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1. 发明授权

US09839581B2 Preassembled medicine mixer 有权
公开(公告)号：US09839581B2
公开(公告)日：2017-12-12
申请号：US14415605
申请日：2012-08-02
申请人： Yu Qiu , Ke Li , Yuan Yuan , Hongyu Li , Yeli Huang
发明人： Yu Qiu , Ke Li , Yuan Yuan , Hongyu Li , Yeli Huang
IPC分类号： A61J1/20 , A61J1/10 , A61J1/14 , A61J1/16
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1406 , A61J1/1462 , A61J1/16 , A61J1/201 , A61J1/2013 , A61J1/2065
摘要： A preassembled medicine mixer comprises a rotary sleeve (4), a guide sleeve I (3), a guide sleeve II (6), a guide part, a dosing barrel (1), and a dosing double needle (2). The guide sleeve I (3) extends into the guide sleeve II (6) and is connected to the rotary sleeve (4). A guide groove (8) is provided on the side wall of the guide sleeve I (3), and two ends of the guide groove (8) are extended by a distance towards opposite directions. A guide spiral groove (7) is provided on an inner wall of the guide sleeve II (6). The guide part is disposed in the guide sleeve I (3) and has a guide block (9) at the outer side thereof. The guide block (9) penetrates through the guide groove (8) and extends into the guide spiral groove (7). In use, the rotary sleeve (4) is rotated to drive the guide part to rapidly move downwards and push a medicine container (17); an upper needle tip of the dosing double needle (2) pierces a sealing plug on the medicine container (17), and a lower needle tip pierces a diaphragm (23) in an interface (22), so that the medicine container (17) is instantly communicated with an infusion container (14), thereby implementing sterile closeness during the entire process of transportation, storage, butt joint, medicine mixing, and infusion.

2. 发明授权

US09775778B2 Integrated medicine mixing interface 有权
公开(公告)号：US09775778B2
公开(公告)日：2017-10-03
申请号：US14415131
申请日：2012-08-02
申请人： Yu Qiu , Ke Li , Yuan Yuan , Hongyu Li , Bing Zhou , Liuying Zhao
发明人： Yu Qiu , Ke Li , Yuan Yuan , Hongyu Li , Bing Zhou , Liuying Zhao
IPC分类号： A61B19/00 , A61J1/20 , A61J1/10 , A61J1/14 , B01F13/00
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1481 , A61J1/2013 , A61J1/2051 , A61J1/2055 , B01F13/0023 , B01F2215/0032
摘要： An integrated medicine mixing interface comprising a medicine mixing mouth (1), hard double interfaces (2) and a medicine feed needle (3). The hard double interfaces (2) comprise a base (21), a medicine mixing interface (22) and an infusion interface (23). The medicine mixing mouth (1) and the medicine mixing interface (22) are integrated. When using the integrated medicine mixing interface, it is only necessary to weld the base (21) to the bag body of a soft infusion bag (11) and integrate the medicine mixing mouth (1) with the medicine mixing interface on the hard double interfaces (2) without adopting a hose connection and an easily folding handle, which not only reduces hose installation location, but also avoids welding leakage brought about by hose welding defects. Moreover, the structure is simple and the costs are low.

3. 发明申请

US20150202120A1 INTEGRATED MEDICINE MIXING INTERFACE 有权
标题翻译：综合医药混合界面
公开(公告)号：US20150202120A1
公开(公告)日：2015-07-23
申请号：US14415131
申请日：2012-08-02
申请人： Yu Qiu , Ke Li , Yuan Yuan , Hongyu Li , Bing Zhou , Liuying Zhao
发明人： Yu Qiu , Ke Li , Yuan Yuan , Hongyu Li , Bing Zhou , Liuying Zhao
IPC分类号： A61J1/20 , A61J1/10 , B01F13/00
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1481 , A61J1/2013 , A61J1/2051 , A61J1/2055 , B01F13/0023 , B01F2215/0032
摘要： An integrated medicine mixing interface comprising a medicine mixing mouth (1), hard double interfaces (2) and a medicine feed needle (3). The hard double interfaces (2) comprise a base (21), a medicine mixing interface (22) and an infusion interface (23). The medicine mixing mouth (1) and the medicine mixing interface (22) are integrated. When using the integrated medicine mixing interface, it is only necessary to weld the base (21) to the bag body of a soft infusion bag (11) and integrate the medicine mixing mouth (1) with the medicine mixing interface on the hard double interfaces (2) without adopting a hose connection and an easily folding handle, which not only reduces hose installation location, but also avoids welding leakage brought about by hose welding defects. Moreover, the structure is simple and the costs are low.
摘要翻译：一种综合医药混合界面，包括药物混合口（1），硬双界面（2）和药物进料针（3）。硬双界面（2）包括基部（21），药物混合界面（22）和输注界面（23）。药物混合口（1）和药物混合界面（22）被集成。当使用集成药物混合界面时，仅需要将基底（21）焊接到软质输液袋（11）的袋体上，并将药物混合口（1）与药物混合界面结合在硬双界面（2）不采用软管连接和易折叠手柄，不仅可以减少软管安装位置，还可以避免软管焊接缺陷引起的焊接泄漏。此外，结构简单，成本低廉。

