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1. 发明申请

US20050240138A1 LINER FOR PATCH 有权
标题翻译：衬垫
公开(公告)号：US20050240138A1
公开(公告)日：2005-10-27
申请号：US10516184
申请日：2002-06-12
申请人： Yoshiaki Mori , Haruo Saito
发明人： Yoshiaki Mori , Haruo Saito
IPC分类号： A61K9/70 , A61F13/00
CPC分类号： A61F13/023 , A61F2013/00812 , A61F2013/00906 , A61F2013/0296 , A61K9/703
摘要： A liner for a patch used for covering the surface of a base agent layer of the patch is provided. In the liner of the invention, a tear line portion for dividing and peeling the liner off the base agent layer is provided at a predetermined location, and the thickness of the tear line portion is made thinner than a generally average thickness of the liner. Therefore, when the patch is about to be used, the liner can easily be torn at the tear line portion and peeled off the base agent layer.
摘要翻译：提供了用于覆盖贴剂的基剂层的表面的贴剂用衬垫。在本发明的衬垫中，在预定位置处设置用于将衬垫分离和剥离基底层的撕裂线部分，并且将撕裂线部分的厚度制成为比衬里的大致平均厚度更薄。因此，当即将使用贴片时，衬垫可以容易地撕裂在撕裂线部分并从基底层剥离。

2. 发明授权

US07164054B2 Liner for patch 有权
标题翻译：衬垫补丁
公开(公告)号：US07164054B2
公开(公告)日：2007-01-16
申请号：US10516184
申请日：2002-06-12
申请人： Yoshiaki Mori , Haruo Saito
发明人： Yoshiaki Mori , Haruo Saito
IPC分类号： A61F13/00 , A61F15/00
CPC分类号： A61F13/023 , A61F2013/00812 , A61F2013/00906 , A61F2013/0296 , A61K9/703
摘要： A liner for a patch used for covering the surface of a base agent layer of the patch may include a tear line portion for dividing and peeling the liner off the base agent layer is provided at a predetermined location. The thickness of the tear line portion may be made thinner than a generally average thickness of the liner. Therefore, when the patch is about to be used, the liner may easily be torn at the tear line portion and peeled off the base agent layer.
摘要翻译：用于覆盖贴片的基剂层的表面的贴剂的衬垫可以包括在预定位置处设置用于将衬里分离和剥离基底剂层的撕裂线部分。撕裂线部分的厚度可以制成比衬里的大致平均厚度更薄。因此，当即将使用贴片时，衬垫可能容易地在撕裂线部分处撕裂并从基底层剥离。

3. 发明授权

US07220309B2 Receptor linked protein tyrosine phosphatases 失效
标题翻译：受体连接蛋白酪氨酸磷酸酶
公开(公告)号：US07220309B2
公开(公告)日：2007-05-22
申请号：US10385206
申请日：2003-03-10
申请人： Christin Frederick , Haruo Saito
发明人： Christin Frederick , Haruo Saito
IPC分类号： C30B29/14
CPC分类号： C07K14/70589 , C07K2299/00 , G01N2333/70589
摘要： The crystal structures of CD45 and LAR, described herein, provide a basis for kinetic and functional studies. Identification of the crystal structures of cellular molecules is important in to determine functional roles in immunity, phosphorylation events, disease initiation mechanism. The isolated crystals and methods for crystallization thereof, are also important in identifying small molecule interactions with cellular molecules for new drug discovery.
摘要翻译：本文所述的CD45和LAR的晶体结构为动力学和功能研究提供了基础。鉴定细胞分子的晶体结构对于确定免疫，磷酸化事件，疾病发病机制中的功能作用是重要的。分离的晶体及其结晶方法在识别与细胞分子相互作用的新型药物发现方面也很重要。

