专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5556636A Adhesive composition for medical use 失效
标题翻译：医用胶粘剂组合物
公开(公告)号：US5556636A
公开(公告)日：1996-09-17
申请号：US319085
申请日：1994-10-06
申请人： Yoshiaki Yano , Kazuyuki Takeo , Takayoshi Hidaka
发明人： Yoshiaki Yano , Kazuyuki Takeo , Takayoshi Hidaka
IPC分类号： A61K9/70 , A61K47/34 , A61L15/58 , A61F13/00
CPC分类号： A61K9/7076 , A61K47/34 , A61L15/58
摘要： The present invention is directed to a sticky composition for medical use comprising a tackifier resin and an oxyalkylene polymer having a silicon-containing group which can be crosslinked by forming a siloxane bond, wherein silicon atom thereof is bound with a hydroxyl group or hydrolytic group, and to a transdermal drug delivery preparation incorporating said sticky composition as a drug carrier. The sticky composition of the present invention possesses excellent adhesive properties, very low skin irritancy and good compatibility with the site of plastering and thus perform as a very safe and effective medical adhesive. The transdermal drug delivery preparation of the present invention offers excellent drug release from the sticky composition.
摘要翻译：本发明涉及用于医疗用途的粘性组合物，其包含增粘树脂和具有含硅基团的氧化烯聚合物，所述含硅基团可通过形成硅氧烷键而交联，其中硅原子与羟基或水解基团结合，以及掺入所述粘性组合物作为药物载体的透皮药物递送制剂。本发明的粘性组合物具有优异的粘合性能，非常低的皮肤刺激性和与抹灰部位的良好相容性，因此作为非常安全和有效的医用胶粘剂。本发明的透皮给药制剂从粘性组合物中提供优异的药物释放。

2. 发明授权

US5547683A Method for producing microgranulated particle 失效
标题翻译：微粒微粒生产方法
公开(公告)号：US5547683A
公开(公告)日：1996-08-20
申请号：US244375
申请日：1994-06-08
申请人： Yoshiaki Yano , Tamiji Fujimoto , Takayoshi Hidaka
发明人： Yoshiaki Yano , Tamiji Fujimoto , Takayoshi Hidaka
IPC分类号： A61K9/16 , B01J2/10 , B01J2/12 , B01J2/16 , A61K9/50 , B05D7/02 , B32B5/16
CPC分类号： B01J2/16 , A61K9/1694 , B01J2/10 , B01J2/12 , Y10T428/2982
摘要： The present invention relates to a method for producing a microgranulated particle having particle size of not more than 0.2 mm, wherein a fine powder with the average particle size of not more than 10 .mu.m, which is being agitated, tumbled or fluidized, is granulated, with a solution containing a binder alone or a binder and a surfactant being sprayed onto the surface thereof. The present invention allows to produce pharmaceutical preparations for poorly soluble and poorly absorbable drugs and preparations requiring a high content of the active ingredient. Also, it can provide an easy-to-handle powdery microgranulated particle in the field of food and fertilizers.
摘要翻译： PCT No.PCT / JP93 / 01442 Sec。 371日期：1994年6月8日 102（e）日期1994年6月8日PCT提交1993年10月6日PCT公布。出版物WO94 / 08709 日期：1994年04月28日本发明涉及一种粒径不大于0.2mm的微粒化微粒的制造方法，其特征在于，搅拌着平均粒径为10μm以下的细粉末，或流化的颗粒，其中包含单独的粘合剂或粘合剂和表面活性剂的溶液喷涂到其表面上。本发明允许制备难溶性和难吸收性药物和需要高含量活性成分的制剂的药物制剂。此外，它可以在食品和肥料领域提供易于处理的粉状微粒化颗粒。