4. 发明申请

US20150157536A1 DOSER HAVING TWO NEEDLES 审中-公开
标题翻译：具有两个针的药剂
公开(公告)号：US20150157536A1
公开(公告)日：2015-06-11
申请号：US14415604
申请日：2012-08-02
申请人： Yu Qiu , Ke Li , Yuan Yuan , Hongyu Li
发明人： Yu Qiu , Ke Li , Yuan Yuan , Hongyu Li
IPC分类号： A61J1/20 , A61J1/14
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2013 , A61J1/2055
摘要： A doser having two needles. The two needles consist of a needle seat (1), an upper needle (2), and a lower needle (3). The upper needle (2) and the lower needle (3) are arranged at two sides of the needle seat (1), and the upper needle (2) and the lower needle (3) both have a hollow structure and are in communication with each other. A medicine mixing body (4) of a cup structure is formed through extension in the direction along the edge of the needle seat (1) toward the upper needle (2). When the doser having two needle is used, it is only required that the upper needle (1) penetrates through a sealing plug of a medicine container and the lower needle (3) simultaneously penetrates through a sealing plug inside a sealing cover on a transfusion container, and by squeezing the transfusion container, medicine in the medicine container can be mixed with a solution in the transfusion container, which makes the medicine mixing operation simpler and more time saving.
摘要翻译：具有两个针头的加药器两针由针座（1），上针（2）和下针（3）组成。上针（2）和下针（3）布置在针座（1）的两侧，上针（2）和下针（3）都具有中空结构，并与彼此。通过沿着针座（1）的边缘方向朝向上针（2）延伸形成杯结构的药物混合体（4）。当使用具有两个针的加料器时，仅需要上针（1）穿过药物容器的密封塞，并且下针（3）同时穿过输液容器的密封盖内的密封塞，通过挤压输液容器，可以将药剂容器中的药物与输液容器中的溶液混合，使得药物混合操作更简单，更节省时间。

5. 发明申请

US20150174006A1 PREASSEMBLED MEDICINE MIXER 有权
标题翻译：预先配制的医药混合器
公开(公告)号：US20150174006A1
公开(公告)日：2015-06-25
申请号：US14415605
申请日：2012-08-02
申请人： Yu Qiu , Ke Li , Yuan Yuan , Hongyu Li , Yeli Huang
发明人： Yu Qiu , Ke Li , Yuan Yuan , Hongyu Li , Yeli Huang
IPC分类号： A61J1/20 , A61J1/14 , A61J1/16 , A61J1/10
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1406 , A61J1/1462 , A61J1/16 , A61J1/201 , A61J1/2013 , A61J1/2065
摘要： A preassembled medicine mixer comprises a rotary sleeve (4), a guide sleeve I (3), a guide sleeve II (6), a guide part, a dosing barrel (1), and a dosing double needle (2). The guide sleeve I (3) extends into the guide sleeve II (6) and is connected to the rotary sleeve (4). A guide groove (8) is provided on the side wall of the guide sleeve I (3), and two ends of the guide groove (8) are extended by a distance towards opposite directions. A guide spiral groove (7) is provided on an inner wall of the guide sleeve II (6). The guide part is disposed in the guide sleeve I (3) and has a guide block (9) at the outer side thereof. The guide block (9) penetrates through the guide groove (8) and extends into the guide spiral groove (7). In use, the rotary sleeve (4) is rotated to drive the guide part to rapidly move downwards and push a medicine container (17); an upper needle tip of the dosing double needle (2) pierces a sealing plug on the medicine container (17), and a lower needle tip pierces a diaphragm (23) in an interface (22), so that the medicine container (17) is instantly communicated with an infusion container (14), thereby implementing sterile closeness during the entire process of transportation, storage, butt joint, medicine mixing, and infusion.
摘要翻译：预组装的药物混合器包括旋转套筒（4），引导套筒I（3），导向套筒II（6），引导部件，计量筒（1）和计量双针（2）。引导套筒I（3）延伸到导向套筒II（6）中并连接到旋转套筒（4）上。引导槽（8）设置在导向套筒I（3）的侧壁上，并且引导槽（8）的两端向相反方向延伸一定距离。引导螺旋槽（7）设置在导向套筒II（6）的内壁上。引导部分设置在引导套筒I（3）中并且在其外侧具有引导块（9）。引导块（9）穿过引导槽（8）并延伸到引导螺旋槽（7）中。在使用中，旋转套筒（4）旋转以驱动引导部件快速向下移动并推动药物容器（17）; 给药双针（2）的上针尖刺穿药剂容器（17）上的密封塞，下针尖刺穿界面（22）中的隔膜（23），使药药容器（17）与输液容器（14）立即连通，从而在运输，储存，对接，药物混合和输液的整个过程中实现无菌接近。

