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    • 1. 发明授权
    • Simplified peritoneal equilibration test for peritoneal dialysis
    • 腹膜透析简化腹膜平衡试验
    • US08180574B2
    • 2012-05-15
    • US12498847
    • 2009-07-07
    • Ying-Cheng LoAlp AkonurSarah Stobo Prichard
    • Ying-Cheng LoAlp AkonurSarah Stobo Prichard
    • G01N33/48G06F19/00
    • A61M1/28A61M1/1619
    • A simplified peritoneal equilibration test (S-PET) is disclosed. Instead of a lengthy peritoneal equilibration test (PET), the simplified procedure requires no blood sample and may use data from as few as two or three samples to classify a peritoneal membrane of a user. Typically, a peritoneal membrane or peritoneum of a dialysis patient, or other person, is classed as a high transport membrane, high-average transport membrane, a low-average transport membrane or a low transporter membrane. The S-PET may be performed at home by a user without the need to submit a blood sample. Kits for analyzing the samples may be furnished for home use. The kits may use disposable strips, microfluidic analyzers or chemical reagents, or may alternatively include reusable analysis equipment, such as optical or conductivity analysis equipment.
    • 公开了一种简化的腹膜平衡试验(S-PET)。 代替长时间的腹膜平衡试验(PET),简化的程序不需要血液样品,并且可以使用少至两个或三个样品的数据来分类用户的腹膜。 通常,透析患者或其他人的腹膜或腹膜被分类为高运输膜,高平均运输膜,低平均运输膜或低转运膜。 S-PET可以由用户在家进行,而不需要提交血样。 用于分析样品的试剂盒可供家庭使用。 试剂盒可以使用一次性条,微流控分析仪或化学试剂,或者可以替代地包括可重复使用的分析设备,例如光学或电导率分析设备。
    • 2. 发明申请
    • SIMPLIFIED PERITONEAL EQUILIBRATION TEST FOR PERITONEAL DIALYSIS
    • 简单的PERITONEAL EQUILIBRATION测试用于腹膜透析
    • US20110010101A1
    • 2011-01-13
    • US12498847
    • 2009-07-07
    • Ying-Cheng LoAlp AkonurSarah Stobo Prichard
    • Ying-Cheng LoAlp AkonurSarah Stobo Prichard
    • G06F19/00
    • A61M1/28A61M1/1619
    • A simplified peritoneal equilibration test (S-PET) is disclosed. Instead of a lengthy peritoneal equilibration test (PET), the simplified procedure requires no blood sample and may use data from as few as two or three samples to classify a peritoneal membrane of a user. Typically, a peritoneal membrane or peritoneum of a dialysis patient, or other person, is classed as a high transport membrane, high-average transport membrane, a low-average transport membrane or a low transporter membrane. The S-PET may be performed at home by a user without the need to submit a blood sample. Kits for analyzing the samples may be furnished for home use. The kits may use disposable strips, microfluidic analyzers or chemical reagents, or may alternatively include reusable analysis equipment, such as optical or conductivity analysis equipment.
    • 公开了一种简化的腹膜平衡试验(S-PET)。 代替长时间的腹膜平衡试验(PET),简化的程序不需要血液样品,并且可以使用少至两个或三个样品的数据来分类用户的腹膜。 通常,透析患者或其他人的腹膜或腹膜被分类为高运输膜,高平均运输膜,低平均运输膜或低转运膜。 S-PET可以由用户在家进行,而不需要提交血样。 用于分析样品的试剂盒可供家庭使用。 试剂盒可以使用一次性条,微流控分析仪或化学试剂,或者可以替代地包括可重复使用的分析设备,例如光学或电导率分析设备。
    • 9. 发明授权
    • Optimizing therapy outcomes for peritoneal dialysis
    • 优化腹膜透析治疗效果
    • US09348975B2
    • 2016-05-24
    • US12431458
    • 2009-04-28
    • Ying-Cheng LoAlp AkonurIsaac Martis
    • Ying-Cheng LoAlp AkonurIsaac Martis
    • G06F19/00A61M1/28
    • G06F19/3481A61M1/28A61M1/281A61M1/282A61M2205/3569A61M2205/52A61M2205/6018A61M2205/6054A61M2205/6072G06F19/00
    • Peritoneal dialysis therapy outcomes have been calculated for a variety of dwell times of peritoneal dialysis fluids in the peritoneal cavities of dialysis patients using kinetic modeling. The length of dwell time should not be the same for every patient, but should vary according to the patient condition and needs. Some patients have a potential for expressing greater ultrafiltrate into the dialysis fluid, and these patients can benefit from a longer dwell time, whereas other patients with less potential will not benefit from a longer dwell time. An optimal or peak time is observed for each peritoneal dialysis therapy outcome, such as ultrafiltrate volume rate, urea clearance (Kt/V), and creatinine clearance, while minimizing hydrocarbon absorption. These values and input parameters can be used to tailor the peritoneal dialysis dwell time for each patient, estimating the peak dwell time that will yield the best therapy outcome for each patient.
    • 已经使用动力学模型计算了透析患者腹膜腔腹膜透析液的各种停留时间的腹膜透析治疗结果。 每个患者的停留时间长度不应相同,但应根据患者情况和需要而变化。 一些患者有可能在透析液中表达更多的超滤液,这些患者可以从更长的停留时间中受益,而潜在的潜力较小的患者不会受益于更长的停留时间。 对于每个腹膜透析治疗结果,观察到最佳或高峰时间,例如超滤液体积率,尿素清除率(Kt / V)和肌酐清除率,同时使烃吸收最小化。 这些值和输入参数可用于定制每个患者的腹膜透析停留时间,估计将为每位患者产生最佳治疗结果的峰值停留时间。