4. 发明授权

US06895750B2 Nozzle vane driving control apparatus of variable nozzle turbocharger 有权
标题翻译：可变喷嘴涡轮增压器喷嘴叶片驱动控制装置
公开(公告)号：US06895750B2
公开(公告)日：2005-05-24
申请号：US10780910
申请日：2004-02-19
申请人： Yoshiyuki Ando , Takumi Arao , Takaaki Sekine , Haruo Saito
发明人： Yoshiyuki Ando , Takumi Arao , Takaaki Sekine , Haruo Saito
IPC分类号： F01D17/16 , F02B37/24 , H02K5/22 , H02K7/116 , H02K11/00 , F02D23/00
CPC分类号： H02K7/116 , F01D17/16 , F01D17/165 , F02B37/24 , F05D2220/40 , H02K5/225 , H02K11/00 , Y02T10/144
摘要： In a nozzle vane driving control apparatus of a variable nozzle turbocharger including an actuator for carrying out a driving operation for opening and closing a nozzle vane of a variable nozzle and an ECU for controlling the opening degree of the nozzle vane which is obtained by the actuator, an actuator cover for covering a pinion and reduction gears by interposing a base provided integrally with a motor case portion therebetween, a unit body accommodating each of control boards, a position sensor for detecting the rotating position of an output shaft and a connector having a terminal connecting a motor and each of the control boards, and a unit cover for covering the unit body are removably fastened and fixed with a bolt and are thus integrated with each other.
摘要翻译：一种可变喷嘴涡轮增压器的喷嘴叶片驱动控制装置，包括用于执行用于打开和关闭可变喷嘴的喷嘴叶片的驱动操作的致动器和用于控制由致动器获得的喷嘴叶片的开度的ECU ，用于通过将与其间的电动机壳体部分整体设置的基座相互覆盖小齿轮和减速齿轮的致动器盖，容纳每个控制板的单元体，用于检测输出轴的旋转位置的位置传感器和具有连接电动机和每个控制板的端子和用于覆盖单元主体的单元盖可拆卸地用螺栓紧固和固定，并因此彼此一体化。

5. 发明授权

US5977321A Heterodimeric T lymphocyte receptor subunit 失效
标题翻译：异二聚体T淋巴细胞受体亚单位
公开(公告)号：US5977321A
公开(公告)日：1999-11-02
申请号：US742539
申请日：1991-08-08
申请人： Haruo Saito , David M. Kranz , Herman N. Eisen , Susumu Tonegawa
发明人： Haruo Saito , David M. Kranz , Herman N. Eisen , Susumu Tonegawa
IPC分类号： C07K14/725 , C07K16/28
CPC分类号： C07K16/2809 , C07K14/7051
摘要： Disclosed is a heterodimeric T lymphocyte receptor subunit. The subunit consists of variable, joining, constant, transmembrane, and cytoplasmic regions.The structure, amino acid, and nucleotide sequence of the lymphocyte receptor subunit were determined using cDNA clones derived from a functional murine cytotoxic T lymphocyte clone. The genes corresponding to these cDNA are expressed and rearranged specifically in T cells and have significant sequence homologies to immunoglobulin V and C genes.T cell receptor subunits may be produced from the cDNA clones. The protein molecules may be further used for the production of T-cell clone specific antibodies.
摘要翻译：公开了异二聚体T淋巴细胞受体亚基。亚基由可变，连接，恒定，跨膜和胞质区组成。使用衍生自功能性鼠细胞毒性T淋巴细胞克隆的cDNA克隆测定淋巴细胞受体亚基的结构，氨基酸和核苷酸序列。与这些cDNA相对应的基因在T细胞中特异性表达和重排，并且与免疫球蛋白V和C基因具有显着的序列同源性。 T细胞受体亚基可以从cDNA克隆产生。蛋白质分子可以进一步用于生产T细胞克隆特异性抗体。