6. 发明申请

US20170153135A1 ELECTROMAGNETIC FLOW SENSOR INTERFACE ALLOWING DIFFERENTIAL DC COUPLING 审中-公开
公开(公告)号：US20170153135A1
公开(公告)日：2017-06-01
申请号：US14975026
申请日：2015-12-18
申请人： Ke Li
发明人： Ke Li
IPC分类号： G01F1/60 , G01F1/58 , H03F3/45 , H03M1/12 , H03M1/66
摘要： An interface circuit to an electromagnetic flow sensor is described. In an example, it can provide a DC coupled signal path from the electromagnetic flow sensor to an analog-to-digital converter (ADC) circuit. Examples with differential and pseudo-differential signal paths are described. Examples providing DC offset or low frequency noise compensation or cancellation are described. High input impedance examples are described. Coil excitation circuits are described, such as can provide on-chip inductive isolation between signal inputs and signal outputs. A switched mode power supply can be used to actively manage a bias voltage of an H-Bridge, such as to boost the current provided by the H-Bridge to the sensor coil during select time periods, such as during phase shift time periods of the coil, which can help reduce or minimize transient noise during such time periods.

7. 发明授权

US08404871B2 Vapor-phase decarbonylation process 有权
标题翻译：气相脱羰工艺
公开(公告)号：US08404871B2
公开(公告)日：2013-03-26
申请号：US13124574
申请日：2009-12-08
申请人： Ke Li , Ronnie Ozer
发明人： Ke Li , Ronnie Ozer
IPC分类号： C07D307/36 , C07D307/48
CPC分类号： C07D307/36 , C07D307/46 , Y02P20/584
摘要： A process is provided for the synthesis of furan and related compounds by vapor phase decarbonylation of furfural and derivatives, using a palladium/alumina catalyst that has been promoted with an alkali carbonate. Catalyst lifetime is improved. The catalyst can be regenerated in situ by feeding a mixture of air and steam, with a composition of between about 2% and about 40% air, to the catalyst bed at a temperature between about 300° C. and about 500° C.
摘要翻译：提供了通过使用已经用碱金属碳酸盐促进的钯/氧化铝催化剂通过糠醛和衍生物的气相脱羰来合成呋喃和相关化合物的方法。催化剂寿命得到改善。催化剂可以通过在约300℃至约500℃之间的温度下将空气和蒸汽的混合物与约2％至约40％空气的组合物进料到催化剂床而在原位再生。

8. 发明申请

US20120121468A1 System For The Conversion Of Carbonaceous Feedstocks To A Gas Of A Specified Composition 审中-公开
标题翻译：将含碳原料转化成指定组合物的气体的系统
公开(公告)号：US20120121468A1
公开(公告)日：2012-05-17
申请号：US13235665
申请日：2011-09-19
申请人： Andreas Tsangaris , Kenneth C. Campbell , D. Michael Feasby , Ke Li
发明人： Andreas Tsangaris , Kenneth C. Campbell , D. Michael Feasby , Ke Li
IPC分类号： B01J7/00
CPC分类号： C10J3/16 , C10J3/005 , C10J3/18 , C10J3/463 , C10J3/721 , C10J3/723 , C10J2300/06 , C10J2300/093 , C10J2300/0959 , C10J2300/0973 , C10J2300/1238 , C10J2300/1618 , C10J2300/1621 , C10J2300/1646 , C10J2300/165 , C10J2300/1659 , C10J2300/1671 , C10J2300/1675 , C10J2300/1693 , C10J2300/1869 , C10J2300/1884 , F23G2204/201 , Y02E20/18 , Y02P20/129 , Y02P20/13
摘要： The present invention provides a carbonaceous feedstock gasification system with integrated control subsystem. The system generally comprises, in various combinations, a gasification reactor vessel (or converter) having one or more processing zones and one or more plasma heat sources, a solid residue handling subsystem, a gas quality conditioning subsystem, as well as an integrated control subsystem for managing the overall energetics of the conversion of the carbonaceous feedstock to energy, as well as maintaining all aspects of the gasification processes at an optimal set point. The gasification system may also optionally comprise a heat recovery subsystem and/or a product gas regulating subsystem.
摘要翻译：本发明提供一种具有综合控制子系统的碳质原料气化系统。该系统通常包括具有一个或多个处理区和一个或多个等离子体热源的气化反应器容器（或转换器），固体残余物处理子系统，气体质量调节子系统以及集成控制子系统用于管理碳质原料转化为能量的总体能量，以及将气化过程的所有方面保持在最佳设定点。气化系统还可以任选地包括热回收子系统和/或产品气体调节子系统。

