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1. 发明申请

US20140049746A1 Silicone Hydrogel Contact Lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US20140049746A1
公开(公告)日：2014-02-20
申请号：US13983307
申请日：2012-02-23
申请人： Yuwen Liu , Junhao Ge , Charlie Chen , Yuan Xu , Li Yao , Arthur Back , Charles A. Francis
发明人： Yuwen Liu , Junhao Ge , Charlie Chen , Yuan Xu , Li Yao , Arthur Back , Charles A. Francis
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , B29D11/00125 , C08L83/12 , G02C7/04 , G02C7/049 , C08L101/14 , C08L83/04
摘要： Silicone hydrogel contact lenses are formed from the reaction product of a polymerizable composition comprising at least one acrylate-containing siloxane monomer, at least one hydrophilic vinyl-containing monomer, and at least one vinyl-containing cross-linking agent. The contact lenses have ophthalmically-acceptable ionoflux values and surface wettability, and can be manufactured without the use of volatile organic solvents.
摘要翻译：硅氧烷水凝胶隐形眼镜由包含至少一种含丙烯酸酯的硅氧烷单体，至少一种亲水性含乙烯基单体和至少一种含乙烯基交联剂的可聚合组合物的反应产物形成。隐形眼镜具有眼睛可接受的离子通量值和表面润湿性，并且可以在不使用挥发性有机溶剂的情况下制造。

2. 发明申请

US20120220744A1 Wettable Silicone Hydrogel Contact Lenses 有权
标题翻译：可湿性硅胶水凝胶隐形眼镜
公开(公告)号：US20120220744A1
公开(公告)日：2012-08-30
申请号：US13404037
申请日：2012-02-24
申请人： Yuwen Liu , Charlie Chen , Charles A. Francis , Junhao Ge , Yuan Xu , Li Yao , Arthur Back , Ying Zheng
发明人： Yuwen Liu , Charlie Chen , Charles A. Francis , Junhao Ge , Yuan Xu , Li Yao , Arthur Back , Ying Zheng
IPC分类号： C08F230/08
CPC分类号： G02C7/04 , B65B5/04 , G02B1/043 , C08L83/12 , C08L33/08 , C08L33/10
摘要： Ophthalmically acceptably wettable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer. The lenses have ophthalmically acceptably wettable lens surfaces when fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：描述了眼科可接受的可湿性硅氧水凝胶隐形眼镜。透镜衍生自包含第一硅氧烷单体的可聚合组合物。当完全水合时，镜片具有眼科可接受的可润湿透镜表面。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

3. 发明授权

US09217813B2 Silicone hydrogel contact lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US09217813B2
公开(公告)日：2015-12-22
申请号：US13983307
申请日：2012-02-23
申请人： Yuwen Liu , Junhao Ge , Charlie Chen , Yuan Xu , Li Yao , Arthur Back , Charles A. Francis
发明人： Yuwen Liu , Junhao Ge , Charlie Chen , Yuan Xu , Li Yao , Arthur Back , Charles A. Francis
IPC分类号： G02B1/04 , B29D11/00 , G02C7/04 , C08L83/12
CPC分类号： G02B1/043 , B29D11/00125 , C08L83/12 , G02C7/04 , G02C7/049 , C08L101/14 , C08L83/04
摘要： Silicone hydrogel contact lenses are formed from the reaction product of a polymerizable composition comprising at least one acrylate-containing siloxane monomer, at least one hydrophilic vinyl-containing monomer, and at least one vinyl-containing cross-linking agent. The contact lenses have ophthalmically-acceptable ionoflux values and surface wettability, and can be manufactured without the use of volatile organic solvents.
摘要翻译：硅氧烷水凝胶隐形眼镜由包含至少一种含丙烯酸酯的硅氧烷单体，至少一种亲水性含乙烯基单体和至少一种含乙烯基交联剂的可聚合组合物的反应产物形成。隐形眼镜具有眼睛可接受的离子通量值和表面润湿性，并且可以在不使用挥发性有机溶剂的情况下制造。

4. 发明授权

US09296159B2 Silicone hydrogel contact lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US09296159B2
公开(公告)日：2016-03-29
申请号：US13983306
申请日：2012-02-23
申请人： Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
发明人： Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
IPC分类号： G02B1/04 , B29D11/00 , C08F290/06
CPC分类号： B29D11/00125 , B29D11/0025 , C08F290/068 , G02B1/043 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer, or at least one hydrophilic vinyl ether-containing monomer, or both, wherein, when the at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, and when the at least one hydrophilic vinyl ether-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：衍生自包含至少一种硅氧烷单体和至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体或至少一种亲水乙烯基醚的单体或两者的可聚合组合物的硅氧烷水凝胶隐形眼镜，其中当在在可聚合组合物中存在至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体，其存在量为1至20单位份重量，并且当至少一种亲水乙烯基醚单体存在于可聚合组合物的含量为1〜20单位重量份。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

