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    • 4. 发明申请
    • BIOFUNCTIONAL NANOFIBERS FOR ANALYTE SEPARATION IN MICROCHANNELS
    • 用于微通道分析分离的生物功能纳米微粒
    • US20140083859A1
    • 2014-03-27
    • US14007040
    • 2012-03-23
    • Antje J. BaeumnerMargaret W. FreyDaehwan Cho
    • Antje J. BaeumnerMargaret W. FreyDaehwan Cho
    • B81B1/00B81C1/00
    • B81B1/00B01L3/502707B01L2300/0681B01L2300/0816B81B1/006B81C1/00119
    • A method is provided for producing, in a substrate, an enclosed channel or enclosed cavity comprising at least one functional nanofiber, the method comprising the steps of providing a first substrate and a second substrate; forming a channel or cavity on the first substrate or the second substrate; electrospinning at least one functional nanofiber on the first substrate; assembling the first and second substrates, wherein the first substrate is placed over the second substrate, or the second substrate is placed over the first substrate; and bonding the first substrate and the second substrate to form the substrate, thereby forming an enclosed channel or enclosed cavity comprising the at least one functional nanofiber in the substrate. An enclosed channel or cavity comprising at least one functional electrospun nanofiber is also provided. A microfluidic device is also provided comprising an enclosed channel or cavity comprising at least one functional electrospun nanofiber.
    • 提供了一种在衬底中制造包含至少一种功能性纳米纤维的封闭通道或封闭腔的方法,所述方法包括以下步骤:提供第一衬底和第二衬底; 在所述第一基板或所述第二基板上形成通道或空腔; 在第一基底上静电纺丝至少一种功能性纳米纤维; 组装第一和第二基板,其中第一基板被放置在第二基板上,或者第二基板被放置在第一基板上; 以及接合所述第一基板和所述第二基板以形成所述基板,从而在所述基板中形成包含所述至少一个功能性纳米纤维的封闭通道或封闭空腔。 还提供了包括至少一个功能性电纺丝纳米纤维的封闭通道或空腔。 还提供了一种微流体装置,其包括包含至少一个功能性电纺丝纳米纤维的封闭通道或空腔。