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1. 发明申请

US20080032926A1 Knockout Non-Human Animal 审中-公开
标题翻译：淘汰非人类动物
公开(公告)号：US20080032926A1
公开(公告)日：2008-02-07
申请号：US11659807
申请日：2005-08-09
申请人： Yoshikazu Naito , Kenji Oeda , Tokuo Sukata , Yoshifumi Inoue
发明人： Yoshikazu Naito , Kenji Oeda , Tokuo Sukata , Yoshifumi Inoue
IPC分类号： A61K38/00 , A01K67/00 , A61K48/00 , C12N15/00 , C12Q1/68 , G01N33/00 , C12N5/06 , C07K16/18 , A01K67/027
CPC分类号： C07K14/4702 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0325 , C12N15/8509 , C12N2517/02
摘要： The present invention relates to a knockout non-human animal whose genome comprises a disruption in at least one allele of the PHF3 gene, useful in developing drugs for diseases with the onset of atopic dermatitis or the like; a totipotent cell such as an ES cell which is essential to production of the above non-human animal; use thereof; and so on.
摘要翻译：本发明涉及一种敲除非人动物，其基因组包含PHF3基因的至少一个等位基因的破坏，可用于开发具有特应性皮炎等发作的疾病的药物; 全身细胞如ES细胞，其对于生产上述非人动物是必需的; 使用; 等等。

2. 发明申请

US20090284665A1 SOUND REPRODUCING APPARATUS AND AUDIOVISUAL SYSTEM 有权
标题翻译：声音再现设备和音响系统
公开(公告)号：US20090284665A1
公开(公告)日：2009-11-19
申请号：US12090997
申请日：2006-10-31
申请人： Masahiko Mizoguchi , Toshiki Murakami , Akifumi Sakamoto , Akihiro Mitani , Yoshifumi Inoue , Koichi Otsuka
发明人： Masahiko Mizoguchi , Toshiki Murakami , Akifumi Sakamoto , Akihiro Mitani , Yoshifumi Inoue , Koichi Otsuka
IPC分类号： H04N5/60
CPC分类号： H04N5/60 , H04N5/63 , H04N5/775 , H04N5/85 , H04N21/4122 , H04N21/43615 , H04N21/43635
摘要： In an audiovisual system in which a source device and a television are connected via an AV amplifier, even when the AV amplifier is placed in a “Power Supply Standby State”, video/audio signals outputted from the source device can be viewed/listened to on the television without changing the wiring connections between the devices.An AV amplifier (100) is provided with a data storing means (106) used for indicating a signal reproduction ability to a source device (200). During a “Power Supply Standby State” of the AV amplifier (100), the content of data that is saved in the data storing means (106) and indicates an audio signal reproduction ability is rewritten into data that indicates not the reproduction ability of the AV amplifier (100), but the signal reproduction ability of a television (300), thereby producing a state that is equivalent to a state in which the source device (200) and the television (300) are directly connected.
摘要翻译：在通过AV放大器连接源装置和电视机的音像系统中，即使AV放大器处于“电源待机状态”，从源装置输出的视频/音频信号也可以被观看/收听在电视上，而不改变设备之间的接线连接。 AV放大器（100）具有用于向源装置（200）指示信号再现能力的数据存储装置（106）。在AV放大器（100）的“电源待机状态”期间，保存在数据存储装置（106）中并且指示音频信号再现能力的数据的内容被重写为指示不是再现能力的数据 AV放大器（100），但是电视机（300）的信号再现能力，从而产生与源装置（200）和电视机（300）直接连接的状态相当的状态。

3. 发明申请

US20080153732A1 Cleaning Agent 失效
标题翻译：清洁剂
公开(公告)号：US20080153732A1
公开(公告)日：2008-06-26
申请号：US11793384
申请日：2005-12-14
申请人： Hisahiko Iwamoto , Yoshifumi Inoue , Masaaki Nakashima , Masafumi Kasai
发明人： Hisahiko Iwamoto , Yoshifumi Inoue , Masaaki Nakashima , Masafumi Kasai
IPC分类号： C11D7/26 , C07D309/00 , C07D313/00
CPC分类号： C11D7/267 , H01L51/0096 , H01L51/56
摘要： There is provided a cleaning agent comprising a lactone represented by the following formula (1): wherein R1 is an alkylene group having 3 to 6 carbon atoms.The cleaning agent is useful for cleaning an organic electroluminescence material, photosensitive resin, liquid crystal or wax.
摘要翻译：提供了包含由下式（1）表示的内酯的清洗剂：其中R 1是具有3至6个碳原子的亚烷基。清洁剂可用于清洁有机电致发光材料，感光性树脂，液晶或蜡。