3. 发明授权

US5298246A Stable pharmaceutical composition and method for its production 失效
标题翻译：稳定的药物组合物及其生产方法
公开(公告)号：US5298246A
公开(公告)日：1994-03-29
申请号：US815189
申请日：1991-12-31
申请人： Yoshiaki Yano , Shigeki Masuda , Takayoshi Hidaka
发明人： Yoshiaki Yano , Shigeki Masuda , Takayoshi Hidaka
IPC分类号： A61K9/127 , A61K37/48 , A61K37/00 , A61K37/12 , A61K37/22
CPC分类号： A61K9/1276
摘要： The present invention is directed to a stable pharmaceutical composition wherein the absorbability of a lipophilic drug which is insoluble or practically insoluble in water or another drug such as a bioactive peptide in oral administration has been improved to such extent that a high level of blood concentration can be retained, and to a method for producing such a stable pharmaceutical composition. The pharmaceutical composition of the present invention offers improvements in the absorbability, for example, a high level of blood concentration can be retained for a long time in oral administration because it is highly resistant to lipase. Also, the pharmaceutical composition is highly safe because the emulsifier used is derived from mammalian milk.
摘要翻译：本发明涉及一种稳定的药物组合物，其中口服给药中不溶于或几乎不溶于水或其它药物如生物活性肽的亲脂性药物的吸收性已经提高到高水平的血药浓度以及制备这种稳定的药物组合物的方法。本发明的药物组合物提供了吸收性的改善，例如，高浓度的血液浓度可长期保持在口服给药中，因为它高度耐脂肪酶。此外，药物组合物是高度安全的，因为所使用的乳化剂来自哺乳动物乳。

4. 发明授权

US5854368A Adjuvant for pharmaceutical preparations 失效
公开(公告)号：US5854368A
公开(公告)日：1998-12-29
申请号：US774492
申请日：1996-12-30
申请人： Koji Iritani , Tetsuya Kawasaki , Nobutaka Tani , Shigeki Masuda , Yoshiaki Yano
发明人： Koji Iritani , Tetsuya Kawasaki , Nobutaka Tani , Shigeki Masuda , Yoshiaki Yano
IPC分类号： A61K9/28 , A61K9/32 , C08G63/16 , C08G63/672 , C08G69/44 , C08G63/668
CPC分类号： C08G69/44 , A61K9/2853 , C08G63/16 , C08G63/672
摘要： A polyester represented by the following general formula (I) and a copolymer which comprises two structural units represented by the following general formulae (I') and (II). ##STR1## and a coating material for use in large intestine-selective drug release pharmaceutical preparations, which contains the above polyester and/or copolymer. The polyester and copolymer of the present invention contain a saccharide residue which is hydrolyzed and/or assimilated specifically in the large intestine, drugs contained in solid oral pharmaceutical administration pharmaceutical preparations coated with the coating material of the present invention are not decomposed or absorbed by digestive organs other than the large intestine, but instead are released selectively and therefore in a high concentration in the large intestine.

5. 发明授权

US5644012A Adjuvant for pharmaceutical preparations 失效
标题翻译：药物制剂佐剂
公开(公告)号：US5644012A
公开(公告)日：1997-07-01
申请号：US977100
申请日：1992-11-16
申请人： Koji Iritani , Tetsuya Kawasaki , Nobutaka Tani , Shigeki Masuda , Yoshiaki Yano
发明人： Koji Iritani , Tetsuya Kawasaki , Nobutaka Tani , Shigeki Masuda , Yoshiaki Yano
IPC分类号： A61K9/28 , A61K9/32 , C08G63/16 , C08G63/672 , C08G69/44 , C08G63/668
CPC分类号： C08G69/44 , A61K9/2853 , C08G63/16 , C08G63/672
摘要： A polyester represented by the following general formula (I) and a copolymer which comprises two structural units represented by the following general formulae (I') and (II). ##STR1## and a coating material for use in large intestine-selective drug release pharmaceutical preparations, which contains the above polyester and/or copolymer. The polyester and copolymer of the present invention contain a saccharide residue which is hydrolyzed and/or assimilated specifically in the large intestine, drugs contained in solid oral pharmaceutical administration pharmaceutical preparations coated with the coating material of the present invention are not decomposed or absorbed by digestive organs other than the large intestine, but instead are released selectively and therefore in a high concentration in the large intestine.
摘要翻译：由以下通式（I）表示的聚酯和包含由以下通式（I'）和（II）表示的两个结构单元的共聚物。含有上述聚酯和/或共聚物的大肠选择性药物释放药物制剂中使用的（I）。本发明的聚酯和共聚物含有在大肠中特异性水解和/或同化的糖残基，包被在本发明的涂料中的固体口服药物给药药物制剂中所含的药物不被消化物分解或吸收大肠以外的器官，而是选择性释放，因此在大肠中高浓度释放。

