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    • 6. 发明授权
    • Process for producing a microcapsule
    • 微胶囊的制造方法
    • US4460722A
    • 1984-07-17
    • US351598
    • 1982-02-23
    • Yuriko IgarashiYoshio Okada
    • Yuriko IgarashiYoshio Okada
    • A61K9/50B01J13/18B01J13/20B41M5/165C08K5/07C08J3/10C08J3/16
    • B01J13/20A61K9/5089B41M5/165
    • Disclosed herein a process for producing a microcapsule having an excellent solvent-resistance and a thermal stability, and an extremely minute amount of unreacted formaldehyde, comprising the steps of dispersing a substance to be encapsulated into an aqueous solution containing a water-soluble cationic urea resin, at least one prepolymer selected from the group consisting of a melamine-formaldehyde prepolymer, a urea-formaldehyde prepolymer and a melamine-urea-formaldehyde prepolymer and an anionic surfactant and then, adding an acid-catalyst into the thus obtained aqueous dispersion thereby forming a wall membrane which encapsulates the dispersed microparticle of the substance to be encapsulated by polycondensing the prepolymer and the cationic urea resin followed by cross-linking while causing complex coacervation, and adding a monosaccharide into the aqueous dispersion while adjusting the pH of the aqueous dispersion with the addition of a hydroxide of an alkaline earth metal thereby removing the unreacted residual formaldehyde remaining in the aqueous dispersion.
    • 本文公开了具有优异的耐溶剂性,热稳定性和极少量未反应的甲醛的微胶囊的制造方法,其特征在于,包括将要包封的物质分散在含有水溶性阳离子脲树脂的水溶液中的步骤 ,至少一种选自三聚氰胺 - 甲醛预聚物,脲 - 甲醛预聚物和三聚氰胺 - 脲 - 甲醛预聚物和阴离子表面活性剂的预聚物,然后向所得水性分散体中加入酸催化剂,由此形成 通过使预聚物和阳离子脲树脂缩聚而封闭待包封物质的分散微粒的壁膜,随后进行交联同时引起复合凝聚,并且在调节水性分散体的pH的同时,向水性分散体中加入单糖,同时用 在那里加入碱土金属的氢氧化物 通过除去剩余在水分散体中的未反应的残余甲醛。