4. 发明授权

US07045572B2 Organosilicon compound 有权
标题翻译：有机硅化合物
公开(公告)号：US07045572B2
公开(公告)日：2006-05-16
申请号：US11015024
申请日：2004-12-20
申请人： Toshiyuki Ozai , Hiroyasu Hara , Yoshifumi Inoue , Tomoyuki Goto
发明人： Toshiyuki Ozai , Hiroyasu Hara , Yoshifumi Inoue , Tomoyuki Goto
IPC分类号： C08G77/06
CPC分类号： C07F7/1804
摘要： An organosilicon compound represented by the following general formula (1): wherein R1 is a hydrogen atom, a phenyl group or a halogenated phenyl group; R2 is a hydrogen atom or a methyl group; R3's are each a substituted or unsubstituted monovalent hydrocarbon group having 1 to 10 carbon atoms; X is a hydrolyzable group; Z1 is —R4—, —R4O— or —R4(CH3)2SiO—, where R4 is a substituted or unsubstituted divalent hydrocarbon group having 1 to 10 carbon atoms; Z2 is an oxygen atom or a substituted or unsubstituted divalent hydrocarbon group having 1 to 10 carbon atoms; and m is 0, 1 or 2 and n is 0, 1 or 2. When incorporated in silicone compositions, the organosilicon compound acts as a cross-linking agent having well-balanced photopolymerizability and condensation curability.
摘要翻译：由以下通式（1）表示的有机硅化合物：其中R 1是氢原子，苯基或卤代苯基; R 2是氢原子或甲基; R 3各自为取代或未取代的碳原子数为1〜10的一价烃基; X是可水解基团; Z 1是-R 4 - ， - R 4 O-或-R 4（CH 3） 3 SiO 2，其中R 4是取代或未取代的具有1至10个碳原子的二价烃基; Z 2是氧原子或取代或未取代的碳原子数为1〜10的二价烃基; 并且m为0,1或2，n为0,1或2.当掺入有机硅组合物中时，有机硅化合物用作具有良好平衡光聚合性和缩合固化性的交联剂。

5. 发明授权

US06613440B2 Addition reaction curing type silicone rubber composition and making method 失效
公开(公告)号：US06613440B2
公开(公告)日：2003-09-02
申请号：US09905979
申请日：2001-07-17
申请人： Hiroyasu Hara , Hideki Sugahara , Yoshifumi Inoue , Takashi Aketa
发明人： Hiroyasu Hara , Hideki Sugahara , Yoshifumi Inoue , Takashi Aketa
IPC分类号： B32B2520
CPC分类号： C08K9/06 , C08G77/12 , C08G77/20 , C08L83/04 , Y10T428/31663 , C08L83/00 , C08L2666/54
摘要： An addition reaction curing type silicone rubber composition comprising (A) an alkenyl-containing diorganopolysiloxane, (B) an alkaline earth metal carbonate powder surface treated with a diorganopolysiloxane, (C) an organohydrogenpolysiloxane, and (D) a platinum group metal catalyst has improved storage stability in that it gives off little or no hydrogen gas during storage. The composition has improved adhesion and a good ability to protect electric or electronic parts from corrosion and finds typical use in the sealing of electric or electronic parts.