6. 发明授权

US4594300A Lead storage battery 失效
标题翻译：铅蓄电池
公开(公告)号：US4594300A
公开(公告)日：1986-06-10
申请号：US688496
申请日：1985-01-03
申请人： Yuji Morioka , Sigeru Yamasita , Yoshiaki Yano
发明人： Yuji Morioka , Sigeru Yamasita , Yoshiaki Yano
IPC分类号： H01M2/02 , H01M2/12 , H01M4/20 , H01M4/56 , H01M10/12
CPC分类号： H01M2/021 , H01M10/126 , H01M2/1229 , H01M4/20 , H01M4/56
摘要： A lead storage battery having electro-collecting boards of lead or lead alloys, and active material layers closely contacted with the electro-collecting boards. The active material layers are integrally formed with the electro-collecting boards by providing a mixture, in the form of slurry, of an active material powder and a liquid to the electro-collecting boards, and then drying the mixture.
摘要翻译：一种具有铅或铅合金的电集电板的铅蓄电池，以及与电集电板紧密接触的活性材料层。通过向电收集板提供活性材料粉末和液体的浆料形式的混合物，然后干燥混合物，将活性物质层与电收集板一体地形成。

7. 发明授权

US5576020A Adjuvant for pharmaceutical preparations 失效
标题翻译：药物制剂佐剂
公开(公告)号：US5576020A
公开(公告)日：1996-11-19
申请号：US421781
申请日：1995-04-14
申请人： Koji Iritani , Tetsuya Kawasaki , Nobutaka Tani , Shigeki Masuda , Yoshiaki Yano
发明人： Koji Iritani , Tetsuya Kawasaki , Nobutaka Tani , Shigeki Masuda , Yoshiaki Yano
IPC分类号： A61K9/28 , A61K9/32 , C08G63/16 , C08G63/672 , C08G69/44 , A61K47/30 , A61K47/26
CPC分类号： C08G69/44 , A61K9/2853 , C08G63/16 , C08G63/672
摘要： A polyester represented by the following general formula (I) and a copolymer which comprises two structural units represented by the following general formulae (I') and (II). ##STR1## and a coating material for use in large intestine-selective drug release pharmaceutical preparations, which contains the above polyester and/or copolymer. The polyester and copolymer of the present invention contain a saccharide residue which is hydrolyzed and/or assimilated specifically in the large intestine, drugs contained in solid oral pharmaceutical administration pharmaceutical preparations coated with the coating material of the present invention are not decomposed or absorbed by digestive organs other than the large intestine, but instead are released selectively and therefore in a high concentration in the large intestine.
摘要翻译：由以下通式（I）表示的聚酯和包含由以下通式（I'）和（II）表示的两个结构单元的共聚物。含有上述聚酯和/或共聚物的大肠选择性药物释放药物制剂中使用的（I）。本发明的聚酯和共聚物含有在大肠中特异性水解和/或同化的糖残基，包被在本发明的涂料中的固体口服药物给药药物制剂中所含的药物不被消化物分解或吸收大肠以外的器官，而是选择性释放，因此在大肠中高浓度释放。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式