong , Charlie Chen
发明人： Charles A. Francis , Ying Zheng , Yuan Xu , Li Yao , Arthur Back , Ye Hong , Charlie Chen
IPC分类号： C08F230/08
CPC分类号： C08F230/08 , C08F222/1006
摘要： Dimensionally stable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer represented by formula (2): wherein R1 of formula (2) is selected from either hydrogen atom or a methyl group; R2 of formula (2) is selected from either of hydrogen atom or a hydrocarbon group having 1 to 4 carbon atoms; m of formula (2) represents an integer of from 0 to 10; n of formula (2) represents an integer of from 4 to 100; a and b represent integers of 1 or more; a+b is equal to 20-500; b/(a+b) is equal to 0.01-0.22; the configuration of siloxane units includes a random configuration, the second siloxane monomer having a number average molecular weight of at least 3,000 daltons that is present in the polymerizable composition in an amount such that ratio of the first siloxane monomer to the second siloxane monomer is at least 2:1 based on unit parts by weight. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：描述了尺寸稳定的硅酮水凝胶隐形眼镜。透镜衍生自包含由式（1）表示的第一硅氧烷单体的可聚合组合物：其中式（1）的m表示3至10的一个整数，式（1）的n表示1至10的整数，R 1 式（1）的烷基是碳原子数为1〜4的烷基，式（1）的各R 2独立地为氢原子或甲基。透镜还包括衍生自由式（2）表示的第二硅氧烷单体的单元：其中式（2）的R 1选自氢原子或甲基; 式（2）的R2选自氢原子或碳原子数为1〜4的烃基; 式（2）的m表示0〜10的整数，式（2）的n表示4〜100的整数， a和b表示1以上的整数; a + b等于20-500; b /（a + b）等于0.01-0.22; 硅氧烷单元的构型包括随机构型，第二硅氧烷单体的数均分子量为至少3,000道尔顿，其存在于可聚合组合物中，其量使得第一硅氧烷单体与第二硅氧烷单体的比率在至少2：1，单位重量份。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

7. 发明授权

US09217813B2 Silicone hydrogel contact lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US09217813B2
公开(公告)日：2015-12-22
申请号：US13983307
申请日：2012-02-23
申请人： Yuwen Liu , Junhao Ge , Charlie Chen , Yuan Xu , Li Yao , Arthur Back , Charles A. Francis
发明人： Yuwen Liu , Junhao Ge , Charlie Chen , Yuan Xu , Li Yao , Arthur Back , Charles A. Francis
IPC分类号： G02B1/04 , B29D11/00 , G02C7/04 , C08L83/12
CPC分类号： G02B1/043 , B29D11/00125 , C08L83/12 , G02C7/04 , G02C7/049 , C08L101/14 , C08L83/04
摘要： Silicone hydrogel contact lenses are formed from the reaction product of a polymerizable composition comprising at least one acrylate-containing siloxane monomer, at least one hydrophilic vinyl-containing monomer, and at least one vinyl-containing cross-linking agent. The contact lenses have ophthalmically-acceptable ionoflux values and surface wettability, and can be manufactured without the use of volatile organic solvents.
摘要翻译：硅氧烷水凝胶隐形眼镜由包含至少一种含丙烯酸酯的硅氧烷单体，至少一种亲水性含乙烯基单体和至少一种含乙烯基交联剂的可聚合组合物的反应产物形成。隐形眼镜具有眼睛可接受的离子通量值和表面润湿性，并且可以在不使用挥发性有机溶剂的情况下制造。