6. 发明授权

US5486567A Primer compositions 失效
标题翻译：底漆组合物
公开(公告)号：US5486567A
公开(公告)日：1996-01-23
申请号：US389196
申请日：1995-02-15
申请人： Masatoshi Arai , Yoshifumi Inoue , Toshiyuki Ozai
发明人： Masatoshi Arai , Yoshifumi Inoue , Toshiyuki Ozai
IPC分类号： C09D5/00 , C08J7/04 , C08K5/057 , C09D183/04 , C09J5/02 , C09J183/04 , C08L83/06
CPC分类号： C08J7/04 , C08K5/057 , C09D183/04 , C08J2383/04
摘要： This invention provides a primer composition comprising (A) a polyorganosiloxane resin containing at least 0.01 mole of hydroxyl groups per 100 g of the resin represented by the average composition formula: (R.sup.1).sub.a SiO.sub.(4-a)/2 wherein each R.sup.1 represents a substituted or unsubstituted monovalent hydrocarbon group, and a is a value of 0.4 to 1.8; (B) an alkoxytitanium or a partially hydrolyzed product thereof; (C) an acid; and (D) a solvent. The primer composition can strongly adhere a condensation type room temperature curable silicone elastomer to the surface of the coated metal formed by applying a fluororesin coating, an acrylic resin coating or the like to a metal.
摘要翻译：本发明提供了一种底漆组合物，其包含（A）每平均组成式：（R1）aSiO（4-a）/ 2表示的树脂含有至少0.01摩尔羟基的聚有机硅氧烷树脂，其中每个R 1表示取代或未取代的一价烃基，a为0.4〜1.8的值。（B）烷氧基钛或其部分水解产物; （C）酸; 和（D）溶剂。底漆组合物可以通过将氟树脂涂料，丙烯酸树脂涂料等施加到金属而形成的涂覆金属的表面上强烈地附着冷凝型室温可固化的硅氧烷弹性体。

7. 发明授权

US5244938A Room temperature curable organopolysiloxane composition 失效
标题翻译：室温可固化有机硅氧烷组合物
公开(公告)号：US5244938A
公开(公告)日：1993-09-14
申请号：US806342
申请日：1991-12-13
申请人： Masatoshi Arai , Yoshifumi Inoue , Yoshio Inoue
发明人： Masatoshi Arai , Yoshifumi Inoue , Yoshio Inoue
IPC分类号： C08K3/00 , C08K5/5419 , C08K5/57 , C08L83/04 , C08L83/06 , C08L83/08
CPC分类号： C08K5/5419 , C08L83/04 , C08L83/08 , C08G77/16 , C08G77/18 , C08G77/24 , Y10S528/901
摘要： The present invention is characterized by adding and mixing an organosilicon compound having alkoxy, groups and an ester linkage in the molecule represented by the following formula: ##STR1## in an amount of 1 to 20 parts by weight per 100 parts by weight of a trifluoropropylalkylpolysiloxane. Said organosilicon compound has a function as a storage stabilizer as well as a curing agent and, according to the present invention, an RTV fluorosilicone composition that has hitherto been difficult to be applied as an adhesive for electric and electronic parts has been made possible to be used in the particular field.

8. 发明授权

US5196477A Silcone compositions comprising organic compounds having the capabilities of coordination with metals 失效
标题翻译：包含具有与金属配位能力的有机化合物的丝素组合物
公开(公告)号：US5196477A
公开(公告)日：1993-03-23
申请号：US556496
申请日：1990-07-24
申请人： Masatoshi Arai , Yoshifumi Inoue , Kei Miyoshi
发明人： Masatoshi Arai , Yoshifumi Inoue , Kei Miyoshi
IPC分类号： C08K5/00 , C08K5/54 , C08K5/5419 , H01B3/46
CPC分类号： H01B3/46 , C08K5/0008 , C08K5/54 , C08K5/5419
摘要： Silicone compositions comprising an organopolysiloxane composition and an organic compound capable of coordination with metals are described. Since the organic compound is preferentially adsorbed on a metal surface, the composition is particularly suitable for use in electric or electronic parts to prevent contact failure. A more specific embodiment comprises a diorganopolysiloxane of the average unit formula, R.sub.a SiO.sub.(4-a)/2, wherein each R independently represents an unsubstituted or substituted monovalent hydrocarbon group, and a is a value of from 1.90 to 2.05, a filler, an alkoxysilane or its hydrolyzate, a silylation catalyst made of an organic silicon compound having at least one specific type of group, an organic tin compound, another organosilicon compound capable of reaction with an alcohol in order to stabilize the composition, and an organic compound capable of coordination with metals.
摘要翻译：描述了包含有机聚硅氧烷组合物和能与金属配位的有机化合物的硅酮组合物。由于有机化合物优先吸附在金属表面上，因此该组合物特别适用于电气或电子部件以防止接触不良。更具体的实施方案包括平均单元式的二有机聚硅氧烷，RaSiO（4-a）/ 2，其中每个R独立地表示未取代或取代的一价烃基，a为1.90至2.05的值，填料，烷氧基硅烷或其水解物，由具有至少一种特定类型基团的有机硅化合物制成的甲硅烷基化催化剂，有机锡化合物，能够与醇反应的另一种有机硅化合物以稳定组合物，以及能够与金属配合。