5. 发明申请

US20140009735A1 Silicone Hydrogel Contact Lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US20140009735A1
公开(公告)日：2014-01-09
申请号：US13983306
申请日：2012-02-23
申请人： Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
发明人： Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
IPC分类号： G02B1/04 , B29D11/00
CPC分类号： B29D11/00125 , B29D11/0025 , C08F290/068 , G02B1/043 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer, or at least one hydrophilic vinyl ether-containing monomer, or both, wherein, when the at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, and when the at least one hydrophilic vinyl ether-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：衍生自包含至少一种硅氧烷单体和至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体或至少一种亲水乙烯基醚的单体或两者的可聚合组合物的硅氧烷水凝胶隐形眼镜，其中当在在可聚合组合物中存在至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体，其存在量为1至20单位份重量，并且当至少一种亲水乙烯基醚单体存在于可聚合组合物的含量为1〜20单位重量份。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

6. 发明授权

US08487058B2 Wettable silicone hydrogel contact lenses 有权
标题翻译：可湿性硅酮水凝胶隐形眼镜
公开(公告)号：US08487058B2
公开(公告)日：2013-07-16
申请号：US13404037
申请日：2012-02-24
申请人： Yuwen Liu , Charlie Chen , Charles A. Francis , Junhao Ge , Yuan Xu , Li Yao , Arthur Back , Ying Zheng
发明人： Yuwen Liu , Charlie Chen , Charles A. Francis , Junhao Ge , Yuan Xu , Li Yao , Arthur Back , Ying Zheng
IPC分类号： C08F230/06 , C08F290/06 , G02B1/04
CPC分类号： G02C7/04 , B65B5/04 , G02B1/043 , C08L83/12 , C08L33/08 , C08L33/10
摘要： Ophthalmically acceptably wettable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer. The lenses have ophthalmically acceptably wettable lens surfaces when fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：描述了眼科可接受的可湿性硅氧水凝胶隐形眼镜。透镜衍生自包含第一硅氧烷单体的可聚合组合物。当完全水合时，镜片具有眼科可接受的可润湿透镜表面。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

7. 发明授权

US09057822B2 Silicone hydrogel contact lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US09057822B2
公开(公告)日：2015-06-16
申请号：US13983774
申请日：2012-02-23
申请人： Yuwen Liu , Ye Hong , Junhao Ge , Yuan Xu , Charlie Chen , Charles A. Francis , Li Yao , Arthur Back
发明人： Yuwen Liu , Ye Hong , Junhao Ge , Yuan Xu , Charlie Chen , Charles A. Francis , Li Yao , Arthur Back
IPC分类号： G02B1/04 , C08F283/12 , C08F236/20 , C08F226/00 , C08F283/06 , C08L51/08 , C08J11/02
CPC分类号： G02B1/043 , C08F226/00 , C08F236/20 , C08F283/065 , C08F283/126 , C08J11/02 , C08L51/085 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including a first siloxane monomer represented by formula (3): wherein m of formula (3) represents one integer from 3 to 10, n of formula (3) represents one integer from 1 to 10, R1 of formula (3) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (3) is independently either a hydrogen atom or a methyl group; and at least one vinyl ether-containing cross-linking agent are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described. In one example, the batches of silicone hydrogel contact lenses are dimensionally stable, and the method of making is a method of making dimensionally stable silicone hydrogel contact lenses.
摘要翻译：衍生自包含由式（3）表示的第一硅氧烷单体的可聚合组合物的聚合性组合物的硅氧水凝胶隐形眼镜：式（3）的m表示3〜10的整数，式（3）的n表示1〜 10，式（3）的R 1为碳原子数1〜4的烷基，式（3）的各R 2独立地为氢原子或甲基。和至少一种含乙烯基醚的交联剂。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。在一个示例中，硅胶水凝胶隐形眼镜的批次是尺寸稳定的，并且制造方法是制备尺寸稳定的硅酮水凝胶隐形眼镜的方法。