8. 发明授权

US09057822B2 Silicone hydrogel contact lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US09057822B2
公开(公告)日：2015-06-16
申请号：US13983774
申请日：2012-02-23
申请人： Yuwen Liu , Ye Hong , Junhao Ge , Yuan Xu , Charlie Chen , Charles A. Francis , Li Yao , Arthur Back
发明人： Yuwen Liu , Ye Hong , Junhao Ge , Yuan Xu , Charlie Chen , Charles A. Francis , Li Yao , Arthur Back
IPC分类号： G02B1/04 , C08F283/12 , C08F236/20 , C08F226/00 , C08F283/06 , C08L51/08 , C08J11/02
CPC分类号： G02B1/043 , C08F226/00 , C08F236/20 , C08F283/065 , C08F283/126 , C08J11/02 , C08L51/085 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including a first siloxane monomer represented by formula (3): wherein m of formula (3) represents one integer from 3 to 10, n of formula (3) represents one integer from 1 to 10, R1 of formula (3) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (3) is independently either a hydrogen atom or a methyl group; and at least one vinyl ether-containing cross-linking agent are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described. In one example, the batches of silicone hydrogel contact lenses are dimensionally stable, and the method of making is a method of making dimensionally stable silicone hydrogel contact lenses.
摘要翻译：衍生自包含由式（3）表示的第一硅氧烷单体的可聚合组合物的聚合性组合物的硅氧水凝胶隐形眼镜：式（3）的m表示3〜10的整数，式（3）的n表示1〜 10，式（3）的R 1为碳原子数1〜4的烷基，式（3）的各R 2独立地为氢原子或甲基。和至少一种含乙烯基醚的交联剂。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。在一个示例中，硅胶水凝胶隐形眼镜的批次是尺寸稳定的，并且制造方法是制备尺寸稳定的硅酮水凝胶隐形眼镜的方法。

9. 发明申请

US20140016086A1 Silicone Hydrogel Contact Lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US20140016086A1
公开(公告)日：2014-01-16
申请号：US13983774
申请日：2012-02-23
申请人： Yuwen Liu , Ye Hong , Junhao Ge , Yuan Xu , Charlie Chen , Charles A. Francis , Li Yao , Arthur Back
发明人： Yuwen Liu , Ye Hong , Junhao Ge , Yuan Xu , Charlie Chen , Charles A. Francis , Li Yao , Arthur Back
IPC分类号： G02C7/04
CPC分类号： G02B1/043 , C08F226/00 , C08F236/20 , C08F283/065 , C08F283/126 , C08J11/02 , C08L51/085 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including a first siloxane monomer represented by formula (3): wherein m of formula (3) represents one integer from 3 to 10, n of formula (3) represents one integer from 1 to 10, R1 of formula (3) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (3) is independently either a hydrogen atom or a methyl group; and at least one vinyl ether-containing cross-linking agent are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described. In one example, the batches of silicone hydrogel contact lenses are dimensionally stable, and the method of making is a method of making dimensionally stable silicone hydrogel contact lenses.
摘要翻译：衍生自包含由式（3）表示的第一硅氧烷单体的可聚合组合物的聚合性组合物的硅氧水凝胶隐形眼镜：式（3）的m表示3〜10的整数，式（3）的n表示1〜 10，式（3）的R 1为碳原子数1〜4的烷基，式（3）的各R 2独立地为氢原子或甲基。和至少一种含乙烯基醚的交联剂。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。在一个示例中，硅胶水凝胶隐形眼镜的批次是尺寸稳定的，并且制造方法是制备尺寸稳定的硅酮水凝胶隐形眼镜的方法。

10. 发明申请

US20140049746A1 Silicone Hydrogel Contact Lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US20140049746A1
公开(公告)日：2014-02-20
申请号：US13983307
申请日：2012-02-23
申请人： Yuwen Liu , Junhao Ge , Charlie Chen , Yuan Xu , Li Yao , Arthur Back , Charles A. Francis
发明人： Yuwen Liu , Junhao Ge , Charlie Chen , Yuan Xu , Li Yao , Arthur Back , Charles A. Francis
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , B29D11/00125 , C08L83/12 , G02C7/04 , G02C7/049 , C08L101/14 , C08L83/04
摘要： Silicone hydrogel contact lenses are formed from the reaction product of a polymerizable composition comprising at least one acrylate-containing siloxane monomer, at least one hydrophilic vinyl-containing monomer, and at least one vinyl-containing cross-linking agent. The contact lenses have ophthalmically-acceptable ionoflux values and surface wettability, and can be manufactured without the use of volatile organic solvents.
摘要翻译：硅氧烷水凝胶隐形眼镜由包含至少一种含丙烯酸酯的硅氧烷单体，至少一种亲水性含乙烯基单体和至少一种含乙烯基交联剂的可聚合组合物的反应产物形成。隐形眼镜具有眼睛可接受的离子通量值和表面润湿性，并且可以在不使用挥发性有机溶剂的情况下制造。

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