9. 发明申请

US20120003321A1 Crosslinked Dextran Composite Magnetic Microparticles and Preparation Process and Using Method Thereof 审中-公开
标题翻译：交联葡聚糖复合磁性微粒及其制备方法及其使用方法
公开(公告)号：US20120003321A1
公开(公告)日：2012-01-05
申请号：US13142159
申请日：2008-12-29
申请人： Mingli Peng , Yanhong Liu , Yali Cui , Chao Chen , Ke Li
发明人： Mingli Peng , Yanhong Liu , Yali Cui , Chao Chen , Ke Li
IPC分类号： A61K9/14 , A61K31/513 , A61K31/337 , A61K31/7068 , A61K31/437 , A61K31/4375 , A61K31/704 , A61K38/14 , B82Y5/00
CPC分类号： A61K9/0009 , A61K9/0019 , A61K9/1611 , A61K9/1652 , H01F1/083
摘要： The present invention relates to crosslinked dextran magnetic composite microparticles and a preparation process and a using method thereof. The composite microparticles comprise magnetic nanoparticles and dextran with crosslinked structure, wherein the magnetic nanoparticles are dispersed in the dextran with crosslinked structure. The process for preparing the composite microparticles comprises: preparing a dextran solution; synthesizing dextran magnetic composite microparticles; and synthesizing the crosslinked dextran magnetic composite microparticles. The using method of composite microparticles comprises: preparing crosslinked dextran magnetic composite microparticles loaded with anti-cancer drug; and adding a sustained-releasing solution thereto.
摘要翻译：本发明涉及交联葡聚糖磁性复合微粒及其制备方法及其应用方法。复合微粒包括具有交联结构的磁性纳米颗粒和葡聚糖，其中磁性纳米颗粒分散在具有交联结构的葡聚糖中。制备复合微粒的方法包括：制备葡聚糖溶液; 合成葡聚糖磁复合微粒; 并合成交联的葡聚糖磁性复合微粒。复合微粒的使用方法包括：制备负载抗癌药物的交联葡聚糖磁复合微粒; 并向其中加入缓释溶液。

10. 发明申请

US20110313720A1 METHOD FOR IMPROVING FINITE ELEMENT ANALYSIS MODELING OF THREADED CONNECTIONS 审中-公开
标题翻译：改进螺纹连接有限元分析建模方法
公开(公告)号：US20110313720A1
公开(公告)日：2011-12-22
申请号：US13063111
申请日：2009-09-03
申请人： Ke Li , Srinand Karuppoor , Sepand Ossia
发明人： Ke Li , Srinand Karuppoor , Sepand Ossia
IPC分类号： G06F15/00
CPC分类号： E21B17/042
摘要： A method for improving finite element analysis of threaded connections includes selecting at least one thread parameter for a female connection and a corresponding male connection. In two dimensions a thread form is calculated for the female connection and the male connection based on the at least one parameter. In two dimensions a geometry is calculated of the female connection and the male connection based on the thread form. In two dimensions the female connection and the male connection are segmented into predefined areas. A finite element analysis mesh is calculated based on a predetermined number of nodes for each of the predefined areas and a selected number of mesh layers for each predefined area. The two dimensional female connection and male connection are assembled. The two dimensional mesh on the assembled connections is used as input to a finite element analysis of the threaded connection in three dimensions.
摘要翻译：用于改进螺纹连接的有限元分析的方法包括为母连接和相应的公连接选择至少一个螺纹参数。在两个维度上，基于至少一个参数来计算母连接和公连接的螺纹形式。在两个维度上，基于螺纹形式计算母连接和公连接的几何形状。在两个维度上，母连接和阳连接被分割成预定区域。基于用于每个预定义区域的预定数量的节点以及针对每个预定义区域的选定数目的网格层来计算有限元分析网格。组装了二维阴连接和阳连接。组装的连接上的二维网格用作三维螺纹连接的有限元分析的输入。

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