8. 发明申请

US20140016086A1 Silicone Hydrogel Contact Lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US20140016086A1
公开(公告)日：2014-01-16
申请号：US13983774
申请日：2012-02-23
申请人： Yuwen Liu , Ye Hong , Junhao Ge , Yuan Xu , Charlie Chen , Charles A. Francis , Li Yao , Arthur Back
发明人： Yuwen Liu , Ye Hong , Junhao Ge , Yuan Xu , Charlie Chen , Charles A. Francis , Li Yao , Arthur Back
IPC分类号： G02C7/04
CPC分类号： G02B1/043 , C08F226/00 , C08F236/20 , C08F283/065 , C08F283/126 , C08J11/02 , C08L51/085 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including a first siloxane monomer represented by formula (3): wherein m of formula (3) represents one integer from 3 to 10, n of formula (3) represents one integer from 1 to 10, R1 of formula (3) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (3) is independently either a hydrogen atom or a methyl group; and at least one vinyl ether-containing cross-linking agent are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described. In one example, the batches of silicone hydrogel contact lenses are dimensionally stable, and the method of making is a method of making dimensionally stable silicone hydrogel contact lenses.
摘要翻译：衍生自包含由式（3）表示的第一硅氧烷单体的可聚合组合物的聚合性组合物的硅氧水凝胶隐形眼镜：式（3）的m表示3〜10的整数，式（3）的n表示1〜 10，式（3）的R 1为碳原子数1〜4的烷基，式（3）的各R 2独立地为氢原子或甲基。和至少一种含乙烯基醚的交联剂。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。在一个示例中，硅胶水凝胶隐形眼镜的批次是尺寸稳定的，并且制造方法是制备尺寸稳定的硅酮水凝胶隐形眼镜的方法。

9. 发明授权

US09121998B2 Silicone hydrogel contact lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US09121998B2
公开(公告)日：2015-09-01
申请号：US13983578
申请日：2012-02-23
申请人： Charlie Chen , Yuwen Liu , Yuan Xu , Ying Zheng , Junhao Ge , Li Yao , Arthur Back
发明人： Charlie Chen , Yuwen Liu , Yuan Xu , Ying Zheng , Junhao Ge , Li Yao , Arthur Back
IPC分类号： C08L101/14 , C08L83/04 , G02C7/04 , G02B1/04
CPC分类号： G02B1/043 , C08L51/085 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including 30-60 unit parts by weight of a hydrophilic monomer(s) having one N-vinyl group, 10 to 50 unit parts by weight of 2-hydroxyethyl methacrylate (HEMA), and a first siloxane monomer component comprising a siloxane monomer of formula (1) as described herein or a siloxane monomer of formula (2) as described herein or a siloxane monomer of formula (3) as described herein or any combination thereof, where the total amount of siloxane monomer(s) present in the polymerizable composition is from 15 to 40 unit parts by weight. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：描述了硅酮水凝胶隐形眼镜。透镜衍生自可聚合组合物，其包含30-60单位重量份的具有一个N-乙烯基的亲水性单体，10-50单位重量份的甲基丙烯酸2-羟乙酯（HEMA）和第一个硅氧烷单体组分，其包含本文所述的式（1）的硅氧烷单体或本文所述的式（2）的硅氧烷单体或本文所述的式（3）的硅氧烷单体或其任何组合，其中硅氧烷单体的总量存在于聚合性组合物中的重量比为15〜40单位份。还描述了硅胶水凝胶隐形眼镜的批次和制备硅酮水凝胶隐形眼镜的方法。

10. 发明申请

US20140024738A1 Silicone Hydrogel Contact Lenses 有权
标题翻译：硅胶水凝胶隐形眼镜
公开(公告)号：US20140024738A1
公开(公告)日：2014-01-23
申请号：US13983578
申请日：2012-02-23
申请人： Charlie Chen , Yuwen Liu , Yuan Xu , Ying Zheng , Junhao Ge , Li Yao , Arthur Back
发明人： Charlie Chen , Yuwen Liu , Yuan Xu , Ying Zheng , Junhao Ge , Li Yao , Arthur Back
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , C08L51/085 , C08L83/04 , C08L101/14
摘要： Silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including 30-60 unit parts by weight of a hydrophilic monomer(s) having one N-vinyl group, 10 to 50 unit parts by weight of 2-hydroxyethyl methacrylate (HEMA), and a first siloxane monomer component comprising a siloxane monomer of formula (1) as described herein or a siloxane monomer of formula (2) as described herein or a siloxane monomer of formula (3) as described herein or any combination thereof, where the total amount of siloxane monomer(s) present in the polymerizable composition is from 15 to 40 unit parts by weight. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
摘要翻译：描述了硅酮水凝胶隐形眼镜。透镜衍生自可聚合组合物，其包含30-60单位重量份的具有一个N-乙烯基的亲水性单体，10-50单位重量份的甲基丙烯酸2-羟乙酯（HEMA）和第一个硅氧烷单体组分，其包含本文所述的式（1）的硅氧烷单体或本文所述的式（2）的硅氧烷单体或本文所述的式（3）的硅氧烷单体或其任何组合，其中硅氧烷单体的总量存在于聚合性组合物中的重量比为15〜40单位份。还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

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