9. 发明授权

US07563843B2 Flame retardant silicone compositions 失效
标题翻译：阻燃硅酮组合物
公开(公告)号：US07563843B2
公开(公告)日：2009-07-21
申请号：US10438863
申请日：2003-05-16
申请人： Toshiyuki Ozai , Yoshifumi Inoue
发明人： Toshiyuki Ozai , Yoshifumi Inoue
IPC分类号： C08L83/04
CPC分类号： C08L83/04 , C08G77/12 , C08G77/20 , C08K5/544 , C08L83/00
摘要： An amino compound having a secondary amino group directly bonded to a phenyl group is modified by silylating the secondary amino group. When the silylated amino compound is compounded in a silicone composition comprising an organopolysiloxane containing at least two lower alkenyl groups, an organohydrogenpolysiloxane, and a platinum base curing catalyst, the composition is improved in flame retardance to the level of UL-94 V-0 without sacrificing the activity of the curing catalyst.
摘要翻译：具有与苯基直接键合的仲氨基的氨基化合物通过使仲氨基甲硅烷基化而被修饰。当甲硅烷基化的氨基化合物在包含含有至少两个低级链烯基的有机聚硅氧烷，有机氢聚硅氧烷和铂基固化催化剂的硅氧烷组合物中配混时，该组合物的阻燃性提高到UL-94V-0的水平，而没有牺牲固化催化剂的活性。

10. 发明授权

US5573929A Secretion vector for hirudin or hirudin analog production 失效
标题翻译：水蛭素或水蛭素类似物生产的分泌载体
公开(公告)号：US5573929A
公开(公告)日：1996-11-12
申请号：US348972
申请日：1994-11-28
申请人： Satoru Misawa , Hitoshi Matsuda , Yoshifumi Inoue , Hideyuki Furuya
发明人： Satoru Misawa , Hitoshi Matsuda , Yoshifumi Inoue , Hideyuki Furuya
IPC分类号： A61K38/00 , C07K14/815 , C12N1/21 , C12N9/16 , C12N15/10 , C12N15/12 , C12N15/15 , C12N15/55 , C12N15/62 , C12N15/70 , C12P21/06 , C12N1/20 , C12N15/63
CPC分类号： C07K14/815 , C12N15/10 , C12N9/16 , A61K38/00 , C07K2319/00 , C07K2319/02 , C07K2319/036 , C07K2319/33
摘要： Provided is a chimeric HV1/HV3 hirudin analog useful as an anti-coagulant, exhibiting higher anti-thrombin activity and less tendency to cause bleeding than hirudin HV1. Also provided are a method of producing hirudins and hirudin analogs, as well as other proteins, employing secretion vectors, and transformed microorganisms such as E. coli. Pharmaceutical compositions comprising various hirudins or the chimeric HV1/HV3 hirudin analog of the present invention and a pharmaceutically acceptable carrier are also disclosed.
摘要翻译：提供了一种嵌合型HV1 / HV3水蛭素类似物，可用作抗凝血剂，与水蛭素HV1相比表现出更高的抗凝血酶活性和较少的引起出血的倾向。还提供了生产水蛭素和水蛭素类似物的方法，以及使用分泌载体和转化的微生物如大肠杆菌的其它蛋白质的方法。还公开了包含本发明的各种水蛭素或嵌合HV1 / HV3水蛭素类似物的药物组合物和药学上可接受的载体。

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