6. 发明申请

US20050022524A1 Variable nozzle control apparatus of turbocharger 有权
标题翻译：涡轮增压器可变喷嘴控制装置
公开(公告)号：US20050022524A1
公开(公告)日：2005-02-03
申请号：US10875825
申请日：2004-06-25
申请人： Yoshiyuki Ando , Haruo Saito , Takaaki Sekine
发明人： Yoshiyuki Ando , Haruo Saito , Takaaki Sekine
IPC分类号： F02B37/24 , F02D41/00 , F02D41/10 , F02D23/00
CPC分类号： F02B39/00 , F02B37/12 , F02B37/24 , F02D41/0007 , F02D41/10 , Y02T10/144
摘要： The invention provides a variable nozzle control apparatus for a turbocharger in an engine comprising: a variable nozzle having a vane; an engine ECU for identifying an operating situation of the engine by detected outputs of sensors in the engine and outputting a control signal; and an electronic control actuator for controlling an opening of the vane in response to the control signal transmitted from the engine ECU, wherein the electronic control actuator includes an electronic control circuit section for receiving an opening indication information of the vane from the engine ECU and outputting an output signal; a driving section for receiving the output signal from the electronic control circuit and driving the vane of the variable nozzle through an output shaft; and an angle sensor for detecting a rotation angle of the output shaft to output an actual angle signal of the output shaft to the electronic control circuit.
摘要翻译：本发明提供了一种用于发动机中的涡轮增压器的可变喷嘴控制装置，包括：具有叶片的可变喷嘴; 发动机ECU，用于通过发动机中的传感器的检测输出识别发动机的运行状况，并输出控制信号; 以及电子控制致动器，用于响应于从发动机ECU发送的控制信号来控制叶片的开度，其中电子控制致动器包括电子控制电路部分，用于从发动机ECU接收叶片的打开指示信息并输出输出信号; 用于从电子控制电路接收输出信号并通过输出轴驱动可变喷嘴的叶片的驱动部分; 以及用于检测输出轴的旋转角度以将输出轴的实际角度信号输出到电子控制电路的角度传感器。

7. 发明授权

US5398062A Video camera and camera system having an electronic viewfinder portraying image information 失效
标题翻译：具有电子取景器的摄像机和照相机系统描绘图像信息
公开(公告)号：US5398062A
公开(公告)日：1995-03-14
申请号：US896059
申请日：1992-06-09
申请人： Hiroyuki Hashimoto , Haruo Saito
发明人： Hiroyuki Hashimoto , Haruo Saito
IPC分类号： G03B17/20 , G03B17/48 , H04N5/232 , H04N5/225
CPC分类号： H04N5/23293 , G03B17/20 , G03B17/48
摘要： A video camera having a zoom function and a camera system are provided, wherein a ratio of view fields of the video camera and a photographic camera is calculated based on information about zooming powers of imaging lenses, and an image frame of the photographic cameras is displayed in a variable size at an electronic viewfinder in accordance with the ratio of the view fields and based on a picked-up image of fixed size, or a picked-up image is displayed in a variable size on the basis of the image frame of the photographic camera. View angles of the video camera and the photographic camera are obtained from the information about the zooming powers of the imaging lenses, and zoom adjustment is carried out with the view angles coinciding with each other, or the zooming power of one of the video camera and the photographic camera is adjusted such that the view angles become equal to each other. Accordingly, the view field of the photographic camera can be accurately recognized even if the zooming power is changed.
摘要翻译：提供具有变焦功能的摄像机和照相机系统，其中基于成像透镜的变焦功率的信息来计算摄像机和照相机的视场的比例，并且显示照相机的图像帧根据视场的比例和基于固定大小的拾取图像的电子取景器的可变尺寸，或者基于图像帧的可变尺寸显示拾取图像摄影相机。视频摄像机和照相机的视角是从关于成像透镜的变焦功率的信息获得的，并且以视角相互一致的方式进行变焦调整，或摄像机和摄像机之一的变焦功率调整照相机使得视角变得彼此相等。因此，即使改变变焦功率，也能够准确地识别照相机的视野。

8. 发明授权

US5189147A Meterodimeric T lymphocyte receptor antibody 失效
标题翻译：甲基二聚体T淋巴细胞受体抗体
公开(公告)号：US5189147A
公开(公告)日：1993-02-23
申请号：US271216
申请日：1988-11-14
申请人： Haruo Saito , David M. Kranz , Herman N. Eisen , Susumu Tonegawa
发明人： Haruo Saito , David M. Kranz , Herman N. Eisen , Susumu Tonegawa
IPC分类号： A61K39/00 , C07K14/725
CPC分类号： C07K14/7051 , A61K39/00
摘要： Disclosed is a heterodimeric T lymphocyte receptor comprising an alpha and a beta subunit. Each subunit consists of a signal peptide, variable, joining, constant, transmembrane, and cytoplasmic regions. The two subunits are connected by a disulfide bond between cysteine residues located between the constant and transmembrane region.The structure, amino acid, and nucleotide sequence of the lymphocyte receptor were determined using cDNA cones derived from a functional murine cytotoxic T lymphocyte clone. The genes corresponding to these cDNA are expressedThe U.S. government has rights in this invention by virtue of Grant No. NIH-5-POl-CA28900-04, NIH-5-P30-CA14051-13 and the Arthritis Foundation.
摘要翻译：公开了包含α和β亚基的异二聚体T淋巴细胞受体。每个亚基由信号肽，可变，连接，恒定，跨膜和细胞质区域组成。两个亚基通过位于恒定区和跨膜区之间的半胱氨酸残基之间的二硫键连接。使用衍生自功能性鼠细胞毒性T淋巴细胞克隆的cDNA锥来确定淋巴细胞受体的结构，氨基酸和核苷酸序列。与这些cDNA相对应的基因在T细胞中特异性表达和重排，并且与免疫球蛋白V和C基因具有显着的序列同源性。 T细胞受体蛋白及其亚基都可以从cDNA克隆产生。蛋白质分子可以进一步用于生产T细胞克隆特异性抗体。

9. 发明授权

US4987084A Method of testing the effect of a molecule on B lymphocyte function 失效
标题翻译：测试分子对B淋巴细胞功能的影响的方法
公开(公告)号：US4987084A
公开(公告)日：1991-01-22
申请号：US313108
申请日：1989-02-21
申请人： Thomas F. Tedder , Stuart F. Schlossman , Haruo Saito
发明人： Thomas F. Tedder , Stuart F. Schlossman , Haruo Saito
IPC分类号： G01N33/50 , G01N33/53 , G01N33/569
CPC分类号： G01N33/56972 , G01N33/5052
摘要： A method of testing the effect of an agonist or an antagonist to B lymphocyte cell surface protein CD20 on B lymphocyte function which involves determining calcium ion flux across the B lymphocyte membrane, contacting the B lymphocyte with the agonist or antagonist, and determining the change in calcium ion flux across the membrane after exposure of the B lymphocyte to the agonist or antagonist, is described. In preferred embodiments of the method the agonist or antagonist is a ligand that binds CD20 or an antibody to CD20.In other preferred embodiments, calcium ion flux is more preferably determined in terms of transmembrane current flow and most preferrably determined in terms of the change in cytosloic CA.sup.2+ concentration.

10. 发明授权

US08252273B2 Ultraviolet absorber 有权
标题翻译：紫外吸收剂
公开(公告)号：US08252273B2
公开(公告)日：2012-08-28
申请号：US12677900
申请日：2008-04-02
申请人： Masao Mori , Haruo Saito
发明人： Masao Mori , Haruo Saito
IPC分类号： A61K8/49 , A61K8/00 , C07C69/76
CPC分类号： C07C69/734 , A61K8/37 , A61Q17/04
摘要： There is provided an ultraviolet absorber having a strong absorptive capacity in the UVA range and an absorptive capacity in the UVB range to have an ultraviolet inhibitory effect in a wide range of wavelength, increasing in an ultraviolet absorptive capacity over the course of ultraviolet irradiation time in both the UVA and the UVB ranges and having an excellent solubility. An ultraviolet absorber comprising, as an active ingredient, a compound of General Formula I: (where —OA is an alkoxy group) that exhibits an ultraviolet A wave absorptive capacity which increases over time and that has an ultraviolet B wave absorptive capacity.
摘要翻译：提供了在UVA范围内具有强吸收能力的紫外线吸收剂和在UVB范围内的吸收能力，在宽波长范围内具有紫外线抑制作用，在紫外线照射时间内增加紫外线吸收能力 UVA和UVB两者都具有优异的溶解性。一种紫外线吸收剂，其特征在于，含有通式I的化合物（其中-OA为烷氧基），其表现出随时间而增加并具有紫外线B吸收能力的紫外线A吸收能力。

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